1989 | OriginalPaper | Buchkapitel
Remote Functionalization of Carbon-Hydrogen and Carbon-Carbon Bonds by Bare Transition Metal Ions in the Gas Phase
verfasst von : Gregor Czekay, Thomas Drewello, Karsten Eller, Carlito B. Lebrilla, Tilmann Prüsse, Christian Schulze, Norbert Steinrück, Detlev Sülzle, Thomas Weiske, Helmut Schwarz
Erschienen in: Organometallics in Organic Synthesis 2
Verlag: Springer Berlin Heidelberg
Enthalten in: Professional Book Archive
Aktivieren Sie unsere intelligente Suche, um passende Fachinhalte oder Patente zu finden.
Wählen Sie Textabschnitte aus um mit Künstlicher Intelligenz passenden Patente zu finden. powered by
Markieren Sie Textabschnitte, um KI-gestützt weitere passende Inhalte zu finden. powered by
The selective functionaIization of C-H bonds remains one of the major focuses of catalytic and organic chemistry. High selectivity is often achieved by the presence of activating groups which induce the reactivity of the neighbouring C-H bonds by, for example, polarizing the bond, thus making the hydrogen more acidic, or by generally weakening the C-H bond. The selective functionalization of hydrocarbon segments of a molecule remote from any functional group represents a great challenge. While such reactions are common to enzymes which coordinate a functional group and geometrically select a specific section of the molecule (see, for example, the enzymatic conversion of stearic to oleic acid. Scheme 1), only a few cases in solution chemistry are reported [1] where a similar principle seems to be operative.