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2018 | OriginalPaper | Chapter

A Workbench for Biomedical Applications Based on Image Analysis

Authors : Carlos Borau, Cristina del Amo, Jesús Asín, Nieves Movilla, Mar Cóndor, José Manuel García-Aznar

Published in: VipIMAGE 2017

Publisher: Springer International Publishing

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Abstract

Unraveling the underlying mechanisms involved in single and collective cell migration, organization, tissue formation and regeneration are some of the currently spearheading research topics worldwide. To overcome the intrinsic difficulties associated to realistic environments in 3D, a multidisciplinary framework combining computer simulations and experiments is proposed. The success of this approach relies on result validation (quantitative comparison: computational vs. experimental), so we have polished different techniques and computational tools to get as accurate measurements as possible. For that, we take advantage of our own designed microfluidic devices and perform thorough image and statistical analyses.

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Literature
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go back to reference del Amo, C., Borau, C., Gutiérrez, R., Asín, J., García-Aznar, J.M.: Quantification of angiogenic sprouting under different growth factors in a mi-crofluidic platform. J. Biomech. 49(8), 1340–1346 (2015) del Amo, C., Borau, C., Gutiérrez, R., Asín, J., García-Aznar, J.M.: Quantification of angiogenic sprouting under different growth factors in a mi-crofluidic platform. J. Biomech. 49(8), 1340–1346 (2015)
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go back to reference del Amo, C., Borau, C., Movilla, N., Asín, J., García-Aznar, J.M.: Quantifying 3D chemotaxis in microfluidic-based chips with step gradients of collagen hydrogel concentrations. Integr. Biol. 9(4), 339–349 (2017)CrossRef del Amo, C., Borau, C., Movilla, N., Asín, J., García-Aznar, J.M.: Quantifying 3D chemotaxis in microfluidic-based chips with step gradients of collagen hydrogel concentrations. Integr. Biol. 9(4), 339–349 (2017)CrossRef
Metadata
Title
A Workbench for Biomedical Applications Based on Image Analysis
Authors
Carlos Borau
Cristina del Amo
Jesús Asín
Nieves Movilla
Mar Cóndor
José Manuel García-Aznar
Copyright Year
2018
DOI
https://doi.org/10.1007/978-3-319-68195-5_59