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2017 | OriginalPaper | Buchkapitel

Toxic Metal Pollution in Pakistan and Its Possible Risks to Public Health

verfasst von : Shakirullah Khan Shakir, Azizullah Azizullah, Waheed Murad, Muhammad K. Daud, Farhat Nabeela, Hazir Rahman, Shafiq ur Rehman, Donat-Peter Häder

Erschienen in: Reviews of Environmental Contamination and Toxicology Volume 242

Verlag: Springer International Publishing

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Abstract

Environmental pollution has increased many folds in recent years and in some places has reached levels that are toxic to living things. Among pollutant types, toxic heavy metals and metalloids are among the chemicals that pose the highest threat to biological systems (Jjemba 2004). Unlike organic pollutants, which are biodegradable, heavy metals are not degraded into less hazardous end products (Gupta et al. 2001). Low concentrations of some heavy metals are essential for life, but some of them like Hg, As, Pb and Cd are biologically non-essential and very toxic to living organisms. Even the essential metals may become toxic if they are present at a concentration above the permissible level (Puttaiah and Kiran 2008). For example, exposure to Zn and Fe oxides produce gastric disorder and vomiting, irritation of the skin and mucous membranes. Intake of Ni, Cr, Pb, Cd and Cu causes heart problems, leukemia and cancer, while Co and Mg can cause anemia and hypertension (Drasch et al. 2006). Similarly, various studies indicated that overexposure to heavy metals in air can cause cardiovascular disorders (Miller et al. 2007; Schwartz 2001), asthma (Wiwatanadate and Liwsrisakun 2011), bronchitis/emphysema (Pope 2000), and other respiratory diseases (Dominici et al. 2006).

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Literatur
Zurück zum Zitat Abbas Z, Chaudary MN, Raza A, Mehmood A (2012) Toxicity of mercury in different samples (water and soils) and its exposure in Pakistan. Sci Int (Lahore) 24:421–429 Abbas Z, Chaudary MN, Raza A, Mehmood A (2012) Toxicity of mercury in different samples (water and soils) and its exposure in Pakistan. Sci Int (Lahore) 24:421–429
Zurück zum Zitat Abbas M, Cheema KJ (2014) Correlation studies of Arsenic level in drinking water and hair samples of females in District Sheikhupura, Pakistan. Int J Curr Microbiol App Sci 3:1077–1085 Abbas M, Cheema KJ (2014) Correlation studies of Arsenic level in drinking water and hair samples of females in District Sheikhupura, Pakistan. Int J Curr Microbiol App Sci 3:1077–1085
Zurück zum Zitat Abbas M, Cheema KJ (2015) Arsenic levels in drinking water and associated health risk in District Sheikhupura, Pakistan. J Animal Plant Sci 25:719–724 Abbas M, Cheema KJ (2015) Arsenic levels in drinking water and associated health risk in District Sheikhupura, Pakistan. J Animal Plant Sci 25:719–724
Zurück zum Zitat Abernathy CO, Thomas DJ, Calderon RL (2003) Health effects and risk assessment of arsenic. J Nutri 133:1536–1538 Abernathy CO, Thomas DJ, Calderon RL (2003) Health effects and risk assessment of arsenic. J Nutri 133:1536–1538
Zurück zum Zitat Abu-Qdais HA (2006) Techno-economic assessment of municipal solid waste management in Jordan. Waste Manage 27:1666–1672 Abu-Qdais HA (2006) Techno-economic assessment of municipal solid waste management in Jordan. Waste Manage 27:1666–1672
Zurück zum Zitat ATSDR (1992) Toxicological profile for cobalt. Agency for Toxic Substances and Disease Registry Public Health Service. U.S. Department of Health and Human Services, Atlanta, GA ATSDR (1992) Toxicological profile for cobalt. Agency for Toxic Substances and Disease Registry Public Health Service. U.S. Department of Health and Human Services, Atlanta, GA
Zurück zum Zitat Affum HA, Oduro-Afriyie K, Nartey VK, Addo MA, Nyarko BJB, Mumuni II, Adu PS, Appiah GK, Coleman A (2011) Lichens as a monitor for atmospheric manganese pollution. Res J Environ Earth Sci 3:534–540 Affum HA, Oduro-Afriyie K, Nartey VK, Addo MA, Nyarko BJB, Mumuni II, Adu PS, Appiah GK, Coleman A (2011) Lichens as a monitor for atmospheric manganese pollution. Res J Environ Earth Sci 3:534–540
Zurück zum Zitat Afridi HI, Kazi TG, Talpur FN, Arain SS, Arain SA, Brahman KD, Panhwar AH, Khan N, Arain MS, Ali J (2015) Assessment of selenium and mercury in biological samples of normal and night blindness children of age groups (3–7) and (8–12) years. Environ Monit Assess 187:82. doi:10.1007/s10661-014-4201-zCrossRef Afridi HI, Kazi TG, Talpur FN, Arain SS, Arain SA, Brahman KD, Panhwar AH, Khan N, Arain MS, Ali J (2015) Assessment of selenium and mercury in biological samples of normal and night blindness children of age groups (3–7) and (8–12) years. Environ Monit Assess 187:82. doi:10.​1007/​s10661-014-4201-zCrossRef
Zurück zum Zitat Afzal M, Shabir G, Iqbal S, Mustafa T, Khan QM, Khalid ZM (2013) Assessment of heavy metal contamination in soil and groundwater at leather industrial area of Kasur, Pakistan. Clean–Soil, Air, Water 41:1–7 Afzal M, Shabir G, Iqbal S, Mustafa T, Khan QM, Khalid ZM (2013) Assessment of heavy metal contamination in soil and groundwater at leather industrial area of Kasur, Pakistan. Clean–Soil, Air, Water 41:1–7
Zurück zum Zitat Agha F, Sadaruddin A, Khatoon N (2005) Effect of environmental lead pollution on blood lead levels in traffic police constables in Islamabad, Pakistan. J Pak Med Assoc 55:10 Agha F, Sadaruddin A, Khatoon N (2005) Effect of environmental lead pollution on blood lead levels in traffic police constables in Islamabad, Pakistan. J Pak Med Assoc 55:10
Zurück zum Zitat Ahmad T, Kahlown MA, Tahir A, Rashid H (2004) Arsenic an emerging issue, experience from Pakistan. In: Proceeding of the 30th WEDC International Conference, Vientiane, Lao PDR p. 459–466 Ahmad T, Kahlown MA, Tahir A, Rashid H (2004) Arsenic an emerging issue, experience from Pakistan. In: Proceeding of the 30th WEDC International Conference, Vientiane, Lao PDR p. 459–466
Zurück zum Zitat Ahmad T, Mumtaz A, Ahmad D, Rashid N (2009) Lead exposure in children living around the automobile and battery repair workshops. Biomedica 25:128–132 Ahmad T, Mumtaz A, Ahmad D, Rashid N (2009) Lead exposure in children living around the automobile and battery repair workshops. Biomedica 25:128–132
Zurück zum Zitat Ahmad SS, Erum S (2010) Integrated assessment of heavy metals pollution along motorway M-2. Soil Environ 29:110–116 Ahmad SS, Erum S (2010) Integrated assessment of heavy metals pollution along motorway M-2. Soil Environ 29:110–116
Zurück zum Zitat Ahmad N, Rahim M, Haris MRHM (2014a) Toxicological impact assessment of heavy metals in human blood and milk samples collected in district Shangla, Pakistan. Sci Int 1:223–226 Ahmad N, Rahim M, Haris MRHM (2014a) Toxicological impact assessment of heavy metals in human blood and milk samples collected in district Shangla, Pakistan. Sci Int 1:223–226
Zurück zum Zitat Ahmad K, Azizullah A, Shama S, Khattak MNK (2014b) Determination of heavy metal contents in water, sediments, and fish tissues of Shizothorax plagiostomus in river Panjkora at Lower Dir, Khyber Pakhtunkhwa, Pakistan. Environ Monit Assess 186:7357–7366 Ahmad K, Azizullah A, Shama S, Khattak MNK (2014b) Determination of heavy metal contents in water, sediments, and fish tissues of Shizothorax plagiostomus in river Panjkora at Lower Dir, Khyber Pakhtunkhwa, Pakistan. Environ Monit Assess 186:7357–7366
Zurück zum Zitat Ahmad A, Ahmad I, Khan MA, Munshi AB, Siddiqui I, Anzar O, Anzar A (2014c) On-set of cataract and accumulation of Copper, Lead and Cadmium in smokers of Karachi, Pakistan. J Environ Toxicol 4:252–258 Ahmad A, Ahmad I, Khan MA, Munshi AB, Siddiqui I, Anzar O, Anzar A (2014c) On-set of cataract and accumulation of Copper, Lead and Cadmium in smokers of Karachi, Pakistan. J Environ Toxicol 4:252–258
Zurück zum Zitat Alam K, Blaschke T, Madl P, Mukhtar A, Hussain M (2011) Aerosol size distribution and mass concentration measurements in various cities of Pakistan. J Environ Monit 13:1944–1952 Alam K, Blaschke T, Madl P, Mukhtar A, Hussain M (2011) Aerosol size distribution and mass concentration measurements in various cities of Pakistan. J Environ Monit 13:1944–1952
Zurück zum Zitat Ali SFA, Mehdi SU, Asif M, Hassan SNU, Mirza EH (2012) Detection of iron and manganese concentrations in human biological fluid with flame atomic absorption spectroscopy (FAAS). International conference on bioscience, biochemistry and pharmaceutical sciences (ICBBPS’2012) Penang, Malaysia Ali SFA, Mehdi SU, Asif M, Hassan SNU, Mirza EH (2012) Detection of iron and manganese concentrations in human biological fluid with flame atomic absorption spectroscopy (FAAS). International conference on bioscience, biochemistry and pharmaceutical sciences (ICBBPS’2012) Penang, Malaysia
Zurück zum Zitat Ali U, Malik RN, Syed JH, Mehmood CT, García LS, Khalid A, Chaudhry MJI (2014) Mass burden and estimated flux of heavy metals in Pakistan coast: sedimentary pollution and eco-toxicological concerns. Environ Sci Pollut Res. doi:10.1007/s11356-014-3612-2CrossRef Ali U, Malik RN, Syed JH, Mehmood CT, García LS, Khalid A, Chaudhry MJI (2014) Mass burden and estimated flux of heavy metals in Pakistan coast: sedimentary pollution and eco-toxicological concerns. Environ Sci Pollut Res. doi:10.​1007/​s11356-014-3612-2CrossRef
Zurück zum Zitat Amin N, Ibrar D, Alam S (2014) Heavy metals accumulation in soil irrigated with industrial effluents of Gadoon Industrial Estate, Pakistan and its comparison with fresh water irrigated soil. J Agric Chem Environ 3:80–87 Amin N, Ibrar D, Alam S (2014) Heavy metals accumulation in soil irrigated with industrial effluents of Gadoon Industrial Estate, Pakistan and its comparison with fresh water irrigated soil. J Agric Chem Environ 3:80–87
Zurück zum Zitat Andrade VM, Mateus ML, Batoréu MC, Aschner M, Marreilha dos Santos AP (2015) Lead, Arsenic, and Manganese metal mixture exposures: focus on biomarkers of effect. Biol Trace Elem Res 166:13–23 Andrade VM, Mateus ML, Batoréu MC, Aschner M, Marreilha dos Santos AP (2015) Lead, Arsenic, and Manganese metal mixture exposures: focus on biomarkers of effect. Biol Trace Elem Res 166:13–23
Zurück zum Zitat Anonymous (2008a) Economic survey of Pakistan. Finance Division, Government of Pakistan, Islamabad Anonymous (2008a) Economic survey of Pakistan. Finance Division, Government of Pakistan, Islamabad
