There are similarities in the distribution of Substance P (SP) and enkephalins in the central and peripheral nervous systems. SP and methionine enkephalin (MEK) exhibited opposing effects on nociception, uptake of Ca++ ions by the nervous tissue, release of ACh and modulation of cholinergic function [1–3]. Peripheral branches of certain primary-afferent neurons liberated SP as a neurotransmitter in autonomic post-ganglionic cells and caused long-lasting increase in the excitability of ganghon cells to the primary transmitter, ACh . The male genital system, its glands (seminal vesicles prostate, epididymis) and plexus (vesical, prostatic, cavernous) have rich autonomic and sensory or afferent innervation. However, little information is available about the role of SP in the male genital system.
Weitere Kapitel dieses Buchs durch Wischen aufrufen
- Substance P in Human Spermatozoa and Modulation of Sperm Motility by Substance P and Its Antagonists
B. V. Rama Sastry
V. E. Janson
- Springer New York
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