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2013 | OriginalPaper | Chapter

9. Bio/CMOS Interfaces in Constant Bias

Author : Sandro Carrara

Published in: Bio/CMOS Interfaces and Co-Design

Publisher: Springer New York

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Abstract

In the case of metabolite detection, we saw in Chap.​ 8 how to design the “nano” and “bio” parts of our Bio/Nano/CMOS interface. In that chapter, we saw that we could observe several redox reactions involving hydrogen peroxide. We also saw that each redox occurred at a certain proper bias (Eqs. 8.3–8.5 in Chap.​ 8). These different reactions are very important because the hydrogen peroxide is generated in redox catalyzed by enzymes from the protein family of oxidases (Eq. 8.2 in Chap.​ 8). Thus, we can fix the bias potential across the interface at the proper values and monitor over time the presence of all the metabolites catalyzed by oxidases. The aim of this chapter is to show Bio/CMOS interfaces for constant bias detection of metabolites. The chapter focuses on the CMOS design of a system.

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Metadata
Title
Bio/CMOS Interfaces in Constant Bias
Author
Sandro Carrara
Copyright Year
2013
Publisher
Springer New York
Book
Bio/CMOS Interfaces and Co-Design

Print ISBN: 978-1-4614-4689-7

Electronic ISBN: 978-1-4614-4690-3

Copyright Year: 2013

DOI
https://doi.org/10.1007/978-1-4614-4690-3_9