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2018 | OriginalPaper | Buchkapitel

1. Supramolecular Self-assembled Nanomaterials for Fluorescence Bioimaging

verfasst von : Lei Wang, Guo-Bin Qi

Erschienen in: In Vivo Self-Assembly Nanotechnology for Biomedical Applications

Verlag: Springer Singapore

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Abstract

In recent years, the construction of self-assembled nanomaterials with diversified structures and functionalities via fine tune of supramolecular building blocks increases rapidly. The self-assembled nanomaterials are potential high-efficient probes/contrast agents for high-performance fluorescence imaging techniques, which show distinguished advantages in terms of the availability of biocompatible imaging agents, maneuverable instruments, and high temporal resolution with good sensitivity. Generally, the self-assembled nanomaterials show high stability in vivo, prolonged half-life, and desirable targeting properties. Furthermore, self-assembled nanomaterials can be modulated by intelligent stimuli due to the dynamic nature of supramolecular materials. In this chapter, we will summarize recent advances in smart self-assembled nanomaterials as fluorescence probes/contrast agents for biomedical imaging, including long-term imaging, enzyme activity detection, and aggregation-induced retention (AIR) effect for diagnosis and therapy. The self-assembled nanomaterials will be classified into two groups, i.e., the ex situ and in situ self-assembled nanomaterials based on the assembly mode and the strategy for fluorescence regulation. Finally, we conclude with an outlook toward future developments of self-assembled nanomaterials for fluorescence bioimaging.

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Literatur
1.
Zurück zum Zitat Lehn J-M (1988) Supramolecular chemistry-scope and perspectives molecules, supermolecules, and molecular devices (Nobel Lecture). Angew Chem Int Ed 27(1):89–112CrossRef Lehn J-M (1988) Supramolecular chemistry-scope and perspectives molecules, supermolecules, and molecular devices (Nobel Lecture). Angew Chem Int Ed 27(1):89–112CrossRef
2.
Zurück zum Zitat Li F, Lu J, Kong X, Hyeon T, Ling D (2017) Dynamic nanoparticle assemblies for biomedical applications. Adv Mater:1605897CrossRef Li F, Lu J, Kong X, Hyeon T, Ling D (2017) Dynamic nanoparticle assemblies for biomedical applications. Adv Mater:1605897CrossRef
3.
Zurück zum Zitat Wang L, L-l Li, Y-s Fan, Wang H (2013) Host–guest supramolecular nanosystems for cancer diagnostics and therapeutics. Adv Mater 25(28):3888–3898CrossRef Wang L, L-l Li, Y-s Fan, Wang H (2013) Host–guest supramolecular nanosystems for cancer diagnostics and therapeutics. Adv Mater 25(28):3888–3898CrossRef
4.
Zurück zum Zitat de Silva AP, Gunaratne HQN, Gunnlaugsson T, Huxley AJM, McCoy CP, Rademacher JT, Rice TE (1997) Signaling recognition events with fluorescent sensors and switches. Chem Rev 97(5):1515–1566CrossRef de Silva AP, Gunaratne HQN, Gunnlaugsson T, Huxley AJM, McCoy CP, Rademacher JT, Rice TE (1997) Signaling recognition events with fluorescent sensors and switches. Chem Rev 97(5):1515–1566CrossRef
5.
Zurück zum Zitat Michalet X, Pinaud FF, Bentolila LA, Tsay JM, Doose S, Li JJ, Sundaresan G, Wu AM, Gambhir SS, Weiss S (2005) Quantum dots for live cells, in vivo imaging, and diagnostics. Science 307(5709):538–544CrossRef Michalet X, Pinaud FF, Bentolila LA, Tsay JM, Doose S, Li JJ, Sundaresan G, Wu AM, Gambhir SS, Weiss S (2005) Quantum dots for live cells, in vivo imaging, and diagnostics. Science 307(5709):538–544CrossRef
6.
Zurück zum Zitat de Chermont QlM, Chaneac C, Seguin J, Pelle F, Maitrejean S, Jolivet J-P, Gourier D, Bessodes M, Scherman D (2007) Nanoprobes with near-infrared persistent luminescence for in vivo imaging. Proc Natl Acad Sci USA 104(22):9266–9271 de Chermont QlM, Chaneac C, Seguin J, Pelle F, Maitrejean S, Jolivet J-P, Gourier D, Bessodes M, Scherman D (2007) Nanoprobes with near-infrared persistent luminescence for in vivo imaging. Proc Natl Acad Sci USA 104(22):9266–9271
7.
Zurück zum Zitat He S, Song B, Li D, Zhu C, Qi W, Wen Y, Wang L, Song S, Fang H, Fan C (2010) A graphene nanoprobe for rapid, sensitive, and multicolor fluorescent DNA analysis. Adv Funct Mater 20(3):453–459CrossRef He S, Song B, Li D, Zhu C, Qi W, Wen Y, Wang L, Song S, Fang H, Fan C (2010) A graphene nanoprobe for rapid, sensitive, and multicolor fluorescent DNA analysis. Adv Funct Mater 20(3):453–459CrossRef
8.
Zurück zum Zitat Ding D, Li K, Liu B, Tang BZ (2013) Bioprobes based on AIE Fluorogens. Acc Chem Res 46(11):2441–2453CrossRef Ding D, Li K, Liu B, Tang BZ (2013) Bioprobes based on AIE Fluorogens. Acc Chem Res 46(11):2441–2453CrossRef
9.
Zurück zum Zitat Bao B, Fan Q, Wang L, Huang W (2014) Recent advances in fluorescent conjugated polymer nanoparticles. Sci China Chem 44(3):282–294 Bao B, Fan Q, Wang L, Huang W (2014) Recent advances in fluorescent conjugated polymer nanoparticles. Sci China Chem 44(3):282–294
10.
Zurück zum Zitat Chen M, Yin M (2014) Design and development of fluorescent nanostructures for bioimaging. Prog Polym Sci 39(2):365–395CrossRef Chen M, Yin M (2014) Design and development of fluorescent nanostructures for bioimaging. Prog Polym Sci 39(2):365–395CrossRef
11.
Zurück zum Zitat Razgulin A, Ma N, Rao J (2011) Strategies for in vivo imaging of enzyme activity: an overview and recent advances. Chem Soc Rev 40(7):4186–4216CrossRef Razgulin A, Ma N, Rao J (2011) Strategies for in vivo imaging of enzyme activity: an overview and recent advances. Chem Soc Rev 40(7):4186–4216CrossRef
12.
Zurück zum Zitat Tao Z, Hong G, Shinji C, Chen C, Diao S, Antaris AL, Zhang B, Zou Y, Dai H (2013) Biological imaging using nanoparticles of small organic molecules with fluorescence emission at wavelengths longer than 1000 nm. Angew Chem Int Ed 52(49):13002–13006CrossRef Tao Z, Hong G, Shinji C, Chen C, Diao S, Antaris AL, Zhang B, Zou Y, Dai H (2013) Biological imaging using nanoparticles of small organic molecules with fluorescence emission at wavelengths longer than 1000 nm. Angew Chem Int Ed 52(49):13002–13006CrossRef
13.