Zurück zum Zitat Anonymous (2008b) Assessment of surface water for drinking quality. Directorate of Land Reclamation Punjab, Irrigation and Power Department, Canal Bank Mughalpura, Lahore, Pakistan Anonymous (2008b) Assessment of surface water for drinking quality. Directorate of Land Reclamation Punjab, Irrigation and Power Department, Canal Bank Mughalpura, Lahore, Pakistan
Zurück zum Zitat Anwar M (2005) Arsenic, cadmium and lead levels in hair and toenail samples in Pakistan. Environ Sci 12:71–86 Anwar M (2005) Arsenic, cadmium and lead levels in hair and toenail samples in Pakistan. Environ Sci 12:71–86
Zurück zum Zitat Arain MB, Kazi TG, Baig JA, Jamali MK, Afridi HI, Shah AQ (2009) Determination of arsenic levels in lake water, sediment, and food stuff from selected area of Sindh, Pakistan: estimation of daily dietary intake. Food Chem Toxicol 47:242–248 Arain MB, Kazi TG, Baig JA, Jamali MK, Afridi HI, Shah AQ (2009) Determination of arsenic levels in lake water, sediment, and food stuff from selected area of Sindh, Pakistan: estimation of daily dietary intake. Food Chem Toxicol 47:242–248
Zurück zum Zitat Ashraf M, Tariq J, Jaffar M (1991) Contents of trace metals in fish, sediment and water from three freshwater reservoirs on the Indus River, Pakistan. Fish Res 12:355–364 Ashraf M, Tariq J, Jaffar M (1991) Contents of trace metals in fish, sediment and water from three freshwater reservoirs on the Indus River, Pakistan. Fish Res 12:355–364
Zurück zum Zitat Awan MA, Ahmed SH, Aslam MR, Qazi IA (2011) Determination of total suspended particulate matter and heavy metals in ambient air of four cities of Pakistan. Iranica J Ener Environ 2:128–132 Awan MA, Ahmed SH, Aslam MR, Qazi IA (2011) Determination of total suspended particulate matter and heavy metals in ambient air of four cities of Pakistan. Iranica J Ener Environ 2:128–132
Zurück zum Zitat Awan MA, Ahmed SH, Aslam MR, Qazi IA, Baig MA (2013) Determination of heavy metals in ambient air particulate matter using laser-induced breakdown spectroscopy. Arab J Sci Eng 38:1655–1661 Awan MA, Ahmed SH, Aslam MR, Qazi IA, Baig MA (2013) Determination of heavy metals in ambient air particulate matter using laser-induced breakdown spectroscopy. Arab J Sci Eng 38:1655–1661
Zurück zum Zitat Ayyub A, Ahmad MS, Ikram N, Shan U (2013) Copper and cadmium levels in hairs and nails; An indicator of heavy metal pollution. Professional Med J 20:296–300 Ayyub A, Ahmad MS, Ikram N, Shan U (2013) Copper and cadmium levels in hairs and nails; An indicator of heavy metal pollution. Professional Med J 20:296–300
Zurück zum Zitat Azeem HA (2010) Analysis of industrial waste water from Kot Lakhpat area (Lahore, Pakistan) by atomic absorption spectrometer. Biologia (Pakistan) 55:35–41 Azeem HA (2010) Analysis of industrial waste water from Kot Lakhpat area (Lahore, Pakistan) by atomic absorption spectrometer. Biologia (Pakistan) 55:35–41
Zurück zum Zitat Aziz R, Rafiq MT, Yang J, Liu D, Lu L, He Z, Daud MK, Li T, Yang X (2014) Impact assessment of cadmium toxicity and Its bioavailability in human cell lines (Caco-2 and HL-7702). Bio Med Res Inter. Article ID 839538, p 8 Aziz R, Rafiq MT, Yang J, Liu D, Lu L, He Z, Daud MK, Li T, Yang X (2014) Impact assessment of cadmium toxicity and Its bioavailability in human cell lines (Caco-2 and HL-7702). Bio Med Res Inter. Article ID 839538, p 8
Zurück zum Zitat Azizullah A, Khattak MNK, Richter P, Häder DP (2011) Water pollution in Pakistan and its impact on public health—a review. Environ Int 37:479–497 Azizullah A, Khattak MNK, Richter P, Häder DP (2011) Water pollution in Pakistan and its impact on public health—a review. Environ Int 37:479–497
Zurück zum Zitat Bacha AA, Durrani MI, Paracha PI (2010) Chemical characteristics of drinking water of Peshawar. Pakistan J Nutr 9:1017–1027 Bacha AA, Durrani MI, Paracha PI (2010) Chemical characteristics of drinking water of Peshawar. Pakistan J Nutr 9:1017–1027
Zurück zum Zitat Barbeau A (1984) Manganese and extrapyramidal disorders (a critical review and tribute to Dr. George C. Cotzias). Neuro Toxicol 5:13–35 Barbeau A (1984) Manganese and extrapyramidal disorders (a critical review and tribute to Dr. George C. Cotzias). Neuro Toxicol 5:13–35
Zurück zum Zitat Barbier O, Jacquillet G, Tauc M, Cougnon M, Poujeol P (2005) Effect of heavy metals on, and handling by, the kidney. Nephron Physiol 99:105–110 Barbier O, Jacquillet G, Tauc M, Cougnon M, Poujeol P (2005) Effect of heavy metals on, and handling by, the kidney. Nephron Physiol 99:105–110
Zurück zum Zitat Baig JA, Kazi TG, Shah AQ, Afridi HI, Kandhro GA, Khan SA (2010) Green analytical procedure for sensitive and selective determination of arsenic in scalp hair samples of arsenic exposed adults of both genders. Pak J Anal Environ Chem 11:23–29 Baig JA, Kazi TG, Shah AQ, Afridi HI, Kandhro GA, Khan SA (2010) Green analytical procedure for sensitive and selective determination of arsenic in scalp hair samples of arsenic exposed adults of both genders. Pak J Anal Environ Chem 11:23–29
Zurück zum Zitat Baig JA, Kazi TG, Shah AQ, Afridi HI, Khan S, Kolachi NF, Kandhro GA, Wadhwa SK, Shah F (2011) Evaluation of toxic risk assessment of arsenic in male subjects through drinking water in southern Sindh Pakistan. Biol Trace Elem Res 143:772–786 Baig JA, Kazi TG, Shah AQ, Afridi HI, Khan S, Kolachi NF, Kandhro GA, Wadhwa SK, Shah F (2011) Evaluation of toxic risk assessment of arsenic in male subjects through drinking water in southern Sindh Pakistan. Biol Trace Elem Res 143:772–786
Zurück zum Zitat Beckman LE, Van Landeghem GF, Sikstrom C, Wahlin A, Markevarn B, Hallmans G (1999) Interaction between haemochromatosis and transferrin receptor genes in different neoplastic disorders. Carcinogenesis 20:1231–1233 Beckman LE, Van Landeghem GF, Sikstrom C, Wahlin A, Markevarn B, Hallmans G (1999) Interaction between haemochromatosis and transferrin receptor genes in different neoplastic disorders. Carcinogenesis 20:1231–1233
Zurück zum Zitat Beede DN, Bloom DE (1995) The economics of municipal solid waste. The World Bank research observer 10:113–150 Beede DN, Bloom DE (1995) The economics of municipal solid waste. The World Bank research observer 10:113–150
Zurück zum Zitat Berg D, Gerlach M, Youdim MB, Double KL, Zecca L, Riederer P, Becker G (2001) Brain iron pathways and their relevance to Parkinson’s disease. J Neurochem 79:225–236 Berg D, Gerlach M, Youdim MB, Double KL, Zecca L, Riederer P, Becker G (2001) Brain iron pathways and their relevance to Parkinson’s disease. J Neurochem 79:225–236
Zurück zum Zitat Bermudez GM, Jasan R, Pla R, Pignata ML (2011) Heavy metal and trace element concentrations in wheat grains: assessment of potential non carcinogenic health hazard through their consumption. J Hazard Mater 193:264–271 Bermudez GM, Jasan R, Pla R, Pignata ML (2011) Heavy metal and trace element concentrations in wheat grains: assessment of potential non carcinogenic health hazard through their consumption. J Hazard Mater 193:264–271
Zurück zum Zitat Brammer H, Ravenscroft P (2009) Arsenic in groundwater: a threat to sustainable agriculture in South and South East Asia: review article. Environ Int 35:647–654 Brammer H, Ravenscroft P (2009) Arsenic in groundwater: a threat to sustainable agriculture in South and South East Asia: review article. Environ Int 35:647–654
Zurück zum Zitat Bruce ED, Abusalih AA, Mcdonald TJ, Autenrieth RL (2007) Comparing deterministic and probabilistic risk assessments for sites contaminated by polycyclic aromatic hydrocarbons (PAHs). J Environ Sci Health 42:697–706 Bruce ED, Abusalih AA, Mcdonald TJ, Autenrieth RL (2007) Comparing deterministic and probabilistic risk assessments for sites contaminated by polycyclic aromatic hydrocarbons (PAHs). J Environ Sci Health 42:697–706
Zurück zum Zitat Butt MS, Sharif K, Bajwa BE, Aziz A (2005) Hazardous effects of sewage water on the environment; focus on heavy metals and chemical composition of soil and vegetables. Manag Environ Quality 16:338–346 Butt MS, Sharif K, Bajwa BE, Aziz A (2005) Hazardous effects of sewage water on the environment; focus on heavy metals and chemical composition of soil and vegetables. Manag Environ Quality 16:338–346
Zurück zum Zitat Caravanos J, Clark E, Fuller R, Lambertson C (2011) Assessing worker and environmental chemical exposure risks at an e-waste recycling and disposal site in Accra, Ghana. J Health Pollut 1:16–25 Caravanos J, Clark E, Fuller R, Lambertson C (2011) Assessing worker and environmental chemical exposure risks at an e-waste recycling and disposal site in Accra, Ghana. J Health Pollut 1:16–25
Zurück zum Zitat Caussy DM (2005) A field guide for detection, management and surveillance of arsenicosis cases. Regional office for South-East Asia. World Health Organization, New Delhi Caussy DM (2005) A field guide for detection, management and surveillance of arsenicosis cases. Regional office for South-East Asia. World Health Organization, New Delhi
Zurück zum Zitat Cefalu WT, Hu FB (2004) Role of chromium in human health and in diabetes. Diab Care 27:2741–2751 Cefalu WT, Hu FB (2004) Role of chromium in human health and in diabetes. Diab Care 27:2741–2751
Zurück zum Zitat Chang SH, Wang K, Chang HF, Ni CW, Wu J, Wong R, Lee HS (2009) Comparison of source identification of metals in road-dust and soil. Soil Sediment Contam 18:669–683 Chang SH, Wang K, Chang HF, Ni CW, Wu J, Wong R, Lee HS (2009) Comparison of source identification of metals in road-dust and soil. Soil Sediment Contam 18:669–683
Zurück zum Zitat Chaoyang W, Cheng W, Linsheng Y (2009) Characterizing spatial distribution and sources of heavy metals in the soils from mining-smelting activities in Shuikoushan, Hunan Province, China. J Environ Sci 21:1230–1236 Chaoyang W, Cheng W, Linsheng Y (2009) Characterizing spatial distribution and sources of heavy metals in the soils from mining-smelting activities in Shuikoushan, Hunan Province, China. J Environ Sci 21:1230–1236
Zurück zum Zitat Chua A, Morgan E (1996) Effects of iron deficiency and iron overload on manganese uptake and deposition in the brain and other organs of the rat. Biol Trace Elem Res 55:39–54 Chua A, Morgan E (1996) Effects of iron deficiency and iron overload on manganese uptake and deposition in the brain and other organs of the rat. Biol Trace Elem Res 55:39–54
Zurück zum Zitat Crossgrove J, Zheng W (2004) Manganese toxicity upon overexposure. NMR Biomed 17:544–553 Crossgrove J, Zheng W (2004) Manganese toxicity upon overexposure. NMR Biomed 17:544–553
Zurück zum Zitat Dawn daily (2013) Arsenic, lead poisoning causing ‘silent epidemics’ in Sindh. Newspaper staff reporter. 20 Feb 2013. Dawn daily (2013) Arsenic, lead poisoning causing ‘silent epidemics’ in Sindh. Newspaper staff reporter. 20 Feb 2013.
