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The 2012 International Conference on Applied Biotechnology (ICAB 2012) was held in Tianjin, China on October 18-19, 2012. It provides not only a platform for domestic and foreign researchers to exchange their ideas and experiences with the application-oriented research of biotechnology, but also an opportunity to promote the development and prosperity of the biotechnology industry. The proceedings of ICAB 2012 mainly focus on the world's latest scientific research and techniques in applied biotechnology, including Industrial Microbial Technology, Food Biotechnology, Pharmaceutical Biotechnology, Environmental Biotechnology, Marine Biotechnology, Agricultural Biotechnology, Biological Materials and Bio-energy Technology, Advances in Biotechnology, and Future Trends in Biotechnology. These proceedings are intended for scientists and researchers engaging in applied biotechnology. Professor Pingkai Ouyang is the President of the Nanjing University of Technology, China. Professor Tongcun Zhang is the Director of the Key Laboratory of Industrial Fermentation Microbiology of the Ministry of Education at the College of Bioengineering, Tianjin University of Science and Technology, China. Dr. Samuel Kaplan is a Professor at the Department of Microbiology & Molecular Genetics at the University of Texas at Houston Medical School, Houston, Texas, USA. Dr. Bill Skarnes is a Professor at Wellcome Trust Sanger Institute, United Kingdom.

Inhaltsverzeichnis

Frontmatter

Pharmaceutical Biotechnology

Frontmatter

2014 | OriginalPaper | Buchkapitel

Chapter 66. Promising Biomarkers: MicroRNAs at Diagnosis, Therapy and Prognostic Evaluation of Breast Cancer

Dalin Lu, Nan Wang, Xinghua Liao, Xuan Huang, Jianhua Zhang, Zhenyu Wang, Lian Duan, Jiajie Liu, Baoshu Jin, Yue Wang, Tong-Cun Zhang

2014 | OriginalPaper | Buchkapitel

Chapter 67. Dimerization of Chemokine Receptors and its Novel Roles in Drug Discovery

Mingqing Wang, Baosheng Ge, Fang Huang

2014 | OriginalPaper | Buchkapitel

Chapter 68. The Mechanism of Apoptosis in Adenocarcinoma of Lung Cancer A549 Cells Induced by Albumin-Derived from Peanut

Minhui Long, Yuejun Sun, Ni Chen, Zimin Zhang, Wen Chu, Yue Ma, Shenheng Luo, Zhongpeng Zhao, Aipo Diao

2014 | OriginalPaper | Buchkapitel

Chapter 69. Serum miR-124 and TNF-α are Biomarkers of Ischemic Cerebrovascular Disease

Jiajie Liu, Xinghua Liao, Nan Wang, Jun Zhou, Lian Duan, Dalin Lu, Zhipeng Liu, Tingbao Yan, Deyun Ma, Xiumei Dong, Xueguang Sun, Tong-Cun Zhang

2014 | OriginalPaper | Buchkapitel

Chapter 70. A New Process for Preparation of Hydroxytyrosol

Yinghao Gao, Xijuan Liang, Yuanmou Chen, Fei Hu, Weizhu Liu, Peng Yu, Erbing Hua

2014 | OriginalPaper | Buchkapitel

Chapter 71. Design and Synthesis of 2-Arylbenzimidazole Analogues as Novel SIRT1 Activators for the Treatment of Type II Diabetes

Fei Hu, Yuanmou Chen, Yinghao Gao, Shaolong Jia, Weizhu Liu, Peng Yu, Erbing Hua

2014 | OriginalPaper | Buchkapitel

Chapter 72. Design and Synthesis of SRT1 Activators for Potential Lead Compounds of Treatment of Diabetes

Weizhu Liu, Qiuyue Wang, Fei Hu, Yinghao Gao, Yingying Wang, Peng Yu, Erbing Hua

2014 | OriginalPaper | Buchkapitel

Chapter 73. Synthesis of 1,3-benzodioxol-5-ethanol and Its Derivatives

Na Ji, Yinghao Gao, Yuanmou Chen, Shaolong Jia, Fei Hu, Peng Yu, Erbing Hua

2014 | OriginalPaper | Buchkapitel

Chapter 74. Tetrandrine Inhibits Proteasomal Chymotrypsin-Like Activity and Induces Apoptosis in Human PC-3 Cells

