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Erschienen in:
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2020 | OriginalPaper | Buchkapitel

Transcranial Dynamic Fluorescence Imaging for the Study of the Epileptic Seizures

verfasst von : Vyacheslav Kalchenko, Alon Harmelin, David Israeli, Babak Kateb, Igor Meglinski, Qinggong Tang, Nitish V. Thakor, Alla Ignashchenkova, Anna Volnova, Vassiliy Tsytsarev

Erschienen in: Functional Brain Mapping: Methods and Aims

Verlag: Springer Singapore

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Abstract

In last decade functional brain mapping has made significant strides through development of advanced methods, culminating into revolutionary diagnostic imaging and therapeutic applications of neurophotonics. Imaging technologies include intrinsic optical imaging, voltage-sensitive dye, photoacoustic, optical coherence tomography, multi-spectral imaging, UV, yellow light, thermal and near-infrared spectroscopy. Some of these technologies are not only used in animal studies of the model of epileptic seizures but also been in clinical trials. However, translation of such basic science application of brain mapping technologies into clinical setting remains challenging. In this paper we review current advances in the field, along with one clear focus on laser speckle contrast imaging and its application in epilepsy. Our conclusion is that functional brain optical imaging could play a key role in bridging between morphology and functional activity of the brain, and thus contribute to more accurate diagnostics and improved efficacy of the therapy. Coupling brain optical imaging with measurements of disease biomarkers and adding as well as other neuroscience techniques is making early diagnosis more effective and applicable for variable clinical tasks.

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Vorheriges Kapitel Neurons and Plasticity: What Do Glial Cells Have to Do with This?
Nächstes Kapitel Critical Elements for Connectivity Analysis of Brain Networks
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Metadaten
Titel
Transcranial Dynamic Fluorescence Imaging for the Study of the Epileptic Seizures
verfasst von
Vyacheslav Kalchenko
Alon Harmelin
David Israeli
Babak Kateb
Igor Meglinski
Qinggong Tang
Nitish V. Thakor
Alla Ignashchenkova
Anna Volnova
Vassiliy Tsytsarev
Copyright-Jahr
2020
Verlag
Springer Singapore
Buch
Functional Brain Mapping: Methods and Aims

Print ISBN: 978-981-15-6882-4

Electronic ISBN: 978-981-15-6883-1

Copyright-Jahr: 2020

DOI
https://doi.org/10.1007/978-981-15-6883-1_3