Skip to main content
Fachgebiete
Automobil + Motoren Bauwesen + Immobilien Business IT + Informatik Elektrotechnik + Elektronik Energie + Nachhaltigkeit Finance + Banking Management + Führung Marketing + Vertrieb Maschinenbau + Werkstoffe Versicherung + Risiko
DE
EN
Bücher
Zeitschriften
Themenseiten
Organisationspsychologie Projektmanagement Marketing Smart Manufacturing
Weitere Formate
Podcasts Webinare Technik Webinare Wirtschaft Kongresse Veranstaltungskalender Awards
Jetzt Einzelzugang starten
Zugang für Unternehmen
Referenzkunden
SLX-Digitalkonferenz: Zukunftswerkstatt 2024

Mehr Umsatz mit Top-Kontakten

Am 7. Mai erfahren Sie, wie Vertriebsteams Leadgenerierung, Leadnurturing und Leadstrategien effizient steuern können.
Erweiterte Suche
Anmelden
nach oben
Colloid and Polymer Science
Erschienen in: Colloid and Polymer Science 1/2017

03.12.2016 | Original Contribution

Surfactant-free poly(methyl methacrylate)/poly(vinylamine) (PMMA/PVAm) amphiphilic core-shell polymer particles

verfasst von: A. Bonnefond, C. Pereira Gomes, J. C. de la Cal, J. R. Leiza

Erschienen in: Colloid and Polymer Science | Ausgabe 1/2017

Einloggen

Aktivieren Sie unsere intelligente Suche, um passende Fachinhalte oder Patente zu finden.

search-config
loading …

Abstract

Surfactant-free emulsion polymerization for the synthesis of poly(methyl methacrylate)/poly(vinylamine) (PMMA/PVAm) amphiphilic core-shell polymer particles is investigated in this work. Particularly, the effect of the PVAm molar mass and the tert-butyl hydroperoxide (TBHP)/PVAm molar ratio on the kinetics of reaction and particle nucleation is studied, and the morphology of the polymer particles carefully analyzed. Interestingly, decreasing the TBHP/PVAm molar ratio leads to faster kinetics of the polymerization reaction. Decreasing the molar mass of PVAm also yields faster kinetics. The morphology of the PMMA/PVAm polymer particles is core-shell like, and the PVAm chains are located at the surface of the polymer particles acting as stabilizer. Thus, the pH affects their morphology and the PVAm chains are fully extended at low pH and hence are swollen by water and have large size, whereas at high pH, the PVAm chains shrink and particle sizes are smaller.
Vorheriger Artikel Development of multiple W/O/W emulsions used in pharmaceutical field: effect of additives and insulin on physicochemical and rheological stability of emulsions
Nächster Artikel Stabilizing silica nanoparticles in high saline water by using ionic surfactants for wettability alteration application

Sie haben noch keine Lizenz? Dann Informieren Sie sich jetzt über unsere Produkte:

Springer Professional "Wirtschaft+Technik"

Online-Abonnement

Mit Springer Professional "Wirtschaft+Technik" erhalten Sie Zugriff auf:

  • über 102.000 Bücher
  • über 537 Zeitschriften

aus folgenden Fachgebieten:

  • Automobil + Motoren
  • Bauwesen + Immobilien
  • Business IT + Informatik
  • Elektrotechnik + Elektronik
  • Energie + Nachhaltigkeit
  • Finance + Banking
  • Management + Führung
  • Marketing + Vertrieb
  • Maschinenbau + Werkstoffe
  • Versicherung + Risiko

Jetzt Wissensvorsprung sichern!

Jetzt informieren

Springer Professional "Technik"

Online-Abonnement

Mit Springer Professional "Technik" erhalten Sie Zugriff auf:

  • über 67.000 Bücher
  • über 390 Zeitschriften

aus folgenden Fachgebieten:

  • Automobil + Motoren
  • Bauwesen + Immobilien
  • Business IT + Informatik
  • Elektrotechnik + Elektronik
  • Energie + Nachhaltigkeit
  • Maschinenbau + Werkstoffe




 

Jetzt Wissensvorsprung sichern!

