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Erschienen in:
Free Energy-Based Methods to Understand Drug Resistance Mutations Kapitel lesen Erstes Kapitel lesen

2019 | OriginalPaper | Buchkapitel

Structure-Based Drug Design with a Special Emphasis on Herbal Extracts

verfasst von : D. Velmurugan, N. H. V. Kutumbarao, V. Viswanathan, Atanu Bhattacharjee

Erschienen in: Structural Bioinformatics: Applications in Preclinical Drug Discovery Process

Verlag: Springer International Publishing

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Abstract

Structure-based drug design (SBDD) is a computational analysis of identifying ligands which can potentially inhibit the target. SBDD is a cluster of methods and modules which reduces the cost and time spent on experimental procedures. SBDD plays a crucial role in preclinical drug development procedures. There is a vast development in techniques and methods related to theoretical physics and chemistry, computers processers, and pharmacokinetic analysis which helps in elucidating the biological role of ligands and their receptors. Here, the general theoretical backgrounds of various SBDD and simulation approaches employed are discussed. These methods are also discussed with respect to the identification of potential drug-like molecules from natural sources to control human ailments.

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Vorheriges Kapitel Integrated Chemoinformatics Approaches Toward Epigenetic Drug Discovery
Nächstes Kapitel Impact of Target-Based Drug Design in Anti-bacterial Drug Discovery for the Treatment of Tuberculosis
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Metadaten
Titel
Structure-Based Drug Design with a Special Emphasis on Herbal Extracts
verfasst von
D. Velmurugan
N. H. V. Kutumbarao
V. Viswanathan
Atanu Bhattacharjee
Copyright-Jahr
2019
Buch
Structural Bioinformatics: Applications in Preclinical Drug Discovery Process

Print ISBN: 978-3-030-05281-2

Electronic ISBN: 978-3-030-05282-9

Copyright-Jahr: 2019

DOI
https://doi.org/10.1007/978-3-030-05282-9_9