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Erschienen in:
An Overview of Point-of-Care Technologies Enabling Next-Generation Healthcare Monitoring and Management Kapitel lesen Erstes Kapitel lesen

2019 | OriginalPaper | Buchkapitel

5. Paper-Based Point-of-Care Immunoassays

verfasst von : Sandeep Kumar Vashist

Erschienen in: Point-of-Care Technologies Enabling Next-Generation Healthcare Monitoring and Management

Verlag: Springer International Publishing

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Abstract

Paper-based point-of-care (POC) immunoassays (IA) enable the detection of analytes at the remote, decentralized, and personalized settings. Based on their low-cost, simplicity, and rapid analyte detection, they are ideal for POC diagnostic applications in developing countries, which have limited healthcare resources, personnel, and infrastructure. They obviate the limitations of conventional immunodiagnostic assays and the upcoming automated immunoassays, such as the need for highly-skilled analysts, costly infrastructure, bulky and expensive instruments, continuous power supply, and complex process steps. The emerging trend is toward the development of fully-integrated paper-based IAs (PIAs) that can be read by smartphones (SP) or smart readers. This chapter discusses the various PIAs that have been developed to date together with the future trends and challenges.

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Vorheriges Kapitel Point-of-Care Diabetes Management Softwares and Smart Applications
Nächstes Kapitel Lab-on-a-Chip-Based Point-of-Care Immunoassays
Literatur
1.
Vashist SK, Luong JHT. Handbook of immunoassay technologies: approaches, performances, and applications. London: Academic Press; 2018.
2.
Ahmed S, Bui MP, Abbas A. Paper-based chemical and biological sensors: engineering aspects. Biosens Bioelectron. 2016;77:249–63.CrossRef
3.
Chen Y-H, Kuo Z-K, Cheng C-M. Paper–a potential platform in pharmaceutical development. Trends Biotech. 2015;33(1):4–9.CrossRef
4.
Ge L, Yu J, Ge S, Yan M. Lab-on-paper-based devices using chemiluminescence and electrogenerated chemiluminescence detection. Anal Bioanal Chem. 2014;406(23):5613–30.CrossRef
5.
Hu J, Wang S, Wang L, Li F, Pingguan-Murphy B, Lu TJ, et al. Advances in paper-based point-of-care diagnostics. Biosens Bioelectron. 2014;54:585–97.CrossRef
6.
Liana DD, Raguse B, Gooding JJ, Chow E. Recent advances in paper-based sensors. Sensors. 2012;12(9):11505–26.CrossRef
7.
Martinez AW, Phillips ST, Whitesides GM, Carrilho E. Diagnostics for the developing world: microfluidic paper-based analytical devices. Anal Chem. 2009;82(1):3–10.CrossRef
8.
Parolo C, Merkoci A. Paper-based nanobiosensors for diagnostics. Chem Soc Rev. 2013;42(2):450–7.CrossRef
9.
Pelton R. Bioactive paper provides a low-cost platform for diagnostics. Trends Anal Chem. 2009;28(8):925–42.CrossRef
10.
Rolland JP, Mourey DA. Paper as a novel material platform for devices. MRS Bull. 2013;38(04):299–305.CrossRef
11.
Then WL, Garnier G. Paper diagnostics in biomedicine. Rev Anal Chem. 2013;32(4):269–94.CrossRef
12.
Li X, Ballerini DR, Shen W. A perspective on paper-based microfluidics: current status and future trends. Biomicrofluidics. 2012;6(1):11301–1130113.CrossRef
13.
Jaganathan S, Vahedi Tafreshi H, Pourdeyhimi B. Modeling liquid porosimetry in modeled and imaged 3-D fibrous microstructures. J Colloid Interface Sci. 2008;326(1):166–75.CrossRef
14.
15.
Yetisen AK, Akram MS, Lowe CR. Paper-based microfluidic point-of-care diagnostic devices. Lab Chip. 2013;13(12):2210–51.CrossRef
16.
Wong R, Tse H. Lateral flow immunoassay. New York: Humana Press; 2009.CrossRef
17.
Han YL, Wang W, Hu J, Huang G, Wang S, Lee WG, et al. Benchtop fabrication of three-dimensional reconfigurable microfluidic devices from paper-polymer composite. Lab Chip. 2013;13(24):4745–9.CrossRef
18.
Park S, Mohanty N, Suk JW, Nagaraja A, An J, Piner RD, et al. Biocompatible, robust free-standing paper composed of a TWEEN/graphene composite. Adv Mater. 2010;22(15):1736–40.CrossRef
19.
Nanomaterials SB. Paper powers battery breakthrough. Nat Nanotechnol. 2007;2(10):598–9.CrossRef
20.
