The objective of this study was to assess the long-term stability and mechanical strength of a novel unidirectional porous hydroxyapatite (UDPHAp). Thirty-five Japanese white rabbits were used in the study. A cylindrical piece of UDPHAp was implanted in the femoral marrow. The animals were sacrificed 6, 12, 52 and 104 weeks after implantation. Compression strength was measured in a direction parallel to that of the unidirectional pores. The mean compression strength of the control sample before implantation was 13.4 MPa. The mean compression strength was 29.5 MPa, 43.5 MPa, 49.2 Mpa, 39.4 MPa and 45.8 MPa at 6, 12, 26, 52 and 104 weeks after implantation, respectively. Statistically significant differences were observed between the control samples and the implanted samples at all time points and between the implanted samples tested at 6 and 26 weeks after implantation. UDPHAp offers an advantage with regard to mechanical strength in that the compression strength in the direction parallel to that of the unidirectional pores increases at an early stage after implantation in the living bone tissue and is maintained for at least 2 years.
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- Study of the Mechanical Properties of a Novel Unidirectional Porous Hydroxyapatite Implanted in the Femoral Marrow of a Rabbit
- Springer Berlin Heidelberg