Skip to main content

2017 | OriginalPaper | Buchkapitel

Smoluchowski Equation with Variable Coefficients in Perforated Domains: Homogenization and Applications to Mathematical Models in Medicine

verfasst von : Bruno Franchi, Silvia Lorenzani

Erschienen in: Harmonic Analysis, Partial Differential Equations and Applications

Verlag: Springer International Publishing

Aktivieren Sie unsere intelligente Suche, um passende Fachinhalte oder Patente zu finden.

search-config
loading …

Abstract

In this paper, we study the homogenization of a Smoluchowski system of periodic discrete diffusion-coagulation equations, when the diffusion coefficients depend on all variables, in particular on the microscopic variable. This system modelizes the aggregation and diffusion of the β-amyloid peptide Aβ 42 in the cerebral tissue, a process associated with the development of Alzheimer’s disease. Our homogenization result, based on Allaire-Nguetseng two-scale convergence, is meant to pass from a microscopic model to a macroscopic one.

Sie haben noch keine Lizenz? Dann Informieren Sie sich jetzt über unsere Produkte:

Springer Professional "Wirtschaft+Technik"

Online-Abonnement

Mit Springer Professional "Wirtschaft+Technik" erhalten Sie Zugriff auf:

  • über 102.000 Bücher
  • über 537 Zeitschriften

aus folgenden Fachgebieten:

  • Automobil + Motoren
  • Bauwesen + Immobilien
  • Business IT + Informatik
  • Elektrotechnik + Elektronik
  • Energie + Nachhaltigkeit
  • Finance + Banking
  • Management + Führung
  • Marketing + Vertrieb
  • Maschinenbau + Werkstoffe
  • Versicherung + Risiko

Jetzt Wissensvorsprung sichern!

Springer Professional "Technik"

Online-Abonnement

Mit Springer Professional "Technik" erhalten Sie Zugriff auf:

  • über 67.000 Bücher
  • über 390 Zeitschriften

aus folgenden Fachgebieten:

  • Automobil + Motoren
  • Bauwesen + Immobilien
  • Business IT + Informatik
  • Elektrotechnik + Elektronik
  • Energie + Nachhaltigkeit
  • Maschinenbau + Werkstoffe




 

Jetzt Wissensvorsprung sichern!

Springer Professional "Wirtschaft"

Online-Abonnement

Mit Springer Professional "Wirtschaft" erhalten Sie Zugriff auf:

  • über 67.000 Bücher
  • über 340 Zeitschriften

aus folgenden Fachgebieten:

  • Bauwesen + Immobilien
  • Business IT + Informatik
  • Finance + Banking
  • Management + Führung
  • Marketing + Vertrieb
  • Versicherung + Risiko




Jetzt Wissensvorsprung sichern!

