nach oben

Journal of Materials Engineering and Performance

Erschienen in:

14.10.2020

Production and Characterization of a Bone-Like Porous Ti/Ti-Hydroxyapatite Functionally Graded Material

verfasst von: Eren Yılmaz, Feyza Kabataş, Azim Gökçe, Fehim Fındık

Erschienen in: Journal of Materials Engineering and Performance | Ausgabe 10/2020

Einloggen

Aktivieren Sie unsere intelligente Suche, um passende Fachinhalte oder Patente zu finden.

search-config

KI-gestützte Suche

Aus

Abstract

A new kind of functionally graded material (FGM) that mimics the inner porous structure and outer dense layer of human bone was produced using powder metallurgy. The inner part of the FGM material (16 mm in diameter) has porosity of approximately 60%, and its mechanical properties are compatible with cortical bone; however, the shell (1.8 mm in thickness) is composed of a layer of Ti-10% wt. hydroxyapatite (HA) and shows hydrophilic behavior and improved biofunction. Elastic moduli of the core and shell layer were calculated as 18.99 and 42.98 GPa, respectively, and those values are compatible with that of cortical bone. Addition of HA to the shell had a significant effect on the wettability (81.6% decrease) and cell viability (46% increase). Furthermore, the porosity of the shell layer (28.88%) is similar to that of human cortical bone. It is concluded that the developed Ti-HA FGM has promising properties for implant applications.

Vorheriger Artikel Formation and Elimination Mechanism of Lack of Fusion and Cracks in Direct Laser Deposition 24CrNiMoY Alloy Steel

Nächster Artikel Effect of Heat Treatment Process on Microstructure and Crystallography of 20CrMnTiH Spur Bevel Gear

Sie haben noch keine Lizenz? Dann Informieren Sie sich jetzt über unsere Produkte:

Springer Professional "Wirtschaft+Technik"

Online-Abonnement

Mit Springer Professional "Wirtschaft+Technik" erhalten Sie Zugriff auf:

über 102.000 Bücher
über 537 Zeitschriften

aus folgenden Fachgebieten:

Automobil + Motoren
Bauwesen + Immobilien
Business IT + Informatik
Elektrotechnik + Elektronik
Energie + Nachhaltigkeit
Finance + Banking
Management + Führung
Marketing + Vertrieb
Maschinenbau + Werkstoffe
Versicherung + Risiko

Jetzt Wissensvorsprung sichern!

Jetzt informieren

Springer Professional "Technik"

Online-Abonnement

Mit Springer Professional "Technik" erhalten Sie Zugriff auf:

über 67.000 Bücher
über 390 Zeitschriften

aus folgenden Fachgebieten:

Automobil + Motoren
Bauwesen + Immobilien
Business IT + Informatik
Elektrotechnik + Elektronik
Energie + Nachhaltigkeit
Maschinenbau + Werkstoffe

Jetzt Wissensvorsprung sichern!

Jetzt informieren

B. Zhang, D. Myers, G. Wallace, M. Brandt, and P. Choong, Bioactive Coatings for Orthopaedic Implants—Recent Trends in Development of Implant Coatings, Int. J. Mol. Sci., 2014, 15(7), p 11878–11921. https://doi.org/10.3390/ijms150711878CrossRef

M. Geetha, A.K. Singh, R. Asokamani, and A.K. Gogia, Ti Based Biomaterials, the Ultimate Choice for Orthopaedic Implants—A Review, Prog. Mater Sci., 2009, 54(3), p 397–425. https://doi.org/10.1016/j.pmatsci.2008.06.004CrossRef

E. Yilmaz, A. Gökçe, F. Findik, and H.Ö. Gülsoy, Powder Metallurgy Processing of Ti-Nb Based Biomedical Alloys, Acta Phys. Pol., A, 2018, 134(1), p 278–280. https://doi.org/10.12693/APhysPolA.134.278CrossRef

E. Yılmaz, A. Gökçe, F. Findik, and H.Ö. Gülsoy, Characterization of Biomedical Ti-16Nb-(0–4)Sn Alloys Produced by Powder Injection Molding, Vacuum, 2017, 142, p 164–174. https://doi.org/10.1016/j.vacuum.2017.05.018CrossRef

E. Yılmaz, B. Çakıroğlu, A. Gökçe, F. Findik, H.O. Gulsoy, N. Gulsoy, Ö. Mutlu, and M. Özacar, Novel Hydroxyapatite/Graphene Oxide/Collagen Bioactive Composite Coating on Ti16Nb Alloys by Electrodeposition, Mater. Sci. Eng., C, 2019, 101, p 292–305. https://doi.org/10.1016/j.msec.2019.03.078CrossRef

