Top

Journal of Nanoparticle Research

Published in:

01-07-2011 | Research paper

Biotoxicity of nanoparticles: effect of natural organic matter

Authors: Sungyun Lee, Kitae Kim, H. K. Shon, Sang Don Kim, Jaeweon Cho

Published in: Journal of Nanoparticle Research | Issue 7/2011

Activate our intelligent search to find suitable subject content or patents.

search-config

AI-assisted search

Off

Abstract

Various natural organic matters (NOM) with different characteristics in aquatic environment may affect toxicity of leased nanoparticles, owing to interactions between NOM and nanoparticles. This study investigated the effect of NOM and physical characteristics of the effluent organic matter (EfOM) on the ecotoxicity of quantum dots (QD) using Daphnia magna. Organic matter samples were obtained from: Yeongsan River (YR-NOM), Dongbuk Lake (DL-NOM), Damyang wastewater treatment plant (EfOM), and Suwannee River NOM (SR-NOM). The QD was composed of a CdSe core, ZnS shell, and polyethylene glycol coating. The average size of the investigated QD was 4.8, 56.5, and 25.0 nm determined by transmission electron microscopy, dynamic light scattering, and asymmetric flow field-flow fractionation, respectively. The relative hydrophobicity of NOM was investigated using both specific UV absorbance at 254 nm and XAD-8/4 resins. The sorption of NOM on the QD was measured using a fluorescence quenching method. The highest hydrophobicity was exhibited by the SR-NOM, while the lowest was recorded for the DL-NOM. All tested NOMs significantly reduced the acute toxicity of D. magna when adsorbed to QD, and the order of effectiveness for each NOM was as follows: SR-NOM > EfOM > YS-NOM > DL-NOM. The sorption of NOM on the QD surface caused a decrease in the fluorescence intensity of QD at increasing NOM concentration. This suggests that the NOM coating influenced the physicochemical characteristics of QD in the internal organs of D. magna by inducing a reduced bioavailability. Results from this study revealed that NOM with relatively high hydrophobicity had a greater capability of inducing toxicity mitigation.

previous article Efficiency of protective dermal equipment against silver nanoparticles with water aerosol

next article Mn–ferrite nanoparticles via reverse microemulsions: synthesis and characterization

Dont have a licence yet? Then find out more about our products and how to get one now:

Springer Professional "Wirtschaft+Technik"

Online-Abonnement

Mit Springer Professional "Wirtschaft+Technik" erhalten Sie Zugriff auf:

über 102.000 Bücher
über 537 Zeitschriften

aus folgenden Fachgebieten:

Automobil + Motoren
Bauwesen + Immobilien
Business IT + Informatik
Elektrotechnik + Elektronik
Energie + Nachhaltigkeit
Finance + Banking
Management + Führung
Marketing + Vertrieb
Maschinenbau + Werkstoffe
Versicherung + Risiko

Jetzt Wissensvorsprung sichern!

inform now

Springer Professional "Technik"

Online-Abonnement

Mit Springer Professional "Technik" erhalten Sie Zugriff auf:

über 67.000 Bücher
über 390 Zeitschriften

aus folgenden Fachgebieten:

Automobil + Motoren
Bauwesen + Immobilien
Business IT + Informatik
Elektrotechnik + Elektronik
Energie + Nachhaltigkeit
Maschinenbau + Werkstoffe

Jetzt Wissensvorsprung sichern!

inform now

Bakalova R, Ohba H, Zhelev Z, Nagase T, Jose R, Ishikawa M, Baba Y (2004) Quantum dot anti-CD conjugates: are they potential photosensitizers or potentiators of classical photosensitizing agents in photodynamic therapy of cancer? Nano Lett 4:1567–1573CrossRef

Boylston E (2002) Staining and other microscopic techniques for textiles. Microsc Microanal 8(Suppl. 2):192–193

Cho J, Park Y-J, Sun H, Kim S, Yoon Y (2006) Measurements of effective sizes and diffusivities of nano-colloids and micro-particles. Colloids Surf A 274:43–47CrossRef

Cundy AB, Hopkinson L, Whitby RLD (2008) Use of iron-based technologies in contaminated land and groundwater remediation: a review. Sci Total Environ 400:42–51CrossRef

Deerinck TJ (2008) The application of fluorescent quantum dots to confocal, multiphoton, and electron microscopic imaging. Toxicol Pathol 36:112–116CrossRef

Derfus AM, Chan WCW, Bhatia SN (2004) Probing the cytotoxicity of semiconductor quantum dots. Nano Lett 4:11–18CrossRef

