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Erschienen in:
Global Nonlinear Fitness Function for Protein Structures Kapitel lesen Erstes Kapitel lesen

2017 | OriginalPaper | Buchkapitel

Metagenomics for Monitoring Environmental Biodiversity: Challenges, Progress, and Opportunities

verfasst von : Raghu Chandramohan, Cheng Yang, Yunpeng Cai, May D. Wang

Erschienen in: Health Informatics Data Analysis

Verlag: Springer International Publishing

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Abstract

Metagenomics, as the genomic analysis of DNA materials from environmental samples containing multiple genomic components, is attracting more and more interests due to its wide applications on microbial, cancer, and immunology researches. This chapter provides an overview on the topic covering the major steps involved in data collection, processing, and analysis. We describe and discuss experiment design, sample processing and quality control, sequencing and assembly, annotation, and downstream analyses. For each step, we summarize the current points of views, key issues, and popular tools. A step-by-step tutorial is then given using the popular QIIME pipeline on a bacterial 16S rRNA study case, which would benefit new scientists of the field for the startup of a successful metagenome project.

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Vorheriges Kapitel Metabolomics Characterization of Human Diseases
Nächstes Kapitel Clinical Assessment of Disease Risk Factors Using SNP Data and Bayesian Methods
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Metadaten
Titel
Metagenomics for Monitoring Environmental Biodiversity: Challenges, Progress, and Opportunities
verfasst von
Raghu Chandramohan
Cheng Yang
Yunpeng Cai
May D. Wang
Copyright-Jahr
2017
Buch
Health Informatics Data Analysis

Print ISBN: 978-3-319-44979-1

Electronic ISBN: 978-3-319-44981-4

Copyright-Jahr: 2017

DOI
https://doi.org/10.1007/978-3-319-44981-4_5