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Erschienen in:
Test Models for Statistical Inference: Two-Dimensional Reaction Systems Displaying Limit Cycle Bifurcations and Bistability Kapitel lesen Erstes Kapitel lesen

2017 | OriginalPaper | Buchkapitel

Recent Mathematical Models of Axonal Transport

verfasst von : Chuan Xue, Gregory Jameson

Erschienen in: Stochastic Processes, Multiscale Modeling, and Numerical Methods for Computational Cellular Biology

Verlag: Springer International Publishing

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Abstract

An axon is a long thin projection of a neuron that allows for rapid electrochemical communications with other cells over long distances. Axonal transport refers to the stochastic, bidirectional movement of organelles and proteins along cytoskeletal polymers inside an axon, powered by molecular motor proteins. The movement from the cell body to the axon terminal is called anterograde transport and the movement in the opposite direction is called retrograde transport. Axonal transport is a vital process for the axon to survive and maintain its regular shape. Mathematical models have been developed to help understand how cargoes are transported inside an axon and how impairment of axonal transport affects cargo distribution. In this chapter, we review recent mathematical models of axonal transport and discuss open problems in this area.

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Nächstes Kapitel Stochastic Models for Evolving Cellular Populations of Mitochondria: Disease, Development, and Ageing
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Metadaten
Titel
Recent Mathematical Models of Axonal Transport
verfasst von
Chuan Xue
Gregory Jameson
Copyright-Jahr
2017
Buch
Stochastic Processes, Multiscale Modeling, and Numerical Methods for Computational Cellular Biology

Print ISBN: 978-3-319-62626-0

Electronic ISBN: 978-3-319-62627-7

Copyright-Jahr: 2017

DOI
https://doi.org/10.1007/978-3-319-62627-7_12