The objective of the present study is to investigate the effect of randomly distributed tire chips, derived from waste tires on the durability of reference mix containing fly ash, lime and gypsum. The dry, water, sodium hydroxide and carbon tetra chloride treated tire chips were used in the study. The tire chip content was varied from 5% to 15% and specimen were cured for 7, 28, 90, and 180 days with two different curing methods (in a dessicator and water filled container). The results of the study revealed that the weight loss of reference mix mixed with dry tire chips can be decreased with treatment with water, sodium hydroxide and carbon tetra chloride. Decrease in weight loss was highest with carbon tetra chloride followed by sodium hydroxide and water. Further, the weight loss of reference mix with dry/treated tire chip decreased with the increase in curing period and the decrease was highest when specimens were cured in water filled container. The weight loss of the reference mix mixed with dry/treated tire chips increased with the increase in tire chip content. Leachate analysis have shown that reference mix mixed with dry/treated tire chips does not cause leaching of any harmful metals. Potential use of this material can be in road subbases having light traffic.