Zurück zum Zitat Wu C, Schneider T, Zeigler M, Yu J, Schiro PG, Burnham DR, McNeill JD, Chiu DT (2010) Bioconjugation of ultrabright semiconducting polymer dots for specific cellular targeting. J Am Chem Soc 132(43):15410–15417CrossRef Wu C, Schneider T, Zeigler M, Yu J, Schiro PG, Burnham DR, McNeill JD, Chiu DT (2010) Bioconjugation of ultrabright semiconducting polymer dots for specific cellular targeting. J Am Chem Soc 132(43):15410–15417CrossRef
14.
Zurück zum Zitat Peng HS, Stolwijk JA, Sun LN, Wegener J, Wolfbeis OS (2010) A nanogel for ratiometric fluorescent sensing of intracellular pH values. Angew Chem Int Ed 49(25):4246–4249CrossRef Peng HS, Stolwijk JA, Sun LN, Wegener J, Wolfbeis OS (2010) A nanogel for ratiometric fluorescent sensing of intracellular pH values. Angew Chem Int Ed 49(25):4246–4249CrossRef
15.
Zurück zum Zitat Wei H, Zhuo RX, Zhang XZ (2013) Design and development of polymeric micelles with cleavable links for intracellular drug delivery. Prog Polym Sci 38(3–4):503–535CrossRef Wei H, Zhuo RX, Zhang XZ (2013) Design and development of polymeric micelles with cleavable links for intracellular drug delivery. Prog Polym Sci 38(3–4):503–535CrossRef
16.
Zurück zum Zitat Yin MZ, Shen J, Pisula W, Liang MH, Zhi LJ, Müllen K (2009) Functionalization of self-assembled hexa-peri-hexabenzocoronene fibers with peptides for bioprobing. J Am Chem Soc 131(41):14618–14619CrossRef Yin MZ, Shen J, Pisula W, Liang MH, Zhi LJ, Müllen K (2009) Functionalization of self-assembled hexa-peri-hexabenzocoronene fibers with peptides for bioprobing. J Am Chem Soc 131(41):14618–14619CrossRef
17.
Zurück zum Zitat Luo J, Lei T, Wang L, Ma YG, Cao Y, Wang J, Pei J (2009) Highly fluorescent rigid supramolecular polymeric nanowires constructed through multiple hydrogen bonds. J Am Chem Soc 131(6):2076–2077CrossRef Luo J, Lei T, Wang L, Ma YG, Cao Y, Wang J, Pei J (2009) Highly fluorescent rigid supramolecular polymeric nanowires constructed through multiple hydrogen bonds. J Am Chem Soc 131(6):2076–2077CrossRef
18.
Zurück zum Zitat Yin MZ, Feng CL, Shen J, Yu YM, Xu ZJ, Yang WT, Knoll W, Müllen K (2011) Dual-responsive interaction to detect DNA on template-based fluorescent nanotubes. Small 7(12):1629–1634CrossRef Yin MZ, Feng CL, Shen J, Yu YM, Xu ZJ, Yang WT, Knoll W, Müllen K (2011) Dual-responsive interaction to detect DNA on template-based fluorescent nanotubes. Small 7(12):1629–1634CrossRef
19.
Zurück zum Zitat Zhang D, Zhao Y-X, Qiao Z-Y, Mayerhöffer U, Spenst P, Li X-J, Würthner F, Wang H (2014) Nano-confined squaraine dye assemblies: new photoacoustic and near-infrared fluorescence dual-modular imaging probes in vivo. Bioconj Chem 25(11):2021–2029CrossRef Zhang D, Zhao Y-X, Qiao Z-Y, Mayerhöffer U, Spenst P, Li X-J, Würthner F, Wang H (2014) Nano-confined squaraine dye assemblies: new photoacoustic and near-infrared fluorescence dual-modular imaging probes in vivo. Bioconj Chem 25(11):2021–2029CrossRef
20.
Zurück zum Zitat Bunschoten A, Buckle T, Kuil J, Luker GD, Luker KE, Nieweg OE, van Leeuwen FWB (2012) Targeted non-covalent self-assembled nanoparticles based on human serum albumin. Biomaterials 33(3):867–875CrossRef Bunschoten A, Buckle T, Kuil J, Luker GD, Luker KE, Nieweg OE, van Leeuwen FWB (2012) Targeted non-covalent self-assembled nanoparticles based on human serum albumin. Biomaterials 33(3):867–875CrossRef
21.
Zurück zum Zitat Chen Q, Liang C, Wang X, He J, Li Y, Liu Z (2014) An albumin-based theranostic nano-agent for dual-modal imaging guided photothermal therapy to inhibit lymphatic metastasis of cancer post surgery. Biomaterials 35(34):9355–9362CrossRef Chen Q, Liang C, Wang X, He J, Li Y, Liu Z (2014) An albumin-based theranostic nano-agent for dual-modal imaging guided photothermal therapy to inhibit lymphatic metastasis of cancer post surgery. Biomaterials 35(34):9355–9362CrossRef
22.
Zurück zum Zitat Chen Q, Wang C, Zhan Z, He W, Cheng Z, Li Y, Liu Z (2014) Near-infrared dye bound albumin with separated imaging and therapy wavelength channels for imaging-guided photothermal therapy. Biomaterials 35(28):8206–8214CrossRef Chen Q, Wang C, Zhan Z, He W, Cheng Z, Li Y, Liu Z (2014) Near-infrared dye bound albumin with separated imaging and therapy wavelength channels for imaging-guided photothermal therapy. Biomaterials 35(28):8206–8214CrossRef
23.
Zurück zum Zitat Sheng Z, Hu D, Zheng M, Zhao P, Liu H, Gao D, Gong P, Gao G, Zhang P, Ma Y, Cai L (2014) Smart human serum albumin-indocyanine green nanoparticles generated by programmed assembly for dual-modal imaging-guided cancer synergistic phototherapy. ACS Nano 8(12):12310–12322CrossRef Sheng Z, Hu D, Zheng M, Zhao P, Liu H, Gao D, Gong P, Gao G, Zhang P, Ma Y, Cai L (2014) Smart human serum albumin-indocyanine green nanoparticles generated by programmed assembly for dual-modal imaging-guided cancer synergistic phototherapy. ACS Nano 8(12):12310–12322CrossRef
24.
Zurück zum Zitat Gao F-P, Lin Y-X, Li L-L, Liu Y, Mayerhoeffer U, Spenst P, Su J-G, Li J-Y, Würthner F, Wang H (2014) Supramolecular adducts of squaraine and protein for noninvasive tumor imaging and photothermal therapy in vivo. Biomaterials 35(3):1004–1014CrossRef Gao F-P, Lin Y-X, Li L-L, Liu Y, Mayerhoeffer U, Spenst P, Su J-G, Li J-Y, Würthner F, Wang H (2014) Supramolecular adducts of squaraine and protein for noninvasive tumor imaging and photothermal therapy in vivo. Biomaterials 35(3):1004–1014CrossRef
25.
Zurück zum Zitat Wu C, Hansen SJ, Hou Q, Yu J, Zeigler M, Jin Y, Burnham DR, McNeill JD, Olson JM, Chiu DT (2011) Design of highly emissive polymer dot bioconjugates for in vivo tumor targeting. Angew Chem Int Ed 50(15):3430–3434CrossRef Wu C, Hansen SJ, Hou Q, Yu J, Zeigler M, Jin Y, Burnham DR, McNeill JD, Olson JM, Chiu DT (2011) Design of highly emissive polymer dot bioconjugates for in vivo tumor targeting. Angew Chem Int Ed 50(15):3430–3434CrossRef
26.
