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2013 | OriginalPaper | Buchkapitel

4. Liposomes for DNA Nanotechnology: Preparation, Properties, and Applications

verfasst von : Neeshma Dave, Juewen Liu

Erschienen in: DNA Nanotechnology

Verlag: Springer Berlin Heidelberg

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Abstract

Over the past two decades, DNA has become a major player in nanotechnology. A very interesting and useful method uses DNA to link various nanoparticles, where the programmable structure and molecular recognition function of DNA are coupled to the optical, electric, magnetic, and catalytic property of the nanomaterials. Compared to many inorganic nanoparticles, liposomes are self-assembled soft matters that possess surface fluidity and the potential for molecular containment. The charge, size, and phase transition properties of liposomes can be precisely tuned by varying liposome formulation. In this chapter, we describe methods for liposome preparation and DNA attachment. We also discuss the biophysical properties of DNA-functionalized liposomes and their emerging applications in DNA-directed assembly, biosensor development, and drug delivery.

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Metadaten
Titel
Liposomes for DNA Nanotechnology: Preparation, Properties, and Applications
verfasst von
Neeshma Dave
Juewen Liu
Copyright-Jahr
2013
Verlag
Springer Berlin Heidelberg
DOI
https://doi.org/10.1007/978-3-642-36077-0_4

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