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2024 | OriginalPaper | Chapter

Durchflussunterstützte Synthese von Heterocyclen über Mehrkomponentenreaktionen

Authors : Seger Van Mileghem, Cedrick Veryser, Wim M. De Borggraeve

Published in: Flow-Chemie für die Synthese von Heterocyclen

Publisher: Springer International Publishing

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Zusammenfassung

Mehrkomponentenreaktionen (MCRs) sind von großer Bedeutung in der organischen Synthese. Sie verringern oft die Anzahl der Syntheseschritte, da drei oder mehr Reaktanten in einem einzigen Schritt im Produkt eingebaut werden. Dies erhöht die Anzahl der kombinatorischen Optionen und ermöglicht effizientere Prozesse in kürzerer Zeit. Die Pharmaindustrie ist daher sehr an MCRs für den Aufbau von Bibliotheken interessiert. Infolgedessen wird das Gebiet intensiv untersucht, um chemische Prozesse zu verbessern und neue Arten von MCRs zu entdecken.

Die Kombination der Vorteile von Durchflusstechnologie und MCRs für die Heterocyclensynthese ist ein interessantes und spezialisiertes Feld. Dieses Kapitel dient als Übersicht über die Literatur zu diesem Thema ab 2010, bis die Literatur zu diesem Thema in einem Buchkapitel in dieser Buchreihe von Cukalovic et al. (Top Heterocycl Chem 23:161–198, 2010) überprüft wird.

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previous chapter Photochemische Synthese von Heterocyclen: Zusammenführung von Durchflussverarbeitung und Metall-katalysierten Photoredoxtransformationen mit sichtbarem Licht

next chapter Durchflussunterstützte Synthese von Heterocyclen bei hohen Temperaturen

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Title: Durchflussunterstützte Synthese von Heterocyclen über Mehrkomponentenreaktionen
Authors: Seger Van Mileghem
Cedrick Veryser
Wim M. De Borggraeve
Publisher: Springer International Publishing
Book: Flow-Chemie für die Synthese von Heterocyclen
Print ISBN: 978-3-031-51911-6

Electronic ISBN: 978-3-031-51912-3

Copyright Year: 2024
DOI: https://doi.org/10.1007/978-3-031-51912-3_3