Zurück zum Zitat Ye F, Wu C, Jin Y, Chan Y-H, Zhang X, Chiu DT (2011) Ratiometric temperature sensing with semiconducting polymer dots. J Am Chem Soc 133(21):8146–8149CrossRef Ye F, Wu C, Jin Y, Chan Y-H, Zhang X, Chiu DT (2011) Ratiometric temperature sensing with semiconducting polymer dots. J Am Chem Soc 133(21):8146–8149CrossRef
27.
Zurück zum Zitat Chan Y-H, Ye F, Gallina ME, Zhang X, Jin Y, Wu IC, Chiu DT (2012) Hybrid semiconducting polymer dot-quantum dot with narrow-band emission, near-infrared fluorescence, and high brightness. J Am Chem Soc 134(17):7309–7312CrossRef Chan Y-H, Ye F, Gallina ME, Zhang X, Jin Y, Wu IC, Chiu DT (2012) Hybrid semiconducting polymer dot-quantum dot with narrow-band emission, near-infrared fluorescence, and high brightness. J Am Chem Soc 134(17):7309–7312CrossRef
28.
Zurück zum Zitat Yu J, Wu C, Zhang X, Ye F, Gallina ME, Rong Y, Wu IC, Sun W, Chan Y-H, Chiu DT (2012) Stable functionalization of small semiconducting polymer dots via covalent cross-linking and their application for specific cellular imaging. Adv Mater 24(26):3498–3504CrossRef Yu J, Wu C, Zhang X, Ye F, Gallina ME, Rong Y, Wu IC, Sun W, Chan Y-H, Chiu DT (2012) Stable functionalization of small semiconducting polymer dots via covalent cross-linking and their application for specific cellular imaging. Adv Mater 24(26):3498–3504CrossRef
29.
Zurück zum Zitat Peng H-S, Chiu DT (2015) Soft fluorescent nanomaterials for biological and biomedical imaging. Chem Soc Rev 44(14):4699–4722CrossRef Peng H-S, Chiu DT (2015) Soft fluorescent nanomaterials for biological and biomedical imaging. Chem Soc Rev 44(14):4699–4722CrossRef
30.
Zurück zum Zitat Xiong L, Shuhendler AJ, Rao J (2012) Self-luminescing BRET-FRET near-infrared dots for in vivo lymph-node mapping and tumour imaging. Nat Commun 3:1193CrossRef Xiong L, Shuhendler AJ, Rao J (2012) Self-luminescing BRET-FRET near-infrared dots for in vivo lymph-node mapping and tumour imaging. Nat Commun 3:1193CrossRef
31.
Zurück zum Zitat Shuhendler AJ, Pu K, Cui L, Uetrecht JP, Rao J (2014) Real-time imaging of oxidative and nitrosative stress in the liver of live animals for drug-toxicity testing. Nat Biotechnol 32(4):373–380CrossRef Shuhendler AJ, Pu K, Cui L, Uetrecht JP, Rao J (2014) Real-time imaging of oxidative and nitrosative stress in the liver of live animals for drug-toxicity testing. Nat Biotechnol 32(4):373–380CrossRef
32.
Zurück zum Zitat Palner M, Pu K, Shao S, Rao J (2015) Semiconducting polymer nanoparticles with persistent near-infrared luminescence for in vivo optical imaging. Angew Chem Int Ed 54(39):11477–11480CrossRef Palner M, Pu K, Shao S, Rao J (2015) Semiconducting polymer nanoparticles with persistent near-infrared luminescence for in vivo optical imaging. Angew Chem Int Ed 54(39):11477–11480CrossRef
33.
Zurück zum Zitat Feng L, Zhu C, Yuan H, Liu L, Lv F, Wang S (2013) Conjugated polymer nanoparticles: preparation, properties, functionalization and biological applications. Chem Soc Rev 42(16):6620–6633CrossRef Feng L, Zhu C, Yuan H, Liu L, Lv F, Wang S (2013) Conjugated polymer nanoparticles: preparation, properties, functionalization and biological applications. Chem Soc Rev 42(16):6620–6633CrossRef
34.
Zurück zum Zitat Jeong K, Park S, Lee YD, Lim CK, Kim J, Chung BH, Kwon IC, Park CR, Kim S (2013) Conjugated polymer/photochromophore binary nanococktails: bistable photoswitching of near-infrared fluorescence for in vivo imaging. Adv Mater 25(39):5574–5580CrossRef Jeong K, Park S, Lee YD, Lim CK, Kim J, Chung BH, Kwon IC, Park CR, Kim S (2013) Conjugated polymer/photochromophore binary nanococktails: bistable photoswitching of near-infrared fluorescence for in vivo imaging. Adv Mater 25(39):5574–5580CrossRef
35.
Zurück zum Zitat Jin Y, Ye F, Zeigler M, Wu C, Chiu DT (2011) Near-infrared fluorescent dye-doped semiconducting polymer dots. ACS Nano 5(2):1468–1475CrossRef Jin Y, Ye F, Zeigler M, Wu C, Chiu DT (2011) Near-infrared fluorescent dye-doped semiconducting polymer dots. ACS Nano 5(2):1468–1475CrossRef
36.
Zurück zum Zitat Danhier F, Ansorena E, Silva JM, Coco R, Le Breton A, Preat V (2012) PLGA-based nanoparticles: an overview of biomedical applications. J Control Release 161(2):505–522CrossRef Danhier F, Ansorena E, Silva JM, Coco R, Le Breton A, Preat V (2012) PLGA-based nanoparticles: an overview of biomedical applications. J Control Release 161(2):505–522CrossRef
37.
Zurück zum Zitat Li K, Pan J, Feng SS, Wu AW, Pu KY, Liu YT, Liu B (2009) Generic strategy of preparing fluorescent conjugated-polymer-loaded poly(DL-lactide-co-glycolide) nanoparticles for targeted cell imaging. Adv Funct Mater 19(22):3535–3542CrossRef Li K, Pan J, Feng SS, Wu AW, Pu KY, Liu YT, Liu B (2009) Generic strategy of preparing fluorescent conjugated-polymer-loaded poly(DL-lactide-co-glycolide) nanoparticles for targeted cell imaging. Adv Funct Mater 19(22):3535–3542CrossRef
38.
Zurück zum Zitat Li K, Liu YT, Pu KY, Feng SS, Zhan RY, Liu B (2011) Polyhedral oligomeric silsesquioxanes-containing conjugated polymer loaded PLGA nanoparticles with trastuzumab (herceptin) functionalization for HER2-positive cancer cell detection. Adv Funct Mater 21(2):287–294CrossRef Li K, Liu YT, Pu KY, Feng SS, Zhan RY, Liu B (2011) Polyhedral oligomeric silsesquioxanes-containing conjugated polymer loaded PLGA nanoparticles with trastuzumab (herceptin) functionalization for HER2-positive cancer cell detection. Adv Funct Mater 21(2):287–294CrossRef
39.