Zurück zum Zitat Dominici M, Le Blanc K, Mueller I, Slaper-Cortenbach I, Marini F (2006) Minimal criteria for defining multipotent mesenchymal stromal cells. The inter-national society for cellular therapy position statement. Cytotherapy 8:315–317 Dominici M, Le Blanc K, Mueller I, Slaper-Cortenbach I, Marini F (2006) Minimal criteria for defining multipotent mesenchymal stromal cells. The inter-national society for cellular therapy position statement. Cytotherapy 8:315–317
Zurück zum Zitat Drasch G, Schopfer J, Schrauzer GN (2005) Selenium/cadmium ratios in human prostates: indicators of prostate cancer risk of smokers and nonsmokers, and relevance to the cancer protective effects of selenium. Biol Trace Elem Res 103:103–107 Drasch G, Schopfer J, Schrauzer GN (2005) Selenium/cadmium ratios in human prostates: indicators of prostate cancer risk of smokers and nonsmokers, and relevance to the cancer protective effects of selenium. Biol Trace Elem Res 103:103–107
Zurück zum Zitat Eck P, Wilson L (1989) Toxic metals in human health and disease. Eck Institute of Applied Nutrition and Bioenergetics, Ltd, Phoenix Eck P, Wilson L (1989) Toxic metals in human health and disease. Eck Institute of Applied Nutrition and Bioenergetics, Ltd, Phoenix
Zurück zum Zitat Ellervik C, Mandrup-Poulsen T, Nordestgaard BG, Larsen LE, Appleyard M, Frandsen M (2001) Prevalence of hereditary haemochromatosis in late-onset type 1 diabetes mellitus: a retrospective study. Lancet 358:1405–1409 Ellervik C, Mandrup-Poulsen T, Nordestgaard BG, Larsen LE, Appleyard M, Frandsen M (2001) Prevalence of hereditary haemochromatosis in late-onset type 1 diabetes mellitus: a retrospective study. Lancet 358:1405–1409
Zurück zum Zitat Ensink JHJ, Simmons RW, Hoek WV (2004) Wastewater use in Pakistan: the cases of Haroonabad and Faisalabad. In: Scott CA, Faruqi NI, Raschid-Sally L (eds) Wastewater use in irrigated agriculture: confronting the livelihood and environmental realities. CAB International, Wallingford, pp 91–99 Ensink JHJ, Simmons RW, Hoek WV (2004) Wastewater use in Pakistan: the cases of Haroonabad and Faisalabad. In: Scott CA, Faruqi NI, Raschid-Sally L (eds) Wastewater use in irrigated agriculture: confronting the livelihood and environmental realities. CAB International, Wallingford, pp 91–99
Zurück zum Zitat Faiz Y, Tufail M, Javed MT, Chaudhry MMA, Siddique N (2009) Road dust pollution of Cd, Cu, Ni, Pb and Zn along Islamabad Expressway. Pak Microchem J 92:186–192 Faiz Y, Tufail M, Javed MT, Chaudhry MMA, Siddique N (2009) Road dust pollution of Cd, Cu, Ni, Pb and Zn along Islamabad Expressway. Pak Microchem J 92:186–192
Zurück zum Zitat Farid S (2003) Toxic elements concentration in vegetables irrigated with untreated city effluents. Sci Technol Dev 22:58–60 Farid S (2003) Toxic elements concentration in vegetables irrigated with untreated city effluents. Sci Technol Dev 22:58–60
Zurück zum Zitat Food and Agriculture Organization (FAO) (1985) Water quality for agriculture. Irrigation and drainage paper 29 revised. Food and Agriculture Organization (FAO) (1985) Water quality for agriculture. Irrigation and drainage paper 29 revised.
Zurück zum Zitat Food and Agriculture Organization of the United Nations (FAO) (2002). Investment in Land and Water. In proceedings of the regional consultation Bangkok, Thailand 2002; 3–5 Food and Agriculture Organization of the United Nations (FAO) (2002). Investment in Land and Water. In proceedings of the regional consultation Bangkok, Thailand 2002; 3–5
Zurück zum Zitat Farooqi A, Masuda H, Firdous N (2007) Toxic fluoride and arsenic contaminated groundwater in the Lahore and Kasur districts, Punjab, Pakistan and possible contaminant sources. Environ Pollut 145:839–849 Farooqi A, Masuda H, Firdous N (2007) Toxic fluoride and arsenic contaminated groundwater in the Lahore and Kasur districts, Punjab, Pakistan and possible contaminant sources. Environ Pollut 145:839–849
Zurück zum Zitat Fatoki OS, Awofolu R (2003) Levels of Cd, Hg and Zn in some surface waters from the Eastern Cape Province, South Africa. Water SA 29:375–380 Fatoki OS, Awofolu R (2003) Levels of Cd, Hg and Zn in some surface waters from the Eastern Cape Province, South Africa. Water SA 29:375–380
Zurück zum Zitat Frery N, Nessmann C, Girard F, Lafond J, Moreau T, Blot P (1993) Environmental exposure to cadmium and human birth weight. Toxicology 79:109–118 Frery N, Nessmann C, Girard F, Lafond J, Moreau T, Blot P (1993) Environmental exposure to cadmium and human birth weight. Toxicology 79:109–118
Zurück zum Zitat Gál J, Hursthouse A, Tatner P, Stewart F, Welton R (2008) Cobalt and secondary poisoning in the terrestrial food chain: data review and research gaps to support risk assessment. Environ Int 34:821–838 Gál J, Hursthouse A, Tatner P, Stewart F, Welton R (2008) Cobalt and secondary poisoning in the terrestrial food chain: data review and research gaps to support risk assessment. Environ Int 34:821–838
Zurück zum Zitat Gidlow DA (2004) Lead toxicity. Occup Med 54:76–81 Gidlow DA (2004) Lead toxicity. Occup Med 54:76–81
Zurück zum Zitat Gulfraz M, Mussaddeq Y, Khannum R, Ahmad T (2003) Physicochemical parameters and trace metal concentrations in effluents from various industries in vicinity of Lahore. Sci Technol Dev 22:9–11 Gulfraz M, Mussaddeq Y, Khannum R, Ahmad T (2003) Physicochemical parameters and trace metal concentrations in effluents from various industries in vicinity of Lahore. Sci Technol Dev 22:9–11
Zurück zum Zitat Gupta VK, Gupta M, Sharma S (2003) Process development for the removal of lead and chromium from aqueous solution using red mud and aluminum industry waste. Water Res 35:1125–1134 Gupta VK, Gupta M, Sharma S (2003) Process development for the removal of lead and chromium from aqueous solution using red mud and aluminum industry waste. Water Res 35:1125–1134
Zurück zum Zitat Hamidullah S, Saifullah, Shah MT (2000) Heavy metal pollution in soil of Peshawar city NWFP, Pakistan. Geol Bull Univ Peshawar 33:1–9 Hamidullah S, Saifullah, Shah MT (2000) Heavy metal pollution in soil of Peshawar city NWFP, Pakistan. Geol Bull Univ Peshawar 33:1–9
Zurück zum Zitat Haq I, Hanif W, Hasnain G, Durez S (2012) Socio-economic impacts on human life in arsenic affected area of Basti Rasul Pur, Rahim Yar Khan, Pakistan. Sustain Agric Res 1:100 Haq I, Hanif W, Hasnain G, Durez S (2012) Socio-economic impacts on human life in arsenic affected area of Basti Rasul Pur, Rahim Yar Khan, Pakistan. Sustain Agric Res 1:100
Zurück zum Zitat Huang X (2003) Iron overload and its association with cancer risk in humans: evidence for iron as a carcinogenic metal. Mutat Res 533:153–171 Huang X (2003) Iron overload and its association with cancer risk in humans: evidence for iron as a carcinogenic metal. Mutat Res 533:153–171
Zurück zum Zitat Huang M, Zhou S, Sun B, Zhao Q (2008) Heavy metals in wheat grain: assessment of potential health risk for inhabitants in Kunshan, China. Sci Total Environ 405:54–61 Huang M, Zhou S, Sun B, Zhao Q (2008) Heavy metals in wheat grain: assessment of potential health risk for inhabitants in Kunshan, China. Sci Total Environ 405:54–61
Zurück zum Zitat Hussain S, Masud T, Ahad K (2002) Determination of pesticides residues in selected varieties of mango. Pakistan J Nutr 1:41–42 Hussain S, Masud T, Ahad K (2002) Determination of pesticides residues in selected varieties of mango. Pakistan J Nutr 1:41–42
Zurück zum Zitat Hussain SI, Ghafoor A, Ahmad S, Murtaza G, Sabir M (2006) Irrigation of crops with raw sewage: hazard and assessment in effluent, soil and vegetables. Pak J Agric Sci 43:97–101 Hussain SI, Ghafoor A, Ahmad S, Murtaza G, Sabir M (2006) Irrigation of crops with raw sewage: hazard and assessment in effluent, soil and vegetables. Pak J Agric Sci 43:97–101
Zurück zum Zitat Hussain J, Shah J, Khan LWA, Souza RC, Silva JDSD, Junior EPQ, Nascimento IA (2012) Determination of trace elements in the drinking water of Mardan district KPK, Pakistan. Am Eurasian J Agric Environ Sci 12:1091–1094 Hussain J, Shah J, Khan LWA, Souza RC, Silva JDSD, Junior EPQ, Nascimento IA (2012) Determination of trace elements in the drinking water of Mardan district KPK, Pakistan. Am Eurasian J Agric Environ Sci 12:1091–1094
Zurück zum Zitat Hussain R, Ali L, Hussain I, Khattak SA (2014) Source identification and assessment of physico-chemical parameters and heavy metals in drinking water of Islampur area, Swat, Pakistan. J Himalayan Earth Sci 47:99–106 Hussain R, Ali L, Hussain I, Khattak SA (2014) Source identification and assessment of physico-chemical parameters and heavy metals in drinking water of Islampur area, Swat, Pakistan. J Himalayan Earth Sci 47:99–106
Zurück zum Zitat Ibrahim M, Ahmad N, Anwar SA (1998) International seminar. In: Degraded soils “process, management and analysis.” Univ Agri Faisalabad, Pakistan Ibrahim M, Ahmad N, Anwar SA (1998) International seminar. In: Degraded soils “process, management and analysis.” Univ Agri Faisalabad, Pakistan
Zurück zum Zitat Ilyas A, Sarwar T (2003) Study of trace elements in drinking water in the vicinity of Palosi drain, Peshawar. Pak J Biol Sci 6:86–91 Ilyas A, Sarwar T (2003) Study of trace elements in drinking water in the vicinity of Palosi drain, Peshawar. Pak J Biol Sci 6:86–91
Zurück zum Zitat Ilyas SZ (2007) A review of transport and urban air pollution in Pakistan. J Appl Sci Environ Manage 11:113–121 Ilyas SZ (2007) A review of transport and urban air pollution in Pakistan. J Appl Sci Environ Manage 11:113–121