Evident Technologies (2008) www.evidenttech.com/products/evidots.html

Finney DJ (1971) Probit analysis, 3rd edn. Cambridge University Press, London

Fraunhofer W, Winter G (2004) The use of asymmetrical flow field-flow fractionation in pharmaceutics and biopharmaceutics. Eur J Pharm Biopharm 58:369–383CrossRef

Gaunt JA, Knight AE, Windsor SA, Chechik V (2005) Stability and quantum yield effects of small molecule additives on solutions of semiconductor nanoparticles. J Colloid Interface Sci 290:437–443CrossRef

Gauthler TD, Shane EC, Guerln WF, Seitz WR, Grant CL (1986) Fluorescence quenching method for determining equilibrium constants for polycyclic aromatic hydrocarbons binding to dissolved humic materials. Environ Sci Technol 20:1162–1166CrossRef

Ghali M (2010) Static quenching of bovine serum albumin conjugated with small size CdS nanocrystalline quantum dots. J Lumin 130:1254–1257CrossRef

Hardman R (2006) A toxicologic review of quantum dots: toxicity depends on physiochemical and environmental factors. Environ Health Perspect 114:165–172CrossRef

Hoshino A, Fujioka K, Oku T, Suga M, Sasaki YF, Ohta T, Yasuhara M, Suzuki K, Yamamoto K (2004) Physicochemical properties and cellular toxicity of nanocrystal quantum dots depend on their surface modification. Nano Lett 4:2163–2169CrossRef

Hyung H, Kim J-h (2008) Natural organic matter (NOM) adsorption to multi-walled carbon nanotubes: Effect of nom characteristics and water quality parameters. Environ Sci Technol 42:4416–4421CrossRef

Hyung H, Fortner JD, Hughes JB, Kim J-h (2007) Natural organic matter stabilizes carbon nanotubes in the aqueous phase. Environ Sci Technol 41:179–184CrossRef

Jia G, Wang H, Yan L, Wang X, Pei R, Yan T, Zhao Y, Guo X (2005) Cytotoxicity of carbon nanomaterials: single-wall nanotubes, multi-wall nanotubes, and fullerene. Environ Sci Technol 39:1378–1383CrossRef

Kloepfer JA, Bradforth SE, Nadeau JL (2005) Photophysical properties of biologically compatible CdSe quantum dot structures. J Phys Chem 109:9996–10003

Lee N, Amy G, Croué J-P, Buisson H (2004) Identification and understanding of fouling in low-pressure membrane (MF/UF) filtration by natural organic matter (NOM). Water Res 38:4511–4523CrossRef

Lee S, Ang WS, Elimelech M (2006) Fouling of reverse osmosis membranes by hydrophilic organic matter: Implications for water reuse. Desalination 187:313–321CrossRef

Li D, Lyon DY, Li Q, Alvarez PJ (2008) Effect of soil sorption and aquatic natural organic matter on the antibacterial activity of a fullerene water suspension. Environ Toxicol Chem 27:1888–1894CrossRef

Lovern SB, Strickler JR, Klaper R (2007) Behavioral and physiological changes in Daphnia magna when exposed to nanoparticle suspensions (titanium dioxide, nono-C₆₀, and C₆₀H_xC₇₀H_x). Environ Sci Technol 41:4465–4470CrossRef

Mahendra S, Zhu H, Colvin VL, Alvarez PJ (2008) Quantum dot weathering results in microbial toxicity. Environ Sci Technol 42:9424–9430CrossRef

Maier KJ, Foe CG, Knight AW (1993) Comparative toxicity of selenate, selenite, seleno-DL-methionine and seleno-DL-cystine to Daphnia magna. Environ Toxicol Chem 12:755–763

Manciulea A, Baker A, Lead JR (2009) A fluorescence quenching study of the interaction of Suwannee River fulvic acid with iron oxide nanoparticles. Chemosphere 76:1023–1027CrossRef

Moon J, Cho J (2005) Investigation of nano-colloid transport in UF membranes using flow field-flow fractionation (flow FFF) and an irreversible thermodynamic transport model. Desalination 179:151–159CrossRef

Moon J, Kim SH, Cho J (2006) Characterizations of natural organic matter as nano particle using flow field-flow fractionation. Colloids Surf A287:232–236

Navarro DAG, Watson DF, Aga DS, Banerjee S (2009) Natural organic matter-mediated phase transfer of quantum dots in the aquatic environment. Environ Sci Technol 43:677–682CrossRef

Oberdőrster E (2004) Manufactured nanomaterials (fullerenes, C₆₀) induce oxidative stress in the brain of juvenile largemouth bass. Environ Health Perspect 112:1058–1062CrossRef

Oh HI, Hoff JE, Amstrong GS, Haff LA (1980) Hydrophobic interaction in tannin-protein complexes. J Agric Food Chem 28:394–398CrossRef