Li Zhang, Wanxin Shi, Weihua Cao, Xiangru Liang, Yufu Hu, Mo Chen, Guoqing Shi

2014 | OriginalPaper | Buchkapitel

Chapter 75. The Purifying Effect of Apocynum Venetum Seedlings on Estuarine Water

Yangcang Xu, Tao Yu, Yunshan Zhong, Xiaoyan Wang

2014 | OriginalPaper | Buchkapitel

Chapter 76. Expression, Purification, and Activity Assay of Chicken Interferon-Alpha

Yue Ma, Minhui Long, Aipo Diao

2014 | OriginalPaper | Buchkapitel

Chapter 77. Synthesis and Controlled Release of 5-Fluorouracil from Hydroxyethylchitosan: Based Polymer Prodrug

Yanfei Peng, Wanshun Liu, Baoqin Han, Ruixue Zhou

2014 | OriginalPaper | Buchkapitel

Chapter 78. Telomerase is Significant as an Early Diagnostic Marker and Therapeutic Target

Lian Duan, Nan Wang, Xinghua Liao, Jun Zhou, Dalin lu, Jiajie Liu, Xueguang Sun, Tong-Cun Zhang

2014 | OriginalPaper | Buchkapitel

Chapter 79. Isolation, Identification, Antibacterial Effects of Antibiotic Drugs, and Chinese Herbal Extracts to the Pathogenic Bacteria of Swollen Abdomen from Scophthalmus maximus in Vitro

Xuan Wu, Dongqing Bai, Guoxia Zhu, Yanbin Ji, Zhichao Jia, Peng Zhou

2014 | OriginalPaper | Buchkapitel

Chapter 80. Lichen: A Potential Anticancer Officinal Resource

Meirong Ren, Xinli Wei, Feng Xu

2014 | OriginalPaper | Buchkapitel

Chapter 81. Clinical Significance of Screening Impaired Glucose Tolerance in Essential Hypertension Patients

Jun Zhu, Peiqing Feng, Shu Guo, Xinghua Liao, Jiajie Liu, Junfang Zhang, Tingbao Yan, Yue Wang, Tong-Cun Zhang

2014 | OriginalPaper | Buchkapitel

Chapter 82. Cardiac Hypertrophy-Specific Genes are Synergistic Activated by Myocardin and CREB-binding protein (CBP) p300

Zhenyu Wang, Xuehua Zhao, Mingzhe Li, Dongsun Cao, Tong-Cun Zhang

2014 | OriginalPaper | Buchkapitel

Chapter 83. Design, Synthesis and Biological Evaluation of the Novel Antitumor Agent 2-benzyl-3, 4-dihydroisoquinolin-1(2H)-one and Its Derivatives

Jian Lv, Lei Lv, Xiaomin Zhang, Yao Zhou, Kui Lu, Yifei lu, Yuou Teng, Hua Sun, Peng Yu

2014 | OriginalPaper | Buchkapitel

Chapter 84. Using Water Miscible Ionic Liquid to Improve the Efficiency of 15α-hydroxylation of 13-ethyl-gon-4-en-3,17-dione by Penicillium raistrickii

Shuhong Mao, Na Wang, Zhijiang Ge, Boyuan Hua, Yanqing Li, Fuping Lu

2014 | OriginalPaper | Buchkapitel

Chapter 85. Nuclear Receptor Property of E2F1 for Novel Anticancer Drug Discovery

Ning Zhang, Jin Li, Aimin Meng

2014 | OriginalPaper | Buchkapitel

Chapter 86. MRTF-A Promotes Migration of MCF-7 Breast Cancer Cells via Transactivation of CYR61

Xuegang Luo, Chunling Zhang, Wenwen Zhao, Lei Liu, Shu Guo, Zhipeng Liu, Jing Wang, Tong-Cun Zhang

2014 | OriginalPaper | Buchkapitel

Chapter 87. The Analysis of the Inhibition Effect of Cholic Acid Derivatives on the Proliferation of Breast Cancer Cells

Xuegang Luo, Jing Wang, Xiangchao Gu, Chunling Zhang, Xiangzheng Hu, Tong-Cun Zhang

2014 | OriginalPaper | Buchkapitel

Chapter 88. Design, Synthesis and Biological Evaluation of the Novel Antitumor Agent 5-Bromobenzofuran-3(2H)-One and its Derivatives

