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2017 | OriginalPaper | Chapter

Abnormal Brain Activity in ADHD: A Study of Resting-State fMRI

Authors : Chao Tang, Yuqing Wei, Jiajia Zhao, Xin Zhang, Jingxin Nie

Published in: Brain Informatics

Publisher: Springer International Publishing

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Abstract

The prevalence rate of ADHD varies from age to age. To better understand the development of ADHD from childhood to adolescence, different age groups of ADHD from large dataset are needed to explore the development pattern of brain activities. In this study, amplitude of low frequency fluctuation (ALFF), fractional amplitude of low frequency fluctuation (fALFF) and regional homogeneity (ReHo) were extracted from resting-state functional magnetic resonance imaging (rs-fMRI) of both ADHD subjects and typical developing (TD) subjects from 7 to 16 years old. The result showed that the different areas mainly appear at the bilateral superior frontal cortex, anterior cingulate cortex (ACC), precentral gyrus, right superior occipital lobe, cerebellum and parts of basal ganglia between all ADHD subjects and all TD subjects. Besides, compared with TD, there were different brain activity patterns at different ages in ADHD, which appear at the left ACC and left occipital lobe. The result can inspire more studies on comparisons between functional connectivity methods.

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Title: Abnormal Brain Activity in ADHD: A Study of Resting-State fMRI
Authors: Chao Tang
Yuqing Wei
Jiajia Zhao
Xin Zhang
Jingxin Nie
Publisher: Springer International Publishing
Book: Brain Informatics
Print ISBN: 978-3-319-70771-6

Electronic ISBN: 978-3-319-70772-3

Copyright Year: 2017
DOI: https://doi.org/10.1007/978-3-319-70772-3_17

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