Zearalenone is an estrogen produced by several species of Fusarium on corn and other cereal grains (Caldwell and Tuite, 1974; Gross and Robb, 1975; Bottalico, 1979). Its presence in animal feeds and subsequent consumption have been associated with hyperestrogenism and other reproductive disorders in swine (Miller et al., 1973), poultry (Meronuck et al., 1970; Allen et al., 1981a,b) and cattle (Mirocha et al., 1968). Zearalenol, which is produced in its two epimeric forms as a metabolic precursor of zearalenone by certain species of Fusarium exhibits estrogenic activity (Peters, 1972; Mirocha et al., 1978; Bottalico et al., 1985; Richardson et al., 1985). α-Zearalenol has three to four times as much estrogenic activity as zearalenone while β-zearalenol has about the same or slightly less estrogenicity as zearalenone (Peters, 1972; Mirocha et al., 1978; Hagler et al., 1979). Zearalenone and zearalenol also have some anabolic activity that is useful in animal nutrition (Hidy et al., 1977).
Weitere Kapitel dieses Buchs durch Wischen aufrufen
- Stimulation of Zearalenone Production in Rice Cultures of Fusarium Semitectum by Addition of Zearalenone and α-and β-Zearalenol
K. E. Richardson
W. M. Hagler Jr
P. B. Hamilton
- Springer US
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