Lei Lv, Xiaomin Zhang, Jian Lv, Yao Zhou, Weiguo Hu, Peng Yu, Hua Sun, Yuou Teng

2014 | OriginalPaper | Buchkapitel

Chapter 89. Preliminary Study on the Mechanism of Cartilage Polysaccharide Inducing H22 Cell to Engender Immunogenicity

Guoqiang Zheng, Pan Li, Anguo Teng, Jie Zheng, Wenhang Wang, Anjun Liu

2014 | OriginalPaper | Buchkapitel

Chapter 90. Design and Synthesis of Novel 20-Substituted Hydroxycamptothecin Derivatives

Shaopeng Wen, Dewu Quan, Yao Zhou, Haiyong Jia, Peng Yu, Hua Sun, Na Guo

2014 | OriginalPaper | Buchkapitel

Chapter 91. Design and Synthesis of 5-Azacytidine Analogs

Jianbo Xing, Hua Sun, Xijuan Liang, Yuou Teng, Peng Yu, Kui Lu

2014 | OriginalPaper | Buchkapitel

Chapter 92. Stigmasterol from the Flowers of Trollius chinensis

Mengmeng Zhou, Min Wang, Daoqing Xu, Qin Pan

2014 | OriginalPaper | Buchkapitel

Chapter 93. Design, Synthesis and Primary Biological Evaluation of the Novel Antitumor Agent Indoline-3-One and Its Derivatives

Haiyong Jia, Guojun Pan, Yiqian Wang, Shaopeng Wen, Qiannan Guo, Weiguo Hu, Peng Yu, Hua Sun, Yuou Teng

2014 | OriginalPaper | Buchkapitel

Chapter 94. Research Progress on the Anti-Rheumatoid Arthritis Drugs

Peng Wang, Xuegang Luo, Chongxi Wang, Xinjia Wang, Guang Hu, Tong-Cun Zhang

2014 | OriginalPaper | Buchkapitel

Chapter 95. Design and Synthesis of 1H-2, 3-Dihydro-1-Pyrrolizinones Derivatives

Changhai Sun, Jing Cao

2014 | OriginalPaper | Buchkapitel

Chapter 96. Inhibition of iNOS to Protect Intermittent Hypoxia-Induced Hippocampal Neurons Impairment by Astragalus Extract in Rat

Qiang Zhang, Wenyuan Gao, Shuli Man, Yun Zhang, Baoyuan Chen

2014 | OriginalPaper | Buchkapitel

Chapter 97. Prepared and Characterization of 12β, 15α-Dihydroxy- 16α,17-Epoxyprogesterone

Yibo Wang, Yanbing Shen, Jiajia Ren, Jianmei Luo, Min Wang

Agricultural, Environmental, Marin Biotechnology and Bio-energy Technology

Frontmatter

2014 | OriginalPaper | Buchkapitel

Chapter 98. Structure Elucidation of Two Triterpenoid Saponins from Leaves of Schima superba Gardn. et Champ

Guanghua Huo, Changling Zhang, Yingjun Zhang

2014 | OriginalPaper | Buchkapitel

Chapter 99. Study on Extraction of Xylan from Bamboo Shoot Shell

Nengfu Yu, Nengliang Wu, Yu Wang, Yegou Tu

2014 | OriginalPaper | Buchkapitel

Chapter 100. Study on Preparation of Low Alcoholic Wine from Tomato

Kai-ye Deng, Er-na Li

2014 | OriginalPaper | Buchkapitel

Chapter 101. Effects of Glucose Assimilation on Lutein and Chlorophyll Biosyntheses in the Green Alga Chlorella pyrenoidosa

Tao Li, Yi-han Liu, Fu-ping Lu, Yue Jiang

2014 | OriginalPaper | Buchkapitel

Chapter 102. RNA Interference and Applications in Plants

Yunrong An, Zhongyou Pei, Nan Xin, Haifeng Wang

2014 | OriginalPaper | Buchkapitel

Chapter 103. Isolation, Identification and Degradation Characteristics of Three Thick Oil Degrading Bacteria Strains

Chan Tian, Shengyan Tian, Xianbin Liu, Lulu Qin

2014 | OriginalPaper | Buchkapitel

Chapter 104. Effect of Anti-Nematode Preparations on Physiological Traits of Cucumber Leaves Affected by Root-Knot Nematode