E. Yılmaz, A. Gökçe, F. Findik, and H.Ö. Gulsoy, Metallurgical Properties and Biomimetic HA Deposition Performance of Ti-Nb PIM Alloys, J. Alloys Compd., 2018, 746, p 301–313. https://doi.org/10.1016/j.jallcom.2018.02.274CrossRef

S. Sazesh, A. Ghassemi, R. Ebrahimi, and M. Khodaei, Fabrication and Characterization of NHA/Titanium Dental Implant, Mater. Res. Express, 2019, 6(4), p 045060. https://doi.org/10.1088/2053-1591/aafddcCrossRef

S. Anil, P.S. Anand, H. Alghamdi, and J.A. Janse, Dental Implant Surface Enhancement and Osseointegration, Implant Dentistry - A Rapidly Evolving Practice, I. Turkyilmaz, Ed., (Rijeka), InTech, 2011, https://doi.org/10.5772/16475.

A. Arifin, A.B. Sulong, N. Muhamad, J. Syarif, and M.I. Ramli, Material Processing of Hydroxyapatite and Titanium Alloy (HA/Ti) Composite as Implant Materials Using Powder Metallurgy: A Review, Mater. Des., 2014, 55, p 165–175. https://doi.org/10.1016/j.matdes.2013.09.045CrossRef

10.

A. Jarrahi, H.A. Shirazi, A. Asnafi, and M.R. Ayatollahi, Biomechanical Analysis of a Radial Functionally Graded Dental Implant-Bone System under Multi-Directional Dynamic Loads, J. Brazilian Soc. Mech. Sci. Eng., 2018, 40(5), p 249. https://doi.org/10.1007/s40430-018-1166-9CrossRef

11.

M. Mehrali, F.S. Shirazi, M. Mehrali, H.S.C. Metselaar, N.A. Bin Kadri, and N.A.A. Osman, Dental Implants from Functionally Graded Materials, J. Biomed. Mater. Res., Part A, 2013, 101(10), p 3046–3057. https://doi.org/10.1002/jbm.a.34588CrossRef

12.

M. Sedighi, N. Omidi, and A. Jabbari, Experimental Investigation of FGM Dental Implant Properties Made from Ti/HA Composite, Mech. Adv. Compos. Struct., 2017, 4(3), p 233–237. https://doi.org/10.22075/macs.2017.1819.1096CrossRef

13.

M. Roy, V.K. Balla, A. Bandyopadhyay, and S. Bose, Compositionally Graded Hydroxyapatite/Tricalcium Phosphate Coating on Ti by Laser and Induction Plasma, Acta Biomater., 2011, 7(2), p 866–873. https://doi.org/10.1016/j.actbio.2010.09.016CrossRef

14.

H.-D. Jung, H. Lee, H.-E. Kim, Y.-H. Koh, and J. Song, Fabrication of Mechanically Tunable and Bioactive Metal Scaffolds for Biomedical Applications, J. Vis. Exp., 2015, https://doi.org/10.3791/53279CrossRef

15.

H. Lee, T.-S. Jang, J. Song, H.-E. Kim, and H.-D. Jung, The Production of Porous Hydroxyapatite Scaffolds with Graded Porosity by Sequential Freeze-Casting, Materials, 2017, 10(4), p 367. https://doi.org/10.3390/ma10040367CrossRef

16.

Y.H. He, Y.Q. Zhang, Y.H. Jiang, and R. Zhou, Effect of HA (Hydroxyapatite) Content on the Microstructure, Mechanical and Corrosion Properties of (Ti13Nb13Zr)-XHA Biocomposites Synthesized by Sparkle Plasma Sintering, Vacuum, 2016, 131, p 176–180. https://doi.org/10.1016/j.vacuum.2016.06.015CrossRef

17.

C. Han, Y. Li, Q. Wang, D. Cai, Q. Wei, L. Yang, S. Wen, J. Liu, and Y. Shi, Titanium/Hydroxyapatite (Ti/HA) Gradient Materials with Quasi-Continuous Ratios Fabricated by SLM: Material Interface and Fracture Toughness, Mater. Des., 2018, 141, p 256–266. https://doi.org/10.1016/j.matdes.2017.12.037CrossRef

18.

