REMUS is a coarse-grained reconfigurable computing system for multimedia and communication baseband processing. Fractional motion estimation (FME) is one of several tools which contribute to H.264/AVC’s excellent coding efficiency. ASIC-based hardware accelerators for FME are indispensable in real-time video encoding applications in the past. The paper introduces the mapping of H.264/AVC FME algorithm onto platform of REMUS system in order to demonstrate that complex applications can be mapped with competitive performance onto REMUS platform. Experimental results show that the REMUS can perform FME at real-time speed for CIF/SDTV@30fps video sequences with one reference frame. The implementation method therefore can apply for H.264/AVC encoder in mobile multimedia applications. REMUS system is designed and synthesized by using TSMC 65nm low power technology. The die size of REMUS is 23.7 mm
. REMUS consumes about 194mW while working at 200MHz.