Shuchang Lu

2014 | OriginalPaper | Buchkapitel

Chapter 105. Enzymolysis and Microbial Transformation of Geniposide in Gardenia Jasminoides into Genipin by Aspergillus niger

Yu Li, Wenbin Jin, Wei Jing, Mengcheng Yao, Yanyang Tang, Fuping Lu

2014 | OriginalPaper | Buchkapitel

Chapter 106. Study on the Application of a Thermotolerant Saccharomyces cerevisiae in the Production of Bioethanol

Yueqiang Li, Yefu Chen, Jian Dong, Xinxin Zhang, Tong Shen, Dongguang Xiao

2014 | OriginalPaper | Buchkapitel

Chapter 107. Different Chemicals Stimulate Diapause Termination of Artemia Embryos

Yuqing Chen, Bo Zhang

2014 | OriginalPaper | Buchkapitel

Chapter 108. Dominant Bacteria TCCC15005 Used for Treatment of Alkaline Wastewater from Oil Refinery in a SBR

Jing Yang, Hua Zhao, Xi Wang, Xin Feng, Xinhua Wang

2014 | OriginalPaper | Buchkapitel

Chapter 109. Isolation and Characterization of a New Moderately Halophilic Bacterium Strain SM. 200-5 from Solar Saltern Ponds

Gaochao Xu, Yuangao Deng, Donghui Song, Liying Sui

2014 | OriginalPaper | Buchkapitel

Chapter 110. Preparation of Wetting Powder for Biocontrol Bacillus Subtilis

Fang Chen, Shangjing Guo, Haiying Shi, Deduo Han, Yuanjun Kang, Yu Zheng, Min Wang

2014 | OriginalPaper | Buchkapitel

Chapter 111. Isolation and Characterization of s-Butanol Tolerant Microorganisms

Litao Shi, Hongjiang Yang, Qian Li, Xuying Qin

2014 | OriginalPaper | Buchkapitel

Chapter 112. Application of Support Vector Machine in Base Liquor Classification

Junsen Lu, Liping Du, Haimei Ding, Ziping Du, Dongguang Xiao

2014 | OriginalPaper | Buchkapitel

Chapter 113. Isolation and Characterization of n-Butanol Tolerant Microorganisms

Yue Yu, Hongjiang Yang, Qun Li, Xuying Qin

2014 | OriginalPaper | Buchkapitel

Chapter 114. Effects of Dual-Frequency Ultrasound with α-amylase on the Properties and Structure of Mung Bean Starch

Aijun Hu, Jing Lu, Jie Zheng, Xiaoqing Zhang, Ying Zhang, Tong-Cun Zhang, Qian Li, Lin Yang

2014 | OriginalPaper | Buchkapitel

Chapter 115. Relationship Between Diet and Stable Carbon and Nitrogen Isotope Composition in Beef Tissues

Fengmei Sun, Guangyu Shi, Huiwen Wang, Shuming Yang

2014 | OriginalPaper | Buchkapitel

Chapter 116. Expression and Sequence Analysis of ChRpS3, a Ribosomal Protein S3 cDNA, and its Potential Role in Ovary Development of Cymbidium hybridium

Xiaoqiang Chen, Xiulan Li, Ning Sun, Wenqin Song

2014 | OriginalPaper | Buchkapitel

Chapter 117. Lichen Flora on the Genera Alectoria, Pseudephebe, and Sulcaria (Lichenized Ascomycota, Parmeliaceae)from the Hengduan Mountains in China (4)

Xinyu Wang, Dong Liu, Jianwen Li, Hiroshi Harada, Lisong Wang

2014 | OriginalPaper | Buchkapitel

Chapter 118. Discussion on the New and the Old Country Mark in Detecting the Coliform Bacteria

Lin Huang, Chunxia Wang, Ying Zhang, Fan Mei, Yan Huang, Jinpeng Wang, Bo Zheng

2014 | OriginalPaper | Buchkapitel

Chapter 119. Screening Autotetraploid Plantlets of Glycyrrhiza uralnesis Fisch by Colchicine-Treated Bud Culture

Xinglin Li, Junting Lu, Xuefei Cao, Na Zhao, Yang Han, Aijia Cao, Jie Ding, Jun Zhao

2014 | OriginalPaper | Buchkapitel

Chapter 120. Screening of Antimicrobial Marine Microorganisms and Purifying of Its Bioactive Substances

