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Published in:
2009 | OriginalPaper | Chapter
Current Efforts to Integrate Biological Pathway Information
Authors : Daniel Glez-Peña, Rubén Domínguez, Gonzalo Gómez-López, David G. Pisano, Florentino Fdez-Riverola
Published in: Distributed Computing, Artificial Intelligence, Bioinformatics, Soft Computing, and Ambient Assisted Living
Publisher: Springer Berlin Heidelberg
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PathJam is a new comprehensive and freely accessible web-server application integrating scattered human pathway annotation from several public sources. The tool has been designed to be intuitive for wet-lab users providing statistical enrichment analysis of pathway annotation for a given gene list of interest. Results are displayed in several interactive and downloadable views (graphs, spread-sheets, etc.) facilitating the biological interpretation of the gene lists. Moreover, PathJam allows users to build their own gene sets files in order to use them in gene set enrichment-based analysis. Finally, a simplified version of PathJam has been also implemented as a widget and is currently available for CARGO users.