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Erschienen in:
Introduction and Background Information Kapitel lesen Erstes Kapitel lesen

2011 | OriginalPaper | Buchkapitel

3. Special Techniques

verfasst von : Prof. Dr. Kurt Faber

Erschienen in: Biotransformations in Organic Chemistry

Verlag: Springer Berlin Heidelberg

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Abstract

Most biocatalysts can be used in a straightforward manner by regarding them as chiral catalysts and by applying standard methodology, i.e., in buffered aqueous solution. In order to broaden the applicability of enzymes, some special techniques have been developed. In particular, using biocatalysts in nonaqueous media rather than in water can lead to the gain of some significant advantages as long as some specific guidelines are followed [1]. Furthermore, ‘fixation’ of the enzyme by immobilization may be necessary, and the use of membrane technology may be advantageous as well. For both of the latter topics only the most simple techniques which can be adopted in an average organic chemistry laboratory are discussed (Sect. 3.2).

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Vorheriges Kapitel Biocatalytic Applications
Nächstes Kapitel State of the Art and Outlook
Fußnoten
1
Tcrit 31°C and pcrit 73 bar.
 
2
In principle, ethyl fluoroacetate would also fall into this category. However, its use is not recommended since fluoroacetic acid is a severe toxin by acting as inhibitor of the Krebs-cycle.
 
3
For instance, glutamic acid dioleyl ester ribitol amide, didodecyl N-D-glucono-L-glutamate or Brij35.
 
4
For a rare case of selectivity-enhancement see [487].
 
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Metadaten
Titel
Special Techniques
verfasst von
Prof. Dr. Kurt Faber
Copyright-Jahr
2011
Verlag
Springer Berlin Heidelberg
Buch
Biotransformations in Organic Chemistry

Print ISBN: 978-3-642-17392-9

Electronic ISBN: 978-3-642-17393-6

Copyright-Jahr: 2011

DOI
https://doi.org/10.1007/978-3-642-17393-6_3

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