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2020 | OriginalPaper | Buchkapitel

40. Spezielle labortechnische Reaktoren: 3D-gedruckte Reaktoren

verfasst von : Eike G. Hübner, Felix Lederle

Erschienen in: Handbuch Chemische Reaktoren

Verlag: Springer Berlin Heidelberg

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Zusammenfassung

Kaum eine Technologie hat sich innerhalb der letzten Jahre so öffentlichkeitswirksam verbreitet wie die additive Fertigung. 3D-Drucker sind mittlerweile sowohl im Heimbereich als auch in der industriellen Fertigung anzutreffen. Anhand von zahlreichen Beispielen wird die fortschreitende Entwicklung von 3D-Drucktechniken für chemische Laboratorien dargestellt. Ausgehend von grundlegender Methodenevaluation finden heutzutage komplexe und präparativ nutzbare 3D-gedruckte Reaktoren breite Anwendung sowohl in der Mikro- und Millifluidik als auch in Form kreativ genutzter Batchreaktoren.

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Vorheriges Kapitel Spezielle labortechnische Reaktoren: TAP-Reaktor

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Ameloot, R.: Digital fabrication in catalytic technology. In: Sels, B., Van de Voorde, M. (Hrsg.) Nanotechnology in Catalysis: Applications in the Chemical Industry, Energy Development, and Environment Protection, S. 359–381. Wiley-VCH, Weinheim (2017)

Avril, A., Hornung, C.H., Urban, A., Fraser, D., Horne, M., Veder, J.-P., Tsanaktsidis, J., Rodopoulos, T., Henry, C., Gunasegaram, D.R.: Continuous flow hydrogenations using novel catalytic static mixers inside a tubular reactor. React. Chem. Eng. 2, 180–188 (2017)

Bertsch, A., Heimgartner, S., Cousseau, P., Renaud, P.: Static micromixers based on large-scale industrial mixer geometry. Lab Chip 1, 56–60 (2001)

Bettermann, S., Schroeter, B., Moritz, H.-U., Pauer, W., Fassbender, M., Luinstra, G.A.: Continuous emulsion copolymerization processes at mild conditions in a 3D-printed tubular bended reactor. Chem. Eng. J. 338, 311–322 (2018)

Capel, A.J., Edmondson, S., Christie, S.D.R., Goodridge, R.D., Bibb, R.J., Thurstans, M.: Design and additive manufacture for flow chemistry. Lab Chip 13, 4583–4590 (2013)

Capel, A.J., Wright, A., Harding, M.J., Weaver, G.W., Li, Y., Harris, R.A., Edmondson, S., Goodridge, R.D., Christie, S.D.R.: 3D printed fluidics with embedded analytic functionality for automated reaction optimisation. Beilstein J. Org. Chem. 13, 111–119 (2017)PubMedPubMedCentral

Díaz-Marta, A.S., Tubío, C.R., Carbajales, C., Fernández, C., Escalante, L., Sotelo, E., Guitián, F., Barrio, V.L., Gil, A., Coelho, A.: Three-dimensional printing in catalysis: Combining 3D heterogeneous copper and palladium catalysts for multicatalytic multicomponent reactions. ACS Catal. 8, 392–404 (2018)

Dragone, V., Sans, V., Rosnes, M.H., Kitson, P.J., Cronin, L.: 3D-printed devices for continuous-flow organic chemistry. Beilstein J. Org. Chem. 9, 951–959 (2013)PubMedPubMedCentral

Elias, Y., von Rohr, P.R., Bonrath, W., Medlock, J., Buss, A.: A porous structured reactor for hydrogenation reactions. Chem. Eng. Process. Process Intensif. 95, 175–185 (2015)

Erkal, J.L., Selimovic, A., Gross, B.C., Lockwood, S.Y., Walton, E.L., McNamara, S., Martin, R.S., Spence, D.M.: 3D printed microfluidic devices with integrated versatile and reusable electrodes. Lab Chip 14, 2023–2032 (2014)

Gelhausen, M.G., Lenz, D., Krull, F., Korkmaz, V., Agar, D.W.: 3D printing for chemical process laboratories II: Measuring liquid-solid mass transfer coefficients. Chem. Eng. Technol. 41, 798–805 (2018)

Gordeev, E.G., Degtyareva, E.S., Ananikov, V.P.: Analysis of 3D printing possibilities for the development of practical applications in synthetic organic chemistry. Russ. Chem. Bull. Int. Ed. 65, 1637–1643 (2016)

Gutmann, B., Köckinger, M., Glotz, G., Ciaglia, T., Slama, E., Zadravec, M., Pfanner, S., Maier, M.C., Gruber-Wölfler, H., Kappe, C.O.: Design and 3D printing of a stainless steel reactor for continuous difluoromethylations using fluoroform. React. Chem. Eng. 2, 919–927 (2017)