Zurück zum Zitat International Agency for Research on Cancer (IARC) (2006) Metallic cobalt particles. In: Cobalt in hard-metals and cobalt sulphate, gallium arsenide, indium phosphide and vanadium pentoxide. International Agency for Research on Cancer IARC Monographs on the Evaluation of Carcinogenic Risks to Humans, Lyon, 86 International Agency for Research on Cancer (IARC) (2006) Metallic cobalt particles. In: Cobalt in hard-metals and cobalt sulphate, gallium arsenide, indium phosphide and vanadium pentoxide. International Agency for Research on Cancer IARC Monographs on the Evaluation of Carcinogenic Risks to Humans, Lyon, 86
Zurück zum Zitat Inoue N, Makita Y, Chang LW (1996) Neurological aspects in human exposures to manganese. In: Chang LW (ed) Toxicology of metals. CRC Press, Boca Raton, FL, pp 415–421 Inoue N, Makita Y, Chang LW (1996) Neurological aspects in human exposures to manganese. In: Chang LW (ed) Toxicology of metals. CRC Press, Boca Raton, FL, pp 415–421
Zurück zum Zitat Ishaq M, Jan FA, Khan MA, Ihsanullah I, Ahmad I, Shakirullah M, Roohullah (2013) Effect of mercury and arsenic from industrial effluents on the drinking water and comparison of the water quality of polluted and non-polluted areas: a case study of Peshawar and Lower Dir. Environ Monit Assess 185:1483–1494 Ishaq M, Jan FA, Khan MA, Ihsanullah I, Ahmad I, Shakirullah M, Roohullah (2013) Effect of mercury and arsenic from industrial effluents on the drinking water and comparison of the water quality of polluted and non-polluted areas: a case study of Peshawar and Lower Dir. Environ Monit Assess 185:1483–1494
Zurück zum Zitat Islam-Ul-Haq M, Deedar N, Wajid H (2007) Groundwater arsenic contamination—a multi-directional emerging threat to water scarce areas of Pakistan. 6th International IAHS Groundwater Quality Conference (2–7 December 2007), Fremantle, Western Australia Islam-Ul-Haq M, Deedar N, Wajid H (2007) Groundwater arsenic contamination—a multi-directional emerging threat to water scarce areas of Pakistan. 6th International IAHS Groundwater Quality Conference (2–7 December 2007), Fremantle, Western Australia
Zurück zum Zitat Iqbal MA, Chaudhary MN, Zaib S, Imran M, Ali K, Iqbal A (2011) Accumulation of Heavy Metals (Ni, Cu, Cd, Cr, Pb) in agricultural soils and spring seasonal plants, irrigated by industrial waste water. J Environ Tech Manag 2. Iqbal MA, Chaudhary MN, Zaib S, Imran M, Ali K, Iqbal A (2011) Accumulation of Heavy Metals (Ni, Cu, Cd, Cr, Pb) in agricultural soils and spring seasonal plants, irrigated by industrial waste water. J Environ Tech Manag 2.
Zurück zum Zitat Jan FA, Ishaq M, Khan S, Shakirullah M, Asim SM, Ahmad I (2011) Bioaccumulation of metals in human blood in industrially contaminated area. J Environ Sci 23(12):2069–2077 Jan FA, Ishaq M, Khan S, Shakirullah M, Asim SM, Ahmad I (2011) Bioaccumulation of metals in human blood in industrially contaminated area. J Environ Sci 23(12):2069–2077
Zurück zum Zitat Javed M, Mahmood G (2001) Metal toxicity of water in a stretch of river Ravi from Shahdera to Baloki headworks. Pak J Agric Sci 38:37–42 Javed M, Mahmood G (2001) Metal toxicity of water in a stretch of river Ravi from Shahdera to Baloki headworks. Pak J Agric Sci 38:37–42
Zurück zum Zitat Jjemba PK (2004) Interaction of metals and metalloids with microorganisms in the environment. In: Jjemba PK (ed) Environmental microbiology-principles and applications. Science Publishers, Enfield, pp 257–270 Jjemba PK (2004) Interaction of metals and metalloids with microorganisms in the environment. In: Jjemba PK (ed) Environmental microbiology-principles and applications. Science Publishers, Enfield, pp 257–270
Zurück zum Zitat Johnson MD, Kenney N, Stoica A, Hilakivi-Clarke L, Singh B, Chepko (2003) Cadmium mimics the in vivo effects of estrogen in the uterus and mammary gland. Nat Med 9:1081–1084 Johnson MD, Kenney N, Stoica A, Hilakivi-Clarke L, Singh B, Chepko (2003) Cadmium mimics the in vivo effects of estrogen in the uterus and mammary gland. Nat Med 9:1081–1084
Zurück zum Zitat Kafayatullah Q, Shah MT, Irfan M (2001) Biogeochemical and environmental study of the chromite-rich ultramafic terrain of Malakand area, Pakistan. Environ Geol 40:1482–1486 Kafayatullah Q, Shah MT, Irfan M (2001) Biogeochemical and environmental study of the chromite-rich ultramafic terrain of Malakand area, Pakistan. Environ Geol 40:1482–1486
Zurück zum Zitat Karim Z (2011) Risk assessment of dissolved trace metals in drinking water of Karachi, Pakistan. Bullet Environ Cont Toxicol 86:676–678 Karim Z (2011) Risk assessment of dissolved trace metals in drinking water of Karachi, Pakistan. Bullet Environ Cont Toxicol 86:676–678
Zurück zum Zitat Kashif SR, Akram M, Yaseen M, Ali S (2009) Studies on heavy metals status and their uptake by vegetables in adjoining areas of Hudiara drain in Lahore. Soil Environ 28:7–12 Kashif SR, Akram M, Yaseen M, Ali S (2009) Studies on heavy metals status and their uptake by vegetables in adjoining areas of Hudiara drain in Lahore. Soil Environ 28:7–12
Zurück zum Zitat Kazantzis G (1979) Renal tubular dysfunction and abnormalities of calcium metabolism in cadmium workers. Environ Health Perspect 28:155–159 Kazantzis G (1979) Renal tubular dysfunction and abnormalities of calcium metabolism in cadmium workers. Environ Health Perspect 28:155–159
Zurück zum Zitat Kazi TG, Arain MB, Baig JA, Jamali MK, Afridi HI, Jalbani N, Sarfraza RA, Shaha AQ, Niaza A (2009) The correlation of arsenic levels in drinking water with the biological samples of skin disorders. Sci Total Environ 407:1019–1026 Kazi TG, Arain MB, Baig JA, Jamali MK, Afridi HI, Jalbani N, Sarfraza RA, Shaha AQ, Niaza A (2009) The correlation of arsenic levels in drinking water with the biological samples of skin disorders. Sci Total Environ 407:1019–1026
Zurück zum Zitat Khan MA, Wajid A, Noor S, Khattak FK, Akhtar S, Rehman IU (2008a) Effect of soil contamination on some heavy metals contents of Cannabis sativa. J Chem Soc Pak 30:805 Khan MA, Wajid A, Noor S, Khattak FK, Akhtar S, Rehman IU (2008a) Effect of soil contamination on some heavy metals contents of Cannabis sativa. J Chem Soc Pak 30:805
Zurück zum Zitat Khan DA, Qayyum S, Saleem S, Khan FA (2008b) Lead-induced oxidative stress adversely affects health of the occupational workers. Toxicol Ind Health 24:611–618 Khan DA, Qayyum S, Saleem S, Khan FA (2008b) Lead-induced oxidative stress adversely affects health of the occupational workers. Toxicol Ind Health 24:611–618
Zurück zum Zitat Khan S, Cao Q, Zheng YM, Huang YZ, Zhu YG (2008c) Health risks of heavy metals in contaminated soils and food crops irrigated with wastewater in Beijing China. Environ Pollut 152:686–692 Khan S, Cao Q, Zheng YM, Huang YZ, Zhu YG (2008c) Health risks of heavy metals in contaminated soils and food crops irrigated with wastewater in Beijing China. Environ Pollut 152:686–692
Zurück zum Zitat Khan DA, Qayyum S, Saleem S, Ansari WM, Khan FA (2010) Lead exposure and its adverse health effects among occupational worker’s children. Toxicol Indus Health 26:497–504 Khan DA, Qayyum S, Saleem S, Ansari WM, Khan FA (2010) Lead exposure and its adverse health effects among occupational worker’s children. Toxicol Indus Health 26:497–504
Zurück zum Zitat Khan T, Muhammad S, Khan B, Khan H (2011a) Investigating the levels of selected heavy metals in surface water of Shah Alam River (A tributary of River Kabul, Khyber Pakhtunkhwa). J Himalayan Earth Sci 44:71–79 Khan T, Muhammad S, Khan B, Khan H (2011a) Investigating the levels of selected heavy metals in surface water of Shah Alam River (A tributary of River Kabul, Khyber Pakhtunkhwa). J Himalayan Earth Sci 44:71–79
Zurück zum Zitat Khan MN, Wasim AA, Sarwar A, Rasheed ZF (2011b) Assessment of heavy metal toxicants in the roadside soil along the N-5, National Highway, Pakistan. Environ Monit Assess 182:587–595 Khan MN, Wasim AA, Sarwar A, Rasheed ZF (2011b) Assessment of heavy metal toxicants in the roadside soil along the N-5, National Highway, Pakistan. Environ Monit Assess 182:587–595
Zurück zum Zitat Khan S, Shahnaz M, Jehan N, Rehman S, Shah MT, Din I (2012a) Drinking water quality and human health risk in Charsadda district, Pakistan. J Clean Prod 10:10–16 Khan S, Shahnaz M, Jehan N, Rehman S, Shah MT, Din I (2012a) Drinking water quality and human health risk in Charsadda district, Pakistan. J Clean Prod 10:10–16
Zurück zum Zitat Khan S, Shah MT, Din IU, Rehman S (2012b) Mercury exposure of workers and health problems related with small-scale gold panning and extraction. J Chem Soc Pak 34:870–876 Khan S, Shah MT, Din IU, Rehman S (2012b) Mercury exposure of workers and health problems related with small-scale gold panning and extraction. J Chem Soc Pak 34:870–876
Zurück zum Zitat Khan DA, Mushtaq S, Khan FA, Khan MQA (2013a) Toxic effects of chromium on tannery workers at Sialkot (Pakistan). Toxicol Indus Health 29:209–215 Khan DA, Mushtaq S, Khan FA, Khan MQA (2013a) Toxic effects of chromium on tannery workers at Sialkot (Pakistan). Toxicol Indus Health 29:209–215
Zurück zum Zitat Khan K, Lu Y, Khan H, Zakir S, Khan IS, Khan AA, Wei L, Wang T (2013b) Health risks associated with heavy metals in the drinking water of Swat, northern Pakistan. J Environ Sci (China) 25:1–10 Khan K, Lu Y, Khan H, Zakir S, Khan IS, Khan AA, Wei L, Wang T (2013b) Health risks associated with heavy metals in the drinking water of Swat, northern Pakistan. J Environ Sci (China) 25:1–10