Zurück zum Zitat Hong Y, Lam JWY, Tang BZ (2011) Aggregation-induced emission. Chem Soc Rev 40(11):5361–5388CrossRef Hong Y, Lam JWY, Tang BZ (2011) Aggregation-induced emission. Chem Soc Rev 40(11):5361–5388CrossRef
40.
Zurück zum Zitat Qin A, Lam JWY, Tang BZ (2012) Luminogenic polymers with aggregation-induced emission characteristics. Prog Polym Sci 37(1):182–209CrossRef Qin A, Lam JWY, Tang BZ (2012) Luminogenic polymers with aggregation-induced emission characteristics. Prog Polym Sci 37(1):182–209CrossRef
41.
Zurück zum Zitat Hu R, Leung NLC, Tang BZ (2014) AIE macromolecules: syntheses, structures and functionalities. Chem Soc Rev 43(13):4494–4562CrossRef Hu R, Leung NLC, Tang BZ (2014) AIE macromolecules: syntheses, structures and functionalities. Chem Soc Rev 43(13):4494–4562CrossRef
42.
Zurück zum Zitat Mei J, Hong Y, Lam JWY, Qin A, Tang Y, Tang BZ (2014) Aggregation-induced emission: the whole is more brilliant than the parts. Adv Mater 26(31):5429–5479CrossRef Mei J, Hong Y, Lam JWY, Qin A, Tang Y, Tang BZ (2014) Aggregation-induced emission: the whole is more brilliant than the parts. Adv Mater 26(31):5429–5479CrossRef
43.
Zurück zum Zitat Kwok RTK, Leung CWT, Lam JWY, Tang BZ (2015) Biosensing by luminogens with aggregation-induced emission characteristics. Chem Soc Rev 44(13):4228–4238CrossRef Kwok RTK, Leung CWT, Lam JWY, Tang BZ (2015) Biosensing by luminogens with aggregation-induced emission characteristics. Chem Soc Rev 44(13):4228–4238CrossRef
44.
Zurück zum Zitat Liang J, Tang BZ, Liu B (2015) Specific light-up bioprobes based on AIEgen conjugates. Chem Soc Rev 44(10):2798–2811CrossRef Liang J, Tang BZ, Liu B (2015) Specific light-up bioprobes based on AIEgen conjugates. Chem Soc Rev 44(10):2798–2811CrossRef
45.
Zurück zum Zitat Mei J, Leung NLC, Kwok RTK, Lam JWY, Tang BZ (2015) Aggregation-induced emission: together we shine, united we soar! Chem Rev 115(21):11718–11940CrossRef Mei J, Leung NLC, Kwok RTK, Lam JWY, Tang BZ (2015) Aggregation-induced emission: together we shine, united we soar! Chem Rev 115(21):11718–11940CrossRef
46.
Zurück zum Zitat Wang H, Zhao E, Lam JWY, Tang BZ (2015) AIE luminogens: emission brightened by aggregation. Mater Today 18(7):365–377CrossRef Wang H, Zhao E, Lam JWY, Tang BZ (2015) AIE luminogens: emission brightened by aggregation. Mater Today 18(7):365–377CrossRef
47.
Zurück zum Zitat Zhao Z, He B, Tang BZ (2015) Aggregation-induced emission of siloles. Chem Sci 6(10):5347–5365CrossRef Zhao Z, He B, Tang BZ (2015) Aggregation-induced emission of siloles. Chem Sci 6(10):5347–5365CrossRef
48.
Zurück zum Zitat Yu Y, Feng C, Hong Y, Liu J, Chen S, Ng KM, Luo KQ, Tang BZ (2011) Cytophilic fluorescent bioprobes for long-term cell tracking. Adv Mater 23(29):3298–3302CrossRef Yu Y, Feng C, Hong Y, Liu J, Chen S, Ng KM, Luo KQ, Tang BZ (2011) Cytophilic fluorescent bioprobes for long-term cell tracking. Adv Mater 23(29):3298–3302CrossRef
49.
Zurück zum Zitat Ma H, Qi C, Cheng C, Yang Z, Cao H, Yang Z, Tong J, Yao X, Lei Z (2016) AIE-active tetraphenylethylene cross-linked N-isopropylacrylamide polymer: a long-term fluorescent cellular tracker. ACS Appl Mater Interfaces 8(13):8341–8348CrossRef Ma H, Qi C, Cheng C, Yang Z, Cao H, Yang Z, Tong J, Yao X, Lei Z (2016) AIE-active tetraphenylethylene cross-linked N-isopropylacrylamide polymer: a long-term fluorescent cellular tracker. ACS Appl Mater Interfaces 8(13):8341–8348CrossRef
50.
Zurück zum Zitat Wang Z, Chen S, Lam JWY, Qin W, Kwok RTK, Xie N, Hu Q, Tang BZ (2013) Long-term fluorescent cellular tracing by the aggregates of AIE bioconjugates. J Am Chem Soc 135(22):8238–8245CrossRef Wang Z, Chen S, Lam JWY, Qin W, Kwok RTK, Xie N, Hu Q, Tang BZ (2013) Long-term fluorescent cellular tracing by the aggregates of AIE bioconjugates. J Am Chem Soc 135(22):8238–8245CrossRef
51.
Zurück zum Zitat Qin W, Ding D, Liu J, Yuan WZ, Hu Y, Liu B, Tang BZ (2012) Biocompatible nanoparticles with aggregation-induced emission characteristics as far-red/near-infrared fluorescent bioprobes for in vitro and in vivo imaging applications. Adv Funct Mater 22(4):771–779CrossRef Qin W, Ding D, Liu J, Yuan WZ, Hu Y, Liu B, Tang BZ (2012) Biocompatible nanoparticles with aggregation-induced emission characteristics as far-red/near-infrared fluorescent bioprobes for in vitro and in vivo imaging applications. Adv Funct Mater 22(4):771–779CrossRef
52.
Zurück zum Zitat Ding D, Li K, Qin W, Zhan R, Hu Y, Liu J, Tang BZ, Liu B (2013) Conjugated polymer amplified far-red/near-infrared fluorescence from nanoparticles with aggregation-induced emission characteristics for targeted in vivo imaging. Adv Healthcare Mater 2(3):500–507CrossRef Ding D, Li K, Qin W, Zhan R, Hu Y, Liu J, Tang BZ, Liu B (2013) Conjugated polymer amplified far-red/near-infrared fluorescence from nanoparticles with aggregation-induced emission characteristics for targeted in vivo imaging. Adv Healthcare Mater 2(3):500–507CrossRef
53.
Zurück zum Zitat Li K, Jiang Y, Ding D, Zhang X, Liu Y, Hua J, Feng S-S, Liu B (2011) Folic acid-functionalized two-photon absorbing nanoparticles for targeted MCF-7 cancer cell imaging. Chem Commun 47(26):7323–7325CrossRef Li K, Jiang Y, Ding D, Zhang X, Liu Y, Hua J, Feng S-S, Liu B (2011) Folic acid-functionalized two-photon absorbing nanoparticles for targeted MCF-7 cancer cell imaging. Chem Commun 47(26):7323–7325CrossRef
54.
