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28.04.2020 | Original Research

Production and characterization of chitosan-TPP/cellulose nanocrystal system for encapsulation: a case study using folic acid as active compound

verfasst von: Nadia Obrownick Okamoto-Schalch, Sabrina Guarda Botelho Pinho, Taís Teo de Barros-Alexandrino, Gustavo César Dacanal, Odílio Benedito Garrido Assis, Milena Martelli-Tosi

Erschienen in: Cellulose | Ausgabe 10/2020

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Abstract

The aim of the present study was to propose a new approach on the preparation of a hybrid system composed of chitosan nanoparticles (ChNps) and cellulose nanocrystals (CNCs), as carriers of folic acid (FA). ChNp was prepared by ionic gelation technique using sodium tripolyphosphate (TPP) as crosslinker and CNCs from soybean pods, extracted by chemical pre-treatments and acid hydrolysis. The microscopic observation revealed clusters of fibers amongst the ChNps, arranged in a three-dimensional network as large as 1 to 3 µm in diameter. Zeta potential measurements of the particle suspensions loaded with FA did not differ significantly from those read for empty ChNps (both samples with values around + 23 to + 25 mV). The CNC hybrid system presented higher efficiency of encapsulation (72 ± 8%), compared to cross-linked ChNp system which has no fibers added (62 ± 4%). Moreover, the FA releasing (at pH 3.0 and 7.4) and the protection against light degradation were higher in the hybrid systems. Infrared spectroscopic and thermogravimetric analysis showed a better maintenance of the main vitamin structure when encapsulated by the composite particles.

Vorheriger Artikel Oil release behavior and kinetics of oil-impregnated kapok fiber powder

Nächster Artikel Palmitic acid functionalization of cellulose fibers for enhancing hydrophobic property

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Titel: Production and characterization of chitosan-TPP/cellulose nanocrystal system for encapsulation: a case study using folic acid as active compound
verfasst von: Nadia Obrownick Okamoto-Schalch
Sabrina Guarda Botelho Pinho
Taís Teo de Barros-Alexandrino
Gustavo César Dacanal
Odílio Benedito Garrido Assis
Milena Martelli-Tosi
Publikationsdatum: 28.04.2020
Verlag: Springer Netherlands
Erschienen in: Cellulose / Ausgabe 10/2020
Print ISSN: 0969-0239
Elektronische ISSN: 1572-882X
DOI: https://doi.org/10.1007/s10570-020-03173-y

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