Abstract
A selective dopamine (DA) sensor was developed using gold nanoparticles (Au-NPs) dispersed overoxidized-polyaniline (PANIox) based on a boron-doped diamond (BDD) thin-film electrode. The concentration of the DA was determined using voltammetry as a non-enzymatic sensor. BDD thin film has a high signal-to-noise ratio, a long-term stability, a high sensitivity, and a good reproducibility. PANI nanocomposites were directly synthesized on the BDD electrode and overoxidized using 0.5 M H2SO4 solution. The overoxidized PANI film enhances selectivity and sensitivity toward DA. The Au-NPs were dispersed on the PANI nanocomposite by electrochemical deposition. The nanometer-sized Au-NPs favor the sensing of DA in the presence of ascorbic acid (AA). The combination of the PANI with the Au-NPs and the BDD electrode can create synergetic effects for the performance of the biosensor, such as a fast response time, a lower detection limit, a wider linear range, enhanced selectivity, and higher sensitivity for the determination of DA.
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References
R. M. Wightman, C. Amatore, R. C. Engstrom, P. D. Hale, E. W. Kristensen, W. G. Kuhr, and L. J. May, Neuroscience, 1988, 25, 513.
P. Damier, E. C. Hirsch, Y. Agid, and A. M. Graybiel, Brain, 1999, 122, 1437.
J. I. Routh, R. E. Bannow, R. W. Fincham, and J. L. Stoll, Clin. Chem., 1971, 17, 867.
S. S. Kumar, J. Mathiyarasu, and K. L. Phani, J. Electroanal. Chem., 2005, 578, 95.
C. R. Raj, K. Tokuda, and T. Ohsaka, Bioelectrochemistry, 2001, 53, 183.
S. B. Hočevar, J. Wang, R. P. Deo, M. Musameh, and B. Ogorevc, Electroanalysis, 2005, 17, 417.
P. R. Roy, M. S. Saha, T. Okajima, S. G. Park, A. Fujishima, and T. Ohsaka, Electroanalysis, 2004, 16, 1777.
F. Shang, L. Zhou, K. A. Mahmoud, S. Hrapovic, Y. Liu, H. A. Moynihan, J. D. Glennon, and J. H. T. Luing, Anal. Chem., 2009, 81, 4089.
M. Wei, L. G. Sun, Z. Y. Xie, J. F. Zhii, A. Fujishima, Y. Einaga, D. G. Fu, X. M. Wang, and Z. Z. Gu, Adv. Funct. Mater., 2008, 18, 1414.
H. Wang, L. J. Wang, Z. F. Shi, Y. Guo, X. P. Cao, and H. L. Zhang, Electrochem. Commun., 2006, 8, 1779.
C. Levy-Clement, F. Zenia, N. A. Ndao, and A. Deneuville, New Diam. Front. Carbon Technol., 1999, 9, 189.
Y. L. Zhou, R. H. Tian, and J. F. Zhi, Biosens. Bioelectron., 2007, 22, 822.
J. Zhao, D. Wu, and J. Zhi, Bioelectrochemistry, 2009, 75, 44.
M. J. Song, S. W. Hwang, and D. Whang, J. Korean Phys. Soc., 2009, 54, 1612.
Y. Tang, K. Pan, X. Wang, C. Liu, and S. Luo, Microchim. Acta, 2010, 168, 231.
M. Nandi, R. Gangopadhyay, and A. Bhaumik, Microporous Mesoporous Mater., 2008, 109, 239.
H. Tang, A. Kitani, and M. Shiotani, Electrochim. Acta, 1996, 41, 1561.
F. J. Liu, L. M. Huang, T. C. Wen, and A. Gopalan, Synth. Met., 2007, 157, 651.
J. H. Kim, S. K. Lee, O. M. Kwon, S. I. Hong, and D. S. Lim, Diamond Relat. Mater., 2009, 18, 1218.
J. Weng, J. Xue, J. Wang, J. S. Ye, H. Cui, F. S. Sheu, and Q. Zhang, Adv. Funct. Mater., 2005, 15, 639.
S. Upadhyay, G. R. Rao, M. K. Sharma, B. K. Bhattacharya, V. K. Rao, and R. Vijayaraghavan, Biosens. Bioelectron., 2009, 25, 832.
X. Kang, J. Wang, H. Wu, I. A. Aksay, J. Liu, and Y. Lin, Biosens. Bioelectron., 2009, 25, 901.
T. Yin, W. Wei, and J. Zeng, Anal. Bioanal. Chem., 2006, 386, 2087.
A. Kraft, Int. J. Electrochem. Sci., 2007, 2, 355.
F. Shang, Y. Liu, S. Hrapovic, J. D. Glennon, and J. H. T. Luong, Analyst, 2009, 134, 519.
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Song, MJ., Lee, SK., Kim, JH. et al. Dopamine Sensor Based on a Boron-Doped Diamond Electrode Modified with a Polyaniline/Au Nanocomposites in the Presence of Ascorbic Acid. ANAL. SCI. 28, 583–587 (2012). https://doi.org/10.2116/analsci.28.583
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DOI: https://doi.org/10.2116/analsci.28.583