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2020 | OriginalPaper | Chapter

A Semantically Flexible Feature Fusion Network for Retinal Vessel Segmentation

Authors : Tariq M. Khan, Antonio Robles-Kelly, Syed S. Naqvi

Published in: Neural Information Processing

Publisher: Springer International Publishing

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Abstract

The automatic detection of retinal blood vessels by computer aided techniques plays an important role in the diagnosis of diabetic retinopathy, glaucoma, and macular degeneration. In this paper we present a semantically flexible feature fusion network that employs residual skip connections between adjacent neurons to improve retinal vessel detection. This yields a method that can be trained employing residual learning. To illustrate the utility of our method for retinal blood vessel detection, we show results on two publicly available data sets, i.e. DRIVE and STARE. In our experimental evaluation we include widely used evaluation metrics and compare our results with those yielded by alternatives elsewhere in the literature. In our experiments, our method is quite competitive, delivering a margin of sensitivity and accuracy improvement as compared to the alternatives under consideration.

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Literature
1.
go back to reference Khawaja, A., Khan, T.M., Khan, M.A.U., Nawaz, S.J.: A multi-scale directional line detector for retinal vessel segmentation. Sensors 19(22), 4949 (2019)CrossRef Khawaja, A., Khan, T.M., Khan, M.A.U., Nawaz, S.J.: A multi-scale directional line detector for retinal vessel segmentation. Sensors 19(22), 4949 (2019)CrossRef
2.
go back to reference Khawaja, A., Khan, T.M., Naveed, K., Naqvi, S.S., Rehman, N.U., Junaid Nawaz, S.: An improved retinal vessel segmentation framework using frangi filter coupled with the probabilistic patch based denoiser. IEEE Access 7, 164344–164361 (2019)CrossRef Khawaja, A., Khan, T.M., Naveed, K., Naqvi, S.S., Rehman, N.U., Junaid Nawaz, S.: An improved retinal vessel segmentation framework using frangi filter coupled with the probabilistic patch based denoiser. IEEE Access 7, 164344–164361 (2019)CrossRef
3.
go back to reference Klein, R., Klein, B.E., Moss, S.E.: Visual impairment in diabetes. Ophthalmology 91(1), 1–9 (1984)CrossRef Klein, R., Klein, B.E., Moss, S.E.: Visual impairment in diabetes. Ophthalmology 91(1), 1–9 (1984)CrossRef
4.
go back to reference Soomro, T.A., Khan, T.M., Khan, M.A.U., Gao, J., Paul, M., Zheng, L.: Impact of ICA-based image enhancement technique on retinal blood vessels segmentation. IEEE Access 6, 3524–3538 (2018)CrossRef Soomro, T.A., Khan, T.M., Khan, M.A.U., Gao, J., Paul, M., Zheng, L.: Impact of ICA-based image enhancement technique on retinal blood vessels segmentation. IEEE Access 6, 3524–3538 (2018)CrossRef
5.
go back to reference Zhang, J., Li, H., Nie, Q., Cheng, L.: A retinal vessel boundary tracking method based on Bayesian theory and multi-scale line detection. Comput. Med. Imag. Graph. 38(6), 517–525 (2014)CrossRef Zhang, J., Li, H., Nie, Q., Cheng, L.: A retinal vessel boundary tracking method based on Bayesian theory and multi-scale line detection. Comput. Med. Imag. Graph. 38(6), 517–525 (2014)CrossRef
6.
go back to reference Memari, N., Saripan, M.I.B., Mashohor, S., Moghbel, M.: Retinal blood vessel segmentation by using matched filtering and fuzzy c-means clustering with integrated level set method for diabetic retinopathy assessment. J. Med. Biol. Eng. 1–19 (2018) Memari, N., Saripan, M.I.B., Mashohor, S., Moghbel, M.: Retinal blood vessel segmentation by using matched filtering and fuzzy c-means clustering with integrated level set method for diabetic retinopathy assessment. J. Med. Biol. Eng. 1–19 (2018)
7.
go back to reference Almotiri, J., Elleithy, K., Elleithy, A.: Retinal vessels segmentation techniques and algorithms: a survey. Appl. Sci. 8, 01 (2018)CrossRef Almotiri, J., Elleithy, K., Elleithy, A.: Retinal vessels segmentation techniques and algorithms: a survey. Appl. Sci. 8, 01 (2018)CrossRef
8.
