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2013 | OriginalPaper | Chapter

Computational Modeling of Gastrointestinal Fluid Dynamics

Authors : Maria J. Ferrua, R. Paul Singh

Published in: New Advances in Gastrointestinal Motility Research

Publisher: Springer Netherlands

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Abstract

Knowledge of the fluid dynamic behavior of gastrointestinal (GI) contents during digestion is essential to further understand and model the bioavailability of nutrients and pharmaceuticals in health and disease. The dynamics that develop within the GI tract are the result of a complex and self-regulated interplay between the physical properties of the intraluminal contents and the motor responses of the GI wall. Recent advances in the characterization of GI motility patterns have facilitated the use of engineering simulation tools to investigate the mechanisms driving different GI functions. In this chapter, current research aimed at using computational fluid dynamic (CFD) techniques to predict the flow and mixing behavior of gastric and small intestinal contents during digestion will be reviewed. The unique capability and potential applications of this new approach to advance research in the food and health sectors will be discussed.

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previous chapter Spatiotemporal Mapping Techniques for Quantifying Gut Motility

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Title: Computational Modeling of Gastrointestinal Fluid Dynamics
Authors: Maria J. Ferrua
R. Paul Singh
Publisher: Springer Netherlands
Book: New Advances in Gastrointestinal Motility Research
Print ISBN: 978-94-007-6560-3

Electronic ISBN: 978-94-007-6561-0

Copyright Year: 2013
DOI: https://doi.org/10.1007/978-94-007-6561-0_13