Zhiwen Liu, Qiankun Ruan, Sirigulen Qian, Lina Cong

2014 | OriginalPaper | Buchkapitel

Chapter 121. Determination of Dichloromethane in Waste Water Using Headspace Gas Chromatography

Chaozheng Zhang, Huijing Xu, Yutao Li, Fuhai Wang

2014 | OriginalPaper | Buchkapitel

Chapter 122. Simulation of Bio-syngas Production from Biomass Gasification via Pressurized Interconnected Fluidized Beds

Fei Feng, Guohui Song, Laihong Shen, Jun Xiao

2014 | OriginalPaper | Buchkapitel

Chapter 123. Research on Salt-tolerant Gene GPD1 in Zygosaccharomyces rouxii

Lihua Hou, Yanfei Yu, Cong Wang, Chunling Wang

2014 | OriginalPaper | Buchkapitel

Chapter 124. Mutagenic Research on Ciliary Neurotrophic Factor (CNTF) in Escherichia coli After Heavy Ions Irradiation

Xiaodong Jin, Qingfeng Wu, Xinguo Liu, Yan Liu, Yong Chen, Jian Lu, Lin Jiang

2014 | OriginalPaper | Buchkapitel

Chapter 125. Molecular Characterization and Expression of Ribosomal Protein L15 Gene (RPL15) From Arachis hypogaea

Qi Wu, Xiuzhen Wang, Hongtao Yu, Yufei Ding, Fenggao Cui, Jiancheng Zhang, Yueyi Tang, Chuantang Wang

2014 | OriginalPaper | Buchkapitel

Chapter 126. Optimization of Extraction Conditions for Glycosaminoglycan from Urechis unicinctus by Response Surface Methodology

Chunying Yuan, Xu Han, Qingman Cui, Ping Liu

2014 | OriginalPaper | Buchkapitel

Chapter 127. Quantitative Trait Loci Mapping of Unstripped Germ Rate in Milled Rice

Shengbin Liu, Fang Wang, Zetian Hua, Meng Meng, Fei Zhao, Xin Liu

2014 | OriginalPaper | Buchkapitel

Chapter 128. The Application of the GSI in the Preservation and Quality Control of Oat Beverage

Yuzhu Liu, Min Zhang

2014 | OriginalPaper | Buchkapitel

Chapter 129. The Effect of Carbon Nanotubes on Rice Seed Germination and Root Growth

Yumei Jiang, Zetian Hua, Yiqing Zhao, Qindai Liu, Fang Wang, Qin Zhang

2014 | OriginalPaper | Buchkapitel

Chapter 130. Study on the Accumulation Laws of Protein in Japonica Rice Seed During Development

Fang Wang, Bolian Sun, Chunkai Gu, Jiajia Mi, Qin Zhang, Zetian Hua

2014 | OriginalPaper | Buchkapitel

Chapter 131. Prevalence Investigation of Tetracycline Resistant Bacteria in Raw Milk

Xiaomei Zhang, Hongjiang Yang

2014 | OriginalPaper | Buchkapitel

Chapter 132. Study on Biological Denitrification Removal Technologies Treating Eutrophication Water

Zongzheng Yang, Huan Zhang, Deqiang Zhang, Jinzhao Pang

2014 | OriginalPaper | Buchkapitel

Chapter 133. Study on Decolorization Effect of Biological Strengthening the Activated Carbon with White Rot Fungi

Zongzheng Yang, Junxia Xu, Peng Yu, Jinzhao Pang

2014 | OriginalPaper | Buchkapitel

Chapter 134. The Removal of Crude Oil in Waste Drilling Muds by a Constructed Microbial Consortium

Yunkang Chang, Xingbiao Wang, Yifan Han, Manman Wang, Chenggang Zheng, Yongli Wang, Zhiyong Huang

2014 | OriginalPaper | Buchkapitel

Chapter 135. Isolation and Identification of Saline Tolerance Phosphate-Solubilizing Bacteria Derived from Salt-affected Soils and Their Mechanisms of P-solubilizing

Yang Han, Chunmei Wang, Xinglin Li, Xuefei Cao, Aijia Cao, Na Zhao

2014 | OriginalPaper | Buchkapitel

Chapter 136. Isolation and Characterization of a Bacillus Strain for Alkaline Wastewater Treatment

Kun Chen, Wenyu Shi, Jing Yang, Tong-cun Zhang, Hua Zhao
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