go back to reference Thakoor, K.A., Li, X., Tsamis, E., Sajda, P., Hood, D.C.: Enhancing the accuracy of glaucoma detection from oct probability maps using convolutional neural networks. In: International Conference of the IEEE Engineering in Medicine and Biology Society, pp. 2036–2040 (2019) Thakoor, K.A., Li, X., Tsamis, E., Sajda, P., Hood, D.C.: Enhancing the accuracy of glaucoma detection from oct probability maps using convolutional neural networks. In: International Conference of the IEEE Engineering in Medicine and Biology Society, pp. 2036–2040 (2019)
9.
go back to reference Zeng, X., Chen, H., Luo, Y., Ye, W.: Automated diabetic retinopathy detection based on binocular siamese-like convolutional neural network. IEEE Access 7, 30 744–30 753 (2019) Zeng, X., Chen, H., Luo, Y., Ye, W.: Automated diabetic retinopathy detection based on binocular siamese-like convolutional neural network. IEEE Access 7, 30 744–30 753 (2019)
10.
go back to reference Muraoka, Y., et al.: Morphologic and functional changes in retinal vessels associated with branch retinal vein occlusion. Ophthalmology 120(1), 91–99 (2013)CrossRef Muraoka, Y., et al.: Morphologic and functional changes in retinal vessels associated with branch retinal vein occlusion. Ophthalmology 120(1), 91–99 (2013)CrossRef
11.
go back to reference Cicinelli, M.V., et al.: Optical coherence tomography angiography in dry age-related macular degeneration. Surv. Ophthalmol. 63(2), 236–244 (2018)CrossRef Cicinelli, M.V., et al.: Optical coherence tomography angiography in dry age-related macular degeneration. Surv. Ophthalmol. 63(2), 236–244 (2018)CrossRef
12.
go back to reference Traustason, S., Jensen, A.S., Arvidsson, H.S., Munch, I.C., Søndergaard, L., Larsen, M.: Retinal oxygen saturation in patients with systemic hypoxemia. Invest. Ophthalmol. Vis. Sci. 52(8), 5064 (2011)CrossRef Traustason, S., Jensen, A.S., Arvidsson, H.S., Munch, I.C., Søndergaard, L., Larsen, M.: Retinal oxygen saturation in patients with systemic hypoxemia. Invest. Ophthalmol. Vis. Sci. 52(8), 5064 (2011)CrossRef
13.
go back to reference Jiang, Y., Tan, N., Peng, T.: Optic disc and cup segmentation based on deep convolutional generative adversarial networks. IEEE Access 7, 64 483–64 493 (2019) Jiang, Y., Tan, N., Peng, T.: Optic disc and cup segmentation based on deep convolutional generative adversarial networks. IEEE Access 7, 64 483–64 493 (2019)
14.
go back to reference Jiang, Y., Zhang, H., Tan, N., Chen, L.: Automatic retinal blood vessel segmentation based on fully convolutional neural networks. Symmetry 11, 1112 (2019) Jiang, Y., Zhang, H., Tan, N., Chen, L.: Automatic retinal blood vessel segmentation based on fully convolutional neural networks. Symmetry 11, 1112 (2019)
15.
go back to reference Zhou, Z., Siddiquee, M.M.R., Tajbakhsh, N., Liang, J.: Unet++: redesigning skip connections to exploit multiscale features in image segmentation. IEEE Trans. Med. Imaging 39(6), 1856–1867 (2020)CrossRef Zhou, Z., Siddiquee, M.M.R., Tajbakhsh, N., Liang, J.: Unet++: redesigning skip connections to exploit multiscale features in image segmentation. IEEE Trans. Med. Imaging 39(6), 1856–1867 (2020)CrossRef
16.
go back to reference Szegedy, C., Ioffe, S., Vanhoucke, V., Alemi, A.A.: Inception-v4, inception-resnet and the impact of residual connections on learning (2017) Szegedy, C., Ioffe, S., Vanhoucke, V., Alemi, A.A.: Inception-v4, inception-resnet and the impact of residual connections on learning (2017)
17.
go back to reference Ibtehaz, N., Rahman, M.S.: Multiresunet: rethinking the u-net architecture for multimodal biomedical image segmentation. Neural Netw. 121, 74–87 (2020)CrossRef Ibtehaz, N., Rahman, M.S.: Multiresunet: rethinking the u-net architecture for multimodal biomedical image segmentation. Neural Netw. 121, 74–87 (2020)CrossRef
18.
go back to reference Staal, J., Abramoff, M.D., Niemeijer, M., Viergever, M.A., van Ginneken, B.: Ridge-based vessel segmentation in color images of the retina. IEEE Trans. Med. Imaging 23(4), 501–509 (2004)CrossRef Staal, J., Abramoff, M.D., Niemeijer, M., Viergever, M.A., van Ginneken, B.: Ridge-based vessel segmentation in color images of the retina. IEEE Trans. Med. Imaging 23(4), 501–509 (2004)CrossRef