E. Yılmaz, A. Gökçe, F. Findik, H.O. Gulsoy, and O. İyibilgin, Mechanical Properties and Electrochemical Behavior of Porous Ti-Nb Biomaterials, J. Mech. Behav. Biomed. Mater., 2018, 87, p 59–67. https://doi.org/10.1016/j.jmbbm.2018.07.018CrossRef

19.

E. Yılmaz, A. Gökçe, F. Findik, and H.Ö. Gülsoy, Biomedical Porous Ti-16Nb-10Zr-(0–15)Ta Alloys, Int. J. Mater. Res., 2019, 110(4), p 375–378. https://doi.org/10.3139/146.111749CrossRef

20.

P. Balbinotti, E. Gemelli, G. Buerger, S.A. de Lima, J. de Jesus, N.H.A. Camargo, V.A.R. Henriques, and G.D.A. de Soares, Microstructure Development on Sintered Ti/HA Biocomposites Produced by Powder Metallurgy, Mater. Res., 2011, 14(3), p 384–393. https://doi.org/10.1590/s1516-14392011005000044CrossRef

21.

T. Kokubo and S. Yamaguchi, Novel Bioactive Materials Developed by Simulated Body Fluid Evaluation: Surface-Modified Ti Metal and Its Alloys, Acta Biomater., 2016, 44, p 16–30. https://doi.org/10.1016/j.actbio.2016.08.013CrossRef

22.

N. Omidi, A.H. Jabbari, and M. Sedighi, Mechanical and Microstructural Properties of Titanium/Hydroxyapatite Functionally Graded Material Fabricated by Spark Plasma Sintering, Powder Metall., 2018, 61(5), p 417–427. https://doi.org/10.1080/00325899.2018.1535391CrossRef

23.

M. Kutz, Bone Mechanics, Standard Handbook of Biomedical Engineering and Design, McGraw-Hill Professional, 2003

24.

B. Dabrowski, W. Swieszkowski, D. Godlinski, and K.J. Kurzydlowski, Highly Porous Titanium Scaffolds for Orthopaedic Applications, J. Biomed. Mater. Res. Part B Appl. Biomater., 2010, 95(1), p 53–61CrossRef

25.

S.P. Victor, M.G. Gayathri Devi, W. Paul, V.M. Vijayan, J. Muthu, and C.P. Sharma, Europium Doped Calcium Deficient Hydroxyapatite as Theranostic Nanoplatforms: Effect of Structure and Aspect Ratio, ACS Biomater. Sci. Eng., 2017, 3(12), p 3588–3595. https://doi.org/10.1021/acsbiomaterials.7b00453CrossRef

26.

L. Zhang, Z.Y. He, Y.Q. Zhang, Y.H. Jiang, and R. Zhou, Rapidly Sintering of Interconnected Porous Ti-HA Biocomposite with High Strength and Enhanced Bioactivity, Mater. Sci. Eng., C, 2016, 67, p 104–114. https://doi.org/10.1016/j.msec.2016.05.001CrossRef

27.

H. Ye, X.Y. Liu, and H. Hong, Characterization of Sintered Titanium/Hydroxyapatite Biocomposite Using FTIR Spectroscopy, J. Mater. Sci. Mater. Med., 2009, 20(4), p 843–850. https://doi.org/10.1007/s10856-008-3647-3CrossRef

28.

G. Alexandru Mihai, Ed., “Nanobiomaterials in Hard Tissue Engineering. Elsevier, 2016, https://doi.org/10.1016/c2015-0-00379-3.

29.

D. Smolen, T. Chudoba, I. Malka, A. Kedzierska, W. Lojkowski, W. Swieszkowski, K.J. Kurzydlowski, M. Kolodziejczyk-Mierzynska, and M. Lewandowska-Szumiel, Highly Biocompatible, Nanocrystalline Hydroxyapatite Synthesized in a Solvothermal Process Driven by High Energy Density Microwave Radiation, Int. J. Nanomed., 2013, https://doi.org/10.2147/ijn.s39299CrossRef

30.

Y. Yang, K.-H. Kim, C.M. Agrawal, and J.L. Ong, Interaction of Hydroxyapatite-Titanium at Elevated Temperature in Vacuum Environment, Biomaterials, 2004, 25(15), p 2927–2932. https://doi.org/10.1016/j.biomaterials.2003.09.072CrossRef

31.

G. Kahraman, Production and Characterization of Titanium - Hydroxyapatite Composites by Powder Metallurgy Method, Sakarya University of Applied Sciences, 2019, https://doi.org/https://tez.yok.gov.tr/UlusalTezMerkezi/TezGoster?key=npGs9H39x7G6401x51yqpADG0EGr6w0hqX5lDog8h19sXJGb7Ymx1rmbhYctHgwy.