Zurück zum Zitat Li K, Qin W, Ding D, Tomczak N, Geng J, Liu R, Liu J, Zhang X, Liu H, Liu B, Tang BZ (2013) Photostable fluorescent organic dots with aggregation-induced emission (AIE dots) for noninvasive long-term cell tracing. Scientif Rep 3:1150CrossRef Li K, Qin W, Ding D, Tomczak N, Geng J, Liu R, Liu J, Zhang X, Liu H, Liu B, Tang BZ (2013) Photostable fluorescent organic dots with aggregation-induced emission (AIE dots) for noninvasive long-term cell tracing. Scientif Rep 3:1150CrossRef
55.
Zurück zum Zitat Qin W, Li K, Feng G, Li M, Yang Z, Liu B, Tang BZ (2014) Bright and photostable organic fluorescent dots with aggregation-induced emission characteristics for noninvasive long-term cell imaging. Adv Funct Mater 24(5):635–643CrossRef Qin W, Li K, Feng G, Li M, Yang Z, Liu B, Tang BZ (2014) Bright and photostable organic fluorescent dots with aggregation-induced emission characteristics for noninvasive long-term cell imaging. Adv Funct Mater 24(5):635–643CrossRef
56.
Zurück zum Zitat Gao Y, Feng G, Jiang T, Goh C, Ng L, Liu B, Li B, Yang L, Hua J, Tian H (2015) Biocompatible nanoparticles based on diketo-pyrrolo-pyrrole (DPP) with aggregation-induced red/NIR emission for in vivo two-photon fluorescence imaging. Adv Funct Mater 25(19):2857–2866CrossRef Gao Y, Feng G, Jiang T, Goh C, Ng L, Liu B, Li B, Yang L, Hua J, Tian H (2015) Biocompatible nanoparticles based on diketo-pyrrolo-pyrrole (DPP) with aggregation-induced red/NIR emission for in vivo two-photon fluorescence imaging. Adv Funct Mater 25(19):2857–2866CrossRef
57.
Zurück zum Zitat Shao A, Xie Y, Zhu S, Guo Z, Zhu S, Guo J, Shi P, James TD, Tian H, Zhu W-H (2015) Far-red and near-IR AIE-active fluorescent organic nanoprobes with enhanced tumor-targeting efficacy: shape-specific effects. Angew Chem Int Ed 54(25):7275–7280CrossRef Shao A, Xie Y, Zhu S, Guo Z, Zhu S, Guo J, Shi P, James TD, Tian H, Zhu W-H (2015) Far-red and near-IR AIE-active fluorescent organic nanoprobes with enhanced tumor-targeting efficacy: shape-specific effects. Angew Chem Int Ed 54(25):7275–7280CrossRef
58.
Zurück zum Zitat Geng J, Goh CC, Qin W, Liu R, Tomczak N, Ng LG, Tangde BZ, Liu B (2015) Silica shelled and block copolymer encapsulated red-emissive AIE nanoparticles with 50% quantum yield for two-photon excited vascular imaging. Chem Commun 51(69):13416–13419CrossRef Geng J, Goh CC, Qin W, Liu R, Tomczak N, Ng LG, Tangde BZ, Liu B (2015) Silica shelled and block copolymer encapsulated red-emissive AIE nanoparticles with 50% quantum yield for two-photon excited vascular imaging. Chem Commun 51(69):13416–13419CrossRef
59.
Zurück zum Zitat Geng J, Li K, Ding D, Zhang X, Qin W, Liu J, Tang BZ, Liu B (2012) Lipid-PEG-folate encapsulated nanoparticles with aggregation induced emission characteristics: cellular uptake mechanism and two-photon fluorescence imaging. Small 8(23):3655–3663CrossRef Geng J, Li K, Ding D, Zhang X, Qin W, Liu J, Tang BZ, Liu B (2012) Lipid-PEG-folate encapsulated nanoparticles with aggregation induced emission characteristics: cellular uptake mechanism and two-photon fluorescence imaging. Small 8(23):3655–3663CrossRef
60.
Zurück zum Zitat Ding D, Goh CC, Feng G, Zhao Z, Liu J, Liu R, Tomczak N, Geng J, Tang BZ, Ng LG, Liu B (2013) Ultrabright organic dots with aggregation-induced emission characteristics for real-time two-photon intravital vasculature imaging. Adv Mater 25(42):6083–6088CrossRef Ding D, Goh CC, Feng G, Zhao Z, Liu J, Liu R, Tomczak N, Geng J, Tang BZ, Ng LG, Liu B (2013) Ultrabright organic dots with aggregation-induced emission characteristics for real-time two-photon intravital vasculature imaging. Adv Mater 25(42):6083–6088CrossRef
61.
Zurück zum Zitat Kaiser TE, Wang H, Stepanenko V, Würthner F (2007) Supramolecular construction of fluorescent J-aggregates based on hydrogen-bonded perylene dyes. Angew Chem Int Ed 46(29):5541–5544CrossRef Kaiser TE, Wang H, Stepanenko V, Würthner F (2007) Supramolecular construction of fluorescent J-aggregates based on hydrogen-bonded perylene dyes. Angew Chem Int Ed 46(29):5541–5544CrossRef
62.
Zurück zum Zitat Wang H, Kaiser TE, Uernura S, Würthner F (2008) Perylene bisimide J-aggregates with absorption maxima in the NIR. Chem Commun 10:1181–1183CrossRef Wang H, Kaiser TE, Uernura S, Würthner F (2008) Perylene bisimide J-aggregates with absorption maxima in the NIR. Chem Commun 10:1181–1183CrossRef
63.
Zurück zum Zitat Wang L, Li W, Lu J, Zhao Y-X, Fan G, Zhang J-P, Wang H (2013) Supramolecular nano-aggregates based on bis(pyrene) derivatives for lysosome-targeted cell imaging. J Phys Chem C 117(50):26811–26820CrossRef Wang L, Li W, Lu J, Zhao Y-X, Fan G, Zhang J-P, Wang H (2013) Supramolecular nano-aggregates based on bis(pyrene) derivatives for lysosome-targeted cell imaging. J Phys Chem C 117(50):26811–26820CrossRef
64.
Zurück zum Zitat Yang P-P, Yang Y, Gao Y-J, Wang Y, Zhang J-C, Lin Y-X, Dai L, Li J, Wang L, Wang H (2015) Unprecedentedly high tissue penetration capability of co-assembled nanosystems for two-photon fluorescence imaging in vivo. Adv Optical Mater 3(5):646–651CrossRef Yang P-P, Yang Y, Gao Y-J, Wang Y, Zhang J-C, Lin Y-X, Dai L, Li J, Wang L, Wang H (2015) Unprecedentedly high tissue penetration capability of co-assembled nanosystems for two-photon fluorescence imaging in vivo. Adv Optical Mater 3(5):646–651CrossRef
65.
Zurück zum Zitat Olivier J-H, Widmaier J, Ziessel R (2011) Near-infrared fluorescent nanoparticles formed by self-assembly of lipidic (bodipy) dyes. Chem Eur J 17(42):11709–11714CrossRef Olivier J-H, Widmaier J, Ziessel R (2011) Near-infrared fluorescent nanoparticles formed by self-assembly of lipidic (bodipy) dyes. Chem Eur J 17(42):11709–11714CrossRef
66.
