Skip to main content
Top

2020 | OriginalPaper | Chapter

Biodegradation of Pharmaceuticals Belonging to the Group of Non-steroidal Anti-inflammatory and Analgesic Drugs Using Activated Sludge

Authors : Zofia Kiersnowska, Dobrochna Ginter-Kramarczyk, Izabela Kruszelnicka, Anna Zając-Woźnialis, Joanna Zembrzuska, Michał Michalkiewicz

Published in: Practical Aspects of Chemical Engineering

Publisher: Springer International Publishing

Activate our intelligent search to find suitable subject content or patents.

search-config
loading …

Abstract

The chapter presents the results of field studies confirming the presence of selected compounds from the group of non-steroidal anti-inflammatory drugs (NSAIDs) in the aquatic environment and in selected points of the technological process of the Central Wastewater Treatment Plant in Kozieglowy. The first stage examined the occurrence and distribution of concentrations of selected drugs (fenoprofen, ibuprofen, ketoprofen, naproxen, paracetamol and tolmetin) in the Warta river, in the area of the city Poznan. The second stage of the study allowed to estimate the types and concentrations of the above mentioned drugs on four sections of WWTP in Kozieglowy. The collection points included: the sewage pumping stations, denitrification chamber, nitrification chamber and drainage section of the sewage purified to the Warta river. Analysis of drug occurrence in the Warta river and their ability to decompose in WWTP in Kozieglowy, carried out under real conditions. Analysis of drug occurrence in the Warta river and their ability to decompose in WWTP in Kozieglowy, carried out under real conditions.

Dont have a licence yet? Then find out more about our products and how to get one now:

Springer Professional "Wirtschaft+Technik"

Online-Abonnement

Mit Springer Professional "Wirtschaft+Technik" erhalten Sie Zugriff auf:

  • über 102.000 Bücher
  • über 537 Zeitschriften

aus folgenden Fachgebieten:

  • Automobil + Motoren
  • Bauwesen + Immobilien
  • Business IT + Informatik
  • Elektrotechnik + Elektronik
  • Energie + Nachhaltigkeit
  • Finance + Banking
  • Management + Führung
  • Marketing + Vertrieb
  • Maschinenbau + Werkstoffe
  • Versicherung + Risiko

Jetzt Wissensvorsprung sichern!

Springer Professional "Technik"

Online-Abonnement

Mit Springer Professional "Technik" erhalten Sie Zugriff auf:

  • über 67.000 Bücher
  • über 390 Zeitschriften

aus folgenden Fachgebieten:

  • Automobil + Motoren
  • Bauwesen + Immobilien
  • Business IT + Informatik
  • Elektrotechnik + Elektronik
  • Energie + Nachhaltigkeit
  • Maschinenbau + Werkstoffe




 

Jetzt Wissensvorsprung sichern!