Jetzt informieren
Literatur
1.
Putnam D (2006) Polymers for gene delivery across length scales. Nat Mater 5:439–451CrossRef
2.
McLachan G, Baker A, Tennat P, Gordon C, Vrettou C, Renwick L, Blundell R, Cheng SH, Scheule RK, Davies L, Painter H, Coles RL, Lawton AE, Mariott C, Gill DR, Hyde SC, Griesenbach U, Alton EWFW, Boyd AC, Porteous DJ, Collie DDS (2007) Optimizing aerosol Gene delivery and expression in the ovine lung. Mol Ther 15:348–354CrossRef
3.
Ho KM, Li WY, Wong CH, Li P (2010) Amphiphilic polymeric particles with core–shell nanostructures: emulsion-based syntheses and potential applications. Colloid Polym Sci 288:1503–1523CrossRef
4.
Li P, Poon YF, Li W, Zhu HY, Yeap SH, Cao Y, Qi X, Zhou C, Lamrani M, Beuerman RW, Kang ET, Mu Y, Li CM, Chang MW, Jan Leong SS, Chan Park MB (2011) A polycationic antimicrobial and biocompatible hydrogel with microbe membrane suctioning ability. Nat Mater 10:149–156CrossRef
5.
Zhou J, Liu J, Cheng CJ, Patel TR, Weller CE, Piepmeier JM, Jiang Z, Saltzman WM (2012) Biodegradable poly(amine-co-ester) terpolymers for targeted gene delivery. Nat Mater 11:82–90CrossRef
6.
Samal SK, Dash M, Vlierbeghe SV, Kaplan DL, Chiellini E, Blitterswijk CV, Moroni L, Dubruel P (2012) Cationic polymers and their therapeutic potential. Chem Soc Rev 41:7147–7194CrossRef
7.
Jayachandran KN, Chatterji PR (1998) Grafted polymeric microspheres: a synthetic approach to structurally well-defined brush polymers. J Macromol Sci Pure Appl Chem A 35:1971–1986CrossRef
8.
Wang Y, Du Q, Hung J (1998) Grafting of poly(ethylene oxide) with Schiff's base end group onto chloromethylated polystyrene via Decker-Forster reaction. Macromol Rapid Comm 19:247–250CrossRef
9.
Edmondson S, Osborne VL, Huck WT (2004) Polymer brushes via surface-initiated polymerizations. Chem Soc Rev 33:14–22CrossRef
10.
Balauff M (2003) Nanoscopic polymer particles with a well-defined surface: synthesis, characterization, and properties. Macromol Chem Phys 204:220–234CrossRef
11.
Kizhakkedathu NJ, Brooks DE (2003) Synthesis of poly(N,N-dimethylacrylamide) brushes from charged polymeric surfaces by aqueous ATRP: effect of surface initiator concentration. Macromolecules 36:591–598CrossRef
12.
D’Agosto F, Hughes R, Charreyre MT, Pichot C, Gilbert RG (2003) Molecular weight and functional end group control by RAFT polymerization of a Bisubstituted acrylamide derivative. Macromolecules 36:621–629CrossRef
13.
Tsuji S, Kawagushi H (2004) Temperature-sensitive hairy particles prepared by living radical graft polymerization. Langmuir 20:2449–2455CrossRef
14.
Lu Y, Wittemann A, Balauff M, Drechsler M (2006) Preparation of polystyrene-poly(N-isopropylacrylamide) (PS-PNIPA) core-shell particles by photoemulsion polymerization. Macromol Rapid Comm 27:1137–1141CrossRef
15.
Balauff M, Lu Y (2007) “Smart” nanoparticles: preparation, characterization and applications. Polymer 48:1815–1823CrossRef
16.
Serizawa T, Cheng MQ, Akashi M (1998) Graft copolymers having hydrophobic backbone and hydrophilic branches. XVIII. Poly(styrene) nanospheres with novel thermosensitive poly(N-vinylisobutyramide)s on their surfaces. J Polym Sci A Polym Chem 36:2581–2587CrossRef
17.
Seriwaza T, Yasunaga S, Akashi M (2001) Synthesis and lectin recognition of polystyrene core−glycopolymer corona nanospheres. Biomacromolecules 2:469–475CrossRef
18.
Ferguson CJ, Hughes RJ, Nguyen D, Pham BTT, Gilbert RG, Serelis AK, Such CH, Hawkett HS (2005) Ab initio emulsion polymerization by RAFT-controlled self-assembly. Macromolecules 38:2191–2204CrossRef
19.
Save M, Manguian M, Chassenieux C, Charleux B (2005) Synthesis by RAFT of amphiphilic block and comblike cationic copolymers and their use in emulsion polymerization for the electrosteric stabilization of latexes. Macromolecules 38:280–289CrossRef
20.
Huang H, Kowalewski T, Remsen EE, Gertzmann R, Wooley KL (1997) Hydrogel-coated glassy nanospheres: a novel method for the synthesis of shell cross-linked knedels. J Am Chem Soc 119:11653–11659CrossRef
21.