Hornung, C.H., Nguyen, X., Carafa, A., Gardiner, J., Urban, A., Fraser, D., Horne, M.D., Gunasegaram, D.R., Tsanaktsidis, J.: Use of catalytic static mixers for continuous flow gas-liquid and transfer hydrogenations in organic synthesis. Org. Process. Res. Dev. 21, 1311–1319 (2017)

Kanazawaka, S., Eto, K., Imagawa, W., Akamine, S., Ichiki, R.: 3D-printed atmospheric-pressure plasma reactors. Int. J. Plasma Environ. Sci. Technol. 9, 103–106 (2015)

Kazenwadel, F., Biegert, E., Wohlgemuth, J., Wagner, H., Franzreb, M.: A 3D-printed modular reactor setup including temperature and pH control for the compartmentalized implementation of enzyme cascades. Eng. Life Sci. 16, 560–567 (2016)

Kise, D.P., Reddish, M.J., Dyer, R.B.: Sandwich-format 3D printed microfluidic mixers: A flexible platform for multi-probe analysis. J. Micromech. Microeng. 25, 124002 (2015)PubMedPubMedCentral

Kitson, P.J., Rosnes, M.H., Sans, V., Dragone, V., Cronin, L.: Configurable 3D-printed millifluidic and microfluidic ‚lab on chip‘ reactionware devices. Lab Chip 12, 3267–3271 (2012)

Kitson, P.J., Symes, M.D., Dragone, V., Cronin, L.: Combining 3D printing and liquid handling to produce user-friendly reactionware for chemical synthesis and purification. Chem. Sci. 4, 3099–3103 (2013)

Kitson, P.J., Marshall, R.J., Long, D., Forgan, R.S., Cronin, L.: 3D printed high-throughput hydrothermal reactionware for discovery, optimization, and scale-up. Angew. Chem. Int. Ed. 53, 12723–12728 (2014)

Kitson, P.J., Glatzel, S., Cronin, L.: The digital code driven autonomous synthesis of ibuprofen automated in a 3D-printer based robot. Beilstein J. Org. Chem. 12, 2776–2783 (2016)PubMedPubMedCentral

Kitson, P.J., Marie, G., Francoia, J.-P., Zalesskiy, S.S., Sigerson, R.C., Mathieson, J.S., Cronin, L.: Digitization of multistep organic synthesis in reactionware for on-demand pharmaceuticals. Science 359, 314–319 (2018)PubMed

Knitter, R., Liauw, M.A.: Ceramic microreactors for heterogeneously catalysed gas-phase reactions. Lab Chip 4, 378–383 (2004)

Konarova, M., Aslam, W., Ge, L., Ma, Q., Tang, F., Rudolph, V., Beltramini, J.N.: Enabling process intensification by 3D printing of catalytic structures. Chem. Cat. Chem. 9, 4132–4138 (2017)

Lederle, F., Kaldun, C., Namyslo, J.C., Hübner, E.G.: 3D-printing inside the glovebox: A versatile tool for inert-gas chemistry combined with spectroscopy. Helv. Chim. Acta. 99, 255–266 (2016a)PubMedPubMedCentral

Lederle, F., Meyer, F., Brunotte, G.-P., Kaldun, C., Hübner, E.G.: Improved mechanical properties of 3D-printed parts by fused deposition modeling under the exclusion of oxygen. Prog. Addit. Manuf. 1, 3–7 (2016b)

Lederle, F., Meyer, F., Kaldun, C., Namyslo, J.C., Hübner, E.G.: Sonogashira coupling in 3D-printed NMR cuvettes: Synthesis and properties of arylnaphthylalkynes. New J. Chem. 41, 1925–1932 (2017)

Lücking, T.H., Sambale, F., Beutel, S., Scheper, T.: 3D-printed individual labware in biosciences by rapid prototyping: A proof of principle. Eng. Life Sci. 15, 51–56 (2015)

Manzano, J.S., Weinstein, Z.B., Sadow, A.D., Slowing, I.I.: Direct 3D printing of catalytically active structures. ACS Catal. 7, 7567–7577 (2017)

Marks, P.: 3D printing takes off with the world’s first printed plane. New Sci. 211, 17–18 (2011)

Mathieson, J.S., Rosnes, M.H., Sans, V., Kitson, P.J., Cronin, L.: Continuous parallel ESI-MS analysis of reactions carried out in a bespoke 3D printed device. Beilstein J. Nanotechnol. 4, 285–291 (2013)PubMedPubMedCentral

