Skip to main content
Fachgebiete
Automobil + Motoren Bauwesen + Immobilien Business IT + Informatik Elektrotechnik + Elektronik Energie + Nachhaltigkeit Finance + Banking Management + Führung Marketing + Vertrieb Maschinenbau + Werkstoffe Versicherung + Risiko
DE
EN
Bücher
Zeitschriften
Themenseiten
Organisationspsychologie Projektmanagement Marketing Smart Manufacturing
Weitere Formate
Podcasts Webinare Technik Webinare Wirtschaft Kongresse Veranstaltungskalender Awards
Jetzt Einzelzugang starten
Zugang für Unternehmen
Referenzkunden
SLX-Digitalkonferenz: Zukunftswerkstatt 2024

Mehr Umsatz mit Top-Kontakten

Am 7. Mai erfahren Sie, wie Vertriebsteams Leadgenerierung, Leadnurturing und Leadstrategien effizient steuern können.
Erweiterte Suche
Anmelden
nach oben
Journal of Materials Science
Erschienen in: Journal of Materials Science 15/2017

22.02.2017 | In Honor of Larry Hench

Synthesis and dissolution behaviour of CaO/SrO-containing sol–gel-derived 58S glasses

verfasst von: Anthony L. B. Maçon, Sungho Lee, Gowsihan Poologasundarampillai, Toshihiro Kasuga, Julian R. Jones

Erschienen in: Journal of Materials Science | Ausgabe 15/2017

Einloggen

Aktivieren Sie unsere intelligente Suche, um passende Fachinhalte oder Patente zu finden.

search-config
loading …

Abstract

The effect of the substitution of strontium for calcium in the tertiary the SiO2–CaO–P2O5 sol–gel bioactive glass 58S (60SiO2·36CaO·4P2O5, mol%) on its structure and its chemical durability on soaking in simulated body fluids was investigated. 58S was selected as a starting composition, and substitution for calcium was carried out from 0 to 100% with an increment of 25%. A novel phosphate source of diethylphosphatoethyltriethoxysilane, which consists of Si and P connected with ethylene group, was used in this work. XRD and FTIR showed that the gels obtained following drying at 130 °C had a typical sol–gel structure, where a continuous amorphous silica gel network and surface bound mineral salts of Ca(NO3)2 and Sr(NO3)2. Once the gels were heat stabilised to decompose nitrates and incorporate the cations into the network, samples containing Sr formed a strontium silicate crystalline phase. With increasing levels of Sr in the composition, the overall crystallinity of the glass–ceramic increased, while, at the maximum substitution of 100% SrO, macroscopic phase separation was observed, characterised by needle-like crystals of strontium apatite (Sr5(PO4)3OH) and strontium silicate (Sr2SiO4) phases in addition to amorphous regions. Dissolution experiments in Tris-buffered solution showed Sr successfully released into the media even though it existed as a crystalline phase in the glass–ceramic. Further, the glass–ceramics induced nucleation and growth of carbonated hydroxyapatite (HA) on their surface suggesting potential bioactivity of the materials. At higher substitutions (75 and 100% SrO for CaO), HA nucleation was not found to occur this may have been due to low amount of phosphate released from the original glass–ceramic as a result of it being locked up in the strontium apatite phase.
Vorheriger Artikel Cerium-doped bioactive 45S5 glasses: spectroscopic, redox, bioactivity and biocatalytic properties
Nächster Artikel Influence of strontium for calcium substitution on the glass–ceramic network and biomimetic behavior in the ternary system SiO2–CaO–MgO

Sie haben noch keine Lizenz? Dann Informieren Sie sich jetzt über unsere Produkte:

Springer Professional "Wirtschaft+Technik"

Online-Abonnement

Mit Springer Professional "Wirtschaft+Technik" erhalten Sie Zugriff auf:

  • über 102.000 Bücher
  • über 537 Zeitschriften

aus folgenden Fachgebieten:

  • Automobil + Motoren
  • Bauwesen + Immobilien
  • Business IT + Informatik
  • Elektrotechnik + Elektronik
  • Energie + Nachhaltigkeit
  • Finance + Banking
  • Management + Führung
  • Marketing + Vertrieb
  • Maschinenbau + Werkstoffe
  • Versicherung + Risiko

Jetzt Wissensvorsprung sichern!

Jetzt informieren

Springer Professional "Technik"

Online-Abonnement

Mit Springer Professional "Technik" erhalten Sie Zugriff auf:

  • über 67.000 Bücher
  • über 390 Zeitschriften

aus folgenden Fachgebieten:

  • Automobil + Motoren
  • Bauwesen + Immobilien
  • Business IT + Informatik
  • Elektrotechnik + Elektronik
  • Energie + Nachhaltigkeit
  • Maschinenbau + Werkstoffe




 

Jetzt Wissensvorsprung sichern!

