Because they behaved with me at random, I will as well behave with them at random.—Leviticus 26:40-41 1
What We Are Talking About when We Talk About Noise and (Synthetic) Biology
Case Studies on Noise and Synthetic Biology
that it hinges on a criterion that isn’t satisfied in many biological systems, namely that the inhibitor must be able to move much more quickly than the activator. For example, if instead of chemicals, we were looking at two creatures in an ecosystem, like wolves and sheep, the wolves would need be able to move around much faster than the sheep to get classic Turing patterns. What this would look like, you would first see the sheep grow in number, feeding the wolves, which would then also grow in number. And the wolves would run around and contain the sheep, so that you would get little localized patches of sheep with the wolves on the outside. That’s essentially the mechanism in animal terms for what Turing discovered. [ 33]
what happens if there is only a small number of sheep, so that there are large fluctuations in population numbers? Now you get processes where sheep die at random. And we discovered, when you give birth to randomness, that actually drives the formation of stochastic Turing patterns.” […] “The theory of stochastic Turing patterns doesn’t require a great difference in speed between the prey and the predator, the activator and the inhibitor. They can be more or less the same, and you still get a pattern. But it won’t be a regular pattern. It’ll be disordered in some way. [ 33]
Distinction Between Intrinsic/Extrinsic Noise and Stochastic Pulsing
The “Information Metaphor Falsehood” and the Glorification of Noise
[T]he adoption of information in biology is an erroneous transposition from a specific mathematical domain to one where it does not belong. Indeed, the mathematical framework of the information theory is too rigid and discrete to fit with biological phenomena. Therefore, information in biology represents an inappropriate metaphor.
Where Is Noise Located?
I saw the earth in the Aleph and in the earth the Aleph once more and the earth in the Aleph… ([ 46], p. 151)
Final Remarks on the Definitional Spectrum of Noise
… alternative epistemology of living beings which accounts for the structures of determination inherent to biology and for an autonomous definition of randomness sticking to this idea, history and contexts, as well as internal constraints of integration and regulation mechanisms, can be thought to constrain possible evolutionary paths that dynamically arise in the interaction with the environment rather than to determine the outcome (as determinism requires that the same effects derive from the same causes). ([ 16], p. 9)