McDonald, J.C., Chabinyc, M.L., Metallo, S.J., Anderson, J.R., Stroock, A.D., Whitesides, G.M.: Prototyping of microfluidic devices in poly(dimethylsiloxane) using solid-object printing. Anal. Chem. 74, 1537–1545 (2002)PubMed

Michel, F.M., Rimstidt, J.D., Kletetschka, K.: 3D printed mixed flow reactor for geochemical rate measurements. Appl. Geochem. 89, 86–91 (2018)

Mousset, E., Weiqi, V.H., Kai, B.F.Y., Koh, J.S., Tng, J.W., Wang, Z., Lefebvre, O.: A new 3D-printed photoelectrocatalytic reactor combining the benefits of a transparent electrode and the Fenton reaction for advanced wastewater treatment. J. Mater. Chem. A 5, 24951–24964 (2017)

Okafor, O., Weilhard, A., Fernandes, J.A., Karjalainen, E., Goodridge, R., Sans, V.: Advanced reactor engineering with 3D printing for the continuous-flow synthesis of silver nanoparticles. React. Chem. Eng. 2, 129–136 (2017)

Parra-Cabrera, C., Achille, C., Kuhn, S., Ameloot, R.: 3D printing in chemical engineering and catalytic technology: Structured catalysts, mixers and reactors. Chem. Soc. Rev. 47, 209–230 (2018)PubMed

Peris, E., Okafor, O., Kulcinskaja, E., Goodridge, R., Luis, S.V., Garcia-Verdugo, E., O’Reilly, E., Sans, V.: Tuneable 3D printed bioreactos for transaminations under continuous-flow. Green Chem. 19, 5345–5349 (2017)

Rao, Z.X., Patel, B., Monaco, A., Cao, Z.J., Barniol-Xicota, M., Pichon, E., Ladlow, M., Hilton, S.T.: 3D-printed polypropylene continuous-flow column reactors: Exploration of reactor utility in S_NAr reactions and the synthesis of bicyclic and tetracyclic heterocycles. Eur. J. Org. Chem. 2017, 6499–6504 (2017)

Rogers, C.I., Qaderi, K., Woolley, A.T., Nordin, G.P.: 3D printed microfluidic devices with integrated valves. Biomicrofluidics 9, 016501 (2015)PubMedPubMedCentral

Rossi, S., Porta, R., Brenna, D., Puglisi, A., Benaglia, M.: Stereoselective catalytic synthesis of active pharmaceutical ingredients in homemade 3D-printed mesoreactors. Angew. Chem. Int. Ed. 56, 4290–4294 (2017)

Sandron, S., Heery, B., Gupta, V., Collins, D.A., Nesterenko, E.P., Nesterenko, P.N., Talebi, M., Beirne, S., Thompson, F., Wallace, G.G., Brabazon, D., Regan, F., Paull, B.: 3D printed metal columns for capillary liquid chromatography. Analyst 139, 6343–6347 (2014)PubMed

Scotti, G., Nilsson, S.M.E., Haapala, M., Pöhö, P., Af Gennäs, G.B., Yli-Kauhaluoma, J., Kotiaho, T.: A miniaturised 3D printed polypropylene reactor for online reaction analysis by mass spectrometry. React. Chem. Eng. 2, 299–303 (2017)

SpaceX (Space Exploration Technologies Corporation): SpaceX launches 3D-printed part to space, creates printed engine chamber. http://www.spacex.com/news/2014/07/31/spacex-launches-3d-printed-part-space-creates-printed-engine-chamber-crewed (2014). Zugegriffen am 07.02.2018

Stefanov, B.I., Lebrun, D., Mattsson, A., Granqvist, C.G., Österlund, L.: Demonstrating online monitoring of air pollutant photodegradation in a 3D printed gas-phase photocatalysis reactor. J. Chem. Educ. 92, 678–682 (2015)

Symes, M.D., Kitson, P.J., Yan, J., Richmond, C.J., Cooper, G.J.T., Bowman, R.W., Vilbrandt, T., Cronin, L.: Integrated 3D-printed reactionware for chemical synthesis and analysis. Nat. Chem. 4, 349–354 (2012)PubMed

Therriault, D., White, S.R., Lewis, J.A.: Chaotic mixing in three-dimensional microvascular networks fabricated by direct-write assembly. Nat. Mater. 2, 265–271 (2003)PubMed

Yuen, P.K.: Embedding objects during 3D printing to add new functionalities. Biomicrofluidics 10, 044104 (2016)PubMedPubMedCentral

Amin, R., Knowlton, S., Hart, A., Yenilmez, B., Ghaderinezhad, F., Katebifar, S., Messina, M., Khademhosseini, A., Tasoglu, S.: 3D-printed microfluidic devices. Biofabrication 8, 022001 (2016)PubMed

