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Numerical Modeling in the Design and Evaluation of Scaffolds for Orthopaedics Applications

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Computer-Aided Tissue Engineering

Part of the book series: Methods in Molecular Biology ((MIMB,volume 868))

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Abstract

Numerical modeling becomes a very useful tool for design and preclinical evaluation of scaffold for tissue engineering. This chapter illustrates, how finite element analysis and genetic algorithm maybe applied to predict the mechanical performance of novel scaffolds, with a honeycomb-like pattern, a fully interconnected channel network, and controllable porosity fabricated in layers of directionally aligned microfibers deposited using a computer-controlled extrusion process.

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Acknowledgments

The work was partially supported by Polish Ministry of Science and A*STAR under the Polish–Singapore Collaboration. The authors would like to thank Marcin Heljak for his help with the FE simulations.

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Authors and Affiliations

  1. Division of Materials Design, Faculty of Materials Science and Engineering, Warsaw University of Technology, Warszawa, Poland

    Wojciech Swieszkowski

  2. Faculty of Materials Science and Engineering, Warsaw University of Technology, Warszawa, Poland

    Krzysztof J. Kurzydlowski

Authors
  1. Wojciech Swieszkowski
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  2. Krzysztof J. Kurzydlowski
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Corresponding author

Correspondence to Wojciech Swieszkowski .

Editor information

Editors and Affiliations

  1. , Department of Neurosurgery, Baylor College of Medicine, Holcombe Blvd. 2002, Houston, 77030, Texas, USA

    Michael A.K. Liebschner

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Swieszkowski, W., Kurzydlowski, K.J. (2012). Numerical Modeling in the Design and Evaluation of Scaffolds for Orthopaedics Applications. In: Liebschner, M. (eds) Computer-Aided Tissue Engineering. Methods in Molecular Biology, vol 868. Humana Press, Totowa, NJ. https://doi.org/10.1007/978-1-61779-764-4_11

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  • DOI: https://doi.org/10.1007/978-1-61779-764-4_11

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  • Publisher Name: Humana Press, Totowa, NJ

  • Print ISBN: 978-1-61779-763-7

  • Online ISBN: 978-1-61779-764-4

  • eBook Packages: Springer Protocols

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