19.
go back to reference Hoover, A.D., Kouznetsova, V., Goldbaum, M.: Locating blood vessels in retinal images by piecewise threshold probing of a matched filter response. IEEE Trans. Med. Imaging 19(3), 203–210 (2000)CrossRef Hoover, A.D., Kouznetsova, V., Goldbaum, M.: Locating blood vessels in retinal images by piecewise threshold probing of a matched filter response. IEEE Trans. Med. Imaging 19(3), 203–210 (2000)CrossRef
20.
go back to reference Li, Q., Feng, B., Xie, L., Liang, P., Zhang, H., Wang, T.: A cross-modality learning approach for vessel segmentation in retinal images. IEEE Trans. Med. Imaging 35(1), 109–118 (2016)CrossRef Li, Q., Feng, B., Xie, L., Liang, P., Zhang, H., Wang, T.: A cross-modality learning approach for vessel segmentation in retinal images. IEEE Trans. Med. Imaging 35(1), 109–118 (2016)CrossRef
21.
go back to reference Orlando, J.I., Prokofyeva, E., Blaschko, M.B.: A discriminatively trained fully connected conditional random field model for blood vessel segmentation in fundus images. IEEE Trans. Biomed. Eng. 64(1), 16–27 (2016)CrossRef Orlando, J.I., Prokofyeva, E., Blaschko, M.B.: A discriminatively trained fully connected conditional random field model for blood vessel segmentation in fundus images. IEEE Trans. Biomed. Eng. 64(1), 16–27 (2016)CrossRef
22.
go back to reference Dasgupta, A., Singh, S.: A fully convolutional neural network based structured prediction approach towards the retinal vessel segmentation. In: International Symposium on Biomedical Imaging, pp. 248–251 (2017) Dasgupta, A., Singh, S.: A fully convolutional neural network based structured prediction approach towards the retinal vessel segmentation. In: International Symposium on Biomedical Imaging, pp. 248–251 (2017)
23.
go back to reference Yan, Z., Yang, X., Cheng, K.T.: Joint segment-level and pixel-wise losses for deep learning based retinal vessel segmentation. IEEE Trans. Biomed. Eng. 1 (2018) Yan, Z., Yang, X., Cheng, K.T.: Joint segment-level and pixel-wise losses for deep learning based retinal vessel segmentation. IEEE Trans. Biomed. Eng. 1 (2018)
24.
go back to reference Jiang, Y., Tan, N., Peng, T., Zhang, H.: Retinal vessels segmentation based on dilated multi-scale convolutional neural network. IEEE Access 7, 76 342–76 352 (2019) Jiang, Y., Tan, N., Peng, T., Zhang, H.: Retinal vessels segmentation based on dilated multi-scale convolutional neural network. IEEE Access 7, 76 342–76 352 (2019)
25.
go back to reference Adapa, D., et al.: A supervised blood vessel segmentation technique for digital fundus images using zernike moment based features. PLOS ONE 15(3), 1–23 (2020) Adapa, D., et al.: A supervised blood vessel segmentation technique for digital fundus images using zernike moment based features. PLOS ONE 15(3), 1–23 (2020)
26.
go back to reference Zhang, J., Dashtbozorg, B., Bekkers, E., Pluim, J.P.W., Duits, R., Romeny, B.M.: Robust retinal vessel segmentation via locally adaptive derivative frames in orientation scores. IEEE Trans. Med. Imaging 35(12), 2631–2644 (2016)CrossRef Zhang, J., Dashtbozorg, B., Bekkers, E., Pluim, J.P.W., Duits, R., Romeny, B.M.: Robust retinal vessel segmentation via locally adaptive derivative frames in orientation scores. IEEE Trans. Med. Imaging 35(12), 2631–2644 (2016)CrossRef
27.
go back to reference Soomro, T.A., Afifi, A.J., Gao, J., Hellwich, O., Zheng, L., Paul, M.: Strided fully convolutional neural network for boosting the sensitivity of retinal blood vessels segmentation. Expert Syst. Appl. 134, 36–52 (2019)CrossRef Soomro, T.A., Afifi, A.J., Gao, J., Hellwich, O., Zheng, L., Paul, M.: Strided fully convolutional neural network for boosting the sensitivity of retinal blood vessels segmentation. Expert Syst. Appl. 134, 36–52 (2019)CrossRef
Metadata
Title
A Semantically Flexible Feature Fusion Network for Retinal Vessel Segmentation
Authors
Tariq M. Khan
Antonio Robles-Kelly
Syed S. Naqvi
Copyright Year
2020
DOI
https://doi.org/10.1007/978-3-030-63820-7_18

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