Literature
go back to reference Ashfaq, M., Khan, K.N., Ur Rehman, M.S., Mustafa, G., Nazar, M.F., Sun, Q., Iqbal, J., Mulla, S.I., Yu, C.-P.: Ecological risk assessment of pharmaceuticals in the receiving environment of pharmaceutical wastewater in Pakistan. Ecotoxicol. Environ. Saf. 136, 31–39 (2017)CrossRef Ashfaq, M., Khan, K.N., Ur Rehman, M.S., Mustafa, G., Nazar, M.F., Sun, Q., Iqbal, J., Mulla, S.I., Yu, C.-P.: Ecological risk assessment of pharmaceuticals in the receiving environment of pharmaceutical wastewater in Pakistan. Ecotoxicol. Environ. Saf. 136, 31–39 (2017)CrossRef
go back to reference Adamek, E., Jakubczyk, E., Baran, W., Makowski, A., Lipska, I., Ziemiańska, J., Sobczak, A.: Fotodegradacja wybranych leków przeciwzapalnych w środowisku wodnym. Proc. ECOpole 5(1), 147–153 (2011) Adamek, E., Jakubczyk, E., Baran, W., Makowski, A., Lipska, I., Ziemiańska, J., Sobczak, A.: Fotodegradacja wybranych leków przeciwzapalnych w środowisku wodnym. Proc. ECOpole 5(1), 147–153 (2011)
go back to reference Clara, M., Kreuzinger, N., Strenn, B., Gans, O., Kroiss, H.: The solids retention time – a suitable design parameter to evaluate the capacity of wastewater treatment plants to remove micropollutants. Water Res. 39, 97–106 (2005)CrossRef Clara, M., Kreuzinger, N., Strenn, B., Gans, O., Kroiss, H.: The solids retention time – a suitable design parameter to evaluate the capacity of wastewater treatment plants to remove micropollutants. Water Res. 39, 97–106 (2005)CrossRef
go back to reference Dymaczewski, Z.: Poradnik Eksploatatora Oczyszczalni Ścieków, praca zbiorowa, wyd. Polskie Zrzeszenie Inżynierów i Techników Sanitarnych Oddział Wielkopolski, Poznań (2011) Dymaczewski, Z.: Poradnik Eksploatatora Oczyszczalni Ścieków, praca zbiorowa, wyd. Polskie Zrzeszenie Inżynierów i Techników Sanitarnych Oddział Wielkopolski, Poznań (2011)
go back to reference Felis, E., Miksch, K., Sikora, J.: Występowanie i możliwości usuwania farmaceutyków w Polsce, Materiały konferencyjne, VII Ogólnopolska Sesja Popularnonaukowa,,,Środowisko a zdrowie - 2005”, Częstochowa (2005) Felis, E., Miksch, K., Sikora, J.: Występowanie i możliwości usuwania farmaceutyków w Polsce, Materiały konferencyjne, VII Ogólnopolska Sesja Popularnonaukowa,,,Środowisko a zdrowie - 2005”, Częstochowa (2005)
go back to reference Fent, K., Weston, A.A., Caminada, D.: Ecotoxicology of human pharmaceuticals. Aquat. Toxicol. 76, 122–159 (2006)CrossRef Fent, K., Weston, A.A., Caminada, D.: Ecotoxicology of human pharmaceuticals. Aquat. Toxicol. 76, 122–159 (2006)CrossRef
go back to reference Ginter-Kramarczyk, D., Zając, A., Kruszelnicka, I., Zembrzuska, J., Budnik, I.: Teraźniejszość i przyszłość produktów leczniczych w społeczeństwie i środowisku. Przemysł Chemiczny 92(5), 596–600 (2013) Ginter-Kramarczyk, D., Zając, A., Kruszelnicka, I., Zembrzuska, J., Budnik, I.: Teraźniejszość i przyszłość produktów leczniczych w społeczeństwie i środowisku. Przemysł Chemiczny 92(5), 596–600 (2013)
go back to reference Jenicek, P., Zabranska, J., Dohanyos, M.: The influence of anaerobic pretreatment on the nitrogen removal from biosynthetic pharmaceutical wastewaters. Anton. Leeuw. 69, 41–46 (1996)CrossRef Jenicek, P., Zabranska, J., Dohanyos, M.: The influence of anaerobic pretreatment on the nitrogen removal from biosynthetic pharmaceutical wastewaters. Anton. Leeuw. 69, 41–46 (1996)CrossRef
go back to reference Khetan, S.K., Collins, T.J.: Human pharmaceuticals in the aquatic environment: a challenge to green chemistry. Chem. Rev. 107, 2319–2364 (2007)CrossRef Khetan, S.K., Collins, T.J.: Human pharmaceuticals in the aquatic environment: a challenge to green chemistry. Chem. Rev. 107, 2319–2364 (2007)CrossRef
go back to reference Kimura, K., Hara, H., Watanabe, Y.: Elimination of selected pharmaceuticals by biosolids from municipal wastewater treatment plants: importance of modest pH change and degree of mineralization. Water Sci. Technol. 62, 5 (2010). IWA PublishingCrossRef Kimura, K., Hara, H., Watanabe, Y.: Elimination of selected pharmaceuticals by biosolids from municipal wastewater treatment plants: importance of modest pH change and degree of mineralization. Water Sci. Technol. 62, 5 (2010). IWA PublishingCrossRef