Jetzt informieren
Anhänge
Nur mit Berechtigung zugänglich
Literatur
1.
Jones JR (2013) Review of bioactive glass: from Hench to hybrids. Acta Biomater 9:4457–4486CrossRef
2.
Li R, Clark AE, Hench LL (1991) An investigation of bioactive glass powders by sol-gel processing. J Appl Biomater 2:231CrossRef
3.
Hoppe A, Mourino V, Boccaccini AR (2013) Therapeutic inorganic ions in bioactive glasses to enhance bone formation and beyond. Biomater Sci 1:254–256CrossRef
4.
Hoppe A, Güldal NS, Boccaccini AR (2011) A review of the biological response to ionic dissolution products from bioactive glasses and glass-ceramics. Biomaterials 32:2757–2774CrossRef
5.
Thompson KH, Orvig C (2003) Boon and bane of metal ions in medicine. Science 300:936–939CrossRef
6.
Henstock JR, Canham LT, Anderson SI (2015) Silicon: the evolution of its use in biomaterials. Acta Biomater 11:17–26CrossRef
7.
Mladenović Ž, Johansson A, Willman B, Shahabi K, Björn E, Ransjö M (2014) Soluble silica inhibits osteoclast formation and bone resorption in vitro. Acta Biomater 10:406–418CrossRef
8.
Li H, Chang J (2013) Bioactive silicate materials stimulate angiogenesis in fibroblast and endothelial cell co-culture system through paracrine effect. Acta Biomater 9:6981–6991CrossRef
9.
Reffitt DM, Ogston N, Jugdaohsingh R et al (2003) Orthosilicic acid stimulates collagen type 1 synthesis and osteoblastic differentiation in human osteoblast-like cells in vitro. Bone 32:127–135CrossRef
10.
Julien M, Magne D, Masson M et al (2007) Phosphate stimulates matrix Gla protein expression in chondrocytes through the extracellular signal regulated kinase signaling pathway. Endocrinology 148:530–537CrossRef
11.
Julien M, Khoshniat S, Lacreusette A et al (2009) Phosphate-dependent regulation of MGP in osteoblasts: role of ERK1/2 and Fra-1. J Bone Miner Res 24:1856–1868CrossRef
12.
Marie PJ (2010) The calcium-sensing receptor in bone cells: a potential therapeutic target in osteoporosis. Bone 46:571–576CrossRef
13.
Valerio P, Pereira MM, Goes AM, Leite MF (2009) Effects of extracellular calcium concentration on the glutamate release by bioactive glass (BG60S) preincubated osteoblasts. Biomed Mater 4:045011CrossRef
14.
Marie PJ, Ammann P, Boivin G, Rey C (2001) Mechanisms of action and therapeutic potential of strontium in bone. Calcif Tissue Int 69:121–129CrossRef
15.
Marie PJ (2007) Strontium ranelate: new insights into its dual mode of action. Bone 40:S5–S8CrossRef
16.
Chattopadhyay N, Quinn SJ, Kifor O, Ye C, Brown EM (2007) The calcium-sensing receptor (CaR) is involved in strontium ranelate-induced osteoblast proliferation. Biochem Pharmacol 74:438–447CrossRef
17.
Barbara A, Delannoy P, Denis BG, Marie PJ (2004) Normal matrix mineralization induced by strontium ranelate in MC3T3-E1 osteogenic cells. Metabolism 53:532–537CrossRef
18.
Autefage H, Gentleman E, Littmann E, Hedegaard MAB, Von Erlach T, O’Donnell M, Burden FR, Winkler DA, Stevens MM (2015) Sparse feature selection methods identify unexpected global cellular response to strontium-containing materials. PNAS 112:4280–4285CrossRef
19.
Takahashi N, Sasaki T, Tsouderos Y, Suda T (2003) S 12911-2 inhibits osteoclastic bone resorption in vitro. J Bone Miner Res 18:1082–1087CrossRef
20.
Lao J, Jallot E, Nedelec J-M (2008) Strontium-delivering glasses with enhanced bioactivity: a new biomaterial for antiosteoporotic applications? Chem Mater 20:4969–4973CrossRef
21.
Lao J, Nedelec JM, Moretto P, Jallot E (2008) Micro-PIXE–RBS methods highlighting the influence of phosphorus on the in vitro bioactivity of sol–gel derived glass particles in the SiO2–CaO–P2O5 system. Nucl. Instrum. Meth. B 66:2412–2417CrossRef
22.
Kim IY, Towler MR, Wren A, Ohtsuki C (2009) Fabrication of spherical CaO–SrO–ZnO–SiO2 particles by sol–gel processing. J Mater Sci Mater Med 20:2267–2273CrossRef
