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Published in:
2011 | OriginalPaper | Chapter
A Customized Dot Plot Analysis for Alpha Satellite DNA Localization
Authors : G. P. Pop, A. Voina, E. Onaca
Published in: International Conference on Advancements of Medicine and Health Care through Technology
Publisher: Springer Berlin Heidelberg
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Numerical representation of genomic signals is very important as many of the methods for detecting repeated sequences are part of the digital signal processing field. An original nucleotide sequence representation and a mapping algorithm are used to provide a single numerical sequence for DNA repeats detection which includes information about repeats length. A customized dot plot analysis was used to estimate position of repeats, using two methods of estimating similarity between numerical subsequences. These approaches were combined to isolate position and length of DNA repeats from human alpha satellite DNA.