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Erschienen in:
Plagues, Epidemics and Pandemics Kapitel lesen Erstes Kapitel lesen

2020 | OriginalPaper | Buchkapitel

The Emerging Threat of Ebola

verfasst von : Michelle LaBrunda, Naushad Amin

Erschienen in: Global Health Security

Verlag: Springer International Publishing

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Abstract

Ebola is one of the deadliest infectious disease of the modern era. Over 50% of those infected die. Prior to 1976, the disease was unknown. No one knows exactly where it came from, but it is postulated that a mutation in an animal virus allowed it to jump species and infect humans. In 1976 simultaneous outbreaks of Ebola occurred in what is now South Sudan and the Democratic Republic of the Congo (DRC). For 20 years, only sporadic cases were seen, but in 1995 a new outbreak occurred killing hundreds in the DRC. Since that time the frequency of these outbreaks has been increasing. It is uncertain why this is occurring, but many associate it with increasing human encroachment into forested areas bringing people and animals into more intimate contact and increased mobility of previously remote population. This chapter will navigate Ebola in the context of global health and security.
There are multiple objectives of this chapter. First is to provide a basic understanding of Ebola disease processes and outbreak patterns. Second, is to explore the interplay between social determinants of health and Ebola. The role of technology in spreading Ebola outbreaks will be explained as will Ebola’s potential as a bioweapon. Readers will gain understanding of the link between environmental degradation and Ebola outbreaks.
This chapter will be divided into five main sections. These are (1) a case study; (2) Ebola Disease process; (3) Social determinants of health and Ebola; (4) Ebola in the modern era, and (5) the link between Ebola and environmental degradation.