Wang DW, Li F, Zhao J, Ren W, Chen ZG, Tan J, et al. Fabrication of graphene/polyaniline composite paper via in situ anodic electropolymerization for high-performance flexible electrode. ACS Nano. 2009;3(7):1745–52.CrossRef
21.
Chen X, Chen J, Wang F, Xiang X, Luo M, Ji X, et al. Determination of glucose and uric acid with bienzyme colorimetry on microfluidic paper-based analysis devices. Biosens Bioelectron. 2012;35(1):363–8.CrossRef
22.
He M, Liu Z. Paper-based microfluidic device with upconversion fluorescence assay. Anal Chem. 2013;85(24):11691–4.CrossRef
23.
Lei KF, Yang S-I, Tsai S-W, Hsu H-T. Paper-based microfluidic sensing device for label-free immunoassay demonstrated by biotin–avidin binding interaction. Talanta. 2015;134:264–70.CrossRef
24.
Li X, Tian J, Shen W. Quantitative biomarker assay with microfluidic paper-based analytical devices. Anal Bioanal Chem. 2010;396(1):495–501.CrossRef
25.
Liu F, Zhang C. A novel paper-based microfluidic enhanced chemiluminescence biosensor for facile, reliable and highly-sensitive gene detection of Listeria monocytogenes. Sens Actuators B Chem. 2015;209:399–406.CrossRef
26.
Mao X, Huang TJ. Microfluidic diagnostics for the developing world. Lab Chip. 2012;12(8):1412–6.CrossRef
27.
Martinez AW, Phillips ST, Carrilho E, Thomas SW 3rd, Sindi H, Whitesides GM. Simple telemedicine for developing regions: camera phones and paper-based microfluidic devices for real-time, off-site diagnosis. Anal Chem. 2008;80(10):3699–707.CrossRef
28.
Martinez AW, Phillips ST, Whitesides GM. Three-dimensional microfluidic devices fabricated in layered paper and tape. Proc Natl Acad Sci U S A. 2008;105(50):19606–11.CrossRef
29.
Mu X, Zhang L, Chang S, Cui W, Zheng Z. Multiplex microfluidic paper-based immunoassay for the diagnosis of hepatitis C virus infection. Anal Chem. 2014;86(11):5338–44.CrossRef
30.
Noiphung J, Songjaroen T, Dungchai W, Henry CS, Chailapakul O, Laiwattanapaisal W. Electrochemical detection of glucose from whole blood using paper-based microfluidic devices. Anal Chim Acta. 2013;788:39–45.CrossRef
31.
Rattanarat P, Dungchai W, Cate DM, Siangproh W, Volckens J, Chailapakul O, et al. A microfluidic paper-based analytical device for rapid quantification of particulate chromium. Anal Chim Acta. 2013;800:50–5.CrossRef
32.
Schilling KM, Lepore AL, Kurian JA, Martinez AW. Fully enclosed microfluidic paper-based analytical devices. Anal Chem. 2012;84(3):1579–85.CrossRef
33.
Wu Y, Xue P, Hui KM, Kang Y. A paper-based microfluidic electrochemical immunodevice integrated with amplification-by-polymerization for the ultrasensitive multiplexed detection of cancer biomarkers. Biosens Bioelectron. 2014;52:180–7.CrossRef
34.
Yu J, Wang S, Ge L, Ge S. A novel chemiluminescence paper microfluidic biosensor based on enzymatic reaction for uric acid determination. Biosens Bioelectron. 2011;26(7):3284–9.CrossRef
35.
Zhao C, Thuo MM, Liu X. A microfluidic paper-based electrochemical biosensor array for multiplexed detection of metabolic biomarkers. Sci Technol Adv Mater. 2013;14(5):054402.CrossRef
36.
Hu J, Wang L, Li F, Han YL, Lin M, Lu TJ, et al. Oligonucleotide-linked gold nanoparticle aggregates for enhanced sensitivity in lateral flow assays. Lab Chip. 2013;13(22):4352–7.CrossRef
37.
Fu E, Ramsey SA, Kauffman P, Lutz B, Yager P. Transport in two-dimensional paper networks. Microfluid Nanofluidics. 2011;10(1):29–35.CrossRef
38.
Song MB, Joung HA, Oh YK, Jung K, Ahn YD, Kim MG. Tear-off patterning: a simple method for patterning nitrocellulose membranes to improve the performance of point-of-care diagnostic biosensors. Lab Chip. 2015;15(14):3006–12.CrossRef
39.
Noh H, Phillips ST. Fluidic timers for time-dependent, point-of-care assays on paper. Anal Chem. 2010;82(19):8071–8.CrossRef
40.
Carrilho E, Martinez AW, Whitesides GM. Understanding wax printing: a simple micropatterning process for paper-based microfluidics. Anal Chem. 2009;81(16):7091–5.CrossRef
41.