Zurück zum Zitat Choi S, Bouffard J, Kim Y (2014) Aggregation-induced emission enhancement of a meso-trifluoromethyl BODIPY via J-aggregation. Chem Sci 5(2):751–755CrossRef Choi S, Bouffard J, Kim Y (2014) Aggregation-induced emission enhancement of a meso-trifluoromethyl BODIPY via J-aggregation. Chem Sci 5(2):751–755CrossRef
67.
Zurück zum Zitat Xu Z, Liao Q, Wu Y, Ren W, Li W, Liu L, Wang S, Gu Z, Zhang H, Fu H (2012) Water-miscible organic J-aggregate nanoparticles as efficient two-photon fluorescent nano-probes for bio-imaging. J Mater Chem 22(34):17737–17743CrossRef Xu Z, Liao Q, Wu Y, Ren W, Li W, Liu L, Wang S, Gu Z, Zhang H, Fu H (2012) Water-miscible organic J-aggregate nanoparticles as efficient two-photon fluorescent nano-probes for bio-imaging. J Mater Chem 22(34):17737–17743CrossRef
68.
Zurück zum Zitat Hayashi T, Hamachi I (2012) Traceless affinity labeling of endogenous proteins for functional analysis in living cells. Acc Chem Res 45(9):1460–1469CrossRef Hayashi T, Hamachi I (2012) Traceless affinity labeling of endogenous proteins for functional analysis in living cells. Acc Chem Res 45(9):1460–1469CrossRef
69.
Zurück zum Zitat Kubota R, Hamachi I (2015) Protein recognition using synthetic small-molecular binders toward optical protein sensing in vitro and in live cells. Chem Soc Rev 44(13):4454–4471CrossRef Kubota R, Hamachi I (2015) Protein recognition using synthetic small-molecular binders toward optical protein sensing in vitro and in live cells. Chem Soc Rev 44(13):4454–4471CrossRef
70.
Zurück zum Zitat Takaoka Y, Ojida A, Hamachi I (2013) Protein organic chemistry and applications for labeling and engineering in live-cell systems. Angew Chem Int Ed 52(15):4088–4106CrossRef Takaoka Y, Ojida A, Hamachi I (2013) Protein organic chemistry and applications for labeling and engineering in live-cell systems. Angew Chem Int Ed 52(15):4088–4106CrossRef
71.
Zurück zum Zitat Mizusawa K, Takaoka Y, Hamachi I (2012) Specific cell surface protein imaging by extended self-assembling fluorescent turn-on nanoprobes. J Am Chem Soc 134(32):13386–13395CrossRef Mizusawa K, Takaoka Y, Hamachi I (2012) Specific cell surface protein imaging by extended self-assembling fluorescent turn-on nanoprobes. J Am Chem Soc 134(32):13386–13395CrossRef
72.
Zurück zum Zitat Fan G, Lin Y-X, Yang L, Gao F-P, Zhao Y-X, Qiao Z-Y, Zhao Q, Fan Y-S, Chen Z, Wang H (2015) Co-self-assembled nanoaggregates of BODIPY amphiphiles for dual colour imaging of live cells. Chem Commun 51(62):12447–12450CrossRef Fan G, Lin Y-X, Yang L, Gao F-P, Zhao Y-X, Qiao Z-Y, Zhao Q, Fan Y-S, Chen Z, Wang H (2015) Co-self-assembled nanoaggregates of BODIPY amphiphiles for dual colour imaging of live cells. Chem Commun 51(62):12447–12450CrossRef
73.
Zurück zum Zitat Qiao Z-Y, Hou C-Y, Zhao W-J, Zhang D, Yang P-P, Wang L, Wang H (2015) Synthesis of self-reporting polymeric nanoparticles for in situ monitoring of endocytic microenvironmental pH. Chem Commun 51(63):12609–12612CrossRef Qiao Z-Y, Hou C-Y, Zhao W-J, Zhang D, Yang P-P, Wang L, Wang H (2015) Synthesis of self-reporting polymeric nanoparticles for in situ monitoring of endocytic microenvironmental pH. Chem Commun 51(63):12609–12612CrossRef
74.
Zurück zum Zitat Raghupathi KR, Guo J, Munkhbat O, Rangadurai P, Thayumanavan S (2014) Supramolecular disassembly of facially amphiphilic dendrimer assemblies in response to physical, chemical, and biological stimuli. Acc Chem Res 47(7):2200–2211CrossRef Raghupathi KR, Guo J, Munkhbat O, Rangadurai P, Thayumanavan S (2014) Supramolecular disassembly of facially amphiphilic dendrimer assemblies in response to physical, chemical, and biological stimuli. Acc Chem Res 47(7):2200–2211CrossRef
75.
Zurück zum Zitat Amado Torres D, Garzoni M, Subrahmanyam AV, Pavan GM, Thayumanavan S (2014) Protein-triggered supramolecular disassembly: insights based on variations in ligand location in amphiphilic dendrons. J Am Chem Soc 136(14):5385–5399CrossRef Amado Torres D, Garzoni M, Subrahmanyam AV, Pavan GM, Thayumanavan S (2014) Protein-triggered supramolecular disassembly: insights based on variations in ligand location in amphiphilic dendrons. J Am Chem Soc 136(14):5385–5399CrossRef
76.
Zurück zum Zitat Wang H, Zhuang J, Raghupathi KR, Thayumanavan S (2015) A supramolecular dissociation strategy for protein sensing. Chem Commun 51(97):17265–17268CrossRef Wang H, Zhuang J, Raghupathi KR, Thayumanavan S (2015) A supramolecular dissociation strategy for protein sensing. Chem Commun 51(97):17265–17268CrossRef
77.
Zurück zum Zitat Gao Y, Shi J, Yuan D, Xu B (2012) Imaging enzyme-triggered self-assembly of small molecules inside live cells. Nat Commun 3:1033CrossRef Gao Y, Shi J, Yuan D, Xu B (2012) Imaging enzyme-triggered self-assembly of small molecules inside live cells. Nat Commun 3:1033CrossRef
78.
Zurück zum Zitat Gao Y, Berciu C, Kuang Y, Shi J, Nicastro D, Xu B (2013) Probing nanoscale self-assembly of nonfluorescent small molecules inside live mammalian cells. ACS Nano 7(10):9055–9063CrossRef Gao Y, Berciu C, Kuang Y, Shi J, Nicastro D, Xu B (2013) Probing nanoscale self-assembly of nonfluorescent small molecules inside live mammalian cells. ACS Nano 7(10):9055–9063CrossRef
79.
Zurück zum Zitat Dragulescu-Andrasi A, Kothapalli S-R, Tikhomirov GA, Rao J, Gambhir SS (2013) Activatable oligomerizable imaging agents for photoacoustic imaging of furin-like activity in living subjects. J Am Chem Soc 135(30):11015–11022CrossRef Dragulescu-Andrasi A, Kothapalli S-R, Tikhomirov GA, Rao J, Gambhir SS (2013) Activatable oligomerizable imaging agents for photoacoustic imaging of furin-like activity in living subjects. J Am Chem Soc 135(30):11015–11022CrossRef
80.
Zurück zum Zitat Liang G, Ren H, Rao J (2010) A biocompatible condensation reaction for controlled assembly of nanostructures in living cells. Nat Chem 2(1):54–60CrossRef Liang G, Ren H, Rao J (2010) A biocompatible condensation reaction for controlled assembly of nanostructures in living cells. Nat Chem 2(1):54–60CrossRef
81.