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Vorheriges Kapitel Global Health Biosecurity in a Vulnerable World – An Evaluation of Emerging Threats and Current Disaster Preparedness Strategies for the Future
Nächstes Kapitel Natural and Manmade Disasters: Vulnerable Populations
Literatur
1.
2.
Assessment of the Risk of Ebola Virus Transmission from Bodily Fluids and Fomites (2007) J Infect Dis 196(S-2):S142–S147
3.
4.
Baron R, McCormick J, Zubeir O (1983) Ebola virus disease in southern Sudan: hospital dissemination and intrafamilial spread. Bull World Health Organ 61(6):997–1003
5.
Bausch D, Towner J, Dowell S, Kaducu F, Lukwiya M, Sanchez A et al (2007) Assessment of the risk of Ebola virus transmission from bodily fluids and fomites. J Infect Dis 196(Suppl 2):S142–S147CrossRef
6.
Beeching N, Dance D, Miller A, Spencer R (2002) Biological warfare and bioterrorism. BMP 324:336CrossRef
7.
8.
Bonwitt J, Dawson M, Kandeh M, Ansumana R, Sahr F, Brown H, Kelly A (2018) Unintended consequences of the Bushmeat Ban in West Africa during the 2013–2016 Ebola virus disease epidemic. Soc Sci Med 200:166CrossRef
9.
10.
Brandt A, Oria O, Kallon M, Bazzano AN, Alessandra N (2017) Infant feeding policy and programming during the 2014–2015 Ebola virus disease outbreak in Sierra Leone. Glob Health: Sci Pract 5(3):507–515
11.
Bray M, Mahanty S (2003) Ebola hemorrhagic fever and septic shock. J Infect Dis 188:1613–1617CrossRef
12.
Breman J, Heymann D, Lloyd G, McCormick J, Miatudila M, Murphy F et al (2016) Discovery and description of Ebola Zaire virus in 1976 and relevance to the West African epidemic during 2013–2016. J Infect Dis 214(suppl 3):S93–S101CrossRef
13.
Briand S, Bertherat E, Cox P, Formenty P, Kieny M-P, Myhre J et al (2014) The international Ebola emergency. N Engl J Med 371:1180–1183CrossRef
14.
15.
Bukuluki P, Mpyangu C (2014) The African conception of sacrifice and its relationship with child sacrifice. Int Lett Soc Humanist Sci 30(1):12–21
16.
17.
Bwaka M, Bonnet M, Calain P, Colebunders R, De Roo A, Guimard Y, Van den Enden E (1999) Ebola hemorrhagic fever in Kikwit, Democratic Republic of the Congo: clinical observations in 103 patients. J Infect Dis 179(Suppl 1):S1–S7CrossRef
18.
19.
20.
Cenciarelli o, Gabbarini V, Pietropaoli S, Malizia A, Tamburrini A, Ludovici G, Bellecci C (2015) Viral bioterrorism: learning the lesson of Ebola virus in West Africa. Virus Res 210:318–326CrossRef
21.
22.
23.
24.
25.
26.
27.
Cherfow D, Nath A, Suffiredini A, Danner R, Reich D, Bishop R et al (2016) Severe meningoencephalitis in a case of Ebola virus disease: a case report. Ann Intern Med 165(4):301CrossRef
28.
Christie A, Davies-Wayne G, Cordier-Lassalle T, Blackley D, Laney A, Williams D et al (2015) Possible sexual transmission of Ebola virus – Liberia, 2015. Morb Mortal Wkly Rep 64(17):479
29.
Chughtai A, Barnes M, MacIntyre C (2016) Persistence of Ebola virus in various body fluids during convalescence: evidence and implications for disease transmission and control. Epidemiol Infect 155(8):1652–1660CrossRef
30.
31.
32.
de Greslan T, Billhot M, Rousseau C, Mac Nab C, Karowski L, Cournac J, Cellarier G (2016) Ebola virus-related encephalitis. Clin Infect Dis 63(8):1076–1078CrossRef
33.
De Nys H, Kingebeni P, Keita A, Butel C, Guillaume T, Villabona-Areana C-J, Peeters M (2018) Survey of Ebola viruses in frugivorous and insectivorous bats in Guinea, Cameroon, and the Democratic Republic of the Congo, 2015–2017. Emerg Infect Dis. https://​doi.​org/​10.​3201/​eid2412.​180740
34.
35.
36.
37.
38.
39.
40.
41.
42.
Fang L-Q, Yang Y, Jiang J-F, Yao H-W, Kargbo D, Jia B-G et al (2016) Transmission dynamics of Ebola virus disease and intervention effectiveness in Sierra Leone. Proc Natl Acad Sci 112:4488–4493CrossRef
43.
44.
45.
Feldmann H, Geisbert T (2011) Ebola haemorrhagic fever. Lancet 377:849–862CrossRef
46.
47.
Glynn F, Bower H, Johnson S, Turay C, Sesay D, Mansaray S et al (2018) Variability in intrahousehold transmission of Ebola virus, and estimation of the household secondary attack rate. J Infect Dis 217:232–237CrossRef
48.
Goldstein T, Anthony S, Gbakima A, Bird B, Bangura J, Tremeau-Bravard A, Mazet J (2018) The discovery of Bombali virus adds further support for bats as hosts of ebolaviruses. Nat Microbiol 3:1084–1089CrossRef
49.
50.
51.
Hewlett B, Amola R (2003) Cultural context of Ebola in northern Ugands. Emerg Infect Dis 9(10):1242–1248CrossRef
52.
Hunt L, Gupta-Wright A, Simms V, Tamba F, Knott V, Tamba K et al (2015) Clinical presentation, biochemical, and haematological parameters and their association with outcome in patients with Ebola virus disease: an observational cohort study. Lancet Infect Dis 15(11):1292–1299CrossRef