23.
Isaac J, Nohra J, Lao J et al (2011) Effects of strontium-doped bioactive glass on the differentiation of cultured osteogenic cells. Eur Cells Mater 21:130–143CrossRef
24.
Bonhomme C, Gervais C, Folliet N et al (2012) 87Sr solid-state NMR as a structurally sensitive tool for the investigation of materials: antiosteoporotic pharmaceuticals and bioactive glasses. J Am Chem Soc 134:12611–12628CrossRef
25.
Lao J, Nedelec JM, Jallot E (2009) New strontium-based bioactive glasses: physicochemical reactivity and delivering capability of biologically active dissolution products. J Mater Chem 19:2940–2949CrossRef
26.
Hesaraki S, Gholami M, Vazehrad S, Shahrabi S (2010) The effect of Sr concentration on bioactivity and biocompatibility of sol–gel derived glasses based on CaO–SrO–SiO2–P2O5 quaternary system. Mater Sci Eng C 30:383–390CrossRef
27.
Zhu Y, Li X, Yang J, Wang S, Gao H, Hanagata N (2011) Composition-structure-property relationships of the CaO–MxOy–SiO2–P2O5 (M = Zr, Mg, Sr) mesoporous bioactive glass (MBG) scaffolds. J Mater Chem 21:9208–9218CrossRef
28.
Taherkhani S, Moztarzadeh F, Mozafari M, Lotfibakhshaiesh N (2012) Sol–gel synthesis and characterization of unexpected rod-like crystal fibers based on SiO2–(1-x)CaO–xSrO–P2O5 dried-gel. J Non–Cryst Solids 358:342–348CrossRef
29.
Wu C, Zhou Y, Lin C, Chang J, Xiao Y (2012) Strontium-containing mesoporous bioactive glass scaffolds with improved osteogenic/cementogenic differentiation of periodontal ligament cells for periodontal tissue engineering. Acta Biomater 8:3805–3815CrossRef
30.
Zhang Y, Wei L, Chang J et al (2013) Strontium-incorporated mesoporous bioactive glass scaffolds stimulating in vitro proliferation and differentiation of bone marrow stromal cells and in vivo regeneration of osteoporotic bone defects. J Mater Chem B 1:5711–5722CrossRef
31.
Dziadek M, Zagrajczuk B, Menaszek E, Wegrzynowicz A, Pawlik J, Cholewa-Kowalska K (2016) Gel-derived SiO2–CaO–P2O5 bioactive glasses and glass-ceramics modified by SrO addition. Ceram Int 42:5842–5857CrossRef
32.
Taherkhani S, Moztarzadeh F (2016) Influence of strontium on the structure and biological properties of sol–gel-derived mesoporous bioactive glass (MBG) powder. J Sol–Gel Sci Technol 78:539–549CrossRef
33.
Saravanapavan P, Hench LL (2003) Mesoporous calcium silicate glasses. I Synthesis. J Non–Cryst Solids 318:1–13CrossRef
34.
Maçon ALB, Kim TB, Valliant EM et al (2015) A unified in vitro evaluation for apatite-forming ability of bioactive glasses and their variants. J Mater Sci Mater Med 26:1–10CrossRef
35.
Kokubo T, Kushitani H, Sakka S, Kitsugi T, Yamamuro T (1990) Solutions able to reproduce in vivo surface-structure changes in bioactive glass-ceramic A-W3. J Biomed Mater Res 24:721–734CrossRef
36.
Aguiar H, Serra J, González P, León B (2009) Structural study of sol–gel silicate glasses by IR and Raman spectroscopies. J Non–Cryst Solids 355:475–480CrossRef
37.
Sepulveda P, Jones JR, Hench LL (2001) Characterization of melt-derived 45S5 and sol–gel-derived 58S bioactive glasses. J Biomed Mater Res 58:734–740CrossRef
38.
Mozafari M, Moztarzadeh F, Rabiee M et al (2010) Development of macroporous nanocomposite scaffolds of gelatin/bioactive glass prepared through layer solvent casting combined with lamination technique for bone tissue engineering. Ceram Int 36:2431–2439CrossRef
39.
Irish DE, Walrafen GE (1967) Raman and infrared spectral studies of aqueous calcium nitrate solutions. J Chem Phys 46:378–384CrossRef
40.
Goebbert DJ, Garand E, Wende T et al (2009) Infrared spectroscopy of the microhydrated nitrate ions NO3 −(H2O)1−6. J Phys Chem A 113:7584–7592CrossRef
41.