Zurück zum Zitat Khan SA, Ali A, Baig MN (2013c) The linkage between agricultural practices and environmental degradation. J Environ Treat Tech 1:19–22 Khan SA, Ali A, Baig MN (2013c) The linkage between agricultural practices and environmental degradation. J Environ Treat Tech 1:19–22
Zurück zum Zitat Khan K, Khan H, Lu Y, Ihsanullah I, Nawab J, Khan S, Shah NS, Shamshad I, Maryam A (2014) Evaluation of toxicological risk of foodstuffs contaminated with heavy metals in Swat, Pakistan. Ecotoxicol Environ Safety 108:224–232 Khan K, Khan H, Lu Y, Ihsanullah I, Nawab J, Khan S, Shah NS, Shamshad I, Maryam A (2014) Evaluation of toxicological risk of foodstuffs contaminated with heavy metals in Swat, Pakistan. Ecotoxicol Environ Safety 108:224–232
Zurück zum Zitat Khan ZI, Ahmad K, Ashraf M, Parveen R, Mustafa I, Khan A et al (2015) Bioaccumulation of heavy metals and metalloids in luffa (Luffa cylindrica L.) irrigated with domestic wastewater in Jhang, Pakistan: a prospect for human nutrition. Pak J Bot 47(1):217–224 Khan ZI, Ahmad K, Ashraf M, Parveen R, Mustafa I, Khan A et al (2015) Bioaccumulation of heavy metals and metalloids in luffa (Luffa cylindrica L.) irrigated with domestic wastewater in Jhang, Pakistan: a prospect for human nutrition. Pak J Bot 47(1):217–224
Zurück zum Zitat Khattak MI, Khattak MI, Mohibullah M (2012) Study of heavy metal pollution in mangrove sediments reference to marine environment along the coastal areas of Pakistan. Pak J Bot 44:373–378 Khattak MI, Khattak MI, Mohibullah M (2012) Study of heavy metal pollution in mangrove sediments reference to marine environment along the coastal areas of Pakistan. Pak J Bot 44:373–378
Zurück zum Zitat Latif MI, Lone MI, Khan KS (2008) Heavy metals contamination of different water sources, soils and vegetables in Rawalpindi area. Soil Environ 27:29–35 Latif MI, Lone MI, Khan KS (2008) Heavy metals contamination of different water sources, soils and vegetables in Rawalpindi area. Soil Environ 27:29–35
Zurück zum Zitat Lee JS, Chon HT, Kim KW (2005) Human risk assessment of As, Cd, Cu and Zn in the abandoned metal mine site. Environ Geochem Health 27:185–191 Lee JS, Chon HT, Kim KW (2005) Human risk assessment of As, Cd, Cu and Zn in the abandoned metal mine site. Environ Geochem Health 27:185–191
Zurück zum Zitat Lehloesa LJ, Muyima NYO (2000) Evaluation of the impact of household treatment procedures on the quality of groundwater supplies in the rural community of Victoria district, Eastern Cape: technical note. Water SA 26:285–290 Lehloesa LJ, Muyima NYO (2000) Evaluation of the impact of household treatment procedures on the quality of groundwater supplies in the rural community of Victoria district, Eastern Cape: technical note. Water SA 26:285–290
Zurück zum Zitat Li PH, Kong SF, Geng CM, Han B, Lu B, Sun RF, Zhao RJ, Bai ZP (2013a) Assessing the hazardous risks of vehicle inspection workers’ exposure to particulate heavy metals in their work places. Aerosol Air Qual Res 13:255–265 Li PH, Kong SF, Geng CM, Han B, Lu B, Sun RF, Zhao RJ, Bai ZP (2013a) Assessing the hazardous risks of vehicle inspection workers’ exposure to particulate heavy metals in their work places. Aerosol Air Qual Res 13:255–265
Zurück zum Zitat Li X, Poon CS, Liu PS (2001) Heavy metal contamination of urban soils and street dusts in Hong Kong. Appl Geochem 16:1361–1368 Li X, Poon CS, Liu PS (2001) Heavy metal contamination of urban soils and street dusts in Hong Kong. Appl Geochem 16:1361–1368
Zurück zum Zitat Li DP, Wu ZJ (2008) Impact of chemical fertilizers application on soil ecological environment. J Appl Ecol 19:1158–1165 Li DP, Wu ZJ (2008) Impact of chemical fertilizers application on soil ecological environment. J Appl Ecol 19:1158–1165
Zurück zum Zitat Li P, Wu HJ, Chen B (2013b) A resource-oriented solid waste management system for a mixed rural-urban area through Monte Carlo simulation-based fuzzy programming. Math Probl Eng. doi:10.1155/2013/780354CrossRef Li P, Wu HJ, Chen B (2013b) A resource-oriented solid waste management system for a mixed rural-urban area through Monte Carlo simulation-based fuzzy programming. Math Probl Eng. doi:10.​1155/​2013/​780354CrossRef
Zurück zum Zitat Liu X, Song Q, Tang Y, Li W, Xu J, Wu J, Wang F, Brookes PC (2013) Human health risk assessment of heavy metals in soil-vegetable system: A multi-medium analysis. Sci Total Environ, 530–540 Liu X, Song Q, Tang Y, Li W, Xu J, Wu J, Wang F, Brookes PC (2013) Human health risk assessment of heavy metals in soil-vegetable system: A multi-medium analysis. Sci Total Environ, 530–540
Zurück zum Zitat Lone MI, Saleem S, Mahmood T, Saifullah K, Hussain G (2003) Heavy metal contents of vegetables irrigated by sewage/tube-well water. Int J Agri Biol 5:533–535 Lone MI, Saleem S, Mahmood T, Saifullah K, Hussain G (2003) Heavy metal contents of vegetables irrigated by sewage/tube-well water. Int J Agri Biol 5:533–535
Zurück zum Zitat Mahar A, Malik RN, Qadir A, Ahmed T, Khan Z, Khan MA (2007) Review and Analysis of Current Solid Waste Management Situation in Urban Areas of Pakistan. Proceedings of the International Conference on Sustainable Solid Waste Management, 5–7 September Chennai, India, pp 34–41 Mahar A, Malik RN, Qadir A, Ahmed T, Khan Z, Khan MA (2007) Review and Analysis of Current Solid Waste Management Situation in Urban Areas of Pakistan. Proceedings of the International Conference on Sustainable Solid Waste Management, 5–7 September Chennai, India, pp 34–41
Zurück zum Zitat Mahmood S, Maqbool A (2006) Impacts of wastewater irrigation on water quality and on the health of local community in Faisalabad. Pak J Water Res 10:19–22 Mahmood S, Maqbool A (2006) Impacts of wastewater irrigation on water quality and on the health of local community in Faisalabad. Pak J Water Res 10:19–22
Zurück zum Zitat Mahmood A, Malik RN (2014) Human health risk assessment of heavy metals via consumption of contaminated vegetables collected from different irrigation sources in Lahore, Pakistan. Arab J Chem 7:91–99 Mahmood A, Malik RN (2014) Human health risk assessment of heavy metals via consumption of contaminated vegetables collected from different irrigation sources in Lahore, Pakistan. Arab J Chem 7:91–99
Zurück zum Zitat Majid H, Alam K, Madl P (2011) Aerosol size distribution, mass concentration measurement and lung deposition calculations for metropolitan cities of Pakistan. Research thesis, University of Salzburg, Austria Majid H, Alam K, Madl P (2011) Aerosol size distribution, mass concentration measurement and lung deposition calculations for metropolitan cities of Pakistan. Research thesis, University of Salzburg, Austria
Zurück zum Zitat Majidano SA, Khuhawar MY (2009) Distribution of heavy metals in the ground water of Taluka Daur, District Nawabshah, Sindh, Pakistan, and its impacts on human health. J Chem Soc Pak 31:408–414 Majidano SA, Khuhawar MY (2009) Distribution of heavy metals in the ground water of Taluka Daur, District Nawabshah, Sindh, Pakistan, and its impacts on human health. J Chem Soc Pak 31:408–414
Zurück zum Zitat Malana MA, Khosa MA (2011) Groundwater pollution with special focus on arsenic, Dera Ghazi Khan-Pakistan. J Saudi Chem Soc 15:39–47 Malana MA, Khosa MA (2011) Groundwater pollution with special focus on arsenic, Dera Ghazi Khan-Pakistan. J Saudi Chem Soc 15:39–47
Zurück zum Zitat Malik RN, Husain SZ, Nazir I (2010) Heavy metal contamination and accumulation in soil and wild plant species from industrial area of Islamabad, Pakistan. Pak J Bot 42:291–301 Malik RN, Husain SZ, Nazir I (2010) Heavy metal contamination and accumulation in soil and wild plant species from industrial area of Islamabad, Pakistan. Pak J Bot 42:291–301
Zurück zum Zitat Manzoor S, Shah MH, Shaheen N, Khalique A, Jaffar M (2006) Multivariate analysis of trace metals in textile effluents in relation to soil and groundwater. J Haz Mat 137:31–37 Manzoor S, Shah MH, Shaheen N, Khalique A, Jaffar M (2006) Multivariate analysis of trace metals in textile effluents in relation to soil and groundwater. J Haz Mat 137:31–37
Zurück zum Zitat Mastoi GM, Shah SGS, Khuhawar MY (2008) Assessment of water quality of Manchar Lake in Sindh (Pakistan). Environ Monit Assess 141:287–296 Mastoi GM, Shah SGS, Khuhawar MY (2008) Assessment of water quality of Manchar Lake in Sindh (Pakistan). Environ Monit Assess 141:287–296
Zurück zum Zitat Mumtaz M, Siddique A, Mukhtar N, Mehboob T (1999) Status of trace elements level in blood samples of different age population of Karachi (Pakistan). Tr J Med Sci 29:697–699 Mumtaz M, Siddique A, Mukhtar N, Mehboob T (1999) Status of trace elements level in blood samples of different age population of Karachi (Pakistan). Tr J Med Sci 29:697–699
Zurück zum Zitat Mehmood S, Ahmad A, Ahmed A, Khalid N, Javed T (2013) Drinking water quality in capital city of Pakistan. Sci Report 2:637 Mehmood S, Ahmad A, Ahmed A, Khalid N, Javed T (2013) Drinking water quality in capital city of Pakistan. Sci Report 2:637
Zurück zum Zitat McGregor DB, Baan RA, Partensky C, Rice JM, Wilbourn JD (2000) Evaluation of the carcinogenic risks to humans associated with surgical implants and other foreign bodies—a report of an IARC Monographs Programme Meeting. Eur J Cancer 36:307–313 McGregor DB, Baan RA, Partensky C, Rice JM, Wilbourn JD (2000) Evaluation of the carcinogenic risks to humans associated with surgical implants and other foreign bodies—a report of an IARC Monographs Programme Meeting. Eur J Cancer 36:307–313