Zhang K, Fang H, Shen G, Taylos JSA, Wooley KL (2009) Well-defined cationic shell crosslinked nanoparticles for efficient delivery of DNA or peptide nucleic acids. Proc Am Thor Soc 6:450–457CrossRef
22.
Warren NJ, Armes SP (2014) Polymerization-induced self-assembly of block copolymer nano-objects via RAFT aqueous dispersion polymerization. J Am Chem Soc 136:10174–10185CrossRef
23.
Ratcliffe LPD, McKenzie BE, Le Bouëdec GMD, Williams CN, Brown SL, Armes SP (2015) Polymerization-induced self-assembly of all-acrylic diblock copolymers via RAFT dispersion polymerization in alkanes. Macromolecules 48:8594–8607CrossRef
24.
Sukhorukov GB, Donath E, Davis S, Lichtenfeld H, Caruso F, Popov VI, Mohwald H (1998) Stepwise polyelectrolyte assembly on particle surfaces: a novel approach to colloid design. Polym Adv Technol 9:759–767CrossRef
25.
Caruso F, Mohwald H (1999) Protein multilayer formation on colloids through a stepwise self-assembly technique. J Am Chem Soc 121:6039–6046CrossRef
26.
Li P, Zhu J, Sunintaboon P, Harris F (2002) New route to amphiphilic core−shell polymer nanospheres: graft copolymerization of methyl methacrylate from water-soluble polymer chains containing amino groups. Langmuir 18:8641–8646CrossRef
27.
Li P, Zhu J, Harris F (2002) Amphiphilic core-shell latexes. US Patent 2002/0143081 A1
28.
Zhu J, Li P (2003) Synthesis and characterization of poly(methyl methacrylate)/casein nanoparticles with a well-defined core-shell structure. J Polym Sci A Polym Chem 41:3346–3353CrossRef
29.
Li P, Zhu J, Sunintaboonn P, Harris F (2003) Preparation of latexes with poly(methyl methacrylate) cores and hydrophilic polymer shells containing amino groups. J Dispersion Sci Tecnol 24:607–613CrossRef
30.
Leung MF, Zhu J, Harris FW, Li P (2004) New route to smart core-shell polymeric microgels: synthesis and properties. Macromol Rapid Commun 25:1819–1823CrossRef
31.
Zhu J, Tang A, Law LP, Feng M, Ho KM, Lee DKL, Harris FW, Li P (2005) Amphiphilic core−shell nanoparticles with poly(ethylenimine) shells as potential gene delivery carriers. Bioconjug Chem 16:139–146CrossRef
32.
Feng M, Li P (2006) Amine-containing core-shell nanoparticles as potential drug carriers for intracellular delivery. J Biomed Mater Res Part A 1:184–193
33.
Li W, Li P (2007) Synthesis of well-defined amphiphilic core–shell particles containing amine-rich shells. Macromol Rapid Commun 28:2267–2271CrossRef
34.
Ho KM, Mao X, Gu L, Li P (2008) Facile route to enzyme immobilization: core−shell nanoenzyme particles consisting of well-defined poly(methyl methacrylate) cores and cellulase shells. Langmuir 24:11036–11042CrossRef
35.
Ho KM, Li WY, Lee CH, Yam CH, Gilbert RG, Li P (2010) Mechanistic study of the formation of amphiphilic core–shell particles by grafting methyl methacrylate from polyethylenimine through emulsion polymerization. Polymer 51:3512–3519CrossRef
36.
Pelton R (2014) Polyvinylamine: a tool for engineering interfaces. Langmuir 30:15373–15382CrossRef
37.
Krasemann L, Toutianoush A, Tieke B (2001) Self-assembled polyelectrolyte multilayer membranes with highly improved pervaporation separation of ethanol/water mixtures. J Membr Sci 181:221–228CrossRef
38.
Itagaki T, Shiraga M, Sawayama S, Satoh Z (1991) Vinylamine copolymer flocculating agent and paper strength increasing agent using the same as well as process for producing the same. US Patent EP 0251182(B1)
39.
Zataray J, Aguirre A, de la Cal JC, Leiza JR (2014) Polymerization of N-vinyl formamide in aqueous phase: synthesis of nanoparticles by inverse Microemulsion polymerization and surfactant free emulsion polymerization. Macromol Symp 333:80–92CrossRef
40.
Nebel RL, Saacke RG (1994) Technology and applications for encapsulated spermatozoa. Biotechnol Adv 12:41–48CrossRef
41.
Voigt I, Simon F, Komber H, Jacobasch HJ, Spange S (2000) Controlled synthesis of stable poly(vinyl formamide-co-vinyl amine)/silica hybrid particles by interfacial post-cross-linking reactions. Colloid Polym Sci 278:48–56CrossRef
42.
