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Medical & Biological Engineering & Computing
Erschienen in: Medical & Biological Engineering & Computing 8/2019

11.06.2019 | Original Article

Repolarization variability independent of heart rate during sympathetic activation elicited by head-up tilt

verfasst von: Fatima El-Hamad, Michal Javorka, Barbora Czippelova, Jana Krohova, Zuzana Turianikova, Alberto Porta, Mathias Baumert

Erschienen in: Medical & Biological Engineering & Computing | Ausgabe 8/2019

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Abstract

The fraction of repolarization variability independent of RR interval variability is of clinical interest. It has been linked to direct autonomic nervous system (ANS) regulation of the ventricles in healthy subjects and seems to reflect the instability of the ventricular repolarization process in heart disease. In this study, we sought to identify repolarization measures that best reflect the sympathetic influences on the ventricles independent of the RR interval. ECG was recorded in 46 young subjects during supine and then following 45 degrees head-up tilt. RR intervals and five repolarization features (QTend, QTpeak, RTend, RTpeak, and TpTe) were extracted from the ECG recordings. Repolarization variability was separated into RR-dependent and RR-independent variability using parametric spectral analysis. Results show that LF power of TpTe is independent of RR in both supine and tilt, while the LF power of QTend and RTend independent of RR and respiration increases following tilt. We conclude that TpTe is independent of RR and is highly affected by respiration. QTend and RTend LF power might reflect the sympathetic influences on the ventricles elicited by tilt.
Vorheriger Artikel Experimental and numerical investigation on soft tissue dynamic response due to turbulence-induced arterial vibration
Nächster Artikel Anatomical structure segmentation from early fetal ultrasound sequences using global pollination CAT swarm optimizer–based Chan–Vese model

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Metadaten
Titel
Repolarization variability independent of heart rate during sympathetic activation elicited by head-up tilt
verfasst von
Fatima El-Hamad
Michal Javorka
Barbora Czippelova
Jana Krohova
Zuzana Turianikova
Alberto Porta
Mathias Baumert
Publikationsdatum
11.06.2019
Verlag
Springer Berlin Heidelberg
Erschienen in
Medical & Biological Engineering & Computing / Ausgabe 8/2019
Print ISSN: 0140-0118
Elektronische ISSN: 1741-0444
DOI
https://doi.org/10.1007/s11517-019-01998-9

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