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2022 | OriginalPaper | Chapter

Biomechanical Aspects of in Vitro Fertilization

Authors : Liliya Batyuk, Anatoly Khalin, Natalia Kizilova

Published in: Biomechanics in Medicine, Sport and Biology

Publisher: Springer International Publishing

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Abstract

During the last decades, in vitro fertilization (IVF) became one of the most demanded reproductive technologies used for infertility treatment. Despite the significant efforts, the percentage of successful procedures remains moderate (<50%). It is shown, the percentage of successful IVF could be increased by a patient-specific embryo transfer based on the preliminary biomechanical and CFD analyses. A detailed review on different aspects of the IVF procedure is given. CFD simulations on the embryo transfer with tubular fluid and air bubble through a thin rigid tube (catheter) have been carried out. The following parameters were found to be the most influencing on the embryo transfer to the fundus: (i) the injection time IT, (ii) the distance of the catheter tip to fundus; (iii) the injected volume during the first stage; (iv) duration of the second stage; (v) the withdrawal speed at which the catheter is removed at the last stage; (vi) the volume replacement during catheter withdrawal. The IT, catheter load speed and cumulative shear stress over the particle during the IT were found the main prognostic factors of the IVF success.

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Metadata
Title
Biomechanical Aspects of in Vitro Fertilization
Authors
Liliya Batyuk
Anatoly Khalin
Natalia Kizilova
Copyright Year
2022
Book
Biomechanics in Medicine, Sport and Biology

Print ISBN: 978-3-030-86296-1

Electronic ISBN: 978-3-030-86297-8

Copyright Year: 2022

DOI
https://doi.org/10.1007/978-3-030-86297-8_1