32.

G. Kahraman, E. Yılmaz, and F. Fındık, Characterization of Ti-HA Biocomposite Produced by Powder Metallurgy, in 4th International conference on Materials Science and Technology, (Ankara), 2019, p 532–535.

33.

Y. Shu, G. Ou, L. Wang, J. Zou, and Q. Li, Surface Modification of Titanium with Heparin-Chitosan Multilayers via Layer-by-Layer Self-Assembly Technique, J. Nanomater., 2011, 2011, p 1–8. https://doi.org/10.1155/2011/423686CrossRef

34.

A. Kumar, K. Biswas, and B. Basu, On the Toughness Enhancement in Hydroxyapatite-Based Composites, Acta Mater., 2013, 61(14), p 5198–5215. https://doi.org/10.1016/j.actamat.2013.05.013CrossRef

35.

A.T. Sidambe, Biocompatibility of Advanced Manufactured Titanium Implants-A Review, Materials, 2014, 7(12), p 8168–8188. https://doi.org/10.3390/ma7128168CrossRef

36.

E. Yılmaz, A. Gökçe, F. Findik, and H.Ö. Gulsoy, Assessment of Ti–16Nb–XZr Alloys Produced via PIM for Implant Applications, J. Thermal Anal. Calorim., 2017, 134, p 1–8. https://doi.org/10.1007/s10973-017-6808-0CrossRef

37.

L. Zhang, Z.Y. He, Y.Q. Zhang, Y.H. Jiang, and R. Zhou, Enhanced in Vitro Bioactivity of Porous NiTi–HA Composites with Interconnected Pore Characteristics Prepared by Spark Plasma Sintering, Mater. Des., 2016, 101, p 170–180. https://doi.org/10.1016/j.matdes.2016.03.128CrossRef

38.

Y.L. Gao, Y. Liu, and X.Y. Song, Plasma-Sprayed Hydroxyapatite Coating for Improved Corrosion Resistance and Bioactivity of Magnesium Alloy, J. Therm. Spray Technol., 2018, 27(8), p 1381–1387. https://doi.org/10.1007/s11666-018-0760-9CrossRef

39.

U. Anjaneyulu, B. Priyadarshini, S. Arul Xavier Stango, M. Chellappa, M. Geetha, and U. Vijayalakshmi, Preparation and Characterisation of Sol–Gel-Derived Hydroxyapatite Nanoparticles and Its Coatings on Medical Grade Ti-6Al-4V Alloy for Biomedical Applications, Mater. Technol., 2017, 32(13), p 800–814. https://doi.org/10.1080/10667857.2017.1364476CrossRef

40.

C.M. Cotrut, A. Vladescu, M. Dinu, and D.M. Vranceanu, Influence of Deposition Temperature on the Properties of Hydroxyapatite Obtained by Electrochemical Assisted Deposition, Ceram. Int., 2018, 44(1), p 669–677. https://doi.org/10.1016/j.ceramint.2017.09.227CrossRef

41.

C.J. Wilson, R.E. Clegg, D.I. Leavesley, and M.J. Pearcy, Mediation of Biomaterial-Cell Interactions by Adsorbed Proteins: A Review, Tissue Eng., 2005, 11(1-2), p 1–18. https://doi.org/10.1089/ten.2005.11.1CrossRef

42.

J.K. Odusote, Y. Danyuo, A.D. Baruwa, and A.A. Azeez, Synthesis and Characterization of Hydroxyapatite from Bovine Bone for Production of Dental Implants, J. Appl. Biomater. Funct. Mater., 2019, 17(2), p 228080001983682. https://doi.org/10.1177/2280800019836829CrossRef

43.

Anawati, H. Tanigawa, H. Asoh, T. Ohno, M. Kubota, and S. Ono, Electrochemical Corrosion and Bioactivity of Titanium-Hydroxyapatite Composites Prepared by Spark Plasma Sintering, Corros. Sci., 2013, 70, p 212–220. https://doi.org/10.1016/j.corsci.2013.01.032CrossRef

44.

B. Alberts, A. Johnson, J. Lewis, M. Raff, K. Roberts, and P. Walter, Molecular Biology of the Cell, (New York), Garland Science, 2002, https://www.ncbi.nlm.nih.gov/books/NBK21054/.

45.