Zhong Z, Wang Z, Huang G. Investigation of wax and paper materials for the fabrication of paper-based microfluidic devices. Microsyst Technol. 2012;18(5):649–59.CrossRef
42.
Lu Y, Shi W, Qin J, Lin B. Fabrication and characterization of paper-based microfluidics prepared in nitrocellulose membrane by wax printing. Anal Chem. 2009;82(1):329–35.CrossRef
43.
Martinez AW, Phillips ST, Butte MJ, Whitesides GM. Patterned paper as a platform for inexpensive, low-volume, portable bioassays. Angew Chem Int Ed. 2007;46(8):1318–20.CrossRef
44.
Free AH, Adams EC, Kercher ML, Free HM, Cook MH. Simple specific test for urine glucose. Clin Chem. 1957;3(3):163–8.
45.
Glad C, Grubb AO. Immunocapillary migration—a new method for immunochemical quantitation. Anal Biochem. 1978;85(1):180–7.CrossRef
46.
Vaitukaitis JL, Braunstein GD, Ross GT. A radioimmunoassay which specifically measures human chorionic gonadotropin in the presence of human luteinizing hormone. Am J Obstet Gynecol. 1972;113(6):751–8.CrossRef
47.
Hawkes R, Niday E, Gordon J. A dot-immunobinding assay for monoclonal and other antibodies. Anal Biochem. 1982;119(1):142–7.CrossRef
48.
Le S, Zhou H, Nie J, Cao C, Yang J, Pan H, et al. Fabrication of paper devices via laser-heating-wax-printing for high-tech enzyme-linked immunosorbent assays with low-tech pen-type pH meter readout. Analyst. 2017;142(3):511–6.CrossRef
49.
Vashist SK, Luppa PB, Yeo LY, Ozcan A, Luong JHT. Emerging technologies for next-generation point-of-care testing. Trends Biotechnol. 2015;33(11):692–705.CrossRef
50.
Young RO, Young SR. The pH miracle: balance your diet, reclaim your health. New York: Hachette UK; 2008.
51.
Cheng CM, Martinez AW, Gong J, Mace CR, Phillips ST, Carrilho E, et al. Paper-based ELISA. Angew Chem Int Ed Engl. 2010;49(28):4771–4.CrossRef
52.
Tian J, Li X, Shen W. Printed two-dimensional micro-zone plates for chemical analysis and ELISA. Lab Chip. 2011;11(17):2869–75.CrossRef
53.
Avrameas S, Ternynck T. Enzyme-linked immunosorbent assay (ELISA). 1998.
54.
O’Connor EF, Paterson S, De La Rica R. Naked-eye detection as a universal approach to lower the limit of detection of enzyme-linked immunoassays. Anal Bioanal Chem. 2016;408(13):3389–93.CrossRef
55.
Bahadır EB, Sezgintürk MK. Lateral flow assays: principles, designs and labels. Trends Anal Chem. 2016;82:286–306.CrossRef
56.
Koczula KM, Gallotta A. Lateral flow assays. Essays Biochem. 2016;60(1):111–20.CrossRef
57.
Daniel MC, Astruc D. Gold nanoparticles: assembly, supramolecular chemistry, quantum-size-related properties, and applications toward biology, catalysis, and nanotechnology. Chem Rev. 2004;104(1):293–346.CrossRef
58.
Lin M, Zhao Y, Wang S, Liu M, Duan Z, Chen Y, et al. Recent advances in synthesis and surface modification of lanthanide-doped upconversion nanoparticles for biomedical applications. Biotechnol Adv. 2012;30(6):1551–61.CrossRef
59.
Ge C, Yu L, Fang Z, Zeng L. An enhanced strip biosensor for rapid and sensitive detection of histone methylation. Anal Chem. 2013;85(19):9343–9.CrossRef
60.
Nie Z, Nijhuis CA, Gong J, Chen X, Kumachev A, Martinez AW, et al. Electrochemical sensing in paper-based microfluidic devices. Lab Chip. 2010;10(4):477–83.CrossRef
61.
Turner AP. Biosensors: sense and sensibility. Chem Soc Rev. 2013;42(8):3184–96.CrossRef
62.
Yang Q, Gong X, Song T, Yang J, Zhu S, Li Y, et al. Quantum dot-based immunochromatography test strip for rapid, quantitative and sensitive detection of alpha fetoprotein. Biosens Bioelectron. 2011;30(1):145–50.CrossRef
63.
van den Berk GE, Frissen PH, Regez RM, Rietra PJ. Evaluation of the rapid immunoassay determine HIV 1/2 for detection of antibodies to human immunodeficiency virus types 1 and 2. J Clin Microbiol. 2003;41(8):3868–9.CrossRef
64.