53.
54.
55.
Information note: Ebola and food safety (2014) Retrieved December 6, 2018, from World Health Organization: information note: Ebola and food safety
56.
57.
58.
59.
Jagadesh S, Sevalie S, Fatoma R, Sesay F, Sahr F, Faragher B, Scott J (2018) Disability among Ebola survivors and their close contacts in Sierra Leone: a retrospective case-controlled cohort study. Clin Infect Dis 66(1):131CrossRef
60.
Janvier F, Foissaud V, Cotte J, Aletti M, Savini H, Cordier P, Sagui E (2016) Monitoring of prognostic laboratory markers in Ebola virus disease. J Infect Dis 213(6):1049CrossRef
61.
Jaxx N, Davis K, Geisbert T, Vogel P, Jaxx G, Topper M, Jahrling P (1996) Lethal experimential infection of rhesus monkeys with Ebola-Zaire (Mayinga) virus by the oral and conjunctival route of exposure. Arch Pathol Lab Med 120(2):140
62.
Jones M, Schun A, Amman B, Sealy TK, Zaki S et al (2015) Experimental inoculation of Egyptian Rousette bats (Rousettus aegyptiacus) with viruses of the ebolavirus and Marburgvirus genera. Viruses:3420–3442
63.
64.
65.
66.
Khan A, Tshioko F, Heymann D, Le Guenno B, Nabeth P, Kerstiens B et al (1999) The reemergence of Ebola hemorrhagic fever Democreatic Republic of the Congo, 1995, Commission de Lutte Contre les Epidemies a Kikwit. J Infect Dis 179(1):S76CrossRef
67.
Kilmarx P, Clarke K, Dietz P, Hamel M, Husain F, McFadden J, Jambai A (2014) Ebola virus disease in health care workers – Sierra Leone, 2014. Morb Mortal Wkly Rep 63(49):1168–1172
68.
Klibanoff E (2014) Some airports have a new security routine: taking your temperature. Retrieved from NPR: goats and soda
69.
Kortepeter M, Bausch D, Bray M (2011) Basic clinical and laboratory features of filoviral hemorrhagic fever. J Infect Dis 204(Suppl 3):S810–S816CrossRef
70.
71.
Kuan M, Lin T, Chuang J, Wu H (2010) Epidemiological trends and the effect of airport fever screening on prevention of domestic dengue fever outbreaks in Taiwan, 1998–2007. Int J Infect Dis 14:e693–e697CrossRef
72.
Leroy E, Kumulungui B, Pourrut X, Roquert P, Hassanin A, Yaba P et al (2005) Fruit bats as reservoirs of Ebola virus. Nature 438:575–576CrossRef
73.
74.
Levy Y, Lane C, Piot P, Beavogui A, Kieh M, Leigh B, Yazdanpanah Y (2018) Prevention of Ebola virus disease through vaccination: where we are in 2018. Lancet 392(10149):787–790CrossRef
75.
Lu H, Qian J, Kargbo D, Zhang X, Yang F, Hu Y et al (2015) Ebola virus outbreak investigation, Sierra Leone, September 28-November 11, 2014. Emerg Infect Dis 21(11):1921CrossRef
76.
Lyon G, Mehta A, Varkey J, Brantly K, Plyler L, McElroy A, Ribner B (2014) Clinical care of two patients with Ebola virus disease in the United States. N Engl J Med 371(25):2402CrossRef
77.
Mananga G, Kapetshi J, Berthest N, Ilunga B, Kabange F et al (2014) Ebola virus disease in the Democratic Republic of Congo. N Engl J Med 371:2083–2091CrossRef
78.
Manguvo A, Mafuvadze B (2015) The impact of traditional and religious practices on the spread of Ebola in West Africa: time for a strategic shift. Pan Afr Med J 22(Suppl 1):9
79.
Mate S, Kugelman J, Nyenswah T, Ladner J, Wiley M, Cordier-Lassalle T, Palacios G (2015) Molecular evidence of sexual transmission of Ebola virus. N Engl J Sci 373(25):2448CrossRef
80.
Mattia J, Vandy M, Chang J, Platt D, Dierberg K, Bausch D, Mishra S (2016) Early clinical sequelae of Ebola virus disease in Sierra Leone: a cross-sectional study. Lancet Infect Dis 16(3):331–338CrossRef
81.
82.
Metzger W, Vivas-Martinez S (2018) Questionable efficacy of the rVSV-ZEBOV Ebola vaccine. Lancet 391(10125):30560–30569CrossRef
83.
Mobula L, MacDermott N, Hoggart C, Brantly K, Plyer W, Brown J et al (2018) Clinical manifestations and modes of death among patients with Ebola virus disease. Am J Trop Med Hyg 94(4):1186–1193CrossRef
84.
Mokgobi M (2014) Understanding traditional African Healting. Afr J Phys Health Educ Recreat Dance 20(Suppl 2):24–34
85.
86.
Muyembe-Tamfum J, Kipasa M, Kiyungu C, Colebunders R (1999) Ebola outbreak in Kikwit, Democratic Republic of the Congo: discovery and control measures. J Infect Dis 179:S259–S262CrossRef
87.
Nkoghe D, Formenty P, Leroy E, Nnegue S, Edou S, Ba J, Mve M (2005) Multiple Ebola virus haemorrhagic fever outbreaks in Gabon, from October 2001 to April 2002. Bull Soc Pathol Exot 98(3):224
88.
89.
Okware S, Omaswa F, Talisuna A, Amandua J, Amone J, Onek P et al (2015) Managing Ebola from rural to urban slum settings: expierences from Uganda. Afr Health Sci 15(1):312–321CrossRef
90.
Olivero J, Fa J, Real R, Marquez A, Farfan M, Vargas M et al (2017) Recent loss of closed forests is associated with Ebola virus disease outbreaks. Sci Rep 7:14291CrossRef