go back to reference Kocwa-Haluch, R., Woźniakiewicz, T.: Analiza mikroskopowa osadu czynnego i jej rola w kontroli procesu technologicznego oczyszczania ścieków, Środowisko. Czasopismo Techniczne wydawnictwo Politechniki Krakowskiej 6, 141–162 (2011) Kocwa-Haluch, R., Woźniakiewicz, T.: Analiza mikroskopowa osadu czynnego i jej rola w kontroli procesu technologicznego oczyszczania ścieków, Środowisko. Czasopismo Techniczne wydawnictwo Politechniki Krakowskiej 6, 141–162 (2011)
go back to reference Kosjek, T., Heath, E., Kompare, B.: Removal of pharmaceutical residues in a pilot wastewater treatment plant. Anal. Bioanal. Chem. 387(4), 1379–1387 (2007). Springer-VerlagCrossRef Kosjek, T., Heath, E., Kompare, B.: Removal of pharmaceutical residues in a pilot wastewater treatment plant. Anal. Bioanal. Chem. 387(4), 1379–1387 (2007). Springer-VerlagCrossRef
go back to reference Kujawa-Roeleveld., K., Schuman, K., Grotenhuis, K., Kragić, K., Mels, A., Zeeman, G.: Biodegradability of human pharmaceutically active compounds (PhAC) in biological systems treating source separated wastewater streams. In: Switch Scientific Meeting, Wageningen, The Netherlands (2008) Kujawa-Roeleveld., K., Schuman, K., Grotenhuis, K., Kragić, K., Mels, A., Zeeman, G.: Biodegradability of human pharmaceutically active compounds (PhAC) in biological systems treating source separated wastewater streams. In: Switch Scientific Meeting, Wageningen, The Netherlands (2008)
go back to reference Luo, Y., Guo, W., Ngo, H.-H., Nghiem, L.-D., Hai, F.-I., Zhang, J., Liang, S., Wang, X.C.: A review on the occurrence of micropollutants in the aquatic environment and their fate and removal during wastewater treatment. Sci. Total Environ. 619, 473–474 (2014) Luo, Y., Guo, W., Ngo, H.-H., Nghiem, L.-D., Hai, F.-I., Zhang, J., Liang, S., Wang, X.C.: A review on the occurrence of micropollutants in the aquatic environment and their fate and removal during wastewater treatment. Sci. Total Environ. 619, 473–474 (2014)
go back to reference Martín, J., Camacho-Munoz, D., Santos, J.L., Aparicio, I., Alonso, E.: Occurrence of pharmaceutical compounds in wastewater and sludge from wastewater treatment plants: Removal and ecotoxicological impact of wastewater discharges and sludge disposal. J. Hazard. Mater. 239–240, 40–47 (2012)CrossRef Martín, J., Camacho-Munoz, D., Santos, J.L., Aparicio, I., Alonso, E.: Occurrence of pharmaceutical compounds in wastewater and sludge from wastewater treatment plants: Removal and ecotoxicological impact of wastewater discharges and sludge disposal. J. Hazard. Mater. 239–240, 40–47 (2012)CrossRef
go back to reference Murdoch, R.W., Hay, A.G.: The biodegradation of ibuprofen to trihydroxyibuprofen in activated sludge and by Variovorax Ibu-1. Biodegradation 26, 105–113 (2015)CrossRef Murdoch, R.W., Hay, A.G.: The biodegradation of ibuprofen to trihydroxyibuprofen in activated sludge and by Variovorax Ibu-1. Biodegradation 26, 105–113 (2015)CrossRef
go back to reference Nakada, N., Tanishima, T., Shinoohara, H., Kiri, K., Takada, H.: Pharmaceutical chemicals and endocrine disrupters in municipal wastewater in Tokyo and their removal during activated sludge treatment. Water Res. 40, 3297–3303 (2006)CrossRef Nakada, N., Tanishima, T., Shinoohara, H., Kiri, K., Takada, H.: Pharmaceutical chemicals and endocrine disrupters in municipal wastewater in Tokyo and their removal during activated sludge treatment. Water Res. 40, 3297–3303 (2006)CrossRef
go back to reference Pereira, A.M., Silva, L.J., Meisel, L.M., Lino, C.M., Pena, A.: Environmental impact of pharmaceuticals from Portuguese wastewaters: geographical and seasonal occurrence, removal and risk assessment. Environ. Res. 136, 108–119 (2015)CrossRef Pereira, A.M., Silva, L.J., Meisel, L.M., Lino, C.M., Pena, A.: Environmental impact of pharmaceuticals from Portuguese wastewaters: geographical and seasonal occurrence, removal and risk assessment. Environ. Res. 136, 108–119 (2015)CrossRef
