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2013 | OriginalPaper | Chapter

Cell-free Biosystems in the Production of Electricity and Bioenergy

Authors : Zhiguang Zhu, Tsz Kin Tam, Y.-H. Percival Zhang

Published in: Fundamentals and Application of New Bioproduction Systems

Publisher: Springer Berlin Heidelberg

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Abstract

Increasing needs of green energy and concerns of climate change are motivating intensive R&D efforts toward the low-cost production of electricity and bioenergy, such as hydrogen, alcohols, and jet fuel, from renewable sugars. Cell-free biosystems for biomanufacturing (CFB2) have been suggested as an emerging platform to replace mainstream microbial fermentation for the cost-effective production of some biocommodities. As compared to whole-cell factories, cell-free biosystems comprised of synthetic enzymatic pathways have numerous advantages, such as high product yield, fast reaction rate, broad reaction condition, easy process control and regulation, tolerance of toxic compound/product, and an unmatched capability of performing unnatural reactions. However, issues pertaining to high costs and low stabilities of enzymes and cofactors as well as compromised optimal conditions for different source enzymes need to be solved before cell-free biosystems are scaled up for biomanufacturing. Here, we review the current status of cell-free technology, update recent advances, and focus on its applications in the production of electricity and bioenergy.

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Title: Cell-free Biosystems in the Production of Electricity and Bioenergy
Authors: Zhiguang Zhu
Tsz Kin Tam
Y.-H. Percival Zhang
Publisher: Springer Berlin Heidelberg
Book: Fundamentals and Application of New Bioproduction Systems
Print ISBN: 978-3-642-41520-3

Electronic ISBN: 978-3-642-41521-0

Copyright Year: 2013
DOI: https://doi.org/10.1007/10_2013_201