Zurück zum Zitat Midrar-Ul-Haq, Khattak RA, Puno HK, Saif MS, Memon KS (2005) Surface and ground water contamination in NWFP and Sindh provinces with respect to trace elements. Int J Agric Biol 7:214–217 Midrar-Ul-Haq, Khattak RA, Puno HK, Saif MS, Memon KS (2005) Surface and ground water contamination in NWFP and Sindh provinces with respect to trace elements. Int J Agric Biol 7:214–217
Zurück zum Zitat Miller KA, Siscovick DS, Sheppard L, Shepherd K, Sullivan JH (2007) Long term exposure to air pollution and incidence of cardiovascular events in women. N Engl J Med 356:447–458 Miller KA, Siscovick DS, Sheppard L, Shepherd K, Sullivan JH (2007) Long term exposure to air pollution and incidence of cardiovascular events in women. N Engl J Med 356:447–458
Zurück zum Zitat Milman N, Pedersen P, Steig T, Byg KE, Graudal N, Fenger K (2001) Clinically overt hereditary hemochromatosis in Denmark 1948–1985: epidemiology, factors of significance for long-term survival, and causes of death in 179 patients. Ann Hematol 80:737–744 Milman N, Pedersen P, Steig T, Byg KE, Graudal N, Fenger K (2001) Clinically overt hereditary hemochromatosis in Denmark 1948–1985: epidemiology, factors of significance for long-term survival, and causes of death in 179 patients. Ann Hematol 80:737–744
Zurück zum Zitat Muhammad S, Shah MT, Khan S (2011) Health risk assessment of heavy metals and their source apportionment in drinking water of Kohistan region, northern Pakistan. Microchem J 98:334–343 Muhammad S, Shah MT, Khan S (2011) Health risk assessment of heavy metals and their source apportionment in drinking water of Kohistan region, northern Pakistan. Microchem J 98:334–343
Zurück zum Zitat Murtaza G, Ghafoor A, Qadir M, Rashid MK (2003) Accumulation and bioavailability of Cd, Co and Mn in soils and vegetables irrigated with city effluents. Pak J Agric Sci 40:18–24 Murtaza G, Ghafoor A, Qadir M, Rashid MK (2003) Accumulation and bioavailability of Cd, Co and Mn in soils and vegetables irrigated with city effluents. Pak J Agric Sci 40:18–24
Zurück zum Zitat Murtaza G, Ghafoor A, Qadir MJ (2008) Accumulation and implications of cadmium, cobalt and manganese in soils and vegetables irrigated with city effluent. J Sci Food Agric 88:100–107 Murtaza G, Ghafoor A, Qadir MJ (2008) Accumulation and implications of cadmium, cobalt and manganese in soils and vegetables irrigated with city effluent. J Sci Food Agric 88:100–107
Zurück zum Zitat Mushtaq N, Khan KS (2010) Heavy metals contamination of soils in response to wastewater irrigation in Rawalpindi region. Pak J Agri Sci 47:215–224 Mushtaq N, Khan KS (2010) Heavy metals contamination of soils in response to wastewater irrigation in Rawalpindi region. Pak J Agri Sci 47:215–224
Zurück zum Zitat Nafees M, Khan H, Jan MR, Rashid N, Khan F (2009) Soil contamination in Swat Valley caused by Cadmium and Copper. Sarhad J Agric 25:37–43 Nafees M, Khan H, Jan MR, Rashid N, Khan F (2009) Soil contamination in Swat Valley caused by Cadmium and Copper. Sarhad J Agric 25:37–43
Zurück zum Zitat Nagajyoti PC, Lee KD, Sreekanth TVM (2010) Heavy metals, occurrence and toxicity for plants: a review. Environ Chem Lett 8:199–216 Nagajyoti PC, Lee KD, Sreekanth TVM (2010) Heavy metals, occurrence and toxicity for plants: a review. Environ Chem Lett 8:199–216
Zurück zum Zitat Naseem S, Hamza S, Bashir E, Pirzada T, Talpur MMA (2013) Trace element geochemistry of groundwater of winder Balochistan Pakistan and its appraisal for irrigation water quality. Brit J Appl Sci Tech 3:182–198 Naseem S, Hamza S, Bashir E, Pirzada T, Talpur MMA (2013) Trace element geochemistry of groundwater of winder Balochistan Pakistan and its appraisal for irrigation water quality. Brit J Appl Sci Tech 3:182–198
Zurück zum Zitat Nasrullah, Naz R, Bibi H, Iqbal M, Durrani MI (2006) Pollution load in industrial effluent and ground water of Gadoon Amazai Induatrial Estate (GAIE) Swabi, NWFP. J Agric Biol Sci 1:18–24 Nasrullah, Naz R, Bibi H, Iqbal M, Durrani MI (2006) Pollution load in industrial effluent and ground water of Gadoon Amazai Induatrial Estate (GAIE) Swabi, NWFP. J Agric Biol Sci 1:18–24
Zurück zum Zitat Nazif W, Perveen S, Shah SA (2006) Evaluation of irrigation water for heavy metals of Akbarpura area. J Agric Biol Sci 1:51–54 Nazif W, Perveen S, Shah SA (2006) Evaluation of irrigation water for heavy metals of Akbarpura area. J Agric Biol Sci 1:51–54
Zurück zum Zitat Nickson RT, McArthur JM, Shrestha B, Kyaw-Myint TO, Lowry D (2005) Arsenic and other drinking water quality issues, Muzaffargarh District, Pakistan. Appl Geochem 20:55–68 Nickson RT, McArthur JM, Shrestha B, Kyaw-Myint TO, Lowry D (2005) Arsenic and other drinking water quality issues, Muzaffargarh District, Pakistan. Appl Geochem 20:55–68
Zurück zum Zitat Nordberg GF (2004) Cadmium and health in the 21st century—historical remarks and trends for the future. Biometals 17:485–489 Nordberg GF (2004) Cadmium and health in the 21st century—historical remarks and trends for the future. Biometals 17:485–489
Zurück zum Zitat NSDWQ-Pak (2008) National Standards for Drinking Water Quality, Health Services Academy, Ministry of Health, Government of Pakistan NSDWQ-Pak (2008) National Standards for Drinking Water Quality, Health Services Academy, Ministry of Health, Government of Pakistan
Zurück zum Zitat Oller AR, Costa M, Oberdörster G (1997) Carcinogenicity assessment of selected nickel compounds. Toxicol Appl Pharmacol 143:152–166 Oller AR, Costa M, Oberdörster G (1997) Carcinogenicity assessment of selected nickel compounds. Toxicol Appl Pharmacol 143:152–166
Zurück zum Zitat Pak-SCEA (2006) Pakistan; Strategic Country Environmental Assessment Report: rising to the challenges Pak-SCEA (2006) Pakistan; Strategic Country Environmental Assessment Report: rising to the challenges
Zurück zum Zitat Panhwar AH, Kazi TG, Afridi HI, Arain SA, Arain MS, Brahaman KD, Naeemullah, Arain SS (2016) Correlation of cadmium and aluminum in blood samples of kidney disorder patients with drinking water and tobacco smoking: related health risk. Environ Geochem Health 38:1–10. doi:10.1007/s10653-015-9715-yCrossRef Panhwar AH, Kazi TG, Afridi HI, Arain SA, Arain MS, Brahaman KD, Naeemullah, Arain SS (2016) Correlation of cadmium and aluminum in blood samples of kidney disorder patients with drinking water and tobacco smoking: related health risk. Environ Geochem Health 38:1–10. doi:10.​1007/​s10653-015-9715-yCrossRef
Zurück zum Zitat Parkkila S, Niemelä O, Savolainen ER, Koistinen P (2001) HFE mutations do not account for transfusional iron overload in patients with acute myeloid leukemia. Transfusion 41:828–831 Parkkila S, Niemelä O, Savolainen ER, Koistinen P (2001) HFE mutations do not account for transfusional iron overload in patients with acute myeloid leukemia. Transfusion 41:828–831
Zurück zum Zitat Paustenbach DJ (2002) Human and ecological risk assessment: theory and practice. Wiley, New York Paustenbach DJ (2002) Human and ecological risk assessment: theory and practice. Wiley, New York
Zurück zum Zitat Parveen N, Ghaffar A, Shirazi SA, Bhalli MN (2012) Spatial distribution of heavy metal contamination in road side soils of Faisalabad Pakistan. Pak J Sci 64:309 Parveen N, Ghaffar A, Shirazi SA, Bhalli MN (2012) Spatial distribution of heavy metal contamination in road side soils of Faisalabad Pakistan. Pak J Sci 64:309
Zurück zum Zitat Piasek M, Laskey JW (1999) Effects of in vitro cadmium exposure on ovarian steroidogenesis in rats. J Appl Toxicol 19:211–217 Piasek M, Laskey JW (1999) Effects of in vitro cadmium exposure on ovarian steroidogenesis in rats. J Appl Toxicol 19:211–217
Zurück zum Zitat Pope CA (2000) Epidemiology of fine particulate air pollution and human health: biologic mechanisms and who is at risk? Environ Health Perspect 108:713–723 Pope CA (2000) Epidemiology of fine particulate air pollution and human health: biologic mechanisms and who is at risk? Environ Health Perspect 108:713–723
Zurück zum Zitat Porea TJ, Belmont JW, Mahoney DH (2000) Zinc-induced anemia and neutropenia in an adolescent. J Pediatr 136:688–690 Porea TJ, Belmont JW, Mahoney DH (2000) Zinc-induced anemia and neutropenia in an adolescent. J Pediatr 136:688–690
Zurück zum Zitat Puttaiah ET, Kiran BR (2008) Heavy metal transport in a sewage fed Lake of Karnataka, India. Proceedings of Taal. 2007. The 12th World Lake Conference; Jaipur, India 2008. pp 347:347–354 Puttaiah ET, Kiran BR (2008) Heavy metal transport in a sewage fed Lake of Karnataka, India. Proceedings of Taal. 2007. The 12th World Lake Conference; Jaipur, India 2008. pp 347:347–354
Zurück zum Zitat Qadir NF (2002) Air quality in urban areas in Pakistan vs transport planning: issues and management tools. Document 16B, presentation Qadir NF (2002) Air quality in urban areas in Pakistan vs transport planning: issues and management tools. Document 16B, presentation
Zurück zum Zitat Rahman A, Lee HK, Khan MA (1997) Domestic water contamination in rapidly growing mega cities of Asia: case of Karachi, Pakistan. Environ Monit Assess 44:339–360 Rahman A, Lee HK, Khan MA (1997) Domestic water contamination in rapidly growing mega cities of Asia: case of Karachi, Pakistan. Environ Monit Assess 44:339–360
Zurück zum Zitat Rahman S, Khalid N, Zaidi ZH, Ahmad S, Iqbal MZ (2006) Non-occupational lead exposure and hypertension in Pakistani adults. J Zhejiang Univ Sci B 7:732–737 Rahman S, Khalid N, Zaidi ZH, Ahmad S, Iqbal MZ (2006) Non-occupational lead exposure and hypertension in Pakistani adults. J Zhejiang Univ Sci B 7:732–737