Sajid M, Kawde A-N, Daud M. Designs, formats and applications of lateral flow assay: a literature review. J Saudi Chem Soc. 2015;19(6):689–705.CrossRef
65.
Liu W, Cassano CL, Xu X, Fan ZH. Laminated paper-based analytical devices (LPAD) with origami-enabled chemiluminescence immunoassay for cotinine detection in mouse serum. Anal Chem. 2013;85(21):10270–6.CrossRef
66.
Xia Y, Si J, Li Z. Fabrication techniques for microfluidic paper-based analytical devices and their applications for biological testing: a review. Biosens Bioelectron. 2016;77:774–89.CrossRef
67.
Nilghaz A, Wicaksono DH, Gustiono D, Majid FAA, Supriyanto E, Kadir MRA. Flexible microfluidic cloth-based analytical devices using a low-cost wax patterning technique. Lab Chip. 2012;12(1):209–18.CrossRef
68.
Cassano CL, Fan ZH. Laminated paper-based analytical devices (LPAD): fabrication, characterization, and assays. Microfluidic Nanofluidics. 2013;15(2):173–81.CrossRef
69.
Martinez AW, Phillips ST, Whitesides GM. Three-dimensional microfluidic devices fabricated in layered paper and tape. Proc Natl Acad Sci. 2008;105(50):19606–11.CrossRef
70.
Lewis GG, DiTucci MJ, Baker MS, Phillips ST. High throughput method for prototyping three-dimensional, paper-based microfluidic devices. Lab Chip. 2012;12(15):2630–3.CrossRef
71.
Schilling KM, Jauregui D, Martinez AW. Paper and toner three-dimensional fluidic devices: programming fluid flow to improve point-of-care diagnostics. Lab Chip. 2013;13(4):628–31.CrossRef
72.
Liu H, Crooks RM. Three-dimensional paper microfluidic devices assembled using the principles of origami. J Am Chem Soc. 2011;133(44):17564–6.CrossRef
73.
Liu X, Cheng C, Martinez A, Mirica K, Li X, Phillips S, et al., editors. A portable microfluidic paper-based device for ELISA. Micro Electro Mechanical Systems (MEMS), 2011 IEEE 24th International Conference on. IEEE; 2011.
74.
Apilux A, Ukita Y, Chikae M, Chailapakul O, Takamura Y. Development of automated paper-based devices for sequential multistep sandwich enzyme-linked immunosorbent assays using inkjet printing. Lab Chip. 2013;13(1):126–35.CrossRef
75.
Nie Z, Deiss F, Liu X, Akbulut O, Whitesides GM. Integration of paper-based microfluidic devices with commercial electrochemical readers. Lab Chip. 2010;10(22):3163–9.CrossRef
76.
Lu J, Ge S, Ge L, Yan M, Yu J. Electrochemical DNA sensor based on three-dimensional folding paper device for specific and sensitive point-of-care testing. Electrochim Acta. 2012;80:334–41.CrossRef
77.
Huang X, Aguilar ZP, Xu H, Lai W, Xiong Y. Membrane-based lateral flow immunochromatographic strip with nanoparticles as reporters for detection: a review. Biosens Bioelectron. 2016;75:166–80.CrossRef
78.
Rivasa L, Medina-Sáncheza M, de la Escosura-Muñiza A, Merkoçi A. Improving sensitivity of gold nanoparticles-based lateral flow assays by using wax-printed pillars as delay barriers of microfluidics. Lab Chip. 2014;14:4406–14.CrossRef
79.
Posthuma-Trumpie GA, Wichers JH, Koets M, Berendsen LB, van Amerongen A. Amorphous carbon nanoparticles: a versatile label for rapid diagnostic (immuno)assays. Anal Bioanal Chem. 2012;402(2):593–600.CrossRef
80.
Wang D-B, Tian B, Zhang Z-P, Deng J-Y, Cui Z-Q, Yang R-F, et al. Rapid detection of Bacillus anthracis spores using a super-paramagnetic lateral-flow immunological detectionsystem. Biosens Bioelectron. 2013;42:661–7.CrossRef
81.
Wang S, Ge L, Song X, Yu J, Ge S, Huang J, et al. Paper-based chemiluminescence ELISA: lab-on-paper based on chitosan modified paper device and wax-screen-printing. Biosens Bioelectron. 2012;31(1):212–8.CrossRef
82.
Li X, Zwanenburg P, Liu X. Magnetic timing valves for fluid control in paper-based microfluidics. Lab Chip. 2013;13(13):2609–14.CrossRef
83.
Zhou W, Gao X, Liu D, Chen X. Gold nanoparticles for in vitro diagnostics. Chem Rev. 2015;115(19):10575–636.CrossRef
84.