Voigt I, Simon F, Kathrin E, Spange S (2001) Structure and surface polarity of poly(vinylformamide-co-vinylamine) (PVFA-co-PVAm)/silica hybrid materials. Langmuir 17:3080–3086CrossRef
43.
Budcatariu F, Simon F, Spange S, Schwarz S, Dragan S (2004) Adsorption of poly(vinyl formamide-co-vinyl amine) onto silica particle surfaces and stability of the formed hybrid materials. Macromol Symp 210:219–228CrossRef
44.
Seifert S, Simon F, Baumann G, Hietschold M, Seifert A, Spange S (2011) Adsorption of poly(vinyl formamide-co-vinyl amine) (PVFA-co-PVAm) polymers on zinc, zinc oxide, iron, and iron oxide surfaces. Langmuir 27:14279–14289CrossRef
45.
Seifert S, Höhne S, Simon F, Hanzelmann C, Winkler R, Schmidt T, Frenzel R, Uhlmann P, Spange S (2012) Adsorption of poly(vinylformamide-co-vinylamine) polymers (PVFA-co-PVAm) on copper. Langmuir 28:14935–14943CrossRef
46.
Kasyanenko N, Afasieva D, Drikinsky B, Mukhin D, Nazarova O, Panarin E (2007) DNA interaction with synthetic polymers in solution. Struct Chem 18:519–525CrossRef
47.
Zataray J, Agirre A, Carretero P, Meabe L, De la Cal JC, Leiza JR (2015) Characterization of poly(N-vinyl formamide) by size exclusion chromatography–multiangle light scattering and asymmetric-flow field-flow fractionation–multiangle light scattering. J Appl Polym Sci 132:42434CrossRef
48.
Elizalde O, Arzamendi G, Leiza JR, Asua JM (2004) Seeded semibatch emulsion copolymerization of n-butyl acrylate and methyl methacrylate. Ind Eng Chem Res 43:7401–7409CrossRef
49.
Katchalsky A, Mazur J, Spitnik P (1957) SECTION II: polybase properties of polyvinylamine. J Polym Sci 23:513–532CrossRef
50.
Kirwan LJ, Papastavrou G, Borcovec M, Behrens SH (2004) Imaging the coil-to-globule conformational transition of a weak polyelectrolyte by tuning the polyelectrolyte charge density. Nanoletters 1:149–152CrossRef
51.
(2015) Cationic polymers in regenerative medicine. In: Samal SK, Dubruel P (eds) RSC polymer chemistry series n° 13, Cambridge, UK
52.
Kasyanenko N, Afanasieva D, Dribinsky B, Mukhin D, Nazarova O, Panarin E (2007) DNA interaction with synthetic polymers in solution. Struct Chem 18(4):519–525CrossRef
53.
Ibraheen D, Elaissari A, Fessi H (2014) Gene therapy and DNA delivery systems. International J Pharmaceutics 459:70–83CrossRef
54.
Khondee S, Yakovleva T, Berkland C (2010) Low charge polyninylamine nanogels offers sustained low-level gene expression. J Appl Polym Sci 118:1921–1932
Metadaten
Titel
Surfactant-free poly(methyl methacrylate)/poly(vinylamine) (PMMA/PVAm) amphiphilic core-shell polymer particles
verfasst von
A. Bonnefond
C. Pereira Gomes
J. C. de la Cal
J. R. Leiza
Publikationsdatum
03.12.2016
Verlag
Springer Berlin Heidelberg
Erschienen in
Colloid and Polymer Science / Ausgabe 1/2017
Print ISSN: 0303-402X
Elektronische ISSN: 1435-1536
DOI
https://doi.org/10.1007/s00396-016-3985-5

Weitere Artikel der Ausgabe 1/2017

Colloid and Polymer Science 1/2017 Zur Ausgabe

Original Contribution

The influence of molecular weight of siloxane macromere on phase separation morphology, oxygen permeability, and mechanical properties in multicomponent silicone hydrogels

Original Contribution

A practical comparison of photon correlation and cross-correlation spectroscopy in nanoparticle and microparticle size evaluation

Original Contribution

pH-responsive release of paclitaxel from hydrazone-containing biodegradable micelles

Erratum

Erratum to: The apparently anomalous effects of surfactants on interfacial tension in the IBA/water system near its upper critical solution temperature

Original Contribution

Molecular connectivity indices for modeling the critical micelle concentration of cationic (chloride) Gemini surfactants

Original Contribution

Numerical simulation of optical dispersion, group velocity, and waveguide properties of gold and silver nanocolloids and hybrids

Premium Partner

    Marktübersichten

    Die im Laufe eines Jahres in der „adhäsion“ veröffentlichten Marktübersichten helfen Anwendern verschiedenster Branchen, sich einen gezielten Überblick über Lieferantenangebote zu verschaffen. 

    Zur Marktübersicht
    Bildnachweise