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Erschienen in:
2010 | OriginalPaper | Buchkapitel
Simplified Action Potential Models
verfasst von : Boris Ja. Kogan
Erschienen in: Introduction to Computational Cardiology
Verlag: Springer US
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The basic motivations for simplifying the AP mathematical models are: To make computer simulation of excitation wave propagation in 3D-tissue model with complex configuration feasible. To find a qualitative relationship between normal AP generation and propagation.
There are at least three known approaches used to simplify AP mathematical models: Based on singular perturbation theory Based on clamp-experiment data Based on the Van der Pole relaxation generator
In some cases, the sensitivity analysis [1] allows the introduction of some simplifications to modern sophisticated mathematical models.