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CC BY-NC-ND 4.0 · Indian J Radiol Imaging 2012; 22(04): 254-256
DOI: 10.4103/0971-3026.111472
ORIGINAL ARTICLE

Selective doxorubicin drug eluting beads chemoembolization of hypovascular hepatocellular carcinoma using cone beam computed tomography

Naveen Kalra
Department of Radiodiagnosis, Post-graduate Institute of Medical Education and Research, Chandigarh
,
Divyesh Mahajan
Department of Radiodiagnosis, Post-graduate Institute of Medical Education and Research, Chandigarh
,
Yogesh Chawla
Department of Hepatology, Post-graduate Institute of Medical Education and Research, Chandigarh
,
N Khandelwal
Department of Radiodiagnosis, Post-graduate Institute of Medical Education and Research, Chandigarh
› Author Affiliations Source of Support: Nill.
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Abstract

Hepatocellular carcinoma (HCC) of the liver is the third most common cause of cancer-related deaths in the world. Only one-third of patients with HCC are suitable candidates for hepatic resection. Transarterial chemoembolization (TACE) is performed in unresectable HCC. Drug-eluting beads (DEB) TACE is a modification of TACE, in which doxorubicin beads are used as embolizing material.These beads deliver the drug and embolize the vessels; however, it carries the risk of non-target embolization and it is difficult in cases with absent arterial blush on digital subtraction angiography (DSA). This is resolved using C-arm cone-beam computed tomography in the DSA suite. It identifies the tumor-feeding vessels, their area of supply, and differentiates between tumor and normal liver parenchyma. In addition, it is very useful in the embolization of hypovascular HCC. It helps and guides the radiologist in performing TACE effectively and also prevents non-target embolization of normal liver parenchyma.

Keywords

Cone-beam computed tomography - hepatocellular carcinoma - transarterial chemoembolization


Publication History

Article published online:
04 October 2021

© 2012. Indian Radiological Association. This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial-License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/).

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