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Published in: Medical & Biological Engineering & Computing 4/2007

01-04-2007 | Original Article

Adaptive method for assessment of cerebrospinal fluid outflow conductance

Authors: Nina Andersson, Jan Malm, Urban Wiklund, Anders Eklund

Published in: Medical & Biological Engineering & Computing | Issue 4/2007

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Abstract

Outflow conductance (C out) is important for predicting shunt responsiveness in patients with suspected idiopathic adult hydrocephalus syndrome (IAHS). C out is determined by performing an infusion test into the cerebrospinal fluid system, and the reliability of the test is dependent on the measurement time. The objective of this study was to develop an adaptive signal analysis method to reduce the investigation time, by taking the individual intracranial pressure variations of the patient into consideration. The method was evaluated on 28 patients with suspected IAHS. The results from full time investigations (60 min) were compared to the results of the new algorithm. Applying the new adaptive method resulted in a reduction of mean investigation time by 14.3 ± 5.9 min (mean ± SD), p < 0.01. The reduction of reliability in the C out estimation was found clinically negligible. We thus recommend this adaptive method to be used when performing constant pressure infusion tests.

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Metadata
Title
Adaptive method for assessment of cerebrospinal fluid outflow conductance
Authors
Nina Andersson
Jan Malm
Urban Wiklund
Anders Eklund
Publication date
01-04-2007
Publisher
Springer-Verlag
Published in
Medical & Biological Engineering & Computing / Issue 4/2007
Print ISSN: 0140-0118
Electronic ISSN: 1741-0444
DOI
https://doi.org/10.1007/s11517-006-0157-7

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