3. Multi-wave EM-Acoustic Applications

In this chapter, several interesting applications of the EM-Acoustic sensing and imaging will be introduced with innovative approach. In Sect. 3.1, a correlated microwave-acoustic imaging approach is proposed by fusing scattered microwave and thermoacoustic image to deliver higher image contrast for early-stage breast cancer detection, which is proved with numerical simulation results. In Sect. 3.2, a novel single-wavelength approach is proposed to detect the blood oxygen saturation (SO₂), where both scattered optical wave and photoacoustic wave are collected and correlated. Phantom studies are performed to validate its feasibility. In Sect. 3.3, a photoacoustic-guided depth-resolved Raman spectroscopy approach is proposed for skin cancer diagnosis, which is experimentally validated on multi-layer phantom. In Sect. 3.4, a multistatic photoacoustic classification approach is proposed to characterize malignant and benign tumors, which is challenging for conventional photoacoustic tomography for deep tissue imaging.