Lin S, Ionescu C, Pike KJ, Smith ME, Jones JR (2009) Nanostructure evolution and calcium distribution in sol–gel derived bioactive glass. J Mater Chem 19:1276–1282CrossRef
42.
Yamane M, Kojima T (1981) Low temperature synthesis of non-crystalline solids of the system SrO–SiO2. J Non-Cryst Solids 44:181–190CrossRef
43.
Brinker CJ, Scherer GW (1990) Sol-gel science: the physics and chemistry of sol–gel processing. Academic Press, San Diego
44.
Zhuravlev LT (2000) The surface chemistry of amorphous silica. Zhuravlev model. Colloids Surf A: physicochem Eng. Aspects 173:1–38CrossRef
45.
Sepulveda P, Jones JR, Hench LL (2002) In vitro dissolution of melt-derived 45S5 and sol–gel-derived 58S bioactive glasses. J Biomed Mater Res 61:301–311CrossRef
46.
Paluszkiewicz C, Blażewicz M, Podporska J, Gumuła T (2008) Nucleation of hydroxyapatite layer on wollastonite material surface: FTIR studies. Vib Spectrosc 48:263–268CrossRef
47.
González B, Colilla M, Vallet-Regí M (2013) Design of in vitro bioactive hybrid materials from the first generation of amine dendrimers as nanobuilding blocks. Chem Eur J 19:4883–4895CrossRef
48.
Maçon ALB, Jacquemin M, Page SJ et al (2017) Lithium-silicate sol–gel bioactive glass and the effect of lithium precursor on structure–property relationships. J Sol–gel Sci Technol 81(1):84–94CrossRef
49.
Kokubo T, Takadama H (2006) How useful is SBF in predicting in vivo bone bioactivity? Biomaterials 27:2907–2915CrossRef
50.
Hesaraki S, Alizadeh M, Nazarian H, Sharifi D (2010) Physico-chemical and in vitro biological evaluation of strontium/calcium silicophosphate glass. J Mater Sci Mater Med 21:695–705CrossRef
51.
Shahrabi S, Hesaraki S, Moemeni S, Khorami M (2011) Structural discrepancies and in vitro nanoapatite formation ability of sol–gel derived glasses doped with different bone stimulator ions. Ceram Int 37:2737–2746CrossRef
52.
Fredholm YC, Karpukhina N, Brauer DS, Jones JR, Law RV, Hill RG (2012) Influence of strontium for calcium substitution in bioactive glasses on degradation, ion release and apatite formation. J R Soc Interface 9:880–889CrossRef
53.
Padilla S, Román J, Carenas A, Vallet-Reg M (2005) The influence of the phosphorus content on the bioactivity of sol–gel glass ceramics. Biomaterials 26:475–483CrossRef
Metadaten
Titel
Synthesis and dissolution behaviour of CaO/SrO-containing sol–gel-derived 58S glasses
verfasst von
Anthony L. B. Maçon
Sungho Lee
Gowsihan Poologasundarampillai
Toshihiro Kasuga
Julian R. Jones
Publikationsdatum
22.02.2017
Verlag
Springer US
Erschienen in
Journal of Materials Science / Ausgabe 15/2017
Print ISSN: 0022-2461
Elektronische ISSN: 1573-4803
DOI
https://doi.org/10.1007/s10853-017-0869-0

Weitere Artikel der Ausgabe 15/2017

Journal of Materials Science 15/2017 Zur Ausgabe

In Honor of Larry Hench

Effects of boron oxide substitution on the structure and bioactivity of SrO-containing bioactive glasses

In Honor of Larry Hench

Tough and strong porous bioactive glass-PLA composites for structural bone repair

In Honor of Larry Hench

Osteoblast-like cell responses to silicate ions released from 45S5-type bioactive glass and siloxane-doped vaterite

In Honor of Larry Hench

Bioactive glass coating on gelatin scaffolds at ambient temperature: easy route to make polymer scaffolds become bioactive

In Honor of Larry Hench

Influence of strontium for calcium substitution on the glass–ceramic network and biomimetic behavior in the ternary system SiO2–CaO–MgO

In Honor of Larry Hench

Hybrid sol–gel inorganic/gelatin porous fibres via solution blow spinning

Premium Partner

    Marktübersichten

    Die im Laufe eines Jahres in der „adhäsion“ veröffentlichten Marktübersichten helfen Anwendern verschiedenster Branchen, sich einen gezielten Überblick über Lieferantenangebote zu verschaffen. 

    Zur Marktübersicht
    Bildnachweise