Au, A.K., Lee, W., Folch, A.: Mail-order microfluidics: Evaluation of stereolithography for the production of microfluidic devices. Lab Chip 14, 1294–1301 (2014)

Au, A.K., Huynh, W., Horowitz, L.F., Folch, A.: 3D-printed microfluidics. Angew. Chem. Int. Ed. 55, 3862–3881 (2016)

Bhattacharjee, N., Urrios, A., Kang, S., Folch, A.: The upcoming 3D-printing revolution in microfluidics. Lab Chip 16, 1720–1742 (2016)

Dizon, J.R.C., Espara Jr., A.H., Chen, Q., Advincula, R.C.: Mechanical characterization of 3D-printed polymers. Addit. Manuf. 20, 44–67 (2018)

Fitzpatrick, D.E., Battilocchio, C., Ley, S.V.: Enabling technologies for the future of chemical synthesis. ACS Cent. Sci. 2, 131–138 (2016)PubMedPubMedCentral

Gelhausen, M.G., Feuerbach, T., Schubert, A., Agar, D.W.: 3D printing for chemical process laboratories I: Materials and connection principles. Chem. Eng. Technol. 41, 618–627 (2018)

Gross, B.C., Erkal, J.L., Lockwood, S.Y., Chen, C., Spence, D.M.: Evaluation of 3D printing and its potential impact on biotechnology and the chemical sciences. Anal. Chem. 86, 3240–3253 (2014)PubMed

Gross, B., Lockwood, S.Y., Spence, D.M.: Recent advances in analytical chemistry by 3D printing. Anal. Chem. 89, 57–70 (2017)PubMed

He, Y., Wu, Y., Fu, J.-Z., Gao, Q., Qiu, J.-J. Developments of 3D printing microfluidics and applications in chemistry and biology: A review. Electroanalysis 28, 1658–1678 (2016)

Hurt, C., Brandt, M., Priya, S.S., Bhatelia, T., Patel, J., Selvakannan, P.R., Bhargava, S.: Combining additive manufacturing and catalysis: A review. Catal. Sci. Technol. 7, 3421–3439 (2017)

Ligon, S.C., Liska, R., Stampfl, J., Gurr, M., Mülhaupt, R.: Polymers for 3D printing and customized additive manufacturing. Chem. Rev. 117, 10212–10290 (2017)PubMedPubMedCentral

Macdonald, N.P., Cabot, J.M., Smejkal, P., Guijt, R.M., Paull, B., Breadmore, M.C.: Comparing microfluidic performance of three-dimensional (3D) printing platforms. Anal. Chem. 89, 3858–3866 (2017)PubMed

Rossi, S., Puglisi, A., Benaglia, M.: Additive manufacturing technologies: 3D printing in organic synthesis. ChemCatChem 10, 1512–1525 (2018)

Sochol, R.D., Sweet, E., Glick, C.C., Venkatesh, S., Avetisyan, A., Ekman, K.F., Raulinaitis, A., Tsai, A., Wienkers, A., Korner, K., Hanson, K., Long, A., Hightower, B.J., Slatton, G., Burnett, D.C., Massey, T.L., Iwai, K., Lee, L.P., Pister, K.S.J., Lin, L.: 3D printed microfluidic circuitry via multijet-based additive manufacturing. Lab Chip 16, 668–678 (2016)

Stark, A.K.: Manufactured chemistry: Rethinking unit operation design in the age of additive manufacturing. AIChE J. 64, 1162–1173 (2018)

Waheed, S., Cabot, J.M., Macdonald, N.P., Lewis, T., Guijt, R.M., Paull, B., Breadmore, M.C.: 3D printed microfluidic devices: Enablers and barriers. Lab Chip 16, 1993–2013 (2016)

Yazdi, A.A., Popma, A., Wong, W., Nguyen, T., Pan, Y., Xu, J.: 3D printing: An emerging tool for novel microfluidics and lab-on-a-chip applications. Microfluid. Nanofluid. 20, 50 (2016)

Zhou, X., Liu, C.-J.: Three-dimensional printing for catalytic applications: Current status and perspectives. Adv. Funct. Mater. 27, 1701134 (2017)

Zwicker, A.P., Bloom, J., Albertson, R., Gershman, S.: The suitability of 3D printed plastic parts for laboratory use. Am. J. Phys. 83, 281–285 (2014)

Titel: Spezielle labortechnische Reaktoren: 3D-gedruckte Reaktoren
verfasst von: Eike G. Hübner
Felix Lederle
Verlag: Springer Berlin Heidelberg
Buch: Handbuch Chemische Reaktoren
Print ISBN: 978-3-662-56433-2

Electronic ISBN: 978-3-662-56434-9

Copyright-Jahr: 2020
DOI: https://doi.org/10.1007/978-3-662-56434-9_48