Literatur
1.
Zurück zum Zitat Y. Achdou, B. Franchi, N. Marcello, M.C. Tesi, A qualitative model for aggregation and diffusion of β-Amyloid in Alzheimer’s disease. J. Math. Biol. 67 (6–7), 1369–1392 (2013)MathSciNetCrossRefMATH Y. Achdou, B. Franchi, N. Marcello, M.C. Tesi, A qualitative model for aggregation and diffusion of β-Amyloid in Alzheimer’s disease. J. Math. Biol. 67 (6–7), 1369–1392 (2013)MathSciNetCrossRefMATH
3.
Zurück zum Zitat G. Allaire, A. Damlamian, U. Hornung, Two-scale convergence on periodic surfaces and applications, in Proceedings of the International Conference on Mathematical Modelling of Flow Through Porous Media, ed. by A. Bourgeat et al. (World Scientific Publication, Singapore, 1996), pp. 15–25 G. Allaire, A. Damlamian, U. Hornung, Two-scale convergence on periodic surfaces and applications, in Proceedings of the International Conference on Mathematical Modelling of Flow Through Porous Media, ed. by A. Bourgeat et al. (World Scientific Publication, Singapore, 1996), pp. 15–25
4.
5.
Zurück zum Zitat M. Bertsch, B. Franchi, N. Marcello, M.C. Tesi, A. Tosin, Alzheimer’s disease: a mathematical model for onset and progression. Math. Med. Biol. (2016). doi:10.1093/imammb/dqw003 M. Bertsch, B. Franchi, N. Marcello, M.C. Tesi, A. Tosin, Alzheimer’s disease: a mathematical model for onset and progression. Math. Med. Biol. (2016). doi:10.1093/imammb/dqw003
6.
Zurück zum Zitat D. Cioranescu, P. Donato, An Introduction to Homogenization (Oxford University Press, Oxford, 1999)MATH D. Cioranescu, P. Donato, An Introduction to Homogenization (Oxford University Press, Oxford, 1999)MATH
7.
Zurück zum Zitat A. Damlamian, P. Donato, Which sequences of holes are admissible for periodic homogenization with Neumann boundary condition? ESAIM: COCV 8, 555–585 (2002)MathSciNetCrossRefMATH A. Damlamian, P. Donato, Which sequences of holes are admissible for periodic homogenization with Neumann boundary condition? ESAIM: COCV 8, 555–585 (2002)MathSciNetCrossRefMATH
8.
Zurück zum Zitat R.L. Drake, A general mathematical survey of the coagulation equation, in Topics in Current Aerosol Research (Part 2). International Reviews in Aerosol Physics and Chemistry (Pergamon Press, Oxford, 1972) R.L. Drake, A general mathematical survey of the coagulation equation, in Topics in Current Aerosol Research (Part 2). International Reviews in Aerosol Physics and Chemistry (Pergamon Press, Oxford, 1972)
9.
Zurück zum Zitat B. Franchi, S. Lorenzani, From a microscopic to a macroscopic model for Alzheimer disease: two-scale homogenization of the Smoluchowski equation in perforated domains. J. Nonlin. Sci. 26, 717–753 (2016)MathSciNetCrossRefMATH B. Franchi, S. Lorenzani, From a microscopic to a macroscopic model for Alzheimer disease: two-scale homogenization of the Smoluchowski equation in perforated domains. J. Nonlin. Sci. 26, 717–753 (2016)MathSciNetCrossRefMATH
10.
Zurück zum Zitat S. Giannuzzi, Equazione di Smoluchowski a coefficienti variabili e applicazioni. Master Thesis, School of Mathematics, University of Bologna (2015) S. Giannuzzi, Equazione di Smoluchowski a coefficienti variabili e applicazioni. Master Thesis, School of Mathematics, University of Bologna (2015)
11.
Zurück zum Zitat O.A. Ladyzenskaja, V.A. Solonnikov, N.N. Ural’ceva, Linear and Quasi-Linear Equations of Parabolic Type (American Mathematical Society, Providence, RI, 1968) O.A. Ladyzenskaja, V.A. Solonnikov, N.N. Ural’ceva, Linear and Quasi-Linear Equations of Parabolic Type (American Mathematical Society, Providence, RI, 1968)
12.
Zurück zum Zitat P. Laurençot, S. Mischler, Global existence for the discrete diffusive coagulation-fragmentation equations in L 1. Rev. Mat. Iberoamericana 18, 731–745 (2002)MathSciNetCrossRefMATH P. Laurençot, S. Mischler, Global existence for the discrete diffusive coagulation-fragmentation equations in L 1. Rev. Mat. Iberoamericana 18, 731–745 (2002)MathSciNetCrossRefMATH
13.
Zurück zum Zitat G.M. Lieberman, Second Order Parabolic Differential Equations (World Scientific Publisher, Singapore, 1996)CrossRefMATH G.M. Lieberman, Second Order Parabolic Differential Equations (World Scientific Publisher, Singapore, 1996)CrossRefMATH
14.
Zurück zum Zitat R.M. Murphy, M.M. Pallitto, Probing the kinetics of β-amyloid self-association. J. Struct. Biol. 130, 109–122 (2000)CrossRef R.M. Murphy, M.M. Pallitto, Probing the kinetics of β-amyloid self-association. J. Struct. Biol. 130, 109–122 (2000)CrossRef
15.
Zurück zum Zitat G. Nguetseng, A general convergence result for a functional related to the theory of homogenization. SIAM J. Math. Anal. 20, 608–623 (1989)MathSciNetCrossRefMATH G. Nguetseng, A general convergence result for a functional related to the theory of homogenization. SIAM J. Math. Anal. 20, 608–623 (1989)MathSciNetCrossRefMATH
17.
Zurück zum Zitat M. Smoluchowski, Versuch einer mathematischen theorie der koagulationskinetik kolloider lsungen. IZ Phys. Chem. 92, 129–168 (1917) M. Smoluchowski, Versuch einer mathematischen theorie der koagulationskinetik kolloider lsungen. IZ Phys. Chem. 92, 129–168 (1917)
18.
Zurück zum Zitat D. Wrzosek, Existence of solutions for the discrete coagulation-fragmentation model with diffusion. Topol. Methods Nonlin. Anal. 9 (2), 279–296 (1997)MathSciNetMATH D. Wrzosek, Existence of solutions for the discrete coagulation-fragmentation model with diffusion. Topol. Methods Nonlin. Anal. 9 (2), 279–296 (1997)MathSciNetMATH
Metadaten
Titel
Smoluchowski Equation with Variable Coefficients in Perforated Domains: Homogenization and Applications to Mathematical Models in Medicine
verfasst von
Bruno Franchi
Silvia Lorenzani
Copyright-Jahr
2017
DOI
https://doi.org/10.1007/978-3-319-52742-0_4