Park N, Kwon B, Kim IS, Cho J (2005) Biofouling potential of various NF membranes with respect to bacteria and their soluble microbial products (SMP): characterizations, flux decline, and transport parameters. J Membr Sci 258:43–54CrossRef

Roberts AP, Mount AS, Seda B, Souther J, Qiao R, Lin S, Ke P, Rao AM, Klaine SJ (2007) In vivo biomodification of lipid-coated carbon nanotubes by Daphnia magna. Environ Sci Technol 41:3025–3029CrossRef

Ryman-Rasmussen JP, Riviere JE, Nonteiro-Riviere NA (2006) Surface coatings determine cytotoxicity and irritation potential of quantum dot nanoparticles in epidermal keratinocytes. J Invest Dermatol 127:143–153CrossRef

Sarathchandra WD, Mainwaring DE (2005) Effect of poly(ethylene glycol) on the hydrophobic interactions and rheology of proanthocyanidin biopolymers from pinus radiata. J Appl Polym Sci 97:1254–1260CrossRef

Schlautman MA, Morgan JJ (1993) Binding of a fluorescent hydrophobic organic probe by dissolved humic substances and organically-coated aluminum oxide surfaces. Environ Sci Technol 27:2523–2532CrossRef

Shaw JR, Dempsey TD, Chen CY, Hamilton JW, Folt CL (2006) Comparative toxicity of cadmium, zinc, and mixtures of cadmium and zinc to daphnids. Environ Toxicol Chem 25:182–189CrossRef

Slaveykova VI, Startchev K (2009) Effect of natural organic matter and green microalga on carboxyl-polyethylene glycol coated CdSe/ZnS quantum dots stability and transformations under freshwater conditions. Environ Pollut 157:3445–3450CrossRef

U.S. EPA (1993) Methods for measuring the acute toxicity of effluents and receiving waters to freshwater and marine organisms. Cincinnati, EPA/600/4-90/027F

Wiesner MR, Lowry GV, Alvarez PJ, Dionysiou D (2006) Assessing the risks of manufactured nanomaterials. Environ Sci Technol 40:4336–4345CrossRef

Willis J, Morris J (2007) Nanotechnology white paper. 100/B-07/001. U.S. EPA, Washington, DC. http://www.epa.gov/osa/pdfs/nanotech/epa-nanotechnology-whitepaper-0207.pdf

Yamamoto H, Liljestrand HM, Shimizu Y, Morita M (2003) Effects of physical-chemical characteristics on the sorption of selected endocrine disruptors by dissolved organic matter surrogates. Environ Sci Technol 37:2646–2657CrossRef

Yohannes G, Holappa S, Wiedmer SK, Andersson T, Tenhu H, Riekkola ML (2005) Polyelectrolyte complexes of poly(methacryloxyethyl trimethylammonium chloride) and poly(ethylene oxide)-block-poly(sodium methacrylate) studied by asymmetrical flow field-flow fractionation and dynamic light scattering. Anal Chim Acta 542:222–229CrossRef

Yoon Y, Westerhoff P, Snyder SA (2005) Adsorption of ³H-labled 17-β estradiol on powdered activated carbon. Water Air Soil Pollut 166:343–351CrossRef

Yu WW, Chang E, Falkner JC, Zhang J, Al-Somali AM, Sayes CM, Johns J, Krezek R, Colvin VL (2007) Forming biocompatible and nonaggregated nanocrystals in water using amphiphilic polymers. J Am Chem Soc 129:2871–2879CrossRef

Title: Biotoxicity of nanoparticles: effect of natural organic matter
Authors: Sungyun Lee
Kitae Kim
H. K. Shon
Sang Don Kim
Jaeweon Cho
Publication date: 01-07-2011
Publisher: Springer Netherlands
Published in: Journal of Nanoparticle Research / Issue 7/2011
Print ISSN: 1388-0764
Electronic ISSN: 1572-896X
DOI: https://doi.org/10.1007/s11051-010-0204-z

Springer Professional

Abstract

Please log in to get access to your license.

Dont have a licence yet? Then find out more about our products and how to get one now:

Springer Professional "Wirtschaft+Technik"

Springer Professional "Technik"

Other articles of this Issue 7/2011

Stabilization of triangular and heart-shaped plane silver nanoparticles using 2-thiobarbituric acid

Controlling morphology and structure of nanocrystalline cadmium sulfide (CdS) by tailoring solvothermal processing parameters

Controlled synthesis of Sb2O3 nanoparticles by chemical reducing method in ethylene glycol

First principles study of p-type doping in SiC nanowires: role of quantum effect

Colloidal stability of silver nanoparticles in biologically relevant conditions

Zinc-phosphate nanoparticles with reversibly attached TNF-α analogs: an interesting concept for potential use in active immunotherapy

Premium Partners