Simulation help achieve the better in the industry in many ways. It reduces the waste in time and resources and increase efficiency in manufacturing. It also helps increase productivity and the revenue. Simulation has also significant role in the design of products. Furthermore, as the complexity in technology increase, skilled workers required by the industry can be trained by using simulation. Additionally, work safety issues are more important than it was in the past with the emergence of autonomous machines in manufacturing. The data will help create smartness and intelligence in manufacturing and simulation help data analytics in comprehension and knowledge extraction. This chapter is the concluding chapter of this book and summarizes the role of simulation in Industry 4.0. There are explicit and implicit imposed roles of simulation which are summarized in terms of technologies composed of Cyber-Physical Systems (CPS) and smart factory. In conclusion, as this book makes it clear with evidences, simulation is at the heart of Industry 4.0 and the main driver of the new industrial revolution.
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