Zurück zum Zitat Ye D, Shuhendler AJ, Cui L, Tong L, Tee SS, Tikhomirov G, Felsher DW, Rao J (2014) Bioorthogonal cyclization-mediated in situ self-assembly of small-moleculeprobes for imaging caspase activity in vivo. Nat Chem 6(6):519–526CrossRef Ye D, Shuhendler AJ, Cui L, Tong L, Tee SS, Tikhomirov G, Felsher DW, Rao J (2014) Bioorthogonal cyclization-mediated in situ self-assembly of small-moleculeprobes for imaging caspase activity in vivo. Nat Chem 6(6):519–526CrossRef
82.
Zurück zum Zitat Ye D, Shuhendler AJ, Pandit P, Brewer KD, Tee SS, Cui L, Tikhomirov G, Rutt B, Rao J (2014) Caspase-responsive smart gadolinium-based contrast agent for magnetic resonance imaging of drug-induced apoptosis. Chem Sci 5(10):3845–3852CrossRef Ye D, Shuhendler AJ, Pandit P, Brewer KD, Tee SS, Cui L, Tikhomirov G, Rutt B, Rao J (2014) Caspase-responsive smart gadolinium-based contrast agent for magnetic resonance imaging of drug-induced apoptosis. Chem Sci 5(10):3845–3852CrossRef
83.
Zurück zum Zitat Shi H, Kwok RTK, Liu J, Xing B, Tang BZ, Liu B (2012) Real-time monitoring of cell apoptosis and drug screening using fluorescent light-up probe with aggregation-induced emission characteristics. J Am Chem Soc 134(43):17972–17981CrossRef Shi H, Kwok RTK, Liu J, Xing B, Tang BZ, Liu B (2012) Real-time monitoring of cell apoptosis and drug screening using fluorescent light-up probe with aggregation-induced emission characteristics. J Am Chem Soc 134(43):17972–17981CrossRef
84.
Zurück zum Zitat Yuan Y, Kwok RTK, Tang BZ, Liu B (2014) Targeted theranostic platinum (IV) prodrug with a built-in aggregation-induced emission light-up apoptosis sensor for noninvasive early evaluation of its therapeutic responses in situ. J Am Chem Soc 136(6):2546–2554CrossRef Yuan Y, Kwok RTK, Tang BZ, Liu B (2014) Targeted theranostic platinum (IV) prodrug with a built-in aggregation-induced emission light-up apoptosis sensor for noninvasive early evaluation of its therapeutic responses in situ. J Am Chem Soc 136(6):2546–2554CrossRef
85.
Zurück zum Zitat Han H, Jin Q, Wang Y, Chen Y, Ji J (2015) The rational design of a gemcitabine prodrug with AIE-based intracellular light-up characteristics for selective suppression of pancreatic cancer cells. Chem Commun 51(98):17435–17438CrossRef Han H, Jin Q, Wang Y, Chen Y, Ji J (2015) The rational design of a gemcitabine prodrug with AIE-based intracellular light-up characteristics for selective suppression of pancreatic cancer cells. Chem Commun 51(98):17435–17438CrossRef
86.
Zurück zum Zitat Yuan Y, Zhang C-J, Gao M, Zhang R, Tang BZ, Liu B (2015) Specific light-up bioprobe with aggregation-induced emission and activatable photoactivity for the targeted and image-guided photodynamic ablation of cancer cells. Angew Chem Int Ed 54(6):1780–1786CrossRef Yuan Y, Zhang C-J, Gao M, Zhang R, Tang BZ, Liu B (2015) Specific light-up bioprobe with aggregation-induced emission and activatable photoactivity for the targeted and image-guided photodynamic ablation of cancer cells. Angew Chem Int Ed 54(6):1780–1786CrossRef
87.
Zurück zum Zitat Liang J, Kwok RTK, Shi H, Tang BZ, Liu B (2013) Fluorescent light-up probe with aggregation-induced emission characteristics for alkaline phosphatase sensing and activity study. ACS Appl Mater Interfaces 5(17):8784–8789CrossRef Liang J, Kwok RTK, Shi H, Tang BZ, Liu B (2013) Fluorescent light-up probe with aggregation-induced emission characteristics for alkaline phosphatase sensing and activity study. ACS Appl Mater Interfaces 5(17):8784–8789CrossRef
88.
Zurück zum Zitat Duan Z, Gao Y-J, Qiao Z-Y, Qiao S, Wang Y, Hou C, Wang L, Wang H (2015) pH-Sensitive polymer assisted self-aggregation of bis(pyrene) in living cells in situ with turn-on fluorescence. Nanotechnology 26(35)CrossRef Duan Z, Gao Y-J, Qiao Z-Y, Qiao S, Wang Y, Hou C, Wang L, Wang H (2015) pH-Sensitive polymer assisted self-aggregation of bis(pyrene) in living cells in situ with turn-on fluorescence. Nanotechnology 26(35)CrossRef
89.
Zurück zum Zitat Lin Y-X, Qiao S-L, Wang Y, Zhang R-X, An H-W, Ma Y, Rajapaksha RPYJ, Qiao Z-Y, Wang L, Wang H (2017) An in situ intracellular self-assembly strategy for quantitatively and temporally monitoring autophagy. ACS Nano 11(2):1826–1839CrossRef Lin Y-X, Qiao S-L, Wang Y, Zhang R-X, An H-W, Ma Y, Rajapaksha RPYJ, Qiao Z-Y, Wang L, Wang H (2017) An in situ intracellular self-assembly strategy for quantitatively and temporally monitoring autophagy. ACS Nano 11(2):1826–1839CrossRef
90.
Zurück zum Zitat Carter NA, Grove TZ (2015) Repeat-proteins films exhibit hierarchical anisotropic mechanical properties. Biomacromol 16(3):706–714CrossRef Carter NA, Grove TZ (2015) Repeat-proteins films exhibit hierarchical anisotropic mechanical properties. Biomacromol 16(3):706–714CrossRef
91.
Zurück zum Zitat Feldkamp U, Niemeyer CM (2006) Rational design of DNA nanoarchitectures. Angew Chem Int Ed 45(12):1856–1876CrossRef Feldkamp U, Niemeyer CM (2006) Rational design of DNA nanoarchitectures. Angew Chem Int Ed 45(12):1856–1876CrossRef
92.
Zurück zum Zitat Callmann CE, Barback CV, Thompson MP, Hall DJ, Mattrey RF, Gianneschi NC (2015) Therapeutic enzyme-responsive nanoparticles for targeted delivery and accumulation in tumors. Adv Mater 27(31):4611–4615CrossRef Callmann CE, Barback CV, Thompson MP, Hall DJ, Mattrey RF, Gianneschi NC (2015) Therapeutic enzyme-responsive nanoparticles for targeted delivery and accumulation in tumors. Adv Mater 27(31):4611–4615CrossRef
93.
