Anzeige
Erschienen in:
2015 | OriginalPaper | Buchkapitel
Polymer Capsules and Electroporation
verfasst von : Tatiana A. Kolesnikova, Raghavendra Palankar, Mathias Winterhalter
Erschienen in: 6th European Conference of the International Federation for Medical and Biological Engineering
Aktivieren Sie unsere intelligente Suche, um passende Fachinhalte oder Patente zu finden.
Wählen Sie Textabschnitte aus um mit Künstlicher Intelligenz passenden Patente zu finden. powered by
Markieren Sie Textabschnitte, um KI-gestützt weitere passende Inhalte zu finden. powered by
Intracellular delivery system may benefit from various types of cages ranging in diameter from 30 nm to several micrometers. Broad ranges of materials serve as building blocks for such compartments. Polymer capsules may provide a distinct chemical environment protecting the capsule interior from potentially hostile exterior environment. Bringing such functionalized compartments inside cells for detection, delivery sampling or retrieval of molecules is tempting. Electroporation is the method of choice for general intracellular delivery of small molecules, whereas for micrometer-sized capsules this is not obvious. Previously we have shown that electroporation promotes endocytosis bringing micrometer sized capsules into the endosome and allow for slow escape within a few hours.