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Solid-State Nanopore Sensors for Nucleic Acid Analysis Kapitel lesen Erstes Kapitel lesen

2011 | OriginalPaper | Buchkapitel

13. Stochastic Detection of Terrorist Agents and Biomolecules in a Biological Channel

verfasst von : Xiyun Guan, Ranulu Samanthi S. de Zoysa, Dilani A. Jayawardhana, Qitao Zhao

Erschienen in: Nanopores

Verlag: Springer US

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Abstract

Stochastic sensing can detect analytes at the single-molecule level, in which a biological ion channel embedded in a lipid bilayer or a nano-scale sized pore fabricated in a solid-state membrane is used as the sensing element. By monitoring the ionic current modulations induced by the passage of the target analyte through the single pore, both the concentration and the identity of the analyte can be revealed. In this chapter, we highlight recent advances in the stochastic detection of terrorist agents and biomolecules, and in real-world sample analysis using alpha-hemolysin protein ion channels.

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Vorheriges Kapitel Third Generation DNA Sequencing with a Nanopore
Nächstes Kapitel Nanopore Force Spectroscopy: Insights from Molecular Dynamics Simulations
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Metadaten
Titel
Stochastic Detection of Terrorist Agents and Biomolecules in a Biological Channel
verfasst von
Xiyun Guan
Ranulu Samanthi S. de Zoysa
Dilani A. Jayawardhana
Qitao Zhao
Copyright-Jahr
2011
Verlag
Springer US
Buch
Nanopores

Print ISBN: 978-1-4419-8251-3

Electronic ISBN: 978-1-4419-8252-0

Copyright-Jahr: 2011

DOI
https://doi.org/10.1007/978-1-4419-8252-0_13

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