2015 | OriginalPaper | Buchkapitel
The Correlation between Peripheral Nerve Conduction Study Parametersand Level of Urinary Albumin Excretionin Diabetic Patients
verfasst von : Tran Vu Hoang Duong, Le Quoc Tuan, Nguyen Thi Le
Erschienen in: 5th International Conference on Biomedical Engineering in Vietnam
Aktivieren Sie unsere intelligente Suche, um passende Fachinhalte oder Patente zu finden.
Wählen Sie Textabschnitte aus um mit Künstlicher Intelligenz passenden Patente zu finden. powered by
Markieren Sie Textabschnitte, um KI-gestützt weitere passende Inhalte zu finden. powered by
Diabetic kidney disease (DKD) is the most common cause of end-stage renal disease (ESRD). The incidence of diabetes worldwide is increasing, hence the incidence ofDKDis also increasing.Several previous studies suggested that there may be a relationship between appearance of diabetic peripheral neuropathy (DPN) and impairment of kidney function.
The primary aim of this study was to evaluate the correlation between peripheral nerve conduction study parameters and urinary albumin excretion (UAE) level in diabetic patients. This is a cross-sectional studyperformed in 37 patients with diabetes. After the study, we identified asignificantnegative correlation between level of UAE and action potential (AP), and between level of UAE and nerve conduction velocity (NCV) of motor nerves (R = - 0.33 to R = - 0.65, p < 0.05). We also found asignificantnegative correlation between level of UAE and NCV ((R = - 0.36 to R = - 0.48, p < 0.05), and a significantpositive correlation between level of UAE and DSL (R = 0.37 to R = 0.74, p < 0.05) of sensory nerves.
Our results suggested that the presence of microvascular diabetic complications aresimultaneous, and the earliest presence is the DPN, especially abnormal NCSparameters. This could be a recommendation for the endocrinologist and nephrologist in early detection and treatment of DKD. We suggest that the peripheral NCS should be routinelyscreened for microvascular complications in diabetic patients.