p.1343
p.1347
p.1351
p.1355
p.1359
p.1363
p.1367
p.1371
p.1375
A Novel Microcantilever Device with Nano-Interdigitated Electrodes (Nano-IDEs) for Biosensing Applications
Abstract:
We present a novel microcantilever device with nano-interdigitated electrodes (nano-IDEs) and selective functionalization of nano-IDEs for biosensing applications. The nano-IDEs play a role in precisely addressing capture molecules to a specific region on a microcantilever. This leads to a detectable surface stress due to the binding of target molecules. 70~500 nm-wide gold (Au) nano- IDEs are fabricated on a low-stress SiNx microcantilever with dimensions of 100~600 μm in length, and 15~60 μm in width, with a 0.5 μm thickness using electron beam lithography and bulk micromachining. 32~96 nm-thick streptavidin is selectively deposited on one side of nano-IDEs using cyclic voltammetry at a scan rate of 0.1 V/s with a range of -0.2~0.7 V during 1~5 cycles. The selective deposition of streptavidin is confirmed by fluorescence microscopy and atomic force microscopy (AFM).
Info:
Periodical:
Pages:
1359-1362
Citation:
Online since:
December 2006
Authors:
Price:
Permissions: