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2019 | OriginalPaper | Buchkapitel

9. Recent Technological Developments in MALDI-MSI Based Hair Analysis

verfasst von : Bryn Flinders, Tom Bassindale, Ron M. A. Heeren

Erschienen in: Emerging Technologies for the Analysis of Forensic Traces

Verlag: Springer International Publishing

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Abstract

Hair is a common piece of trace evidence found at a crime scene, however, often it is not possible to obtain DNA (due to the lack of a follicular root). These hair samples could potentially provide other intelligence, based on the molecular history of an individual that it contains. Currently, this type of analysis is performed using traditional hyphenated techniques gas chromatography-mass spectrometry (GC-MS) or liquid chromatography-mass spectrometry (LC-MS). However, these techniques require a large amount of hair, not a few single strands such as those typically found at a crime scene and also involve extensive sample preparation. Recently new technologies such as matrix-assisted laser desorption/ionization-mass spectrometry imaging (MALDI-MSI) have been used to monitor the distribution of drugs of abuse in single hair strands. Using this technology it is possible to reveal the distribution of compounds in the hair more accurately and in single strands as opposed to milligram quantities required by traditional hyphenated methods. The use of MALDI-MSI could provide law enforcement agencies with lifestyle information on an individual and help to narrow down the pool of suspects.

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Vorheriges Kapitel End User Commentary on Investigating the Age of Blood Traces: How Close Are We to Finding the Holy Grail of Forensic Science?

Nächstes Kapitel End User Commentary on Recent Technological Developments in MALDI-MSI Based Hair Analysis

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Titel: Recent Technological Developments in MALDI-MSI Based Hair Analysis
verfasst von: Bryn Flinders
Tom Bassindale
Ron M. A. Heeren
Verlag: Springer International Publishing
Buch: Emerging Technologies for the Analysis of Forensic Traces
Print ISBN: 978-3-030-20541-6

Electronic ISBN: 978-3-030-20542-3

Copyright-Jahr: 2019
DOI: https://doi.org/10.1007/978-3-030-20542-3_9

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