Quesada-Gonzalez D, Merkoci A. Nanoparticle-based lateral flow biosensors. Biosens Bioelectron. 2015;73:47–63.CrossRef
85.
Safenkova I, Zherdev A, Dzantiev B. Factors influencing the detection limit of the lateral-flow sandwich immunoassay: a case study with potato virus X. Anal Bioanal Chem. 2012;403(6):1595–605.CrossRef
86.
Parolo C, de la Escosura-Muniz A, Merkoci A. Enhanced lateral flow immunoassay using gold nanoparticles loaded with enzymes. Biosens Bioelectron. 2013;40(1):412–6.CrossRef
87.
Shen G, Zhang S, Hu X. Signal enhancement in a lateral flow immunoassay based on dual gold nanoparticle conjugates. Clin Biochem. 2013;46(16–17):1734–8.CrossRef
88.
Xu H, Chen J, Birrenkott J, Zhao JX, Takalkar S, Baryeh K, et al. Gold-nanoparticle-decorated silica nanorods for sensitive visual detection of proteins. Anal Chem. 2014;86(15):7351–9.CrossRef
89.
Tang D, Sauceda JC, Lin Z, Ott S, Basova E, Goryacheva I, et al. Magnetic nanogold microspheres-based lateral-flow immunodipstick for rapid detection of aflatoxin B2 in food. Biosens Bioelectron. 2009;25(2):514–8.CrossRef
90.
Fu Q, Liu HL, Wu Z, Liu A, Yao C, Li X, et al. Rough surface Au@ Ag core–shell nanoparticles to fabricating high sensitivity SERS immunochromatographic sensors. J Nanobiotech. 2015;13(1):81.CrossRef
91.
Blažková M, Rauch P, Fukal L. Strip-based immunoassay for rapid detection of thiabendazole. Biosens Bioelectron. 2010;25(9):2122–8.CrossRef
92.
Linares EM, Kubota LT, Michaelis J, Thalhammer S. Enhancement of the detection limit for lateral flow immunoassays: evaluation and comparison of bioconjugates. J Immunol Methods. 2012;375(1–2):264–70.CrossRef
93.
Suarez-Pantaleon C, Wichers J, Abad-Somovilla A, van Amerongen A, Abad-Fuentes A. Development of an immunochromatographic assay based on carbon nanoparticles for the determination of the phytoregulator forchlorfenuron. Biosens Bioelectron. 2013;42:170–6.CrossRef
94.
Huang Y-M, Dao-Feng L, Wei-Hua L, Xiong Y-H, Wan-Chun Y, Kun L, et al. Rapid detection of aflatoxin M1 by immunochromatography combined with enrichment based on immunomagnetic nanobead. Chin J Anal Chem. 2014;42(5):654–9.CrossRef
95.
Wang Y, Xu H, Wei M, Gu H, Xu Q, Zhu W. Study of superparamagnetic nanoparticles as labels in the quantitative lateral flow immunoassay. Mater Sci Eng C. 2009;29(3):714–8.CrossRef
96.
Liu C, Jia Q, Yang C, Qiao R, Jing L, Wang L, et al. Lateral flow immunochromatographic assay for sensitive pesticide detection by using Fe3O4 nanoparticle aggregates as color reagents. Anal Chem. 2011;83(17):6778–84.CrossRef
97.
Yan J, Liu Y, Wang Y, Xu X, Lu Y, Pan Y, et al. Effect of physiochemical property of Fe3O4 particle on magnetic lateral flow immunochromatographic assay. Sens Actuators B Chem. 2014;197:129–36.CrossRef
98.
Tang Y, Li Z, He N, Zhang L, Ma C, Li X, et al. Preparation of functional magnetic nanoparticles mediated with PEG-4000 and application in Pseudomonas aeruginosa rapid detection. J Biomed Nanotechnol. 2013;9(2):312–7.CrossRef
99.
Xu X, Deng C, Gao M, Yu W, Yang P, Zhang X. Synthesis of magnetic microspheres with immobilized metal ions for enrichment and direct determination of phosphopeptides by matrix-assisted laser desorption ionization mass spectrometry. Adv Mater. 2006;18(24):3289–93.CrossRef
100.
Qin Z, Chan WC, Boulware DR, Akkin T, Butler EK, Bischof JC. Significantly improved analytical sensitivity of lateral flow immunoassays by using thermal contrast. Angew Chem Int Ed. 2012;51(18):4358–61.CrossRef
101.
Wang Y, Qin Z, Boulware DR, Pritt BS, Sloan LM, Gonzalez IJ, et al. Thermal contrast amplification reader yielding 8-fold analytical improvement for disease detection with lateral flow assays. Anal Chem. 2016;88(23):11774–82.CrossRef
102.