Zurück zum Zitat Nguyen MM, Carlini AS, Chien M-P, Sonnenberg S, Luo C, Braden RL, Osborn KG, Li Y, Gianneschi NC, Christman KL (2015) Enzyme-responsive nanoparticles for targeted accumulation and prolonged retention in heart tissue after myocardial infarction. Adv Mater 27(37):5547–5552CrossRef Nguyen MM, Carlini AS, Chien M-P, Sonnenberg S, Luo C, Braden RL, Osborn KG, Li Y, Gianneschi NC, Christman KL (2015) Enzyme-responsive nanoparticles for targeted accumulation and prolonged retention in heart tissue after myocardial infarction. Adv Mater 27(37):5547–5552CrossRef
94.
Zurück zum Zitat Moyer TJ, Finbloom JA, Chen F, Toft DJ, Cryns VL, Stupp SI (2014) pH and amphiphilic structure direct supramolecular behavior in biofunctional assemblies. J Am Chem Soc 136(42):14746–14752CrossRef Moyer TJ, Finbloom JA, Chen F, Toft DJ, Cryns VL, Stupp SI (2014) pH and amphiphilic structure direct supramolecular behavior in biofunctional assemblies. J Am Chem Soc 136(42):14746–14752CrossRef
95.
Zurück zum Zitat Matson JB, Navon Y, Bitton R, Stupp SI (2015) Light-controlled hierarchical self-assembly of polyelectrolytes and supramolecular polymers. ACS Macro Lett 4(1):43–47CrossRef Matson JB, Navon Y, Bitton R, Stupp SI (2015) Light-controlled hierarchical self-assembly of polyelectrolytes and supramolecular polymers. ACS Macro Lett 4(1):43–47CrossRef
96.
Zurück zum Zitat Sun H-L, Chen Y, Zhao J, Liu Y (2015) Photocontrolled reversible conversion of nanotube and nanoparticle mediated by -cyclodextrin dimers. Angew Chem Int Ed 54(32):9376–9380CrossRef Sun H-L, Chen Y, Zhao J, Liu Y (2015) Photocontrolled reversible conversion of nanotube and nanoparticle mediated by -cyclodextrin dimers. Angew Chem Int Ed 54(32):9376–9380CrossRef
97.
Zurück zum Zitat Shao H, Parquette JR (2009) Controllable peptide-dendron self-assembly: interconversion of nanotubes and fibrillar nanostructures. Angew Chem Int Ed 48(14):2525–2528CrossRef Shao H, Parquette JR (2009) Controllable peptide-dendron self-assembly: interconversion of nanotubes and fibrillar nanostructures. Angew Chem Int Ed 48(14):2525–2528CrossRef
98.
Zurück zum Zitat An H-W, Qiao S-L, Li L-L, Yang C, Lin Y-X, Wang Y, Qao Z-Y, Wang L, Wang H (2016) Bio-orthogonally Deciphered binary nanoemitters for tumor diagnostics. ACS Appl Mater Interfaces 8(30):19202–19207CrossRef An H-W, Qiao S-L, Li L-L, Yang C, Lin Y-X, Wang Y, Qao Z-Y, Wang L, Wang H (2016) Bio-orthogonally Deciphered binary nanoemitters for tumor diagnostics. ACS Appl Mater Interfaces 8(30):19202–19207CrossRef
99.
Zurück zum Zitat Yang P-P, Zhao X-X, Xu A-P, Wang L, Wang H (2016) Reorganization of self-assembled supramolecular materials controlled by hydrogen bonding and hydrophilic-lipophilic balance. J Mater Chem B 4(15):2662–2668CrossRef Yang P-P, Zhao X-X, Xu A-P, Wang L, Wang H (2016) Reorganization of self-assembled supramolecular materials controlled by hydrogen bonding and hydrophilic-lipophilic balance. J Mater Chem B 4(15):2662–2668CrossRef
100.
Zurück zum Zitat Esler WP, Stimson ER, Ghilardi JR, Lu Y-A, Felix AM, Vinters HV, Mantyh PW, Lee JP, Maggio JE (1996) Point substitution in the central hydrophobic cluster of a human β-Amyloid congener disrupts peptide folding and abolishes plaque competence. Biochemistry 35(44):13914–13921CrossRef Esler WP, Stimson ER, Ghilardi JR, Lu Y-A, Felix AM, Vinters HV, Mantyh PW, Lee JP, Maggio JE (1996) Point substitution in the central hydrophobic cluster of a human β-Amyloid congener disrupts peptide folding and abolishes plaque competence. Biochemistry 35(44):13914–13921CrossRef
101.
Zurück zum Zitat Molla MR, Prasad P, Thayumanavan S (2015) Protein-induced supramolecular disassembly of amphiphilic polypeptide nanoassemblies. J Am Chem Soc 137(23):7286–7289CrossRef Molla MR, Prasad P, Thayumanavan S (2015) Protein-induced supramolecular disassembly of amphiphilic polypeptide nanoassemblies. J Am Chem Soc 137(23):7286–7289CrossRef
102.
Zurück zum Zitat Xu A-P, Yang P-P, Yang C, Gao Y-J, Zhao X-X, Luo Q, Li X-D, Li L-Z, Wang L, Wang H (2016) Bio-inspired metal ions regulate the structure evolution of self-assembled peptide-based nanoparticles. Nanoscale 8(29):14078–14083CrossRef Xu A-P, Yang P-P, Yang C, Gao Y-J, Zhao X-X, Luo Q, Li X-D, Li L-Z, Wang L, Wang H (2016) Bio-inspired metal ions regulate the structure evolution of self-assembled peptide-based nanoparticles. Nanoscale 8(29):14078–14083CrossRef
103.
Zurück zum Zitat Yu YP, Wang Q, Liu YC, Xie Y (2014) Molecular basis for the targeted binding of RGD-containing peptide to integrin αvβ3. Biomaterials 35(5):1667–1675CrossRef Yu YP, Wang Q, Liu YC, Xie Y (2014) Molecular basis for the targeted binding of RGD-containing peptide to integrin αvβ3. Biomaterials 35(5):1667–1675CrossRef
104.
Zurück zum Zitat Craig D, Gao M, Schulten K, Vogel V (2004) Structural insights into how the MIDAS ion stabilizes integrin binding to an RGD peptide under force. Structure 12(11):2049–2058CrossRef Craig D, Gao M, Schulten K, Vogel V (2004) Structural insights into how the MIDAS ion stabilizes integrin binding to an RGD peptide under force. Structure 12(11):2049–2058CrossRef
105.
Zurück zum Zitat Puklin-Faucher E, Vogel V (2009) Integrin activation dynamics between the RGD-binding site and the headpiece hinge. J Biol Chem 284(52):36557–36568CrossRef Puklin-Faucher E, Vogel V (2009) Integrin activation dynamics between the RGD-binding site and the headpiece hinge. J Biol Chem 284(52):36557–36568CrossRef
Metadaten
Titel
Supramolecular Self-assembled Nanomaterials for Fluorescence Bioimaging
verfasst von
Lei Wang
Guo-Bin Qi
Copyright-Jahr
2018
Verlag
Springer Singapore
DOI
https://doi.org/10.1007/978-981-10-6913-0_1

    Marktübersichten

    Die im Laufe eines Jahres in der „adhäsion“ veröffentlichten Marktübersichten helfen Anwendern verschiedenster Branchen, sich einen gezielten Überblick über Lieferantenangebote zu verschaffen.