go back to reference Pereira, A.M., Silva, L.J., Meisel, L.M., Lino, C.M., Pena, A.: A critical evaluation of different parameters for estimating pharmaceutical exposure seeking an improved environmental risk assessment. Sci. Total Environ. 603–604, 226–236 (2017) Pereira, A.M., Silva, L.J., Meisel, L.M., Lino, C.M., Pena, A.: A critical evaluation of different parameters for estimating pharmaceutical exposure seeking an improved environmental risk assessment. Sci. Total Environ. 603–604, 226–236 (2017)
go back to reference Samaras, V.G., Stasinakis, A.S., Mamais, D., Thomaidis, N.S., Lekkas, T.D.: Fate of selected pharmaceuticals and synthetic endocrine disrupting compounds during wastewater treatment and sludge anaerobic digestion. J. Hazard. Mater. 244–245, 259–267 (2013)CrossRef Samaras, V.G., Stasinakis, A.S., Mamais, D., Thomaidis, N.S., Lekkas, T.D.: Fate of selected pharmaceuticals and synthetic endocrine disrupting compounds during wastewater treatment and sludge anaerobic digestion. J. Hazard. Mater. 244–245, 259–267 (2013)CrossRef
go back to reference Suarez, S., Lema, J.M., Omil, F.: Removal of Pharmaceutical and Personal Care Products (PPCPs) under nitrifying and denitrifying conditions. Water Res. 44, 3214–3224 (2010)CrossRef Suarez, S., Lema, J.M., Omil, F.: Removal of Pharmaceutical and Personal Care Products (PPCPs) under nitrifying and denitrifying conditions. Water Res. 44, 3214–3224 (2010)CrossRef
go back to reference Szymonik, A., Lach, J.: Zagrożenia środowiska wodnego obecnością środków farmaceutycznych. Inżynieria i Ochrona Środowiska 15(3), 249–263 (2012) Szymonik, A., Lach, J.: Zagrożenia środowiska wodnego obecnością środków farmaceutycznych. Inżynieria i Ochrona Środowiska 15(3), 249–263 (2012)
go back to reference Quintana, J.B., Weiss, S., Reemttsma, T.: Pathways and metabolites of microbial degradation of selected acidic pharmaceutical and their occurrence in municipal wastewater treated by a membrane bioreactor. Water Res. 39(12), 2654–2664 (2005)CrossRef Quintana, J.B., Weiss, S., Reemttsma, T.: Pathways and metabolites of microbial degradation of selected acidic pharmaceutical and their occurrence in municipal wastewater treated by a membrane bioreactor. Water Res. 39(12), 2654–2664 (2005)CrossRef
go back to reference Zając, A., Budnik, I., Zembrzuska, J., Kruszelnicka, I., Ginter-Kramarczyk, D.: Droga farmaceutyków w środowisku przyrodniczym na terenie województwa wielkopolskiego - źródła występowania, obecność, zagrożenia, Materiały konferencyjne z II studenckiej konferencji naukowej „Produkcja, ekonomia, zarządzanie, marketing i ochrona środowiska – jak to się robi w Wielkopolsce”, Gniezno (2013) Zając, A., Budnik, I., Zembrzuska, J., Kruszelnicka, I., Ginter-Kramarczyk, D.: Droga farmaceutyków w środowisku przyrodniczym na terenie województwa wielkopolskiego - źródła występowania, obecność, zagrożenia, Materiały konferencyjne z II studenckiej konferencji naukowej „Produkcja, ekonomia, zarządzanie, marketing i ochrona środowiska – jak to się robi w Wielkopolsce”, Gniezno (2013)
go back to reference Zając, A.: Effectiveness of removal of selected nonsteroidal anti-inflammatory drugs from wastewater by the activated sludge method, PhD thesis (2017) Zając, A.: Effectiveness of removal of selected nonsteroidal anti-inflammatory drugs from wastewater by the activated sludge method, PhD thesis (2017)
Metadata
Title
Biodegradation of Pharmaceuticals Belonging to the Group of Non-steroidal Anti-inflammatory and Analgesic Drugs Using Activated Sludge
Authors
Zofia Kiersnowska
Dobrochna Ginter-Kramarczyk
Izabela Kruszelnicka
Anna Zając-Woźnialis
Joanna Zembrzuska
Michał Michalkiewicz
Copyright Year
2020
DOI
https://doi.org/10.1007/978-3-030-39867-5_15