Shen S, Henry A, Tong J, Zheng R, Chen G. Polyethylene nanofibres with very high thermal conductivities. Nat Nanotech. 2010;5(4):251.CrossRef
103.
Govorov AO, Richardson HH. Generating heat with metal nanoparticles. Nano Today. 2007;2(1):30–8.CrossRef
104.
Cate DM, Adkins JA, Mettakoonpitak J, Henry CS. Recent developments in paper-based microfluidic devices. Anal Chem. 2015;87(1):19–41.CrossRef
105.
Luo S, Xiao H, Yang S, Liu C, Liang J, Tang Y. Ultrasensitive detection of pentachlorophenol based on enhanced electrochemiluminescence of Au nanoclusters/graphene hybrids. Sens Actuators B Chem. 2014;194:325–31.CrossRef
106.
Xu Y, Lou B, Lv Z, Zhou Z, Zhang L, Wang E. Paper based solid-state electrochemiluminescence sensor using poly (sodium 4-styrenesulfonate) functionalized graphene/nafion composite film. Anal Chim Acta. 2013;763:20–7.CrossRef
107.
Li Z, Liu H, Ouyang C, Hong Wee W, Cui X, Jian Lu T, et al. Recent advances in pen-based writing electronics and their emerging applications. Adv Funct Mater. 2016;26(2):165–80.CrossRef
108.
Li Z, Li F, Hu J, Wee WH, Han YL, Pingguan-Murphy B, et al. Direct writing electrodes using a ball pen for paper-based point-of-care testing. Analyst. 2015;140(16):5526–35.CrossRef
109.
Siegel AC, Phillips ST, Wiley BJ, Whitesides GM. Thin, lightweight, foldable thermochromic displays on paper. Lab Chip. 2009;9(19):2775–81.CrossRef
110.
Matsuda Y, Shibayama S, Uete K, Yamaguchi H, Niimi T. Electric conductive pattern element fabricated using commercial inkjet printer for paper-based analytical devices. Anal Chem. 2015;87(11):5762–5.CrossRef
111.
Li Z, Hu J, Xu F, Li F. Recent developments of three-dimensional paper-based electrochemical devices for cancer cell detection and anticancer drug screening. Curr Pharm Biotechnol. 2016;17(9):802–9.CrossRef
112.
Wang P, Ge L, Yan M, Song X, Ge S, Yu J. Paper-based three-dimensional electrochemical immunodevice based on multi-walled carbon nanotubes functionalized paper for sensitive point-of-care testing. Biosens Bioelectron. 2012;32(1):238–43.CrossRef
113.
Ge L, Yan J, Song X, Yan M, Ge S, Yu J. Three-dimensional paper-based electrochemiluminescence immunodevice for multiplexed measurement of biomarkers and point-of-care testing. Biomaterials. 2012;33(4):1024–31.CrossRef
114.
Li W, Li L, Li M, Yu J, Ge S, Yan M, et al. Development of a 3D origami multiplex electrochemical immunodevice using a nanoporous silver-paper electrode and metal ion functionalized nanoporous gold–chitosan. Chem Commun. 2013;49(83):9540–2.CrossRef
115.
Ma C, Li W, Kong Q, Yang H, Bian Z, Song X, et al. 3D origami electrochemical immunodevice for sensitive point-of-care testing based on dual-signal amplification strategy. Biosens Bioelectron. 2015;63:7–13.CrossRef
116.
Wang DB, Tian B, Zhang ZP, Wang XY, Fleming J, Bi LJ, et al. Detection of Bacillus anthracis spores by super-paramagnetic lateral-flow immunoassays based on “Road Closure”. Biosens Bioelectron. 2015;67:608–14.CrossRef
117.
Ge L, Wang S, Song X, Ge S, Yu J. 3D origami-based multifunction-integrated immunodevice: low-cost and multiplexed sandwich chemiluminescence immunoassay on microfluidic paper-based analytical device. Lab Chip. 2012;12(17):3150–8.CrossRef
118.
Li W, Ge S, Wang S, Yan M, Ge L, Yu J. Highly sensitive chemiluminescence immunoassay on chitosan membrane modified paper platform using TiO2 nanoparticles/multiwalled carbon nanotubes as label. Luminescence. 2013;28(4):496–502.CrossRef
119.
Wang S, Ge L, Song X, Yan M, Ge S, Yu J, et al. Simple and covalent fabrication of a paper device and its application in sensitive chemiluminescence immunoassay. Analyst. 2012;137(16):3821–7.CrossRef
120.
Li L, Li W, Ma C, Yang H, Ge S, Yu J. Paper-based electrochemiluminescence immunodevice for carcinoembryonic antigen using nanoporous gold-chitosan hybrids and graphene quantum dots functionalized Au@Pt. Sens Actuators B Chem. 2014;202:314–22.CrossRef
121.