91.
Osemwenkha S (2000) Disease Aetiology in Traditional African Society. Afr: Riv Trimest Stud Documentazione Dell’Istituto Ital l’Afr l’Oriente 55(4):583–590
92.
Palich R, Irenge L, Barte de Sainte Fare E, Augier A, Malw D, Gala J (2017) Ebola virus RNA detection on fomites in close proximity to confirmed Ebola patients; N’Zerekore, Guinea, 2015. PLoS One 12(5):e0177350CrossRef
93.
94.
95.
96.
Reiter P, Turell M, Coleman R, Miller B, Maupin G, Liz J et al (1999) Field investigations of an outbreak of Ebola hemorrhagic fever, Kikwit, Democratic Republic of the Congo, 1995: arthropod studies. J Infect Dis 179(Suppl 1):S148–S154CrossRef
97.
Rowe A, Bertolli J, Khan A, Mukunu R, Muyembe-Tamfum J, Bressler D et al (1999, Feb) Clinical, virologic, and immunologic follow-up of convalescent Ebola hemorrhagic fever patients and their household contacts, Kikwit, Democratic Republic of the Congo. Commission de Lutte contre les Epidémies à Kikwit. J Infect Dis 1:S28–S35CrossRef
98.
99.
Schieffelin J, Shaffer J, Goba A, Gbankie M, Gire S, Colubri A, Garry R (2014) Clinical illness and outcomes in patients with Ebola in Sierra Leone. N Engl J Med 371(22):2092–2100CrossRef
100.
Selvey L, Antão C, Hall R (2015) Evaluation of border entry screening for infectious diseases in humans. CDC: Emerg Infect Dis 21, 197(2)
101.
Shah J (2015) The dead bodies of the West African Ebola epidemic: understanding the importance of traditional burial practices. Inquiries J Soc Sci Art Humanit 7(11):1–4
102.
Shantha J, Crozier I, Yeh S (2017) An update on ocular complications of Ebola virus disease. Curr Opin Opthalmol 28(6):600–606CrossRef
103.
Shears P, O’Dempsey T (2015) Ebola virus disease in Africa: epidemiology oand nosocomial transmission. J Hosp Infect 90(1):1–9CrossRef
104.
Sissoko D, Keita M, Boubacar D, Aliabadi N, Fitter D, Dahl B et al (2017) Ebola virus persistence in breast milk after no reported illness: a likely source of virus transmission from mother to child. Clin Infect Dis 64(4):513–516
105.
Swanepoel R, Leman P, Burt F, Zachariades N, Braack L, Ksiazek T et al (1996) Experimental inoculation of plants and animals with Ebola virus. Emerg Infect Dis 2(4):321–325CrossRef
106.
Thompson E (1965) Primitive African medical Lore and Witchcraft. Bull Med Libr Assoc 53(1):80–94
107.
Tower J, Rolin P, Bausch D, Sanches A, Crary S, Vincent M et al (2004) Rapid diagnosis of Ebola hemorrhagic fever by reverse transcrpition-PCR in an outbreak setting and assessment of patient viral load as a predictor of outcome. J Virol 78(8):4338
108.
Trevisanato S (2007) The ‘Hittite plague’, an epidemic of tularemia and the first record of biological warfare. Med Hypothesis 69(6):1371–1374CrossRef
109.
110.
Uyeki T, Mehta A, Davey R, Liddell A, Wolf T, Vetter P et al (2016) Clinical management of Ebola virus disease in the United States and Europe. N Engl J Med 374(7):636CrossRef
111.
Valeri L, Patterson-Lomba O, Yared G, Ablorh A, Bobb J, Townes W, Harling G (2016) Predicting subnational Ebola virus disease epidemic dynamics from sociodemographic indicators. PLoS One 11:e0163544CrossRef
112.
113.
Victory K, Coronado F, Ifono S, Soropogui T, Dahl B (2015) Ebola transmission linked to a single traditional funeral ceremony – Kissidougou, Guinea, December, 2014–January 2015. MMWR Morb Mortal Wkly Rep 64(14):386–388
114.
115.
116.
Westhoff Smith D, Hill-Batorski L, N’jai A, Eisfeld A, Neumann G, Halfmann P, Kawaoka Y (2016) Ebola virus stability under hospital and environmental conditions. J Infect Dis 214(Suppl 3):S142–S144CrossRef
117.
118.
119.
120.
121.
WHO Ebola Response Team (2014) Ebola virus disease in West Africa – the first 9 months of the epidemic and forward projections. N Engl J Med 371(1):1481–4195CrossRef
122.
WHO: International Commission (1978) Ebola haemorrhagic fever in Zaire, 1976. Bull World Health Organ 56(2):271–293
123.
WHO: International Study Team (1978) Ebola haemorrhagic fever in Sudan, 1976. Bull World Health Organ 56(2):247–270
124.
125.
126.
127.
128.
129.
Zaki S, Shieh W-J, Greer P, Goldsmith C, Ferebee T, Katshitshi J et al (1999) A novel immunohistochemical assay for the detection of Ebola virus in skin: implications for diagnosis, spread, and surveillance of Ebola hemorrhagic fever. J Infect Dis 179:S34–S47CrossRef
Metadaten
Titel
The Emerging Threat of Ebola
verfasst von
Michelle LaBrunda
Naushad Amin
Copyright-Jahr
2020
Verlag
Springer International Publishing
Buch
Global Health Security

Print ISBN: 978-3-030-23490-4

Electronic ISBN: 978-3-030-23491-1

Copyright-Jahr: 2020

DOI
https://doi.org/10.1007/978-3-030-23491-1_6