Zurück zum Zitat Rasmussen ML, Folsom AR, Catellier DJ, Tsai MY, Garg U, Eckfeldt JH (2001) A prospective study of coronary heart disease and the hemochromatosis gene (HFE) C282Y mutation: the atherosclerosis risk in communities (ARIC) study. Atherosclerosis 154:739–746 Rasmussen ML, Folsom AR, Catellier DJ, Tsai MY, Garg U, Eckfeldt JH (2001) A prospective study of coronary heart disease and the hemochromatosis gene (HFE) C282Y mutation: the atherosclerosis risk in communities (ARIC) study. Atherosclerosis 154:739–746
Zurück zum Zitat Raza N, Niazi SB, Sajid M, Iqbal F, Ali M (2007) Studies on relationship between season and inorganic elements of Kallar Kahar Lake (Chakwal), Pakistan. J Res (Sci) 18:61–68 Raza N, Niazi SB, Sajid M, Iqbal F, Ali M (2007) Studies on relationship between season and inorganic elements of Kallar Kahar Lake (Chakwal), Pakistan. J Res (Sci) 18:61–68
Zurück zum Zitat Rehman W, Zeb A, Noor N, Nawaz M (2008) Heavy metal pollution assessment in various industries of Pakistan. Environ Geol 55:353–358 Rehman W, Zeb A, Noor N, Nawaz M (2008) Heavy metal pollution assessment in various industries of Pakistan. Environ Geol 55:353–358
Zurück zum Zitat Riess ML, Halm JK (2007) Lead poisoning in an adult: lead mobilization by pregnancy. J Gen Intern Med 22:1212–1215 Riess ML, Halm JK (2007) Lead poisoning in an adult: lead mobilization by pregnancy. J Gen Intern Med 22:1212–1215
Zurück zum Zitat Rohrs LC (1957) Metal-fume fever from inhaling zinc oxide. AMA Arch Ind Health 16:42–47 Rohrs LC (1957) Metal-fume fever from inhaling zinc oxide. AMA Arch Ind Health 16:42–47
Zurück zum Zitat Saif MS, Midrar-Ul-Haq, Memon KS (2005) Heavy metals contamination through industrial effluent to irrigation water and soil in Korangi area of Karachi (Pakistan). Int J Agri Biol 7:646–648 Saif MS, Midrar-Ul-Haq, Memon KS (2005) Heavy metals contamination through industrial effluent to irrigation water and soil in Korangi area of Karachi (Pakistan). Int J Agri Biol 7:646–648
Zurück zum Zitat Saleemi MA (1993) Environmental assessment and management of irrigation and drainage scheme for sustainable agriculture growth. EPA, Lahore, p 64 Saleemi MA (1993) Environmental assessment and management of irrigation and drainage scheme for sustainable agriculture growth. EPA, Lahore, p 64
Zurück zum Zitat Sayre LM, Perry G, Atwood CS, Smith MA (2000) The role of metals in neurodegenerative diseases. Cell Mol Biol (Noisy-le-Grand) 46:731–741 Sayre LM, Perry G, Atwood CS, Smith MA (2000) The role of metals in neurodegenerative diseases. Cell Mol Biol (Noisy-le-Grand) 46:731–741
Zurück zum Zitat Schneidemesser EV, Stone EA, Quraishi TA, Shafer MM, Schauer JJ (2010) Toxic metals in the atmosphere in Lahore, Pakistan. Sci Total Environ 408:1640–1648 Schneidemesser EV, Stone EA, Quraishi TA, Shafer MM, Schauer JJ (2010) Toxic metals in the atmosphere in Lahore, Pakistan. Sci Total Environ 408:1640–1648
Zurück zum Zitat Schwartz J (2001) Air pollution and blood markers of cardiovascular risk. Environ Health Perspect 109:405–409 Schwartz J (2001) Air pollution and blood markers of cardiovascular risk. Environ Health Perspect 109:405–409
Zurück zum Zitat Scragg A (2006) Environmental biotechnology, 2nd edn. Oxford University Press, Oxford, UK Scragg A (2006) Environmental biotechnology, 2nd edn. Oxford University Press, Oxford, UK
Zurück zum Zitat SEPA (1995) Environmental quality standard for soils. State Environmental Protection Administration, China. GB15618-1995 SEPA (1995) Environmental quality standard for soils. State Environmental Protection Administration, China. GB15618-1995
Zurück zum Zitat Shah AQ, Kazi TG, Baig JA, Afridi HI (2011) Correlation between arsenic concentration in fish and human scalp hair of people living in arsenic-contaminated and noncontaminated areas of Pakistan. Bio Trace Element Res 144:197–204 Shah AQ, Kazi TG, Baig JA, Afridi HI (2011) Correlation between arsenic concentration in fish and human scalp hair of people living in arsenic-contaminated and noncontaminated areas of Pakistan. Bio Trace Element Res 144:197–204
Zurück zum Zitat Shah MH, Shaheen N (2007) Statistical analysis of atmospheric trace metals and particulate fractions in Islamabad, Pakistan. J Hazard Mater 147:759–767 Shah MH, Shaheen N (2007) Statistical analysis of atmospheric trace metals and particulate fractions in Islamabad, Pakistan. J Hazard Mater 147:759–767
Zurück zum Zitat Shah MH, Shaheen M (2008) Annual and seasonal variations of trace metals in atmospheric suspended particulate matter in Islamabad, Pakistan. Water Air Soil Pollut 190:13–25 Shah MH, Shaheen M (2008) Annual and seasonal variations of trace metals in atmospheric suspended particulate matter in Islamabad, Pakistan. Water Air Soil Pollut 190:13–25
Zurück zum Zitat Shah MT, Begum S, Khan S (2010) Pedo and biogeochemical studies of mafic and ultramafic rocks in the Mingora and Kabal areas, Swat, Pakistan. Environ Earth Sci 60:1091–1102 Shah MT, Begum S, Khan S (2010) Pedo and biogeochemical studies of mafic and ultramafic rocks in the Mingora and Kabal areas, Swat, Pakistan. Environ Earth Sci 60:1091–1102
Zurück zum Zitat Shah MT, Ara J, Muhammad S, Khan S, Tariq S (2012) Health risk assessment via surface water and sub-surface water consumption in the mafic and ultramafic terrain, Mohmand agency, northern Pakistan. J Geochem Explor 118:60–67 Shah MT, Ara J, Muhammad S, Khan S, Tariq S (2012) Health risk assessment via surface water and sub-surface water consumption in the mafic and ultramafic terrain, Mohmand agency, northern Pakistan. J Geochem Explor 118:60–67
Zurück zum Zitat Shan UA, Ikram N (2012) Heavy metals in human scalp hair and nail samples from Pakistan: influence of working and smoking habits. Int J Chem Biochem Sci 1:54–58 Shan UA, Ikram N (2012) Heavy metals in human scalp hair and nail samples from Pakistan: influence of working and smoking habits. Int J Chem Biochem Sci 1:54–58
Zurück zum Zitat Sharif M, Nergis Y, Farooq MA (2010) Soil contamination of toxic elements irrigated with mixed industrial effluent and its environmental impact on urban area of Karachi, Pakistan. Am Eurasian J Agric Environ Sci 9:584–591 Sharif M, Nergis Y, Farooq MA (2010) Soil contamination of toxic elements irrigated with mixed industrial effluent and its environmental impact on urban area of Karachi, Pakistan. Am Eurasian J Agric Environ Sci 9:584–591
Zurück zum Zitat Sharmaa RK, Agrawala M, Marshall F (2007) Heavy metal contamination of soil and vegetables in suburban areas of Varanasi, India. Ecotox Environ Safe 66:258–266 Sharmaa RK, Agrawala M, Marshall F (2007) Heavy metal contamination of soil and vegetables in suburban areas of Varanasi, India. Ecotox Environ Safe 66:258–266
Zurück zum Zitat Sial RA, Chaudhary MF, Abbas ST, Latif MI, Khan AG (2006) Quality of effluents from Hattar Industrial Estate. J Zhejiang Uni Sci B 7:974–980 Sial RA, Chaudhary MF, Abbas ST, Latif MI, Khan AG (2006) Quality of effluents from Hattar Industrial Estate. J Zhejiang Uni Sci B 7:974–980
Zurück zum Zitat Siddiqui S, Khattak RA (2012) Heavy metals distribution in the soils of Peshawar valley Northern Pakistan. Sci Res Ess 7:544–552 Siddiqui S, Khattak RA (2012) Heavy metals distribution in the soils of Peshawar valley Northern Pakistan. Sci Res Ess 7:544–552
Zurück zum Zitat Singh S, Kumar M (2006) Heavy metal load of soil, water and vegetables in Peri-Urban Delhi. Environ Monit Assess 120(1–3):79–91 Singh S, Kumar M (2006) Heavy metal load of soil, water and vegetables in Peri-Urban Delhi. Environ Monit Assess 120(1–3):79–91
Zurück zum Zitat Smith AH, Hopenhayn-Rich C, Bates MN, Goeden HM, Hertz-Picciotto I, Duggan HM, Wood R, Kosnett MJ, Smith MT (1992) Cancer risks from arsenic in drinking water. Environ Health Perspect 97:259–267 Smith AH, Hopenhayn-Rich C, Bates MN, Goeden HM, Hertz-Picciotto I, Duggan HM, Wood R, Kosnett MJ, Smith MT (1992) Cancer risks from arsenic in drinking water. Environ Health Perspect 97:259–267
Zurück zum Zitat Solomons NW, Ruz M (1998) Trace element requirements in humans: an update. J Trace Elem Exp Med 11:177–195 Solomons NW, Ruz M (1998) Trace element requirements in humans: an update. J Trace Elem Exp Med 11:177–195
Zurück zum Zitat State of the Environment, report (2005) Draft report. Ministry Environ Govt Pakistan State of the Environment, report (2005) Draft report. Ministry Environ Govt Pakistan
Zurück zum Zitat Stein JA, Tschudy DP, Coroan PC, Coffins A (1999) Metal pollution. Biol Chem, 245–253 Stein JA, Tschudy DP, Coroan PC, Coffins A (1999) Metal pollution. Biol Chem, 245–253
Zurück zum Zitat Tariq J, Jaffar M, Ashraf M (1994) Trace metal concentration, distribution and correlation in water, sediment and fish from the Ravi River, Pakistan. Fish Res 19:131–139 Tariq J, Jaffar M, Ashraf M (1994) Trace metal concentration, distribution and correlation in water, sediment and fish from the Ravi River, Pakistan. Fish Res 19:131–139
Zurück zum Zitat Tariq MI, Afza S, Hussain I (2006a) Degradation and persistence of cotton pesticides in sandy loam soils from Punjab, Pakistan. Environ Res 100:184–196 Tariq MI, Afza S, Hussain I (2006a) Degradation and persistence of cotton pesticides in sandy loam soils from Punjab, Pakistan. Environ Res 100:184–196