Li W, Li M, Ge S, Yan M, Huang J, Yu J. Battery-triggered ultrasensitive electrochemiluminescence detection on microfluidic paper-based immunodevice based on dual-signal amplification strategy. Anal Chim Acta. 2013;767:66–74.CrossRef
122.
Yan J, Ge L, Song X, Yan M, Ge S, Yu J. Paper-based electrochemiluminescent 3D immunodevice for lab-on-paper, specific, and sensitive point-of-care testing. Chem Eur J. 2012;18(16):4938–45.CrossRef
123.
Parolo C, Medina-Sanchez M, de la Escosura-Muniz A, Merkoci A. Simple paper architecture modifications lead to enhanced sensitivity in nanoparticle based lateral flow immunoassays. Lab Chip. 2013;13(3):386–90.CrossRef
124.
Shan S, Lai W, Xiong Y, Wei H, Xu H. Novel strategies to enhance lateral flow immunoassay sensitivity for detecting foodborne pathogens. J Agric Food Chem. 2015;63(3):745–53.CrossRef
125.
Qian S, Bau HH. A mathematical model of lateral flow bioreactions applied to sandwich assays. Anal Biochem. 2003;322(1):89–98.CrossRef
126.
Toley BJ, McKenzie B, Liang T, Buser JR, Yager P, Fu E. Tunable-delay shunts for paper microfluidic devices. Anal Chem. 2013;85(23):11545–52.CrossRef
127.
Liu Z, Hu J, Zhao Y, Qu Z, Xu F. Experimental and numerical studies on liquid wicking into filter papers for paper-based diagnostics. Appl Therm Eng. 2015;88:280–7.CrossRef
128.
Lutz B, Liang T, Fu E, Ramachandran S, Kauffman P, Yager P. Dissolvable fluidic time delays for programming multi-step assays in instrument-free paper diagnostics. Lab Chip. 2013;13(14):2840–7.CrossRef
129.
Whitesides GM. Viewpoint on “Dissolvable fluidic time delays for programming multi-step assays in instrument-free paper diagnostics”. Lab Chip. 2013;13(20):4004–5.CrossRef
130.
Li C, Boban M, Snyder SA, Kobaku SP, Kwon G, Mehta G, et al. Paper-based surfaces with extreme wettabilities for novel, open-channel microfluidic devices. Adv Funct Mater. 2016;26(33):6121–31.CrossRef
131.
Sun Y, Kharaghani A, Tsotsas E. Micro-model experiments and pore network simulations of liquid imbibition in porous media. Chem Eng Sci. 2016;150:41–53.CrossRef
132.
Jahanshahi-Anbuhi S, Henry A, Leung V, Sicard C, Pennings K, Pelton R, et al. Paper-based microfluidics with an erodible polymeric bridge giving controlled release and timed flow shutoff. Lab Chip. 2014;14(1):229–36.CrossRef
133.
Jahanshahi-Anbuhi S, Chavan P, Sicard C, Leung V, Hossain SM, Pelton R, et al. Creating fast flow channels in paper fluidic devices to control timing of sequential reactions. Lab Chip. 2012;12(23):5079–85.CrossRef
134.
Wang L, Cai J, Wang Y, Fang Q, Wang S, Cheng Q, et al. A bare-eye-based lateral flow immunoassay based on the use of gold nanoparticles for simultaneous detection of three pesticides. Microchim Acta. 2014;181(13–14):1565–72.CrossRef
135.
Lee J-H, Seo HS, Kwon J-H, Kim H-T, Kwon KC, Sim SJ, et al. Multiplex diagnosis of viral infectious diseases (AIDS, hepatitis C, and hepatitis A) based on point of care lateral flow assay using engineered proteinticles. Biosens Bioelectron. 2015;69:213–25.CrossRef
136.
Zhang D, Li P, Liu W, Zhao L, Zhang Q, Zhang W, et al. Development of a detector-free semiquantitative immunochromatographic assay with major aflatoxins as target analytes. Sens Actuators B Chem. 2013;185:432–7.CrossRef
137.
Zhang D, Li P, Zhang Q, Li R, Zhang W, Ding X, et al. A naked-eye based strategy for semiquantitative immunochromatographic assay. Anal Chim Acta. 2012;740:74–9.CrossRef
138.
Fang Q, Wang L, Cheng Q, Cai J, Wang Y, Yang M, et al. A bare-eye based one-step signal amplified semiquantitative immunochromatographic assay for the detection of imidacloprid in Chinese cabbage samples. Anal Chim Acta. 2015;881:82–9.CrossRef
139.
Oh YK, Joung HA, Han HS, Suk HJ, Kim MG. A three-line lateral flow assay strip for the measurement of C-reactive protein covering a broad physiological concentration range in human sera. Biosens Bioelectron. 2014;61:285–9.CrossRef
140.