C. Jeon, K.C. Oh, K.-H. Park, and H.S. Moon, Effects of Ultraviolet Treatment and Alendronate Immersion on Osteoblast-like Cells and Human Gingival Fibroblasts Cultured on Titanium Surfaces, Sci. Rep., 2019, 9(1), p 2581. https://doi.org/10.1038/s41598-019-39355-3CrossRef

46.

J. Suwanprateeb, W. Suvannapruk, W. Chokevivat, S. Kiertkrittikhoon, N. Jaruwangsanti, and P. Tienboon, Bioactivity of a Sol–Gel-Derived Hydroxyapatite Coating on Titanium Implants in Vitro and in Vivo, Asian Biomed., 2018, 12(1), p 35–44. https://doi.org/10.1515/abm-2018-0029CrossRef

47.

A. Rutkovskiy, K.-O. Stensløkken, and I.J. Vaage, Osteoblast Differentiation at a Glance, Med. Sci. Monit. Basic Res., 2016, 22, p 95–106. https://doi.org/10.12659/MSMBR.901142CrossRef

48.

S. Dey, M. Das, and V.K. Balla, Effect of Hydroxyapatite Particle Size, Morphology and Crystallinity on Proliferation of Colon Cancer HCT116 Cells, Mater. Sci. Eng., C, 2014, 39, p 336–339. https://doi.org/10.1016/j.msec.2014.03.022CrossRef

49.

Y. Parcharoen, P. Termsuksawad, and S. Sirivisoot, Improved Bonding Strength of Hydroxyapatite on Titanium Dioxide Nanotube Arrays Following Alkaline Pretreatment for Orthopedic Implants, J. Nanomater., 2016, 2016, p 1–13. https://doi.org/10.1155/2016/9143969CrossRef

50.

G.M. Peñarrieta-Juanito, M. Costa, M. Cruz, G. Miranda, B. Henriques, J. Marques, R. Magini, A. Mata, J. Caramês, F. Silva, and J.C.M. Souza, Bioactivity of Novel Functionally Structured Titanium-Ceramic Composites in Contact with Human Osteoblasts, J. Biomed. Mater. Res., Part A, 2018, 106(7), p 1923–1931. https://doi.org/10.1002/jbm.a.36394CrossRef

51.

Y. Zeng, X. Pei, S. Yang, H. Qin, H. Cai, S. Hu, L. Sui, Q. Wan, and J. Wang, Graphene Oxide/Hydroxyapatite Composite Coatings Fabricated by Electrochemical Deposition, Surf. Coatings Technol., 2016, 286, p 72–79. https://doi.org/10.1016/j.surfcoat.2015.12.013CrossRef

Titel: Production and Characterization of a Bone-Like Porous Ti/Ti-Hydroxyapatite Functionally Graded Material
verfasst von: Eren Yılmaz
Feyza Kabataş
Azim Gökçe
Fehim Fındık
Publikationsdatum: 14.10.2020
Verlag: Springer US
Erschienen in: Journal of Materials Engineering and Performance / Ausgabe 10/2020
Print ISSN: 1059-9495
Elektronische ISSN: 1544-1024
DOI: https://doi.org/10.1007/s11665-020-05165-2

Premium Partner

Marktübersichten

Die im Laufe eines Jahres in der „adhäsion“ veröffentlichten Marktübersichten helfen Anwendern verschiedenster Branchen, sich einen gezielten Überblick über Lieferantenangebote zu verschaffen.

Zur Marktübersicht

Springer Professional

Abstract

Bitte loggen Sie sich ein, um Zugang zu Ihrer Lizenz zu erhalten.

Sie haben noch keine Lizenz? Dann Informieren Sie sich jetzt über unsere Produkte:

Springer Professional "Wirtschaft+Technik"

Springer Professional "Technik"

Weitere Artikel der Ausgabe 10/2020

Effects of Pre-stretching and Aging Treatments on Microstructure, Mechanical Properties, and Corrosion Behavior of Spray-Formed Al-Li Alloy 2195

Formation and Elimination Mechanism of Lack of Fusion and Cracks in Direct Laser Deposition 24CrNiMoY Alloy Steel

Microstructural Analysis of Cavity Formed in Advanced High-Strength Steel Resistance Spot Welds

Simulation of Neutron Irradiation Damage in Stainless Steel by Cold Rolling

Fatigue Performance and Strength Assessment of AA2024 Alloy Friction Stir Lap Welds

Thermophysical-Based Modeling of Material Removal in Powder Mixed Near-Dry Electric Discharge Machining

Premium Partner

Marktübersichten