Journal of
Medicinal Plants Research

  • Abbreviation: J. Med. Plants Res.
  • Language: English
  • ISSN: 1996-0875
  • DOI: 10.5897/JMPR
  • Start Year: 2007
  • Published Articles: 3834

Full Length Research Paper

Chemical composition, antimicrobial and anti-acetylcholinesterase activities of essential oil from Lantana camara (Verbenaceae) flowers

Ricardo Carvalho dos Santos*
  • Ricardo Carvalho dos Santos*
  • Post-Graduate in Biodiversity and Biotechnology Program, Bionorte, State Coordination of Roraima, Federal University of Roraima - UFRR, Campus Cauamé, BR 174, Km 12, District Monte Cristo, CEP 69310-250, Boa Vista-RR-Brazil.
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Antonio Alves de Melo Filho
  • Antonio Alves de Melo Filho
  • 1Post-Graduate in Biodiversity and Biotechnology Program, Bionorte, State Coordination of Roraima, Federal University of Roraima - UFRR, Campus Cauamé, BR 174, Km 12, District Monte Cristo, CEP 69310-250, Boa Vista-RR-Brazil. 2Post-Graduate in Chemistry Program, Center for Research and Post-Graduate Studies in Science and Technology, NPPGCT, UFRR, Av Capitão Ene Garcez, n. 2413, Campus Paricarana, CEP 69310-000, Boa Vista-RR-Brazil. Chromatography Laboratory, Institute of Exact Sciences, Department of Chemistry, UFMG, Belo Horizonte-MG-Brazil.
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Edvan Alves Chagas
  • Edvan Alves Chagas
  • Embrapa - Brazilian Agricultural Research Corporation. Rodovia 174, Km 8, Industrial District, CEP 69301-970, Boa Vista-RR-Brazil.
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Jacqueline Aparecida Takahashi
  • Jacqueline Aparecida Takahashi
  • Institute of Exact Sciences, Department of Chemistry, Federal University of Minas Gerais, UFMG, Av Antonio Carlos, n. 6627, Pampulha, CEP 31270-901, Belo Horizonte-MG-Brazil.
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Vany Perpetua Ferraz
  • Vany Perpetua Ferraz
  • Chromatography Laboratory, Institute of Exact Sciences, Department of Chemistry, UFMG, Belo Horizonte-MG-Brazil.
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Ismael Montero Fernández
  • Ismael Montero Fernández
  • Post-Graduate in Chemistry Program, Center for Research and Post-Graduate Studies in Science and Technology, NPPGCT, UFRR, Av Capitão Ene Garcez, n. 2413, Campus Paricarana, CEP 69310-000, Boa Vista-RR-Brazil.
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Pedro Romulo Estevam Ribeiro
  • Pedro Romulo Estevam Ribeiro
  • Post-Graduate in Chemistry Program, Center for Research and Post-Graduate Studies in Science and Technology, NPPGCT, UFRR, Av Capitão Ene Garcez, n. 2413, Campus Paricarana, CEP 69310-000, Boa Vista-RR-Brazil.
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Ana Cristina Gonçalves Reis de Melo
  • Ana Cristina Gonçalves Reis de Melo
  • Post-Graduate in Chemistry Program, Center for Research and Post-Graduate Studies in Science and Technology, NPPGCT, UFRR, Av Capitão Ene Garcez, n. 2413, Campus Paricarana, CEP 69310-000, Boa Vista-RR-Brazil.
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Luciana Chaves Holanda
  • Luciana Chaves Holanda
  • Post-Graduate in Chemistry Program, Center for Research and Post-Graduate Studies in Science and Technology, NPPGCT, UFRR, Av Capitão Ene Garcez, n. 2413, Campus Paricarana, CEP 69310-000, Boa Vista-RR-Brazil.
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  •  Received: 02 August 2015
  •  Accepted: 28 August 2015
  •  Published: 17 September 2015

Abstract

Lantana camara L. is considered a weed, but is used in agriculture and traditional medicine due to its different pharmacological effects. The objective of this study was to determine the chemical composition and the bioactivity of essential oil from L. camara flowers collected in Boa Vista, Roraima, Brazil. Essential oil was obtained using a Clevenger type apparatus. The oil obtained was analyzed by gas chromatography coupled to flame ionization detector (GC-FID) and gas chromatography coupled to mass spectrometer detector (GC-MS) and its bioactivity was assayed against fungi and bacteria, as well as for acetylcholinesterase inhibition. The chemical composition of essential oil presented major compounds contrasting with the literature, while its bactericidal and fungicidal activity was excellent, reaching over than 90% inhibition against yeast. A potent anti-acetylcholinesterase activity, superior than 77% inhibition, was also observed.

 

Keywords: Lantana camara, flowers essential oil, antiacetylcholinesterase, antimicrobial

Abbreviation

AChE, Acetycholinesterase; GC-FID, gas chromatography using flame ionization detector; AD, Alzheimer's disease.

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This article is published under the terms of the Creative Commons Attribution License 4.0

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