Chen A, Wang R, Bever CR, Xing S, Hammock BD, Pan T. Smartphone-interfaced lab-on-a-chip devices for field-deployable enzyme-linked immunosorbent assay. Biomicrofluidics. 2014;8(6):064101.CrossRef
141.
Li B, Li L, Guan A, Dong Q, Ruan K, Hu R, et al. A smartphone controlled handheld microfluidic liquid handling system. Lab Chip. 2014;14(20):4085–92.CrossRef
142.
Vatsyayan P. Recent advances in the study of electrochemistry of redox proteins, Trends in Bioelectroanalysis bioanalytical reviews, vol. 6. Cham: Springer; 2016. p. 223–62.
143.
Zhang D, Liu Q. Biosensors and bioelectronics on smartphone for portable biochemical detection. Biosens Bioelectron. 2016;75:273–84.CrossRef
144.
Breslauer DN, Maamari RN, Switz NA, Lam WA, Fletcher DA. Mobile phone based clinical microscopy for global health applications. PLoS One. 2009;4(7):e6320.CrossRef
145.
Vashist SK, Mudanyali O, Schneider EM, Zengerle R, Ozcan A. Cellphone-based devices for bioanalytical sciences. Anal Bioanal Chem. 2014;406(14):3263–77.CrossRef
146.
Mudanyali O, Dimitrov S, Sikora U, Padmanabhan S, Navruz I, Ozcan A. Integrated rapid-diagnostic-test reader platform on a cellphone. Lab Chip. 2012;12(15):2678–86.CrossRef
147.
Pollock NR, Rolland JP, Kumar S, Beattie PD, Jain S, Noubary F, et al. A paper-based multiplexed transaminase test for low-cost, point-of-care liver function testing. Sci Transl Med. 2012;4(152):152ra29.CrossRef
148.
Thom NK, Yeung K, Pillion MB, Phillips ST. “Fluidic batteries” as low-cost sources of power in paper-based microfluidic devices. Lab Chip. 2012;12(10):1768–70.CrossRef
149.
Thom NK, Lewis GG, DiTucci MJ, Phillips ST. Two general designs for fluidic batteries in paper-based microfluidic devices that provide predictable and tunable sources of power for on-chip assays. RSC Adv. 2013;3(19):6888–95.CrossRef
150.
Liu H, Crooks RM. Paper-based electrochemical sensing platform with integral battery and electrochromic read-out. Anal Chem. 2012;84(5):2528–32.CrossRef
151.
Dineva MA, Candotti D, Fletcher-Brown F, Allain JP, Lee H. Simultaneous visual detection of multiple viral amplicons by dipstick assay. J Clin Microbiol. 2005;43(8):4015–21.CrossRef
152.
Vella SJ, Beattie P, Cademartiri R, Laromaine A, Martinez AW, Phillips ST, et al. Measuring markers of liver function using a micropatterned paper device designed for blood from a fingerstick. Anal Chem. 2012;84(6):2883–91.CrossRef
153.
Yang X, Forouzan O, Brown TP, Shevkoplyas SS. Integrated separation of blood plasma from whole blood for microfluidic paper-based analytical devices. Lab Chip. 2012;12(2):274–80.CrossRef
154.
Abe K, Kotera K, Suzuki K, Citterio D. Inkjet-printed paperfluidic immuno-chemical sensing device. Anal Bioanal Chem. 2010;398(2):885–93.CrossRef
155.
Li CZ, Vandenberg K, Prabhulkar S, Zhu X, Schneper L, Methee K, et al. Paper based point-of-care testing disc for multiplex whole cell bacteria analysis. Biosens Bioelectron. 2011;26(11):4342–8.CrossRef
156.
Vashist SK, Venkatesh AG, Mitsakakis K, Czilwik G, Roth G, von Stetten F, et al. Nanotechnology-based biosensors and diagnostics: technology push versus industrial/healthcare requirements. BioNanoSci. 2012;2(3):115–26.CrossRef
157.
Vashist SK, Schneider EM, Luong JHT. Commercial smartphone-based devices and smart applications for personalized healthcare monitoring and management. Diagnostics. 2014;4(3):104–28.CrossRef
Metadaten
Titel
Paper-Based Point-of-Care Immunoassays
verfasst von
Sandeep Kumar Vashist
Copyright-Jahr
2019
Buch
Point-of-Care Technologies Enabling Next-Generation Healthcare Monitoring and Management

Print ISBN: 978-3-030-11415-2

Electronic ISBN: 978-3-030-11416-9

Copyright-Jahr: 2019

DOI
https://doi.org/10.1007/978-3-030-11416-9_5

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