Zurück zum Zitat Tariq SR, Shah MH, Shaheen N, Jaffar M, Khalique A (2008) Statistical source identification of metals in groundwater exposed to industrial contamination. Environ Monit Assess 138:159–165 Tariq SR, Shah MH, Shaheen N, Jaffar M, Khalique A (2008) Statistical source identification of metals in groundwater exposed to industrial contamination. Environ Monit Assess 138:159–165
Zurück zum Zitat Tariq M, Ali M, Shah Z (2006b) Characteristics of industrial effluents and their possible impacts on quality of underground water. Soil Environ 25:64–69 Tariq M, Ali M, Shah Z (2006b) Characteristics of industrial effluents and their possible impacts on quality of underground water. Soil Environ 25:64–69
Zurück zum Zitat Toor IA, Tahir SNA (2009) Study of arsenic concentration levels in Pakistani drinking water. Polish J Environ Stud 18:907–912 Toor IA, Tahir SNA (2009) Study of arsenic concentration levels in Pakistani drinking water. Polish J Environ Stud 18:907–912
Zurück zum Zitat Ullah R, Malik RN, Qadir A (2009) Assessment of groundwater contamination in an industrial city, Sialkot, Pakistan. Afr J Environ Sci Technol 3:429–446 Ullah R, Malik RN, Qadir A (2009) Assessment of groundwater contamination in an industrial city, Sialkot, Pakistan. Afr J Environ Sci Technol 3:429–446
Zurück zum Zitat Ullah Z, Khan H, Waseem A, Mahmood Q, Farooq U (2013) Water quality assessment of the River Kabul at Peshawar, Pakistan: industrial and urban wastewater impacts. J Water Chem Tech 35:170–176 Ullah Z, Khan H, Waseem A, Mahmood Q, Farooq U (2013) Water quality assessment of the River Kabul at Peshawar, Pakistan: industrial and urban wastewater impacts. J Water Chem Tech 35:170–176
Zurück zum Zitat Umar M, Waseem A, Sabir MA, Kassi AM, Khan AS (2013) The impact of geology of recharge areas on groundwater quality: a case study of Zhob River Basin, Pakistan. Clean–Soil, Air, Water 2:119–127 Umar M, Waseem A, Sabir MA, Kassi AM, Khan AS (2013) The impact of geology of recharge areas on groundwater quality: a case study of Zhob River Basin, Pakistan. Clean–Soil, Air, Water 2:119–127
Zurück zum Zitat United Nations Industrial Development Organization (UNIDO) (2000) Industrial policy and the environment in Pakistan. UNIDO, Vienna, Austria United Nations Industrial Development Organization (UNIDO) (2000) Industrial policy and the environment in Pakistan. UNIDO, Vienna, Austria
Zurück zum Zitat USEPA (US Environmental Protection Agency) (1997) Exposure factors handbook. Volume II–food ingestion factors. Office of Research and Development, Washington, DC, EPA/600//P-95/002Fa. http://www.epa.gov/superfund/health/conmedia/soil/index.htm. http://www.epa.gov/region9/superfund/prg/ USEPA (US Environmental Protection Agency) (1997) Exposure factors handbook. Volume II–food ingestion factors. Office of Research and Development, Washington, DC, EPA/600//P-95/002Fa. http://​www.​epa.​gov/​superfund/​health/​conmedia/​soil/​index.​htm.​ http://www.epa.gov/region9/superfund/prg/
Zurück zum Zitat USEPA (2002) Supplemental guidance for developing soil screening levels for superfund sites. Office of Solid Waste and Emergency Response, Washington, DC [OSWER 9355.4-24] USEPA (2002) Supplemental guidance for developing soil screening levels for superfund sites. Office of Solid Waste and Emergency Response, Washington, DC [OSWER 9355.4-24]
Zurück zum Zitat Verkleji JAS (1993) The effects of heavy metals stress on higher plants and their use as bio monitors. In: Markert B (ed) Plant as bioindicators: indicators of heavy metals in the terrestrial environment. VCH, New York, pp 415–424 Verkleji JAS (1993) The effects of heavy metals stress on higher plants and their use as bio monitors. In: Markert B (ed) Plant as bioindicators: indicators of heavy metals in the terrestrial environment. VCH, New York, pp 415–424
Zurück zum Zitat Waalkes MP, Rehm S, Riggs CW, Bare RM, Devor DE, Poirier LA (1988) Cadmium carcinogenesis in male Wistar [Crl:(WI) BR] rats: dose-response analysis of tumor induction in the prostate and testes and at the injection site. Cancer Res 48:4656–4663 Waalkes MP, Rehm S, Riggs CW, Bare RM, Devor DE, Poirier LA (1988) Cadmium carcinogenesis in male Wistar [Crl:(WI) BR] rats: dose-response analysis of tumor induction in the prostate and testes and at the injection site. Cancer Res 48:4656–4663
Zurück zum Zitat Wadhwa SK, Kazi TG, Afridi HI, Talpur FN, Naeemullah (2015) Interaction between carcinogenic and anti-carcinogenic trace elements in the scalp hair samples of different types of Pakistani female cancer patients. Clinica Chimica Acta 439:178–184 Wadhwa SK, Kazi TG, Afridi HI, Talpur FN, Naeemullah (2015) Interaction between carcinogenic and anti-carcinogenic trace elements in the scalp hair samples of different types of Pakistani female cancer patients. Clinica Chimica Acta 439:178–184
Zurück zum Zitat Wang XL, Sato T, Xing BS, Tao S (2005) Health risks of heavy metals to the general public in Tianjin, China via consumption of vegetables and fish. Sci Total Environ 350:28–37 Wang XL, Sato T, Xing BS, Tao S (2005) Health risks of heavy metals to the general public in Tianjin, China via consumption of vegetables and fish. Sci Total Environ 350:28–37
Zurück zum Zitat Wei B, Yang L (2010) A review of heavy metal contaminations in urban soils, urban road dusts and agricultural soils from China. Microchem J 94(2):99–107 Wei B, Yang L (2010) A review of heavy metal contaminations in urban soils, urban road dusts and agricultural soils from China. Microchem J 94(2):99–107
Zurück zum Zitat Weiss L, Wright S (2001) Mercury on the road to zero. Recommended strategies to eliminate mercury releases from human activities in Oregon by 2020. Oregon Environmental Council & The Mercury Solution Team, Oregon Weiss L, Wright S (2001) Mercury on the road to zero. Recommended strategies to eliminate mercury releases from human activities in Oregon by 2020. Oregon Environmental Council & The Mercury Solution Team, Oregon
Zurück zum Zitat WHO (1999) Air quality guidelines for Europe, 2nd edn. World Health Organization Regional Office for Europe. World Health Organization, Copenhagen WHO (1999) Air quality guidelines for Europe, 2nd edn. World Health Organization Regional Office for Europe. World Health Organization, Copenhagen
Zurück zum Zitat WHO (2007) Health risks of heavy metals from long range trans boundary air pollution, DK-2100 Copenhagen 0. World Health Organization, Denmark WHO (2007) Health risks of heavy metals from long range trans boundary air pollution, DK-2100 Copenhagen 0. World Health Organization, Denmark
Zurück zum Zitat Wiwatanadate P, Liwsrisakun C (2011) Acute effects of air pollution on peak expiratory flow rates and symptoms among asthmatic patients in Chiang Mai, Thailand. Int J Hygiene Environ Health 214:251–257 Wiwatanadate P, Liwsrisakun C (2011) Acute effects of air pollution on peak expiratory flow rates and symptoms among asthmatic patients in Chiang Mai, Thailand. Int J Hygiene Environ Health 214:251–257
Zurück zum Zitat Wongsasuluk P, Chotpantarat S, Siriwong W, Robson M (2013) Heavy metal contamination and human health risk assessment in drinking water from shallow groundwater wells in an agricultural area in Ubon Ratchathani province, Thailand. Environ Geochem Health 36:169–182 Wongsasuluk P, Chotpantarat S, Siriwong W, Robson M (2013) Heavy metal contamination and human health risk assessment in drinking water from shallow groundwater wells in an agricultural area in Ubon Ratchathani province, Thailand. Environ Geochem Health 36:169–182
Zurück zum Zitat WWF-Pak (2007) Report on National Surface Water Classification Criteria, Irrigation water quality guidelines for Pakistan. February-2007. World Wide Fund Pakistan WWF-Pak (2007) Report on National Surface Water Classification Criteria, Irrigation water quality guidelines for Pakistan. February-2007. World Wide Fund Pakistan
Zurück zum Zitat Xia X, Chen X, Liu R, Liu H (2011) Heavy metals in urban soils with various types of land use in Beijing. J Hazard Mater 186:2043–2050 Xia X, Chen X, Liu R, Liu H (2011) Heavy metals in urban soils with various types of land use in Beijing. J Hazard Mater 186:2043–2050
Zurück zum Zitat Yousafzai AHK, Hashmi DR, Qaimkhani MI, Ahmad F, Siddiqui I (2001) Determination of heavy metals in vegetables and soils at sewerage farm in Sindh industrial trading estate (SITE), Karachi. J Chem Soc Pak, 23 Yousafzai AHK, Hashmi DR, Qaimkhani MI, Ahmad F, Siddiqui I (2001) Determination of heavy metals in vegetables and soils at sewerage farm in Sindh industrial trading estate (SITE), Karachi. J Chem Soc Pak, 23
Zurück zum Zitat Zafar A, Eqani SAMAS, Cincinelli NBA, Tahir F, Shah STA, Hussain A, Alamdar A, Huang Q, Peng S, Shen H (2014) Toxic metals signature in the human seminal plasma of Pakistani population and their potential role in male infertility. Environ Geochem Health. doi:10.1007/s10653-014-9666-8CrossRef Zafar A, Eqani SAMAS, Cincinelli NBA, Tahir F, Shah STA, Hussain A, Alamdar A, Huang Q, Peng S, Shen H (2014) Toxic metals signature in the human seminal plasma of Pakistani population and their potential role in male infertility. Environ Geochem Health. doi:10.​1007/​s10653-014-9666-8CrossRef
Metadaten
Titel
Toxic Metal Pollution in Pakistan and Its Possible Risks to Public Health
verfasst von
Shakirullah Khan Shakir
Azizullah Azizullah
Waheed Murad
Muhammad K. Daud
Farhat Nabeela
Hazir Rahman
Shafiq ur Rehman
Donat-Peter Häder
Copyright-Jahr
2017
DOI
https://doi.org/10.1007/398_2016_9